Works (3)

Updated: July 5th, 2023 15:40

2021 journal article

Single-minded 2 is required for left-right asymmetric stomach morphogenesis


By: B. Wyatt n, N. Amin n, K. Bagley n, D. Wcisel n, M. Dush n, J. Yoder n, N. Nascone-Yoder n

author keywords: right asymmetry; Stomach; Morphogenesis; Pitx2; Sim2; Down syndrome; Frog
MeSH headings : Animals; Anura; Basic Helix-Loop-Helix Transcription Factors / genetics; Basic Helix-Loop-Helix Transcription Factors / metabolism; Body Patterning; Embryo, Nonmammalian; Endoderm / embryology; Endoderm / metabolism; Gene Expression Regulation, Developmental; Homeodomain Proteins / genetics; Homeodomain Proteins / metabolism; Morphogenesis; Stomach / embryology; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR: It is demonstrated that sim2 functions downstream of LR patterning cues to regulate key cellular properties and behaviors in the left stomach epithelium that drive asymmetric curvature, and has implications for dose-dependent roles of laterality factors in non-laterality-related birth defects. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 27, 2021

2017 journal article

Stomach curvature is generated by left-right asymmetric gut morphogenesis

DEVELOPMENT, 144(8), 1477–1483.

author keywords: Left-right; Asymmetry; Stomach; Gut; Morphogenesis; Pitx2; Xenopus; Mouse
MeSH headings : Animals; Body Patterning; Endoderm / embryology; Endoderm / metabolism; Epithelium / embryology; Epithelium / metabolism; Homeodomain Proteins / metabolism; Mice; Rotation; Signal Transduction; Stomach / anatomy & histology; Stomach / embryology; Transcription Factors / metabolism; Xenopus / embryology
TL;DR: It is shown that the mechanisms that drive the curvature of the stomach are intrinsic to the gut tube itself, and this findings have implications for how LR patterning manifests distinct types of morphological asymmetries in different contexts. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Budgett's frog (Lepidobatrachus laevis): A new amphibian embryo for developmental biology


By: N. Amin n, M. Womble n, C. Ledon-Rettig*, M. Hull n, A. Dickinson & N. Nascone-Yoder n

author keywords: Lepidobatrachus; Xenopus; Amphibian; Embryo; Stages; Scaling
MeSH headings : Amphibians; Animals; Anura / embryology; Cell Lineage; Developmental Biology; Embryonic Development; Immunohistochemistry; Models, Animal; Morphogenesis; Organogenesis; Regeneration; Species Specificity; Xenopus laevis / physiology
TL;DR: The Budgett's frog is described, an unusual species with eggs that are over twice the diameter of laboratory Xenopus, and embryos that can tolerate higher temperatures to develop into a tadpole four times more rapidly, which substantially accelerates the pace of experimentation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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