Mani Ratnam Rai

Works (5)

Updated: April 5th, 2024 14:57

2024 journal article

Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs

FRONTIERS IN PHARMACOLOGY, 15.

By: A. Moatti n, S. Connard n, N. De Britto n, W. Dunn*, S. Rastogi n, M. Rai n, L. Schnabel n, F. Ligler* ...

author keywords: intratympanic; inner ear; fluid simulation; round window membrane; pigs; swine; pharmacokinetics
TL;DR: The potential of using pigs as a large animal model for studying inner ear pharmacokinetic studies of the inner ear using pigs is demonstrated and the diffusion time and drug concentrations reported align closely with the limited data available from human studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: February 19, 2024

2023 journal article

Deep learning-based adaptive optics for light sheet fluorescence microscopy

BIOMEDICAL OPTICS EXPRESS, 14(6), 2905–2919.

TL;DR: It is shown that the application of correction using a deformable mirror greatly improves image quality and two conceptually different network architectures are compared; one that shares convolutional features and another that estimates each aberration independently. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 24, 2023

2023 journal article

Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat

TOXICOLOGICAL SCIENCES, 191(2), 357–373.

By: A. Newell n, V. Kapps n, Y. Cai n, M. Rai, G. St Armour n, B. Horman n, K. Rock n, S. Witchey n, A. Greenbaum n, H. Patisaul n

author keywords: neurodevelopment; monoamine; OPFR; OPE; flame retardants; neurotransmitters; neurotoxicity; neurotoxicology; prenatal; reproductive and developmental toxicology; mesocortical dopamine system; tissue clearing light sheet microscopy.
TL;DR: Results indicate maternal exposure to OPFRs alters the development trajectory of the embryonic dopaminergic system and adds to growing evidence of OPFR developmental neurotoxicity. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 12, 2024

2022 journal article

Illumination angle correction during image acquisition in light-sheet fluorescence microscopy using deep learning

BIOMEDICAL OPTICS EXPRESS, 13(2), 888–901.

TL;DR: This study provides a framework that can correct the angle of the light-sheet and improve the overall image quality in high-resolution LSFM 3D image acquisition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 14, 2022

2022 journal article

Quantitative analysis of illumination and detection corrections in adaptive light sheet fluorescence microscopy

BIOMEDICAL OPTICS EXPRESS, 13(5), 2960–2974.

By: M. Rai n, C. Li n & A. Greenbaum n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 31, 2022

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