2009 journal article

Anti-inflammatory effects of intravenously administered lidocaine hydrochloride on ischemia-injured jejunum in horses

American Journal of Veterinary Research, 70(10), 1259–1268.

By: V. Cook n, J. Jones Shults n, M. McDowell n, N. Campbell n, J. Davis n, J. Marshall n, A. Blikslager n

Contributors: V. Cook n, J. Jones Shults n, M. McDowell n, N. Campbell n, J. Davis n, J. Marshall n, A. Blikslager n

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / adverse effects; Clonixin / adverse effects; Clonixin / analogs & derivatives; Female; Gene Expression Regulation, Enzymologic / drug effects; Horse Diseases / chemically induced; Horse Diseases / drug therapy; Horses; Intestinal Diseases / chemically induced; Intestinal Diseases / veterinary; Ischemia / chemically induced; Jejunum / drug effects; Lidocaine / therapeutic use; Male; Prostaglandin-Endoperoxide Synthases / genetics; Prostaglandin-Endoperoxide Synthases / metabolism
TL;DR: In horses with ischemia-injured jejunum, lidocaine administered IV reduced plasma prostaglandin E(2) metabolite concentration and mucosal COX-2 expression and coadministration of lidocane with flunixin ameliorated the flunxin-induced increase in mucosal neutrophil counts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018

2008 journal article

Attenuation of ischaemic injury in the equine jejunum by administration of systemic lidocaine

Equine Veterinary Journal, 40(4), 353–357.

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

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