Michael Khan

Works (7)

Updated: April 5th, 2024 15:34

2023 journal article

A novel task of canine olfaction for use in adult and senior pet dogs

SCIENTIFIC REPORTS, 13(1).

By: M. Khan n, A. Mondino n, K. Russell n, B. Case n, G. Fefer n, H. Woods n, N. Olby n, M. Gruen n

MeSH headings : Dogs; Animals; Smell; Food; Aging; Neuropsychological Tests
TL;DR: A novel olfaction test using spontaneous search behavior in dogs to find a hidden food treat in a three-choice task with both light-phase and dark-phase conditions is described, making it feasible to compare between and within groups of pet dogs. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 19, 2023

2023 journal article

Activity patterns are associated with fractional lifespan, memory, and gait speed in aged dogs

SCIENTIFIC REPORTS, 13(1).

By: A. Mondino n, M. Khan n, B. Case n, S. Giovagnoli*, A. Thomson n, B. Lascelles n, M. Gruen n, N. Olby n

MeSH headings : Humans; Dogs; Animals; Alzheimer Disease; Longevity; Walking Speed; Gait; Cognition; Cognitive Dysfunction; Aging / psychology; Pain
TL;DR: It is found that activity patterns in dogs are associated with fractional lifespan and working memory, and dogs with higher on/off leash gait speed are more active in the afternoon of weekdays. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 19, 2023

2023 journal article

Relationship between engagement with the impossible task, cognitive testing, and cognitive questionnaires in a population of aging dogs

FRONTIERS IN VETERINARY SCIENCE, 9.

By: M. Khan n, A. Mondino n, K. Russell n, B. Case n, G. Fefer n, H. Woods n, N. Olby n, M. Gruen n

author keywords: canine cognitive dysfunction syndrome; canine cognition; frustration; aging; dogs
TL;DR: The high correlation with several cognitive measures and the ease of administration of this test makes it a useful tool in evaluating canine cognitive dysfunction syndrome, however it is unclear if increased frustration or other cognitive processes are contributing to the observed changes. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: February 6, 2023

2023 journal article

Sleep and cognition in aging dogs. A polysomnographic study

FRONTIERS IN VETERINARY SCIENCE, 10.

By: A. Mondino n, M. Catanzariti*, D. Mateos*, M. Khan n, C. Ludwig n, A. Kis*, M. Gruen n, N. Olby n

author keywords: NREM sleep; REM sleep; canine cognitive dysfunction syndrome; quantitative EEG; power spectrum; coherence; complexity
TL;DR: Polysomnographic recordings in dogs can detect sleep-wakefulness cycle changes associated with dementia, and their potential clinical use to monitor the progression of canine cognitive dysfunction syndrome is evaluated. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: May 22, 2023

2023 journal article

Winning the race with aging: age-related changes in gait speed and its association with cognitive performance in dogs

FRONTIERS IN VETERINARY SCIENCE, 10.

By: A. Mondino n, M. Khan n, B. Case n, G. Fefer n, W. Panek n, M. Gruen n, N. Olby n

author keywords: canine cognitive dysfunction syndrome; canine gerontology; mobility; walking speed; memory; attention
TL;DR: Dogs' food-motivated gait speed off leash is correlated with fractional lifespan and cognitive performance in dogs, particularly in the domains of attention and working memory and proves to be a more effective indicator of age-related deterioration and cognitive decline than gaitspeed on leash. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: July 24, 2023

2022 article

Relationship between hearing, cognitive function, and quality of life in aging companion dogs

Fefer, G., Khan, M. Z., Panek, W. K., Case, B., Gruen, M. E., & Olby, N. J. (2022, August 6). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 8.

By: G. Fefer n, M. Khan n, W. Panek n, B. Case n, M. Gruen n & N. Olby n

author keywords: canine cognitive dysfunction syndrome; CCDS; cognitive testing; dementia; presbycusis
MeSH headings : Aging; Animals; Cognition; Dementia / epidemiology; Dog Diseases; Dogs; Hearing; Humans; Pets; Presbycusis / epidemiology; Presbycusis / veterinary; Prospective Studies; Quality of Life
TL;DR: Presbycusis negatively alters owner‐pet interactions and is associated with poor executive performance and owner‐assessed dementia severity, and in multivariate analysis, higher CADES score was associated with worse hearing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 22, 2022

2022 journal article

Use of Cognitive Testing, Questionnaires, and Plasma Biomarkers to Quantify Cognitive Impairment in an Aging Pet Dog Population

JOURNAL OF ALZHEIMERS DISEASE, 87(3), 1367–1378.

By: G. Fefer n, W. Panek n, M. Khan n, M. Singer n, H. Westermeyer n, F. Mowat n, D. Murdoch*, B. Case n, N. Olby n, M. Gruen n

author keywords: Blood biomarkers; canine cognitive dysfunction syndrome; CCDS; cognitive testing; dementia; neurofilament light chain; NfL
TL;DR: It is suggested that a multi-dimensional approach using a combination of questionnaires, specific cognitive tests, and pNfL concentration can be used to quantify cognitive decline in aging pet dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Sources: Web Of Science, ORCID
Added: June 20, 2022

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