Michael Taylor Hensley
Works (21)
Updated: July 5th, 2023 15:42
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
www.nature.com (publisher PDF)
Sources: Web Of Science, ORCID
Added: March 23, 2020
2018 journal article
Cardiac cell-integrated microneedle patch for treating myocardial infarction
SCIENCE ADVANCES, 4(11).
MeSH headings : Animals; Cells, Cultured; Microtechnology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Needles; Rats; Rats, Inbred WKY; Regeneration; Stromal Cells / cytology; Stromal Cells / transplantation; Swine; Tissue Engineering / instrumentation
Sources: Web Of Science, ORCID
Added: December 31, 2018
2018 journal article
Targeted repair of heart injury by stem cells fused with platelet nanovesicles
NATURE BIOMEDICAL ENGINEERING, 2(1), 17–26.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Targeting regenerative exosomes to myocardial infarction using cardiac homing peptide
THERANOSTICS, 8(7), 1869–1878.
author keywords: Targeting; exosomes; cardiac regeneration; heart disease; myocardial infarction
MeSH headings : Administration, Intravenous; Animals; Biological Products / administration & dosage; Biological Products / pharmacokinetics; Biological Therapy / methods; Cell Survival; Disease Models, Animal; Echocardiography; Exosomes; Molecular Targeted Therapy / methods; Myocardial Infarction / therapy; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / physiology; Peptides / administration & dosage; Peptides / pharmacokinetics; Rats; Treatment Outcome
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
A Regenerative Cardiac Patch Formed by Spray Painting of Biomaterials onto the Heart
Tissue Engineering Part C: Methods, 23(3), 146–155.
author keywords: cardiac patch; platelet fibrin gel; myocardial infarction; regeneration
MeSH headings : Animals; Biocompatible Materials / chemistry; Blood Platelets / metabolism; Fibrin / metabolism; Heart / physiology; Male; Mice; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Paintings; Rats; Rats, Sprague-Dawley; Regeneration / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Derivation of therapeutic lung spheroid cells from minimally invasive transbronchial pulmonary biopsies
Respiratory Research, 18(1).
author keywords: Pulmonary progenitor cells; Lung spheroid; Stem cell
MeSH headings : Adolescent; Aged; Animals; Biopsy; Bronchi / cytology; Bronchi / physiology; Cell Culture Techniques / methods; Female; Human Umbilical Vein Endothelial Cells / physiology; Humans; Infusions, Intravenous; Lung / cytology; Lung / physiology; Male; Mice; Mice, Nude; Middle Aged; Spheroids, Cellular / physiology; Stem Cell Transplantation / methods; Stem Cells / physiology
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Heart Repair Using Nanogel-Encapsulated Human Cardiac Stem Cells in Mice and Pigs with Myocardial Infarction
ACS NANO, 11(10), 9738–9749.
author keywords: cardiac stem cells; nanogel; myocardial infarction; biomaterials; mouse model; pig model
MeSH headings : Acrylamides / chemistry; Acrylates / chemistry; Animals; Disease Models, Animal; Female; Humans; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Nanogels; Particle Size; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Surface Properties; Swine; Temperature
Source: Web Of Science
Added: August 6, 2018
2017 journal article
Intracoronary allogeneic cardiosphere-derived stem cells are safe for use in dogs with dilated cardiomyopathy
Journal of Cellular and Molecular Medicine, 21(8), 1503–1512.
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy; allogeneic
MeSH headings : Animals; Biomarkers / metabolism; Cardiomyopathy, Dilated / diagnostic imaging; Cardiomyopathy, Dilated / immunology; Cardiomyopathy, Dilated / pathology; Cardiomyopathy, Dilated / therapy; Coronary Vessels / cytology; Coronary Vessels / immunology; Dogs; Echocardiography; Endoglin / genetics; Endoglin / immunology; Female; Gene Expression; Humans; Male; Myocardium / immunology; Myocardium / pathology; Proto-Oncogene Proteins c-kit / genetics; Proto-Oncogene Proteins c-kit / immunology; Spheroids, Cellular / cytology; Spheroids, Cellular / immunology; Spheroids, Cellular / transplantation; Stem Cell Transplantation; Stem Cells / cytology; Stem Cells / immunology; Thy-1 Antigens / genetics; Thy-1 Antigens / immunology; Transplantation, Homologous
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2017 journal article
Safety and Efficacy of Allogeneic Lung Spheroid Cells in a Mismatched Rat Model of Pulmonary Fibrosis
STEM CELLS Translational Medicine, 6(10), 1905–1916.
author keywords: Fibrosis; Pulmonary; Syngeneic; Allogeneic; Stem cells
MeSH headings : Animals; Bleomycin / toxicity; Cells, Cultured; Female; Lung / cytology; Pulmonary Fibrosis / etiology; Pulmonary Fibrosis / therapy; Rats; Rats, Wistar; Spheroids, Cellular / transplantation; Stem Cell Transplantation / adverse effects; Stem Cell Transplantation / methods; Transplantation, Homologous / adverse effects; Transplantation, Homologous / methods
Sources: Web Of Science, Crossref
Added: August 6, 2018
2017 journal article
Therapeutic microparticles functionalized with biomimetic cardiac stem cell membranes and secretome
Nature Communications, 8(1).
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / metabolism; Biomimetic Materials / pharmacology; Cell Fractionation; Cell Membrane / chemistry; Cell Membrane / metabolism; Cell Membrane / transplantation; Cell-Derived Microparticles / chemistry; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Culture Media, Conditioned / chemistry; Culture Media, Conditioned / isolation & purification; Disease Models, Animal; Gene Expression; Hepatocyte Growth Factor / genetics; Hepatocyte Growth Factor / metabolism; Humans; Injections, Intralesional; Insulin-Like Growth Factor I / genetics; Insulin-Like Growth Factor I / metabolism; Intercellular Signaling Peptides and Proteins / pharmacology; Male; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocardium / metabolism; Myocardium / pathology; Paracrine Communication; Recovery of Function / drug effects; Stem Cells / cytology; Stem Cells / metabolism; Vascular Endothelial Growth Factor A / genetics; Vascular Endothelial Growth Factor A / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Angiopellosis as an Alternative Mechanism of Cell Extravasation
STEM CELLS, 35(1), 170–180.
author keywords: Extravasation; Angiopellosis; Transmigration; Stem cell infusion; Diapedesis
MeSH headings : Animals; Blood Vessels / physiology; CD11 Antigens / metabolism; Cell Aggregation; Cell Membrane / metabolism; Cell Shape; Dogs; Extravasation of Diagnostic and Therapeutic Materials / pathology; Female; Humans; Injections; Intravital Microscopy; Male; Mesenchymal Stem Cells; Microspheres; Myocytes, Cardiac / cytology; Polymers / chemistry; Rats; Time Factors; Transendothelial and Transepithelial Migration; Zebrafish / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Effects of Matrix Metalloproteinases on the Performance of Platelet Fibrin Gel Spiked With Cardiac Stem Cells in Heart Repair
STEM CELLS TRANSLATIONAL MEDICINE, 5(6), 793–803.
author keywords: Cardiac stem cells; Platelet fibrin gel; Matrix metalloproteinases; Heart repair
MeSH headings : Animals; Blood Platelets / metabolism; Dipeptides / administration & dosage; Disease Models, Animal; Echocardiography; Fibrin / administration & dosage; Humans; Matrix Metalloproteinase Inhibitors / administration & dosage; Matrix Metalloproteinases / metabolism; Myocardial Infarction / enzymology; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / metabolism; Rats; Regeneration / drug effects; Stem Cell Transplantation
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Cardiac regenerative potential of cardiosphere-derived cells from adult dog hearts
Journal of Cellular and Molecular Medicine, 19(8), 1805–1813.
author keywords: cardiosphere-derived cells; dogs; dilated cardiomyopathy; stem cell therapy
MeSH headings : Aging; Animals; Apoptosis; Cell Differentiation; Cells, Cultured; Dogs; Female; Fibrosis; Heart / physiology; Heart Function Tests; Mice, SCID; Myocardium / pathology; Myocytes, Cardiac / cytology; Neovascularization, Physiologic; Paracrine Communication; Regeneration; Spheroids, Cellular / cytology
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018
2015 chapter
Cryopreservation of Neonatal Cardiomyocytes
In Methods in Molecular Biology (Vol. 1299, pp. 153–160).
author keywords: Cardiomyocytes; Cryopreservation; Cardiac research
MeSH headings : Animals; Animals, Newborn; Cell Culture Techniques; Cells, Cultured; Cryopreservation / methods; Myocytes, Cardiac / cytology; Rats
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Intravenous Cardiac Stem Cell-Derived Exosomes Ameliorate Cardiac Dysfunction in Doxorubicin Induced Dilated Cardiomyopathy
Stem Cells International, 2015, 1–8.
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Isolation and Cryopreservation of Neonatal Rat Cardiomyocytes
Journal of Visualized Experiments, (98).
author keywords: Developmental Biology; Issue 98; Cryopreservation; Cardiomyocytes; Cell-based Assay; Cell Culture; Cardiac Research; In Vitro Assay
MeSH headings : Actinin / analysis; Actinin / metabolism; Animals; Animals, Newborn; Cell Culture Techniques; Cell Separation / methods; Cell Survival / physiology; Cryopreservation / methods; Cryoprotective Agents / chemistry; Dimethyl Sulfoxide / chemistry; Freezing; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Rats; Sarcomeres / chemistry; Sarcomeres / metabolism
Sources: Web Of Science, Crossref
Added: August 6, 2018
2015 journal article
Rapid and Efficient Production of Coronary Artery Ligation and Myocardial Infarction in Mice Using Surgical Clips
PLOS ONE, 10(11).
MeSH headings : Animals; Coronary Vessels / surgery; Disease Models, Animal; Ligation; Mice; Myocardial Infarction / etiology; Myocardial Infarction / mortality; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Surgical Instruments; Suture Techniques; Vascular Surgical Procedures
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Magnetic antibody-linked nanomatchmakers for therapeutic cell targeting
Nature Communications, 5(1).
MeSH headings : Animals; Antibodies; Bone Marrow Cells / metabolism; Bone Marrow Transplantation / methods; Cell Movement; Ferrosoferric Oxide / therapeutic use; Iron; Leukocytes, Mononuclear / metabolism; Magnets; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Nanotechnology / methods; Rats; Regeneration; Stem Cells
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
Magnetic targeting of cardiosphere-derived stem cells with ferumoxytol nanoparticles for treating rats with myocardial infarction
BIOMATERIALS, 35(30), 8528–8539.
author keywords: Cardiac stem cells; Magnetic targeting; Myocardial infarction; Ferumoxytol; MRI; Superparamagnetic iron oxide nanoparticles
MeSH headings : Animals; Apoptosis / drug effects; Cell Movement / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Female; Ferrosoferric Oxide / pharmacology; Ferrosoferric Oxide / therapeutic use; Finite Element Analysis; Heart Function Tests; Heparin / pharmacology; Humans; Inflammation / pathology; Iron Overload / pathology; Magnetic Phenomena; Male; Myocardial Infarction / pathology; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocardium / pathology; Nanoparticles / therapeutic use; Nanoparticles / ultrastructure; Neovascularization, Physiologic / drug effects; Protamines / pharmacology; Rats; Rats, Inbred WKY; Spheroids, Cellular / drug effects; Spheroids, Cellular / pathology
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Relative Roles of CD90 and c-Kit to the Regenerative Efficacy of Cardiosphere-Derived Cells in Humans and in a Mouse Model of Myocardial Infarction
JOURNAL OF THE AMERICAN HEART ASSOCIATION, 3(5).
author keywords: cardiosphere-derived cells; CD90; ckit; myocardial infarction
MeSH headings : Analysis of Variance; Animals; Apoptosis / physiology; Biomarkers / analysis; Cell Differentiation / physiology; Cell Transplantation / methods; Cells, Cultured; Disease Models, Animal; Heart Function Tests; Humans; Male; Mice; Mice, SCID; Myocardial Infarction / physiopathology; Myocardial Infarction / therapy; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / transplantation; Prospective Studies; Proto-Oncogene Proteins c-kit / metabolism; Regeneration / physiology; Role; Sensitivity and Specificity; Thy-1 Antigens / metabolism; Treatment Outcome
Source: Web Of Science
Added: August 6, 2018
