Works (21)

2021 journal article

In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii

ACS SYNTHETIC BIOLOGY, 4.

Sources: ORCID, Web Of Science
Added: May 6, 2021

2021 article

What E. coli knows about your 1-year-old infant: Antibiotic use, lifestyle, birth mode, and siblings

Al'Abri, I. S., Durmusoglu, D., & Crook, N. (2021, June 9). CELL HOST & MICROBE, Vol. 6.

By: I. Al'Abri, D. Durmusoglu & N. Crook

Sources: Web Of Science, ORCID
Added: June 28, 2021

2020 article

Establishing Probiotic Saccharomyces boulardii as a Model Organism for Synthesis and Delivery of Biomolecules

Durmusoglu, D., Al’Abri, I., Collins, S. P., Beisel, C., & Crook, N. (2020, January 23). (Vol. 1). Vol. 1.

By: D. Durmusoglu, I. Al’Abri, S. Collins, C. Beisel & N. Crook

Source: ORCID
Added: May 6, 2021

2020 article

Inducible Directed Evolution of Complex Phenotypes in Bacteria

Al’Abri, I. S., Haller, D. J., & Crook, N. (2020, October 31). (Vol. 10). Vol. 10.

By: I. Al’Abri, D. Haller & N. Crook

Source: ORCID
Added: May 6, 2021

2020 journal article

Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut

ACS SYNTHETIC BIOLOGY, 9(5), 1010–1021.

By: N. Crook, A. Ferreiro, Z. Condiotte & G. Dantas

Sources: Web Of Science, ORCID
Added: June 8, 2020

2019 journal article

Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut

CELL HOST & MICROBE, 25(4), 499-+.

By: N. Crook, A. Ferreiro, A. Gasparrini, M. Pesesky, M. Gibson, B. Wang, X. Sun, Z. Condiotte ...

Sources: Web Of Science, ORCID
Added: April 29, 2019

2019 review

Barriers to genome editing with CRISPR in bacteria

[Review of ]. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 46(9-10), 1327–1341.

By: J. Vento, N. Crook & C. Beisel

Sources: Web Of Science, ORCID
Added: October 28, 2019

2018 article

Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut

Crook, N., Ferreiro, A., Gasparrini, A. J., Pesesky, M., Gibson, M. K., Wang, B., … Dantas, G. (2018, July 8). (Vol. 7). Vol. 7.

By: N. Crook, A. Ferreiro, A. Gasparrini, M. Pesesky, M. Gibson, B. Wang, X. Sun, Z. Condiotte ...

Source: ORCID
Added: May 6, 2021

2016 journal article

In vivo continuous evolution of genes and pathways in yeast

Nature Communications, 7(1).

By: N. Crook, J. Abatemarco, J. Sun, J. Wagner, A. Schmitz & H. Alper

Source: ORCID
Added: May 6, 2021

2014 journal article

Design of synthetic yeast promoters via tuning of nucleosome architecture

Nat Comms, 5.

By: K. Curran, N. Crook, A. Karim, A. Gupta, A. Wagman & H. Alper

Source: ORCID
Added: May 6, 2021

2014 journal article

Optimization of a Yeast RNA Interference System for Controlling Gene Expression and Enabling Rapid Metabolic Engineering

ACS Synth. Biol., 3(5), 307–313.

By: N. Crook, A. Schmitz & H. Alper

Source: ORCID
Added: May 6, 2021

2013 journal article

Model-based design of synthetic, biological systems

Chemical Engineering Science, 103, 2–11.

By: N. Crook & H. Alper

Source: ORCID
Added: May 6, 2021

2012 article

Classical Strain Improvement

Crook, N., & Alper, H. S. (2012, October). Engineering Complex Phenotypes in Industrial Strains, pp. 1–33.

By: N. Crook & H. Alper

Source: ORCID
Added: May 6, 2021

2012 journal article

Innovation at the intersection of synthetic and systems biology

Current Opinion in Biotechnology, 23(5), 712–717.

By: A. Lanza, N. Crook & H. Alper

Source: ORCID
Added: May 6, 2021

2012 journal article

Linking Yeast Gcn5p Catalytic Function and Gene Regulation Using a Quantitative, Graded Dominant Mutant Approach

PLoS ONE, 7(4), e36193.

By: A. Lanza, J. Blazeck, N. Crook & H. Alper

Ed(s): C. Chan

Source: ORCID
Added: May 6, 2021

2012 journal article

Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin

Journal of Molecular Biology, 422(2), 245–262.

By: E. Brustad, V. Lelyveld, C. Snow, N. Crook, S. Jung, F. Martinez, T. Scholl, A. Jasanoff, F. Arnold

Source: ORCID
Added: May 6, 2021

2011 journal article

Re-engineering multicloning sites for function and convenience

Nucleic Acids Research, 39(14), e92–e92.

By: N. Crook, E. Freeman & H. Alper

Source: ORCID
Added: May 6, 2021

2011 article

Using Flux Balance Analysis to Guide Microbial Metabolic Engineering

Curran, K. A., Crook, N. C., & Alper, H. S. (2011, November). Microbial Metabolic Engineering, pp. 197–216.

By: K. Curran, N. Crook & H. Alper

Source: ORCID
Added: May 6, 2021

2010 journal article

Improved product-per-glucose yields in P450-dependent propane biotransformations using engineered Escherichia coli

Biotechnol. Bioeng., 108(3), 500–510.

By: R. Fasan, N. Crook, M. Peters, P. Meinhold, T. Buelter, M. Landwehr, P. Cirino, F. Arnold

Source: ORCID
Added: May 6, 2021

2007 journal article

Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties

Angew. Chem., 119(44), 8566–8570.

By: R. Fasan, M. Chen, N. Crook & F. Arnold

Source: ORCID
Added: May 6, 2021

2007 journal article

Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties

Angew. Chem. Int. Ed., 46(44), 8414–8418.

By: R. Fasan, M. Chen, N. Crook & F. Arnold

Source: ORCID
Added: May 6, 2021

Employment

2014 - present

Washington University in Saint Louis Saint Louis, MO, US
Postdoctoral Research Associate Pathology

Education

2009 - 2014

University of Texas at Austin Austin, TX, US
Doctor of Philosophy Chemical Engineering

2005 - 2009

California Institute of Technology Pasadena, CA, US
Bachelor of Science Chemical Engineering