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2024 article
Application and reduction of a nonlinear hyperelastic wall model capturing ex vivo relationships between fluid pressure, area, and wall thickness in normal and hypertensive murine left pulmonary arteries
Haider, M. A., Pearce, K. J., Chesler, N. C., Hill, N. A., & Olufsen, M. S. (2024, January 12). INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, Vol. 1.
2024 article
Characterization of differences in immune responses during bolus and continuous infusion endotoxin challenges using mathematical modelling
Windoloski, K. A., Janum, S., Berg, R. M. G., & Olufsen, M. S. (2024, March 11). EXPERIMENTAL PHYSIOLOGY.
2024 review
Guidelines for mechanistic modeling and analysis in cardiovascular research
[Review of ]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 327(2), H473–H503.
2024 journal article
SECRET: Statistical Emulation for Computational Reverse Engineering and Translation with applications in healthcare
COMPUTER METHODS IN APPLIED MECHANICS AND ENGINEERING, 430.
2024 journal article
The importance of incorporating ventricular-ventricular interaction (VVI) in the study of pulmonary hypertension
MATHEMATICAL BIOSCIENCES, 375.
2023 journal article
A topological data analysis study on murine pulmonary arterial trees with pulmonary hypertension
MATHEMATICAL BIOSCIENCES, 364.
2022 article
A computational study of aortic reconstruction in single ventricle patients
Taylor-LaPole, A. M., Colebank, M. J., Weigand, J. D., Olufsen, M. S., & Puelz, C. (2022, November 5). BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Vol. 11.
2022 article
Numerical predictions of shear stress and cyclic stretch in pulmonary hypertension due to left heart failure
Bartolo, M. A., Qureshi, M. U., Colebank, M. J., Chesler, N. C., & Olufsen, M. S. (2022, January 17). BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Vol. 1.
2022 journal article
Postural orthostatic tachycardia syndrome explained using a baroreflex response model
JOURNAL OF THE ROYAL SOCIETY INTERFACE, 19(193).
2021 journal article
A Mathematical Model of the Dynamics of Cytokine Expression and Human Immune Cell Activation in Response to the Pathogen Staphylococcus aureus
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 11.
2021 journal article
A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 321(2), H318–H338.
2021 journal article
A physiological model of the inflammatory-thermal-pain-cardiovascular interactions during an endotoxin challenge
JOURNAL OF PHYSIOLOGY-LONDON, 599(5), 1459–1485.
2021 journal article
Classification of orthostatic intolerance through data analytics
MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 59(3), 621–632.
2021 journal article
Global sensitivity analysis informed model reduction and selection applied to a Valsalva maneuver model
JOURNAL OF THEORETICAL BIOLOGY, 526.
2020 journal article
Characterization of Blood Pressure and Heart Rate Oscillations of POTS Patients via Uniform Phase Empirical Mode Decomposition
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(11), 3016–3025.
2020 journal article
Deep phenotyping of cardiac function in heart transplant patients using cardiovascular system models
JOURNAL OF PHYSIOLOGY-LONDON, 598(15), 3203–3222.
2020 journal article
Mechanistic model of hormonal contraception
PLOS COMPUTATIONAL BIOLOGY, 16(6).
2020 journal article
Persistent instability in a nonhomogeneous delay differential equation system of the Valsalva maneuver
MATHEMATICAL BIOSCIENCES, 319.
2020 journal article
Structural and hemodynamic properties of murine pulmonary arterial networks under hypoxia-induced pulmonary hypertension
PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 234(11), 1312–1329.
2019 journal article
A model-based analysis of autonomic nervous function in response to the Valsalva maneuver
JOURNAL OF APPLIED PHYSIOLOGY, 127(5), 1386–1402.
2019 journal article
Cardiovascular dynamics during head-up tilt assessed via pulsatile and non-pulsatile models
Journal of Mathematical Biology, 79(3), 987–1014.
2019 article
Control theory in biology and medicine: Introduction to the special issue
Thomas, P. J., Olufsen, M., Sepulchre, R., Iglesias, P. A., Ijspeert, A., & Srinivasan, M. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 1–6.
2019 journal article
Influence of image segmentation on one-dimensional fluid dynamics predictions in the mouse pulmonary arteries
JOURNAL OF THE ROYAL SOCIETY INTERFACE, 16(159).
2019 journal article
Sensitivity analysis and uncertainty quantification of 1-D models of pulmonary hemodynamics in mice under control and hypertensive conditions
INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 37(11).
2018 article
An optimal control approach for blood pressure regulation during head-up tilt
Williams, N. D., Mehlsen, J., Tran, H. T., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 149–159.
2018 article
Cardiovascular regulation in response to multiple hemorrhages: analysis and parameter estimation
Ciocanel, M.-V., Docken, S. S., Gasper, R. E., Dean, C., Carlson, B. E., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 105–120.
2018 journal article
Hemodynamic assessment of pulmonary hypertension in mice: a model-based analysis of the disease mechanism
Biomechanics and Modeling in Mechanobiology, 18(1), 219–243.
2018 journal article
MCMC methods for inference in a mathematical model of pulmonary circulation
Statistica Neerlandica, 72(3), 306–338.
2018 article
Parameter subset selection techniques for problems in mathematical biology
Olsen, C. H., Ottesen, J. T., Smith, R. C., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 121–138.
2018 journal article
Personalized mathematical model of endotoxin-induced inflammatory responses in young men and associated changes in heart rate variability
Mathematical Modelling of Natural Phenomena, 13(5), 42.
Ed(s): K. Maruta, S. Minaev, N. Il Kim, H. Im & V. Gubernov
2018 journal article
Practical identifiability and uncertainty quantification of a pulsatile cardiovascular model
MATHEMATICAL BIOSCIENCES, 304, 9–24.
2017 journal article
Characteristic impedance: frequency or time domain approach?
Physiological Measurement, 39(1), 014004.
2017 journal article
Increased blood pressure variability upon standing up improves reproducibility of cerebral autoregulation indices
MEDICAL ENGINEERING & PHYSICS, 47, 151–158.
2017 journal article
Integrated Inflammatory Stress (ITIS) Model
BULLETIN OF MATHEMATICAL BIOLOGY, 79(7), 1487–1509.
2017 journal article
Uncertainty Quantification in a Patient-Specific One-Dimensional Arterial Network Model: EnKF-Based Inflow Estimator
Journal of Verification, Validation and Uncertainty Quantification, 2(1), 011002.
2016 journal article
Heterogeneous mechanics of the mouse pulmonary arterial network
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 15(5), 1245–1261.
2016 journal article
Modeling the differentiation of A- and C-type baroreceptor firing patterns
JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 42(1), 11–30.
2016 journal article
Wave propagation in a 1D fluid dynamics model using pressure-area measurements from ovine arteries
Journal of Mechanics in Medicine and Biology, 16(02), 1650007.
2015 journal article
Using Kalman Filtering to Predict Time-Varying Parameters in a Model Predicting Baroreflex Regulation During Head-Up Tilt
IEEE Transactions on Biomedical Engineering, 62(8), 1992–2000.
2014 journal article
Mathematical methods and models in system biomedicine
Mathematical Biosciences, 257, 1.
2014 journal article
Modeling Cerebral Blood Flow Velocity During Orthostatic Stress
Annals of Biomedical Engineering, 43(8), 1748–1758.
2014 journal article
Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation
BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 13(5), 1137–1154.
2014 journal article
Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation
MATHEMATICAL BIOSCIENCES, 257, 50–59.
2013 journal article
Modeling the Afferent Dynamics of the Baroreflex Control System
PLoS Computational Biology, 9(12), e1003384.
Ed(s): J. Arciero
2013 journal article
Patient-specific modeling of cardiovascular and respiratory dynamics during hypercapnia
Mathematical Biosciences, 241(1), 56–74.
2013 journal article
Patient-specific modelling of head-up tilt
MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA, 31(4), 365–392.
2012 journal article
A practical approach to parameter estimation applied to model predicting heart rate regulation
JOURNAL OF MATHEMATICAL BIOLOGY, 67(1), 39–68.
2012 article
Development of Patient Specific Cardiovascular Models Predicting Dynamics in Response to Orthostatic Stress Challenges
MATHEMATICAL MODELING AND VALIDATION IN PHYSIOLOGY: APPLICATIONS TO THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS, Vol. 2064, pp. 177–213.
2012 journal article
Impaired Cerebral Autoregulation Is Associated with Brain Atrophy and Worse Functional Status in Chronic Ischemic Stroke
PLOS ONE, 7(10).
2012 journal article
Rarefaction and blood pressure in systemic and pulmonary arteries
JOURNAL OF FLUID MECHANICS, 705, 280–305.
2011 journal article
Linear and Nonlinear Viscoelastic Modeling of Aorta and Carotid Pressure-Area Dynamics Under In Vivo and Ex Vivo Conditions
ANNALS OF BIOMEDICAL ENGINEERING, 39(5), 1438–1456.
2011 journal article
PREDICTING ARTERIAL FLOW AND PRESSURE DYNAMICS USING A 1D FLUID DYNAMICS MODEL WITH A VISCOELASTIC WALL
SIAM JOURNAL ON APPLIED MATHEMATICS, 71(4), 1123–1143.
2011 conference paper
The impact of gravity during head-up tilt
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2399–2402.
2011 conference paper
Toward online, noninvasive, nonlinear assessment of cerebral autoregulation
2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2410–2413.
2010 journal article
Functionality of the baroreceptor nerves in heart rate regulation
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 101(2), 208–219.
2010 article
Linear and Nonlinear Viscoelastic Modeling of Ovine Aortic Biomechanical Properties under in vivo and ex vivo Conditions
2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), pp. 2634–2637.
2009 journal article
ESTIMATION AND IDENTIFICATION OF PARAMETERS IN A LUMPED CEREBROVASCULAR MODEL
MATHEMATICAL BIOSCIENCES AND ENGINEERING, 6(1), 93–115.
2009 journal article
Viscoelastic models for passive arterial wall dynamics
Advances in Applied Mathematics & Mechanics, 1(2), 151–165.
2008 journal article
Analysis of Viscoelastic Wall Properties in Ovine Arteries
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 56(2), 210–219.
2008 journal article
BLOOD FLOW IN THE CIRCLE OF WILLIS: MODELING AND CALIBRATION
MULTISCALE MODELING & SIMULATION, 7(2), 888–909.
2008 article
Introduction to the special issues: Short-term cardiovascular-respiratory control mechanisms
Batzel, J. J., Novak, V., Kappel, F., Olufsen, M. S., & Tran, H. T. (2008, March). CARDIOVASCULAR ENGINEERING, Vol. 8, pp. 1–4.
2008 journal article
Mathematical Modelling of the Systemic Circulation: investigating pressure and flow throughout the microcirculation
Artery Research, 2(3), 112.
2008 journal article
Modeling heart rate regulation - Part II: Parameter identification and analysis
CARDIOVASCULAR ENGINEERING, 8(2), 109–119.
2007 journal article
Fractal network model for simulating abdominal and lower extremity blood flow during resting and exercise conditions
Computer Methods in Biomechanics and Biomedical Engineering, 10(1), 39–51.
2007 journal article
Modeling heart rate regulation - Part I: Sit-to-stand versus head-up tilt
CARDIOVASCULAR ENGINEERING, 8(2), 73–87.
2007 journal article
Sensitivity analysis and model assessment: Mathematical models for arterial blood flow and blood pressure
CARDIOVASCULAR ENGINEERING, 8(2), 94–108.
2007 journal article
Stochastic and deterministic models for agricultural production networks
Mathematical Biosciences and Engineering, 4(3), 373–402.
Contributors: P. Bai*, H. Banks*, S. Dediu*, A. Govan, M. Last, A. Lloyd* , H. Nguyen*, *, G. Rempala, B. Slenning*
2007 journal article
The Disparate Effects of Microvascular Rarefaction and Reduced Compliance on Proximal Haemodynamics: Investigation with a Mathematical and Computational Model of the Circulation
Artery Research, 1(2), 74.
2006 journal article
Analysis of blood flow velocity and pressure signals using the multipulse method
Mathematical Biosciences and Engineering, 3(2), 419–440.
2006 chapter
Cardiovascular modeling at IMFUFA, in The way through science and philosophy
In H. B. Andersen, F. V. Christiansen, K. F. Jorgensen, & V. F. Hendricks (Eds.), Tributes (Vol. 4, pp. 87–96). London: College Publications.
Ed(s): H. Andersen, F. Christiansen, K. Jorgensen & V. Hendricks
2006 journal article
Modeling baroreflex regulation of heart rate during orthostatic stress
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 291(5), R1355–R1368.
2005 journal article
Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation
JOURNAL OF APPLIED PHYSIOLOGY, 99(4), 1523–1537.
2004 book
Applied Mathematical Models in Human Physiology
2004 journal article
Modeling Cerebral Blood Flow Control During Posture Change from Sitting to Standing
Cardiovascular Engineering, 4(1), 47–58.
2004 journal article
On deriving lumped models for blood flow and pressure in the systemic arteries
MATHEMATICAL BIOSCIENCES AND ENGINEERING, 1(1), 61–80.
2003 journal article
New roles for the gamma rhythm: Population tuning and preprocessing for the beta rhythm
JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 14(1), 33–54.
2002 journal article
Dynamics of cerebral blood flow regulation explained using a lumped parameter model
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 282(2), R611–R622.
2001 chapter
A One-Dimensional Fluid Dynamic Model of the Systemic Arteries
In Computational Modeling in Biological Fluid Dynamics (pp. 167–187).
2001 journal article
A lumped parameter model for cerebral blood flow regulation
Advances in Bioengineering, 51, 277–278.
2000 chapter
A one-dimensional fluid dynamic model of the systemic arteries
In J. T. Ottesen & M. Danielsen (Eds.), Mathematical modelling in medicine (pp. 79–97).
Ed(s): J. Ottesen & M. Danielsen
2000 journal article
Numerical Simulation and Experimental Validation of Blood Flow in Arteries with Structured-Tree Outflow Conditions
Annals of Biomedical Engineering, 28(11), 1281–1299.
1999 journal article
Structured tree outflow condition for blood flow in larger systemic arteries
American Journal of Physiology-Heart and Circulatory Physiology, 276(1), H257–H268.
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