2020 journal article

Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota


By: R. Thanissery n, M. McLaren n, A. Rivera n, A. Reed n, N. Betrapally n, T. Burdette n, J. Winston n, M. Jacob n, B. Callahan n, C. Theriot n

author keywords: C. difficile; C. hiranonis; Microbiome; Ribotype; Antibiotic resistance; Animal; Canine; Equine; Feline
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Bacterial Typing Techniques; Cats; Chlorocebus aethiops; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Clostridium Infections / epidemiology; Clostridium Infections / microbiology; Clostridium Infections / veterinary; Coculture Techniques; Dogs; Feces / microbiology; Female; Gastrointestinal Microbiome; Horses; Hospitals, Animal; Host-Pathogen Interactions; Male; Microbial Interactions; Microbial Sensitivity Tests; North Carolina; Polymerase Chain Reaction; Prevalence; RNA, Ribosomal, 16S; Ribotyping; Risk Factors; Tertiary Healthcare; Vero Cells
TL;DR: Experimental results showed a clear antagonistic relationship between the two strains in vitro, suggesting that commensal Clostridia might play a role in colonization resistance against C. difficile in different hosts. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: January 11, 2021

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