Michael Robert McLaren

https://orcid.org/0000-0003-1575-473X

microbiome, evolutionary theory, population genetics, microbial ecology, metagenomics, adaptation

Works (14)

Updated: April 11th, 2023 10:13
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2022 article

Implications of taxonomic bias for microbial differential-abundance analysis

McLaren, M. R., Nearing, J. T., Willis, A. D., Lloyd, K. G., & Callahan, B. J. (2022, August 19).

By: M. McLaren , J. Nearing *, A. Willis*, K. Lloyd* & B. Callahan 

Source: ORCID
Added: August 24, 2022

2021 journal article

Clostridioides difficile exploits toxin-mediated inflammation to alter the host nutritional landscape and exclude competitors from the gut microbiota

NATURE COMMUNICATIONS, 12(1).

By: J. Fletcher, C. Pike, R. Parsons n, A. Rivera, M. Foley, M. McLaren , S. Montgomery*, C. Theriot

Sources: ORCID, Web Of Science
Added: January 20, 2021

2021 review

Evaluating Use Cases for Human Challenge Trials in Accelerating SARS-CoV-2 Vaccine Development

[Review of ]. CLINICAL INFECTIOUS DISEASES, 72(4), 710–715.

By: L. Nguyen *, C. Bakerlee *, T. McKelvey*, S. Rose*, A. Norman*, N. Joseph*, D. Manheim *, M. McLaren  ...

author keywords: vaccine evaluation; COVID-19; pandemic; controlled human infection; human challenge trial
Sources: Web Of Science, ORCID
Added: June 10, 2021

2020 journal article

Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota

ANAEROBE, 66.

By: R. Thanissery  n, M. McLaren , A. Rivera, A. Reed, N. Betrapally, T. Burdette, J. Winston, M. Jacob, B. Callahan , C. Theriot

author keywords: C. difficile; C. hiranonis; Microbiome; Ribotype; Antibiotic resistance; Animal; Canine; Equine; Feline
Sources: Web Of Science, ORCID
Added: January 11, 2021

2020 journal article

Pathogen resistance may be the principal evolutionary advantage provided by the microbiome

Philosophical Transactions of the Royal Society B: Biological Sciences, 375(1808), 20190592.

By: M. McLaren  & B. Callahan 

author keywords: colonization resistance; commensal bacteria; defensive symbionts; evolution of immunity; host-microbiome interactions; microbiome
Source: ORCID
Added: August 12, 2020

2020 journal article

Understanding and interpreting community sequencing measurements of the vaginal microbiome

BJOG: An International Journal of Obstetrics & Gynaecology, 127(2), 139–146.

By: H. Berman n, . McLaren n & B. Callahan 

author keywords: 16S rRNA gene; amplicon sequencing; metagenomics; metatranscriptomics; vaginal microbiome
Source: ORCID
Added: November 2, 2019

2019 article

Characterization of C. difficile strains isolated from companion animals and the associated changes in the host fecal microbiota

Thanissery, R., McLaren, M., Rivera, A., Reed, A. D., Betrapally, N., Burdette, T., … Theriot, C. (2019, October).

By: R. Thanissery  n, M. McLaren , A. Rivera n, A. Reed  n, N. Betrapally n, T. Burdette n, J. Winston  n, M. Jacob n, B. Callahan  n, C. Theriot  n

Source: ORCID
Added: December 9, 2019

2019 journal article

Consistent and correctable bias in metagenomic sequencing experiments

ELife.

By: M. McLaren , A. Willis* & B. Callahan 

Source: ORCID
Added: September 10, 2019

2019 journal article

Consistent and correctable bias in metagenomic sequencing measurements

BioRxiv, 2, 559831.

By: M. McLaren , A. Willis* & B. Callahan 

Source: ORCID
Added: February 26, 2019

2019 journal article

Current State of and Future Opportunities for Prediction in Microbiome Research: Report from the Mid-Atlantic Microbiome Meet-up in Baltimore on 9 January 2019.

MSystems, 10.

By: E. Sakowski*, G. Uritskiy*, R. Cooper*, M. Gomes*, . McLaren n, J. Meisel*, R. Mickol*, C. Mintz* ...

author keywords: microbiome; bioinformatics; metagenomics; prediction; machine learning; conceptual models; quantitative models
Source: ORCID
Added: December 9, 2019

2018 article

In Nature, There Is Only Diversity

MBIO, Vol. 9.

By: M. McLaren  & B. Callahan 

author keywords: metagenomics; microbial ecology; microbiome
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Fitness-valley crossing in subdivided asexual populations

BioRxiv.

By: M. McLaren 

Source: ORCID
Added: February 11, 2019

2013 journal article

The Atacama Cosmology Telescope: Cosmological parameters from three seasons of data

Journal of Cosmology and Astroparticle Physics, 2013(10).

author keywords: CMBR experiments; Sunyaev-Zeldovich effect; physics of the early universe; cosmological parameters from CMBR
Source: ORCID
Added: February 11, 2019

2011 journal article

The Atacama cosmology telescope: Detection of Sunyaev-Zel'dovich decrement in groups and clusters associated with luminous red galaxies

Astrophysical Journal, 736(1).

By: N. Hand *, J. Appel*, N. Battaglia*, J. Richard Bond, S. Das*, M. Devlin*, J. Dunkley*, R. Dünner* ...

author keywords: cosmic background radiation; cosmology: observations; galaxies: clusters: general
Source: ORCID
Added: February 11, 2019

Employment

Updated: March 15th, 2022 21:14

2022 - present

Massachusetts Institute of Technology Cambridge, Massachusetts, US
Research Scientist Media Lab

2017 - 2022

North Carolina State University Raleigh, North Carolina, US
Postdoc Population Health and Pathobiology

Education

Updated: November 15th, 2016 20:49

2010 - 2016

Stanford University Stanford, CA, US
PhD Biology

2005 - 2009

University of Pennsylvania Philadelphia, PA, US
BA Mathematics