Michael Richard Vella

College of Sciences

Works (4)

Updated: April 17th, 2024 05:00

2024 article

Economic optimization of <i>Wolbachia</i>-infected <i>Aedes aegypti</i> release to prevent dengue

Hollingsworth, B. D., Cho, C., Vella, M., Roh, H., Sass, J., Lloyd, A. L., & Brown, Z. S. (2024, April 3). PEST MANAGEMENT SCIENCE, Vol. 4.

By: B. Hollingsworth  n, C. Cho n , M. Vella n, H. Roh  n, J. Sass  n, A. Lloyd n , Z. Brown n 

author keywords: Wolbachia; Aedes aegypti; optimal control
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 15, 2024

2021 journal article

Mathematical modeling of genetic pest management through female-specific lethality: Is one locus better than two?

EVOLUTIONARY APPLICATIONS, 14(6), 1612–1622.

By: M. Vella n, F. Gould n  & A. Lloyd n 

author keywords: eradication; female killing; mathematical modeling; multilocus; population genetics
TL;DR: A population genetics model with density dependence is used to evaluate the relative effectiveness of female killing approaches based on single- and two-construct arrangements and finds that the single-construct arrangement results in slightly faster population suppression, but the two- construct arrangement can eventually cause stronger suppression and cause local elimination with a smaller release size. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 5, 2021

2021 article

Rapid evolution of knockdown resistance haplotypes in response to pyrethroid selection in Aedes aegypti

Baltzegar, J., Vella, M., Gunning, C., Vasquez, G., Astete, H., Stell, F., … Gould, F. (2021, July 9). EVOLUTIONARY APPLICATIONS, Vol. 7.

By: J. Baltzegar n, M. Vella n, C. Gunning*, G. Vasquez*, H. Astete *, F. Stell*, M. Fisher*, T. Scott * ...

author keywords: Aedes aegypti; dominance; insecticide resistance; kdr; knockdown resistance; selection
TL;DR: This study describes the evolution of knockdown resistance (kdr) haplotypes in Aedes aegypti in response to pyrethroid insecticide use over the course of 18 years in Iquitos, Peru, providing evidence for the direct connection between programmatic citywidepyrethroid spraying and the increase in frequency of specific kdr haplotypes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 19, 2021

2019 journal article

Locally Fixed Alleles: A method to localize gene drive to island populations

SCIENTIFIC REPORTS, 9.

By: J. Sudweeks  n, B. Hollingsworth  n, D. Blondel n, K. Campbell, S. Dhole n, J. Eisemann*, O. Edwards *, J. Godwin n  ...

MeSH headings : Alleles; Animals; Biodiversity; Islands
TL;DR: This paper proposes the “Locally Fixed Alleles” approach as a novel means for localizing elimination by a drive to an island population that exhibits significant genetic isolation from neighboring populations and explores the feasibility and degree of localization that can be achieved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 18, 2019

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