@article{schneider_ames_dicicco_savage_atkins_wood_gookin_2015, title={Recovery of normal esophageal function in a kitten with diffuse megaesophagus and an occult lower esophageal stricture}, volume={17}, ISSN={["1532-2750"]}, DOI={10.1177/1098612x14542451}, abstractNote={ An 8-week-old male domestic shorthair was presented to the Internal Medicine Service at North Carolina State University for regurgitation. Radiographic diagnosis of generalized esophageal dilation and failure of esophageal peristalsis were compatible with diagnosis of congenital megaesophagus. Endoscopic examination of the esophagus revealed a fibrous stricture just orad to the lower esophageal sphincter. Conservative management to increase the body condition and size of the kitten consisted of feeding through a gastrostomy tube, during which time the esophagus regained normal peristaltic function, the stricture orifice widened in size and successful balloon dilatation of the stricture was performed. Esophageal endoscopy should be considered to rule out a stricture near the lower esophageal sphincter in kittens with radiographic findings suggestive of congenital megaesophagus. Management of such kittens by means of gastrostomy tube feeding may be associated with a return of normal esophageal motility and widening of the esophageal stricture, and facilitate subsequent success of interventional dilation of the esophageal stricture. }, number={6}, journal={JOURNAL OF FELINE MEDICINE AND SURGERY}, author={Schneider, Jaycie and Ames, Marisa and DiCicco, Michael and Savage, Mason and Atkins, Clarke and Wood, Michael and Gookin, Jody L.}, year={2015}, month={Jun}, pages={557–561} } @article{hutchins_vaden_jacob_harris_bowles_wood_bailey_2014, title={Vaginal Microbiota of Spayed Dogs with or without Recurrent Urinary Tract Infections}, volume={28}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.12299}, abstractNote={BackgroundLimited information is available regarding the vaginal microbiota of normal spayed dogs and spayed dogs with recurrent UTIs. Vaginal lactic acid‐producing bacteria (LAB) have been associated with decreased frequency of recurrent urinary tract infection in women and may have a protective role within the urinary tract of female dogs.}, number={2}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Hutchins, R. G. and Vaden, S. L. and Jacob, M. E. and Harris, T. L. and Bowles, K. D. and Wood, M. W. and Bailey, C. S.}, year={2014}, month={Mar}, pages={300–304} } @article{hutchins_bailey_jacob_harris_wood_saker_vaden_2013, title={The Effect of an Oral Probiotic Containing Lactobacillus, Bifidobacterium, and Bacillus Species on the Vaginal Microbiota of Spayed Female Dogs}, volume={27}, ISSN={["1939-1676"]}, DOI={10.1111/jvim.12174}, abstractNote={BackgroundRecurrent urinary tract infections (UTIs) are often difficult to treat. Vaginal colonization with lactic acid‐producing bacteria (LAB) is associated with reduced frequency of recurrent UTIs in women. Oral probiotics might help increase the prevalence of vaginal LAB and decrease the frequency of recurrent UTIs in dogs.}, number={6}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Hutchins, R. G. and Bailey, C. S. and Jacob, M. E. and Harris, T. L. and Wood, M. W. and Saker, K. E. and Vaden, S. L.}, year={2013}, month={Nov}, pages={1368–1371} } @article{wood_nordone_vaden_breitschwerdt_2011, title={Assessment of urine solute and matrix effects on the performance of an enzyme-linked immunosorbent assay for measurement of interleukin-6 in dog urine}, volume={23}, ISSN={["1040-6387"]}, DOI={10.1177/104063871102300219}, abstractNote={Measurement of cytokine concentrations within body fluids is a means of recognizing subclinical and/or unresolved, infectious and inflammatory states in patients. In the urinary tract, such information may be useful for identifying patients with pyelonephritis, asymptomatic bacteriuria, recurrent infections, and cystitis. One such cytokine, interleukin-6 (IL-6), is recognized as a primary cytokine that is produced following exposure of the urothelium to bacterial virulence factors. Complicating reliable testing for this and other cytokines is the nature of urine itself. Urine varies widely in its composition as indicated by the range of pH and urine specific gravity (USG) observed in healthy patients. An additional variable is the protein and carbohydrate matrix capable of hindering immunologic testing modalities, such as enzyme-linked immunosorbent assays (ELISAs). The purpose of the current study was to examine the role of urine pH, USG, and matrix while optimizing a canine-specific chemiluminescent ELISA for the measurement of IL-6 in the urine of dogs. Urine spiked with IL-6 obtained maximal IL-6 quantitative recoveries of only 55 ± 10% (mean ± 1 standard deviation) when an ELISA optimized for cell culture supernatants was used. The urine matrix and variations in USG were determined to by contributing to this poor IL-6 recovery. Using specific matrix inhibitors and optimal dilutions improved the IL-6 quantitative recovery to 91 ± 5%. Urine pH (5.5–9.5) had no effect. The current work underscores the importance of critically optimizing testing modalities for biomarkers, particularly if they are immunologic in origin.}, number={2}, journal={JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION}, author={Wood, Michael W. and Nordone, Sushila K. and Vaden, Shelly L. and Breitschwerdt, Edward B.}, year={2011}, month={Mar}, pages={316–320} } @article{minter_wood_hill_lewbart_2010, title={CYSTOSCOPIC GUIDED REMOVAL OF ECTOPIC EGGS FROM THE URINARY BLADDER OF THE FLORIDA COOTER TURTLE (PSEUDEMYS FLORIDANA FLORIDANA)}, volume={41}, ISSN={["1042-7260"]}, DOI={10.1638/2009-0196.1}, abstractNote={Abstract Three gravid, female, wild Florida cooter turtles (Pseudemys floridana floridana) were evaluated and treated by the North Carolina State University College of Veterinary Medicine Turtle Rescue Team as a result of traumatic injuries or infection. As part of medical management, oviposition was induced using oxytocin, which was only partially effective. In all three cases, ectopic eggs were subsequently identified in the urinary bladder by ultrasound and were successfully removed via a minimally invasive cystoscopic-guided technique. One of the three turtles died within several days of the procedure, and necropsy revealed granulomatous bacterial cystitis. It is hypothesized that these complications were likely due to the length of time between induction with oxytocin and the identification and removal of the ectopic egg.}, number={3}, journal={JOURNAL OF ZOO AND WILDLIFE MEDICINE}, author={Minter, Larry J. and Wood, Michael W. and Hill, Tracy L. and Lewbart, Gregory A.}, year={2010}, month={Sep}, pages={503–509} } @article{diniz_wood_maggi_sontakke_stepnik_breitschwerdt_2009, title={Co-isolation of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs}, volume={138}, ISSN={0378-1135}, url={http://dx.doi.org/10.1016/j.vetmic.2009.01.038}, DOI={10.1016/j.vetmic.2009.01.038}, abstractNote={This report describes the clinical presentation, isolation and treatment of two dogs naturally infected with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii. Chronic and progressive polyarthritis was the primary complaint for dog #1, from which B. henselae and B. vinsonii subsp. berkhoffii were cultured on three independent occasions from blood and joint fluid samples, despite administration of nearly 4 months of non-consecutive antibiotic therapy. A clinically atypical and progressively severe trauma-associated seroma was the primary complaint for dog #2, from which B. henselae and B. vinsonii subsp. berkhoffii were isolated from serum, blood and seroma fluid. Dogs can be co-infected with two Bartonella spp. and infection with these organisms should not be ruled out if specific antibodies are not detected. Specialized culture techniques should be used for isolation and to assess antibiotic efficacy.}, number={3-4}, journal={Veterinary Microbiology}, publisher={Elsevier BV}, author={Diniz, Pedro Paulo Vissotto de Paiva and Wood, Michael and Maggi, Ricardo G. and Sontakke, Sushama and Stepnik, Matt and Breitschwerdt, Edward B.}, year={2009}, month={Sep}, pages={368–372} } @article{wood_vaden_cerda-gonzalez_keene_2007, title={Cystoscopic-guided balloon dilation of a urethral stricture in a female dog}, volume={48}, number={7}, journal={Canadian Veterinary Journal}, author={Wood, M. W. and Vaden, S. and Cerda-Gonzalez, S. and Keene, B.}, year={2007}, pages={731–733} }