Works (7)

Updated: July 5th, 2023 15:40

2017 journal article

Climate projections of spatial variations in coastal storm surges along the Gulf of Mexico and U.S. east coast

Journal of Ocean University of China, 16(1), 1–7.

author keywords: storm surge; sea surface winds; climate change; regional ocean
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
14. Life Below Water (Web of Science)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2017 journal article

Direct screening of enzyme activity using infrared matrix-assisted laser desorption electrospray ionization

RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 31(22), 1868–1874.

MeSH headings : Drug Discovery / methods; Enzyme Assays / methods; High-Throughput Screening Assays / methods; Isocitrate Dehydrogenase / metabolism; Isocitrates / metabolism; Ketoglutaric Acids / metabolism; Models, Chemical; NADP / metabolism; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: The utility of infrared matrix-assisted laser desorption electrospray ionization for monitoring an enzymatic reaction directly from a biological buffer system with no sample cleanup and at high throughput is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

IR-MALDESI Mass Spectrometry Imaging at 50 Micron Spatial Resolution

Journal of The American Society for Mass Spectrometry, 28(10), 2099–2107.

By: M. Bokhart n, J. Manni, K. Garrard n, M. Ekelöf n, M. Nazari n & D. Muddiman n

author keywords: Mass spectrometry imaging; IR-MALDESI; Tissue imaging; Spatial resolution; Laser focusing
TL;DR: This work presents MSI using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) at 50 μm resolution, using an adjustable iris, beam expander, and an aspherical focusing lens to reduce tissue ablation diameters for MSI at high resolution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2016 journal article

Enhanced Lipidome Coverage in Shotgun Analyses by using Gas-Phase Fractionation

JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 27(11), 1735–1744.

By: M. Nazari n & D. Muddiman n

author keywords: Shotgun lipidomics; Gas-phase fractionation; Lipids; Hen model; Lipid metabolism; Polarity switching; Q Exactive Plus
MeSH headings : Animals; Chickens; Female; Glycerophospholipids; Ions; Lipids / chemistry; Tandem Mass Spectrometry
TL;DR: This comprehensive analysis of the lipidome can serve as a species- and tissue-specific database for confident identification of other MS-based datasets, such as mass spectrometry imaging. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Whole-body mass spectrometry imaging by infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI)

Jove-Journal of Visualized Experiments, (109).

By: M. Nazari, M. Bokhart & D. Muddiman

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Cellular-level mass spectrometry imaging using infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) by oversampling

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(8), 2265–2271.

By: M. Nazari n & D. Muddiman n

author keywords: Mass spectrometry imaging; Infrared; MALDESI; Cellular analysis; Oversampling; Tissue analysis; Lipids
MeSH headings : Cells / chemistry; Cells / metabolism; Cervix Uteri / chemistry; Cervix Uteri / metabolism; Cholesterol / metabolism; Female; Humans; Microtomy; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
TL;DR: Infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI) imaging of cervical tissue sections was performed using a spot-to-spot distance of 10 μm by utilizing the method of oversampling, where the target plate is moved by a distance that is less than the desOrption radius of the laser. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Influence of C-Trap Ion Accumulation Time on the Detectability of Analytes in IR-MALDESI MSI

ANALYTICAL CHEMISTRY, 87(20), 10483–10490.

By: E. Rosen n, M. Bokhart n, M. Nazari n & D. Muddiman n

MeSH headings : Ions / chemistry; Lasers; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry, Infrared; Time Factors; Xenobiotics / analysis
TL;DR: Reducing the C-trap ion accumulation time resulted in increased ion abundance by up to 3 orders of magnitude for analytes ranging from xenobiotics to endogenous lipids, and facilitated the reduction of voxel-to-voxel variability by more than 3-fold. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

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