Works (3)
Updated: July 5th, 2023 15:40
2021 journal article
Single-minded 2 is required for left-right asymmetric stomach morphogenesis
DEVELOPMENT, 148(17).
author keywords: right asymmetry; Stomach; Morphogenesis; Pitx2; Sim2; Down syndrome; Frog
MeSH headings : Animals; Anura; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Body Patterning; Embryo, Nonmammalian; Endoderm / embryology; Endoderm / metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Morphogenesis; Stomach / embryology; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
It is demonstrated that sim2 functions downstream of LR patterning cues to regulate key cellular properties and behaviors in the left stomach epithelium that drive asymmetric curvature, and has implications for dose-dependent roles of laterality factors in non-laterality-related birth defects.
(via Semantic Scholar)
open access via doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 27, 2021
2017 journal article
Stomach curvature is generated by left-right asymmetric gut morphogenesis
DEVELOPMENT, 144(8), 1477–1483.
author keywords: Left-right; Asymmetry; Stomach; Gut; Morphogenesis; Pitx2; Xenopus; Mouse
MeSH headings : Animals; Body Patterning; Endoderm / embryology; Endoderm / metabolism; Epithelium / embryology; Epithelium / metabolism; Homeodomain Proteins / metabolism; Mice; Rotation; Signal Transduction; Stomach / anatomy & histology; Stomach / embryology; Transcription Factors / metabolism; Xenopus / embryology
TL;DR:
It is shown that the mechanisms that drive the curvature of the stomach are intrinsic to the gut tube itself, and this findings have implications for how LR patterning manifests distinct types of morphological asymmetries in different contexts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2015 journal article
Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology
DEVELOPMENTAL BIOLOGY, 405(2), 291–303.
author keywords: Lepidobatrachus; Xenopus; Amphibian; Embryo; Stages; Scaling
MeSH headings : Amphibians; Animals; Anura / embryology; Cell Lineage; Developmental Biology; Embryonic Development; Immunohistochemistry; Models, Animal; Morphogenesis; Organogenesis; Regeneration; Species Specificity; Xenopus laevis / physiology
TL;DR:
The Budgett's frog is described, an unusual species with eggs that are over twice the diameter of laboratory Xenopus, and embryos that can tolerate higher temperatures to develop into a tadpole four times more rapidly, which substantially accelerates the pace of experimentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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