Monnat Pongpanich

Works (2)

Updated: July 5th, 2023 15:48

2011 journal article

Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.

By: J. Tzeng n, D. Zhang n, M. Pongpanich n, C. Smith  n, M. McCarthy *, M. Sale *, B. Worrall *, F. Hsu *, D. Thomas *, P. Sullivan*

MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
TL;DR: A similarity-based regression method for assessing the main genetic and interaction effects of a group of markers on quantitative traits and is an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium blocks, genes, or pathways in whole-genome analysis. (via Semantic Scholar)
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Added: August 6, 2018

2010 journal article

A quality control algorithm for filtering SNPs in genome-wide association studies

BIOINFORMATICS, 26(14), 1731–1737.

By: M. Pongpanich n, P. Sullivan  n & J. Tzeng n

MeSH headings : Algorithms; Genome; Genome-Wide Association Study / methods; Genome-Wide Association Study / standards; Polymorphism, Single Nucleotide; Quality Control
TL;DR: An algorithm that is based on principal component analysis and clustering analysis to identify low-quality SNPs and suggests that with the same or fewer SNPs excluded, the proposed algorithm tends to give a similar or lower value of lambda, a reduced number of false associations, and retains all true associations. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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