Intensity of perioperative analgesia but not pre-treatment pain is predictive of survival in dogs undergoing amputation plus chemotherapy for extremity osteosarcoma
Nolan, M. W., Uzan, O. C., Green, N. A., Lana, S. E., & Lascelles, B. D. X. (2022, March 21). VETERINARY AND COMPARATIVE ONCOLOGY, Vol. 3.
author keywords: analgesia; cancer pain; cancer treatment pain; local anaesthesia; malignant osteolysis
MeSH headings : Amputation, Surgical / veterinary; Analgesia / veterinary; Animals; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Bone Neoplasms / drug therapy; Bone Neoplasms / surgery; Bone Neoplasms / veterinary; Dog Diseases / drug therapy; Dog Diseases / surgery; Dogs; Extremities / surgery; Osteosarcoma / drug therapy; Osteosarcoma / surgery; Osteosarcoma / veterinary; Pain / drug therapy; Pain / veterinary; Retrospective Studies; Treatment Outcome
TL;DR:
In dogs treated with limb amputation and adjunctive chemotherapy for osteosarcoma, oncologic outcomes are impacted by either baseline cancer pain severity, or the approaches used for perioperative pain management.
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