Melanie Patricia Madsen

2022 article

Ceftazidime pharmacokinetics in dogs after intravenous injection and delivered with the RxActuator Mini-Infuser infusion pump

Papich, M. G., Madsen, M., Messenger, K., & Enomoto, H. (2022, May 6). JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, Vol. 5.

By: M. Papich n, M. Madsen n, K. Messenger n & H. Enomoto n

author keywords: antimicrobial; canine; cephalosporin; half-life; mean inhibitory concentration
MeSH headings : Animals; Ceftazidime / pharmacokinetics; Dogs; Humans; Infusion Pumps / veterinary; Infusions, Intravenous / veterinary; Injections, Intravenous / veterinary
TL;DR: This study demonstrated the successful application of the RxActuator Mini-Infuser wearable SC constant rate infusion pump for delivering an antimicrobial needed for serious, and sometimes resistant, infections in dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 7, 2022

2022 journal article

Effects of housing environment on oral absorption of acetaminophen in healthy Beagles

AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(1), 80–85.

By: M. Madsen n, H. Enomoto n, K. Messenger n & M. Papich n

MeSH headings : Acetaminophen; Animals; Cross-Over Studies; Dogs; Gastric Emptying; Housing
TL;DR: It is suggested that in dogs, housing environment (normal environment vs a cage in an unfamiliar environment) did not significantly affect oral absorption and, by extension, gastric emptying of acetaminophen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 7, 2022

2022 article

Pharmacokinetics of intravenous, oral transmucosal, and intranasal buprenorphine in healthy male dogs

Enomoto, H., Love, L., Madsen, M., Wallace, A., & Messenger, K. M. (2022, April 21). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS.

By: H. Enomoto n, L. Love n, M. Madsen n, A. Wallace n & K. Messenger n

author keywords: buprenorphine; dog; intranasal; oral transmucosal; pharmacokinetics; Simbadol (TM)
MeSH headings : Administration, Intravenous / veterinary; Administration, Mucosal; Administration, Oral; Analgesics; Animals; Biological Availability; Buprenorphine / pharmacokinetics; Cross-Over Studies; Dogs; Male
TL;DR: Intranasal and OTM routes of administration of concentrated buprenorphine in dogs may allow for the provision of analgesic care at home. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 2, 2022

2019 journal article

Pharmacokinetics of levofloxacin following oral administration of a generic levofloxacin tablet and intravenous administration to dogs

AMERICAN JOURNAL OF VETERINARY RESEARCH, 80(10), 957–962.

By: M. Madsen n, K. Messenger n & M. Papich n

MeSH headings : Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid / veterinary; Cross-Over Studies; Dogs / metabolism; Female; Half-Life; Levofloxacin / administration & dosage; Levofloxacin / pharmacokinetics; Male; Tablets
TL;DR: In these dogs, levofloxacin was well absorbed when administered orally, and a dose of approximately 25 mg/kg was sufficient to reach pharmacokinetic-pharmacodynamic targets for treating infections with susceptible Enterobacteriaceae or Pseudomonas aeruginosa. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020

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