Mani Ratnam Rai

Works (8)

Updated: April 25th, 2025 19:44

2024 article

Intelligent Beam Optimization for Light-Sheet Fluorescence Microscopy through Deep Learning

Li, C., Rai, M. R., Cai, Y., Ghashghaei, H. T., & Greenbaum, A. (2024, January 1). Intelligent Computing.

By: C. Li  n, M. Rai n, Y. Cai  n, H. Ghashghaei n & A. Greenbaum*

topics (OpenAlex): Advanced Fluorescence Microscopy Techniques; Image Processing Techniques and Applications; Optical Coherence Tomography Applications
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Source: Web Of Science
Added: January 13, 2025

2024 article

Roadmap on computational methods in optical imaging and holography [invited]

Rosen, J., Alford, S., Allan, B., Anand, V., Arnon, S., Arockiaraj, F. G., … Ahmad, A. (2024, August 29). Applied Physics B.

By: J. Rosen *, S. Alford *, B. Allan *, V. Anand *, S. Arnon *, F. Arockiaraj *, J. Art *, B. Bai * ...

topics (OpenAlex): Digital Holography and Microscopy; Random lasers and scattering media; Advanced Optical Imaging Technologies
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4. Quality Education (OpenAlex)
Source: Web Of Science
Added: September 16, 2024

2024 journal article

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

Frontiers in Pharmacology, 15.

By: A. Moatti n , S. Connard n, N. De Britto n, W. Dunn *, S. Rastogi n, M. Rai n, L. Schnabel n , F. Ligler* ...

author keywords: intratympanic; inner ear; fluid simulation; round window membrane; pigs; swine; pharmacokinetics
topics (OpenAlex): Vestibular and auditory disorders; Hearing, Cochlea, Tinnitus, Genetics; Ear Surgery and Otitis Media
TL;DR: The potential of using pigs as a large animal model for studying inner ear pharmacokinetic studies of the inner ear using pigs is demonstrated and the diffusion time and drug concentrations reported align closely with the limited data available from human studies. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 19, 2024

2023 article

Deep learning-based adaptive optics for light sheet fluorescence microscopy

Rai, M. R., Li, C., Ghashghaei, H. T., & Greenbaum, A. (2023, May 19). Biomedical Optics Express.

By: M. Rai n, C. Li n, H. Ghashghaei n & A. Greenbaum n

topics (OpenAlex): Advanced Fluorescence Microscopy Techniques; Optical Coherence Tomography Applications; Photoacoustic and Ultrasonic Imaging
TL;DR: It is shown that the application of correction using a deformable mirror greatly improves image quality and two conceptually different network architectures are compared; one that shares convolutional features and another that estimates each aberration independently. (via Semantic Scholar)
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Source: Web Of Science
Added: July 24, 2023

2023 article

Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model

Ahmad, S., Wrennall, J. A., Goriounova, A. S., Sekhri, M., Iskarpatyoti, J. A., Ghosh, A., … Tarran, R. (2023, November 16). American Journal of Respiratory and Critical Care Medicine.

By: S. Ahmad *, J. Wrennall*, A. Goriounova *, M. Sekhri*, J. Iskarpatyoti*, A. Ghosh *, S. Abdelwahab *, A. Voeller* ...

author keywords: peptide; ICRAC; ARDS; pneumonia; neutrophilia
MeSH headings : Humans; Mice; Animals; Calcium Channels / metabolism; Calcium Channels / pharmacology; Calcium / metabolism; HEK293 Cells; Methicillin-Resistant Staphylococcus aureus / metabolism; Calcium Signaling; Inflammation / drug therapy; Lung / metabolism; Respiratory Distress Syndrome / drug therapy; Pneumonia, Bacterial / drug therapy; ORAI1 Protein / metabolism; ORAI1 Protein / pharmacology
topics (OpenAlex): Ion Channels and Receptors; Respiratory and Cough-Related Research; Asthma and respiratory diseases
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Source: Web Of Science
Added: May 20, 2024

2022 article

Illumination angle correction during image acquisition in light-sheet fluorescence microscopy using deep learning

Li, C., Rai, M. R., Ghashghaei, H. T., & Greenbaum, A. (2022, January 6). Biomedical Optics Express.

By: C. Li n, M. Rai n, H. Ghashghaei n & A. Greenbaum n

topics (OpenAlex): Advanced Fluorescence Microscopy Techniques; Image Processing Techniques and Applications; Cell Image Analysis Techniques
TL;DR: This study provides a framework that can correct the angle of the light-sheet and improve the overall image quality in high-resolution LSFM 3D image acquisition. (via Semantic Scholar)
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Source: Web Of Science
Added: February 14, 2022

2022 article

Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat

Newell, A. J., Kapps, V. A., Cai, Y., Rai, M. R., Armour, G. S., Horman, B. M., … Patisaul, H. B. (2022, December 22). Toxicological Sciences, Vol. 191, pp. 357–373.

By: A. Newell n, V. Kapps n, Y. Cai  n, M. Rai n, G. Armour n, B. Horman n, K. Rock n, S. Witchey n, A. Greenbaum n, H. Patisaul n 

author keywords: neurodevelopment; monoamine; OPFR; OPE; flame retardants; neurotransmitters; neurotoxicity; neurotoxicology; prenatal; reproductive and developmental toxicology; mesocortical dopamine system; tissue clearing light sheet microscopy.
MeSH headings : Animals; Female; Male; Rats; Dopamine / metabolism; Fetal Development / drug effects; Flame Retardants / toxicity; Maternal Exposure / adverse effects; Neurotoxicity Syndromes / etiology; Organophosphates / toxicity; Serotonin / metabolism
topics (OpenAlex): Toxic Organic Pollutants Impact; Effects and risks of endocrine disrupting chemicals; Carcinogens and Genotoxicity Assessment
TL;DR: Results indicate maternal exposure to OPFRs alters the development trajectory of the embryonic dopaminergic system and adds to growing evidence of OPFR developmental neurotoxicity. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024

2022 article

Quantitative analysis of illumination and detection corrections in adaptive light sheet fluorescence microscopy

Rai, M. R., Li, C., & Greenbaum, A. (2022, April 18). Biomedical Optics Express.

By: M. Rai n, C. Li n & A. Greenbaum n

topics (OpenAlex): Advanced Fluorescence Microscopy Techniques; Cell Image Analysis Techniques; Photoacoustic and Ultrasonic Imaging
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Source: Web Of Science
Added: May 31, 2022

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