Nathan Crook

Li, Z., & Crook, N. C. (2024, February). Chips, guts, and gas: unraveling volatile microbial mysteries in real time! TRENDS IN BIOTECHNOLOGY, Vol. 42, pp. 144–146. https://doi.org/10.1016/j.tibtech.2023.12.009

Bang, R. S., Bergman, M., Li, T., Mukherjee, F., Alshehri, A. S., Abbott, N. L., … You, F. (2023, January 26). An integrated chemical engineering approach to understanding microplastics. AICHE JOURNAL, Vol. 1. https://doi.org/10.1002/aic.18020

Li, T., Menegatti, S., & Crook, N. (2023, September 14). Breakdown of polyethylene therepthalate microplastics under saltwater conditions using engineered Vibrio natriegens. AICHE JOURNAL, Vol. 9. https://doi.org/10.1002/aic.18228

Eroglu, A., Al'Abri, I. S., Kopec, R. E., Crook, N., & Bohn, T. (2023). [Review of Carotenoids and Their Health Benefits as Derived via Their Interactions with Gut Microbiota]. ADVANCES IN NUTRITION, 14(2), 238–255. https://doi.org/10.1016/j.advnut.2022.10.007

Bohn, T., Balbuena, E., Ulus, H., Iddir, M., Wang, G., Crook, N., & Eroglu, A. (2023). [Review of Carotenoids in Health as Studied by Omics-Related Endpoints]. ADVANCES IN NUTRITION, 14(6), 1538–1578. https://doi.org/10.1016/j.advnut.2023.09.002

Sohail, M., Pirzada, T., Guenther, R., Barbieri, E., Sit, T., Menegatti, S., … Khan, S. A. (2023). Cellulose Acetate-Stabilized Pickering Emulsions: Preparation, Rheology, and Incorporation of Agricultural Active Ingredients. ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 11(42), 15178–15191. https://doi.org/10.1021/acssuschemeng.3c02428

Sarma, S., Catella, C. M., Pedro, E. T. S., Xiao, X., Durmusoglu, D., Menegatti, S., … Hall, C. K. (2023, January 12). Design of 8-mer Peptides that BlockClostridioides difficileToxin A in Intestinal Cells. https://doi.org/10.1101/2023.01.10.523493

Sarma, S., Catella, C. M., San Pedro, E. T., Xiao, X., Durmusoglu, D., Menegatti, S., … Hall, C. K. (2023). Design of 8-mer peptides that block <i>Clostridioides difficile</i> toxin A in intestinal cells. COMMUNICATIONS BIOLOGY, 6(1). https://doi.org/10.1038/s42003-023-05242-x

Schaik, J., Li, Z., Cheadle, J., & Crook, N. (2023, September 15). Engineering the Maize Root Microbiome: A Rapid MoClo Toolkit and Identification of Potential Bacterial Chassis for Studying Plant-Microbe Interactions. ACS SYNTHETIC BIOLOGY, Vol. 9. https://doi.org/10.1021/acssynbio.3c00371

Schaik, J., Li, Z., Cheadle, J., & Crook, N. (2023, June 5). Engineering the Maize Root Microbiome: A Rapid MoClo Toolkit and Identification of Potential Bacterial Chassis for studying Plant-Microbe Interactions. https://doi.org/10.1101/2023.06.05.543168

Durmusoglu, D., Al'Abri, I., Li, Z., Islam Williams, T., Collins, L. B., Martinez, J. L., & Crook, N. (2023). Improving therapeutic protein secretion in the probiotic yeast Saccharomyces boulardii using a multifactorial engineering approach. MICROBIAL CELL FACTORIES, 22(1). https://doi.org/10.1186/s12934-023-02117-y

Durmusoglu, D., Haller, D. J., Al’Abri, I. S., Day, K., Sands, C., Clark, A., … Crook, N. C. (2023, November 17). Programming Probiotics: Diet-responsive gene expression and colonization control in engineeredS. boulardii. https://doi.org/10.1101/2023.11.17.567539

Al'Abri, I. S., Li, Z., Haller, D. J., & Crook, N. (2022). A Novel Method of Inducible Directed Evolution to Evolve Complex Phenotypes. BIO-PROTOCOL, 12(20). https://doi.org/10.21769/BioProtoc.4535

Heavey, M. K., Durmusoglu, D., Crook, N., & Anselmo, A. C. (2022). [Review of Discovery and delivery strategies for engineered live biotherapeutic products]. TRENDS IN BIOTECHNOLOGY, 40(3), 354–369. https://doi.org/10.1016/j.tibtech.2021.08.002

Jensen, E. D., Deichmann, M., Ma, X., Vilandt, R. U., Schiesaro, G., Rojek, M. B., … Jensen, M. K. (2022). Engineered cell differentiation and sexual reproduction in probiotic and mating yeasts. NATURE COMMUNICATIONS, 13(1). https://doi.org/10.1038/s41467-022-33961-y

Kwak, S., Crook, N., Yoneda, A., Ahn, N., Ning, J., Cheng, J., & Dantas, G. (2022). Functional mining of novel terpene synthases from metagenomes. BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 15(1). https://doi.org/10.1186/s13068-022-02189-9

Durmusoglu, D., Al’Abri, I., Williams, T. I., Collins, L. B., Martínez, J. L., & Crook, N. (2022, December 31). Improving Therapeutic Protein Secretion in the Probiotic YeastSaccharomyces boulardiiusing a Multifactorial Engineering Approach. BioRxiv. https://doi.org/10.1101/2022.12.30.522352

Al'Abri, I. S., Haller, D. J., Li, Z., & Crook, N. (2022, February 12). Inducible directed evolution of complex phenotypes in bacteria. NUCLEIC ACIDS RESEARCH, Vol. 2. https://doi.org/10.1093/nar/gkac094

Kwon, K. Y., Cheeseman, S., Frias‐De‐Diego, A., Hong, H., Yang, J., Jung, W., … Kim, T. (2021). A Liquid Metal Mediated Metallic Coating for Antimicrobial and Antiviral Fabrics. Advanced Materials, 33(45), 2104298. https://doi.org/10.1002/adma.202104298

Durmusoglu, D., Catella, C. M., Purnell, E. F., Menegatti, S., & Crook, N. C. (2021). Design and in situ biosynthesis of precision therapies against gastrointestinal pathogens. CURRENT OPINION IN PHYSIOLOGY, 23. https://doi.org/10.1016/j.cophys.2021.06.007

Xiao, X., Sarma, S., Menegatti, S., Crook, N., Magness, S. T., & Hall, C. K. (2021, December 29). In Silico Identification and Experimental Validation of Peptide-Based Inhibitors Targeting Clostridium difficile Toxin A. ACS CHEMICAL BIOLOGY, Vol. 17. https://doi.org/10.1021/acschembio.1c00743

Durmusoglu, D., Al'Abri, I. S., Collins, S. P., Cheng, J., Eroglu, A., Beisel, C. L., & Crook, N. (2021). In Situ Biomanufacturing of Small Molecules in the Mammalian Gut by Probiotic Saccharomyces boulardii. ACS SYNTHETIC BIOLOGY, 10(5), 1039–1052. https://doi.org/10.1021/acssynbio.0c00562

Al'Abri, I. S., Durmusoglu, D., & Crook, N. (2021, June 9). What E. coli knows about your 1-year-old infant: Antibiotic use, lifestyle, birth mode, and siblings. CELL HOST & MICROBE, Vol. 29, pp. 854–855. https://doi.org/10.1016/j.chom.2021.05.006

Durmusoglu, D., Al’Abri, I., Collins, S. P., Beisel, C., & Crook, N. (2020, January 23). Establishing Probiotic Saccharomyces boulardii as a Model Organism for Synthesis and Delivery of Biomolecules (Vol. 1). Vol. 1. https://doi.org/10.1101/2020.01.22.915389

Al’Abri, I. S., Haller, D. J., & Crook, N. (2020, October 31). Inducible Directed Evolution of Complex Phenotypes in Bacteria (Vol. 10). Vol. 10. https://doi.org/10.1101/2020.10.30.362871

Crook, N., Ferreiro, A., Condiotte, Z., & Dantas, G. (2020). Transcript Barcoding Illuminates the Expression Level of Synthetic Constructs in E. coli Nissle Residing in the Mammalian Gut. ACS SYNTHETIC BIOLOGY, 9(5), 1010–1021. https://doi.org/10.1021/acssynbio.0c00040

Crook, N., Ferreiro, A., Gasparrini, A. J., Pesesky, M. W., Gibson, M. K., Wang, B., … Dantas, G. (2019). Adaptive Strategies of the Candidate Probiotic E. coli Nissle in the Mammalian Gut. CELL HOST & MICROBE, 25(4), 499-+. https://doi.org/10.1016/j.chom.2019.02.005

Vento, J. M., Crook, N., & Beisel, C. L. (2019). [Review of Barriers to genome editing with CRISPR in bacteria]. JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY, 46(9-10), 1327–1341. https://doi.org/10.1007/s10295-019-02195-1

Crook, N., Ferreiro, A., Gasparrini, A. J., Pesesky, M., Gibson, M. K., Wang, B., … Dantas, G. (2018, July 8). Adaptive strategies of the candidate probiotic E. coli Nissle in the mammalian gut (Vol. 7). Vol. 7. https://doi.org/10.1101/364505

Crook, N., Abatemarco, J., Sun, J., Wagner, J. M., Schmitz, A., & Alper, H. S. (2016). In vivo continuous evolution of genes and pathways in yeast. Nature Communications. https://doi.org/10.1038/ncomms13051

Curran, K. A., Crook, N. C., Karim, A. S., Gupta, A., Wagman, A. M., & Alper, H. S. (2014). Design of synthetic yeast promoters via tuning of nucleosome architecture. Nat Comms, 5. https://doi.org/10.1038/ncomms5002

Crook, N. C., Schmitz, A. C., & Alper, H. S. (2014). Optimization of a Yeast RNA Interference System for Controlling Gene Expression and Enabling Rapid Metabolic Engineering. ACS Synth. Biol., 3(5), 307–313. https://doi.org/10.1021/sb4001432

Crook, N., & Alper, H. S. (2013). Model-based design of synthetic, biological systems. Chemical Engineering Science, 103, 2–11. https://doi.org/10.1016/j.ces.2012.12.022

Crook, N., & Alper, H. S. (2012, October). Classical Strain Improvement. Engineering Complex Phenotypes in Industrial Strains, pp. 1–33. https://doi.org/10.1002/9781118433034.ch1

Lanza, A. M., Crook, N. C., & Alper, H. S. (2012). Innovation at the intersection of synthetic and systems biology. Current Opinion in Biotechnology, 23(5), 712–717. https://doi.org/10.1016/j.copbio.2011.12.026

Lanza, A. M., Blazeck, J. J., Crook, N. C., & Alper, H. S. (2012). Linking Yeast Gcn5p Catalytic Function and Gene Regulation Using a Quantitative, Graded Dominant Mutant Approach. PLoS ONE, 7(4), e36193. https://doi.org/10.1371/journal.pone.0036193

Brustad, E. M., Lelyveld, V. S., Snow, C. D., Crook, N., Jung, S. T., Martinez, F. M., … Arnold, F. H. (2012). Structure-Guided Directed Evolution of Highly Selective P450-Based Magnetic Resonance Imaging Sensors for Dopamine and Serotonin. Journal of Molecular Biology, 422(2), 245–262. https://doi.org/10.1016/j.jmb.2012.05.029

Crook, N. C., Freeman, E. S., & Alper, H. S. (2011). Re-engineering multicloning sites for function and convenience. Nucleic Acids Research, 39(14), e92–e92. https://doi.org/10.1093/nar/gkr346

Curran, K. A., Crook, N. C., & Alper, H. S. (2011, November). Using Flux Balance Analysis to Guide Microbial Metabolic Engineering. Microbial Metabolic Engineering, pp. 197–216. https://doi.org/10.1007/978-1-61779-483-4_13

Fasan, R., Crook, N. C., Peters, M. W., Meinhold, P., Buelter, T., Landwehr, M., … Arnold, F. H. (2010). Improved product-per-glucose yields in P450-dependent propane biotransformations using engineered Escherichia coli. Biotechnol. Bioeng., 108(3), 500–510. https://doi.org/10.1002/bit.22984

Fasan, R., Chen, M. M., Crook, N. C., & Arnold, F. H. (2007). Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties. Angew. Chem., 119(44), 8566–8570. https://doi.org/10.1002/ange.200702616

Fasan, R., Chen, M. M., Crook, N. C., & Arnold, F. H. (2007). Engineered Alkane-Hydroxylating Cytochrome P450BM3 Exhibiting Nativelike Catalytic Properties. Angew. Chem. Int. Ed., 46(44), 8414–8418. https://doi.org/10.1002/anie.200702616