Mette Olufsen

A computational study of aortic reconstruction in single ventricle patients

Taylor-LaPole, A. M., Colebank, M. J., Weigand, J. D., Olufsen, M. S., & Puelz, C. (2022, November 5). BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Vol. 11.

Numerical predictions of shear stress and cyclic stretch in pulmonary hypertension due to left heart failure

Bartolo, M. A., Qureshi, M. U., Colebank, M. J., Chesler, N. C., & Olufsen, M. S. (2022, January 17). BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, Vol. 1.

Postural orthostatic tachycardia syndrome explained using a baroreflex response model

JOURNAL OF THE ROYAL SOCIETY INTERFACE, 19(193).

A Mathematical Model of the Dynamics of Cytokine Expression and Human Immune Cell Activation in Response to the Pathogen Staphylococcus aureus

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 11.

A multiscale model of vascular function in chronic thromboembolic pulmonary hypertension

AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 321(2), H318–H338.

A physiological model of the inflammatory-thermal-pain-cardiovascular interactions during an endotoxin challenge

JOURNAL OF PHYSIOLOGY-LONDON, 599(5), 1459–1485.

Classification of orthostatic intolerance through data analytics

MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, 59(3), 621–632.

Global sensitivity analysis informed model reduction and selection applied to a Valsalva maneuver model

JOURNAL OF THEORETICAL BIOLOGY, 526.

Sensitivity analysis and uncertainty quantification of 1-D models of pulmonary hemodynamics in mice under control and hypertensive conditions

INTERNATIONAL JOURNAL FOR NUMERICAL METHODS IN BIOMEDICAL ENGINEERING, 37(11).

Characterization of Blood Pressure and Heart Rate Oscillations of POTS Patients via Uniform Phase Empirical Mode Decomposition

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(11), 3016–3025.

Deep phenotyping of cardiac function in heart transplant patients using cardiovascular system models

JOURNAL OF PHYSIOLOGY-LONDON, 598(15), 3203–3222.

Mechanistic model of hormonal contraception

PLOS COMPUTATIONAL BIOLOGY, 16(6).

Persistent instability in a nonhomogeneous delay differential equation system of the Valsalva maneuver

MATHEMATICAL BIOSCIENCES, 319.

Structural and hemodynamic properties of murine pulmonary arterial networks under hypoxia-induced pulmonary hypertension

PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART H-JOURNAL OF ENGINEERING IN MEDICINE, 234(11), 1312–1329.

A model-based analysis of autonomic nervous function in response to the Valsalva maneuver

JOURNAL OF APPLIED PHYSIOLOGY, 127(5), 1386–1402.

An optimal control approach for blood pressure regulation during head-up tilt

Williams, N. D., Mehlsen, J., Tran, H. T., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 149–159.

Cardiovascular dynamics during head-up tilt assessed via pulsatile and non-pulsatile models

Journal of Mathematical Biology, 79(3), 987–1014.

Cardiovascular regulation in response to multiple hemorrhages: analysis and parameter estimation

Ciocanel, M.-V., Docken, S. S., Gasper, R. E., Dean, C., Carlson, B. E., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 105–120.

Control theory in biology and medicine: Introduction to the special issue

Thomas, P. J., Olufsen, M., Sepulchre, R., Iglesias, P. A., Ijspeert, A., & Srinivasan, M. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 1–6.

Influence of image segmentation on one-dimensional fluid dynamics predictions in the mouse pulmonary arteries

JOURNAL OF THE ROYAL SOCIETY INTERFACE, 16(159).

Parameter subset selection techniques for problems in mathematical biology

Olsen, C. H., Ottesen, J. T., Smith, R. C., & Olufsen, M. S. (2019, April). BIOLOGICAL CYBERNETICS, Vol. 113, pp. 121–138.

Characteristic impedance: frequency or time domain approach?

Physiological Measurement, 39(1), 014004.

Hemodynamic assessment of pulmonary hypertension in mice: a model-based analysis of the disease mechanism

Biomechanics and Modeling in Mechanobiology, 18(1), 219–243.

MCMC methods for inference in a mathematical model of pulmonary circulation

Statistica Neerlandica, 72(3), 306–338.

Personalized mathematical model of endotoxin-induced inflammatory responses in young men and associated changes in heart rate variability

Mathematical Modelling of Natural Phenomena, 13(5), 42.

Practical identifiability and uncertainty quantification of a pulsatile cardiovascular model

MATHEMATICAL BIOSCIENCES, 304, 9–24.

Increased blood pressure variability upon standing up improves reproducibility of cerebral autoregulation indices

MEDICAL ENGINEERING & PHYSICS, 47, 151–158.

Integrated Inflammatory Stress (ITIS) Model

BULLETIN OF MATHEMATICAL BIOLOGY, 79(7), 1487–1509.

Modeling the differentiation of A- and C-type baroreceptor firing patterns

JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 42(1), 11–30.

Uncertainty Quantification in a Patient-Specific One-Dimensional Arterial Network Model: EnKF-Based Inflow Estimator

Journal of Verification, Validation and Uncertainty Quantification, 2(1), 011002.

Heterogeneous mechanics of the mouse pulmonary arterial network

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 15(5), 1245–1261.

Wave propagation in a 1D fluid dynamics model using pressure-area measurements from ovine arteries

Journal of Mechanics in Medicine and Biology, 16(02), 1650007.

Using Kalman Filtering to Predict Time-Varying Parameters in a Model Predicting Baroreflex Regulation During Head-Up Tilt

IEEE Transactions on Biomedical Engineering, 62(8), 1992–2000.

Mathematical methods and models in system biomedicine

Mathematical Biosciences, 257, 1.

Modeling Cerebral Blood Flow Velocity During Orthostatic Stress

Annals of Biomedical Engineering, 43(8), 1748–1758.

Numerical simulation of blood flow and pressure drop in the pulmonary arterial and venous circulation

BIOMECHANICS AND MODELING IN MECHANOBIOLOGY, 13(5), 1137–1154.

Patient-specific modelling of head-up tilt

MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA, 31(4), 365–392.

Structural correlation method for model reduction and practical estimation of patient specific parameters illustrated on heart rate regulation

MATHEMATICAL BIOSCIENCES, 257, 50–59.

A practical approach to parameter estimation applied to model predicting heart rate regulation

JOURNAL OF MATHEMATICAL BIOLOGY, 67(1), 39–68.

Development of Patient Specific Cardiovascular Models Predicting Dynamics in Response to Orthostatic Stress Challenges

MATHEMATICAL MODELING AND VALIDATION IN PHYSIOLOGY: APPLICATIONS TO THE CARDIOVASCULAR AND RESPIRATORY SYSTEMS, Vol. 2064, pp. 177–213.

Modeling the Afferent Dynamics of the Baroreflex Control System

PLoS Computational Biology, 9(12), e1003384.

Patient-specific modeling of cardiovascular and respiratory dynamics during hypercapnia

Mathematical Biosciences, 241(1), 56–74.

Impaired Cerebral Autoregulation Is Associated with Brain Atrophy and Worse Functional Status in Chronic Ischemic Stroke

PLOS ONE, 7(10).

Rarefaction and blood pressure in systemic and pulmonary arteries

JOURNAL OF FLUID MECHANICS, 705, 280–305.

Functionality of the baroreceptor nerves in heart rate regulation

COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 101(2), 208–219.

Linear and Nonlinear Viscoelastic Modeling of Aorta and Carotid Pressure-Area Dynamics Under In Vivo and Ex Vivo Conditions

ANNALS OF BIOMEDICAL ENGINEERING, 39(5), 1438–1456.

PREDICTING ARTERIAL FLOW AND PRESSURE DYNAMICS USING A 1D FLUID DYNAMICS MODEL WITH A VISCOELASTIC WALL

SIAM JOURNAL ON APPLIED MATHEMATICS, 71(4), 1123–1143.

The impact of gravity during head-up tilt

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2399–2402.

Toward online, noninvasive, nonlinear assessment of cerebral autoregulation

2011 Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC), 2410–2413.

Linear and Nonlinear Viscoelastic Modeling of Ovine Aortic Biomechanical Properties under in vivo and ex vivo Conditions

2010 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), pp. 2634–2637.

Analysis of Viscoelastic Wall Properties in Ovine Arteries

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 56(2), 210–219.

ESTIMATION AND IDENTIFICATION OF PARAMETERS IN A LUMPED CEREBROVASCULAR MODEL

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 6(1), 93–115.

Viscoelastic models for passive arterial wall dynamics

Advances in Applied Mathematics & Mechanics, 1(2), 151–165.

BLOOD FLOW IN THE CIRCLE OF WILLIS: MODELING AND CALIBRATION

MULTISCALE MODELING & SIMULATION, 7(2), 888–909.

Introduction to the special issues: Short-term cardiovascular-respiratory control mechanisms

Batzel, J. J., Novak, V., Kappel, F., Olufsen, M. S., & Tran, H. T. (2008, March). CARDIOVASCULAR ENGINEERING, Vol. 8, pp. 1–4.

Mathematical Modelling of the Systemic Circulation: investigating pressure and flow throughout the microcirculation

Artery Research, 2(3), 112.

Modeling heart rate regulation - Part I: Sit-to-stand versus head-up tilt

CARDIOVASCULAR ENGINEERING, 8(2), 73–87.

Modeling heart rate regulation - Part II: Parameter identification and analysis

CARDIOVASCULAR ENGINEERING, 8(2), 109–119.

Sensitivity analysis and model assessment: Mathematical models for arterial blood flow and blood pressure

CARDIOVASCULAR ENGINEERING, 8(2), 94–108.

Fractal network model for simulating abdominal and lower extremity blood flow during resting and exercise conditions

Computer Methods in Biomechanics and Biomedical Engineering, 10(1), 39–51.

Stochastic and deterministic models for agricultural production networks

Mathematical Biosciences and Engineering, 4(3), 373–402.

The Disparate Effects of Microvascular Rarefaction and Reduced Compliance on Proximal Haemodynamics: Investigation with a Mathematical and Computational Model of the Circulation

Artery Research, 1(2), 74.

Analysis of blood flow velocity and pressure signals using the multipulse method

Mathematical Biosciences and Engineering, 3(2), 419–440.

Cardiovascular modeling at IMFUFA, in The way through science and philosophy

In H. B. Andersen, F. V. Christiansen, K. F. Jorgensen, & V. F. Hendricks (Eds.), Tributes (Vol. 4, pp. 87–96). London: College Publications.

Modeling baroreflex regulation of heart rate during orthostatic stress

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 291(5), R1355–R1368.

Blood pressure and blood flow variation during postural change from sitting to standing: model development and validation

JOURNAL OF APPLIED PHYSIOLOGY, 99(4), 1523–1537.

Applied Mathematical Models in Human Physiology

Modeling Cerebral Blood Flow Control During Posture Change from Sitting to Standing

Cardiovascular Engineering, 4(1), 47–58.

On deriving lumped models for blood flow and pressure in the systemic arteries

MATHEMATICAL BIOSCIENCES AND ENGINEERING, 1(1), 61–80.

New roles for the gamma rhythm: Population tuning and preprocessing for the beta rhythm

JOURNAL OF COMPUTATIONAL NEUROSCIENCE, 14(1), 33–54.

Dynamics of cerebral blood flow regulation explained using a lumped parameter model

AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY, 282(2), R611–R622.

A One-Dimensional Fluid Dynamic Model of the Systemic Arteries

In Computational Modeling in Biological Fluid Dynamics (pp. 167–187).

A lumped parameter model for cerebral blood flow regulation

Advances in Bioengineering, 51, 277–278.

A one-dimensional fluid dynamic model of the systemic arteries

In J. T. Ottesen & M. Danielsen (Eds.), Mathematical modelling in medicine (pp. 79–97).

Numerical Simulation and Experimental Validation of Blood Flow in Arteries with Structured-Tree Outflow Conditions

Annals of Biomedical Engineering, 28(11), 1281–1299.

Structured tree outflow condition for blood flow in larger systemic arteries

American Journal of Physiology-Heart and Circulatory Physiology, 276(1), H257–H268.