Works (2)

Updated: July 5th, 2023 15:36

2017 journal article

Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity

Biochemistry, 56(17), 2294–2303.

By: N. McCombs n, T. Moreno-Chicano*, L. Carey n, S. Franzen n, M. Hough* & R. Ghiladi n

Contributors: N. McCombs n, T. Moreno-Chicano*, L. Carey n, S. Franzen n, M. Hough* & R. Ghiladi n

MeSH headings : Amino Acid Motifs; Animals; Benzimidazoles / chemistry; Benzimidazoles / metabolism; Benzimidazoles / toxicity; Catalytic Domain; Computational Biology; Environmental Pollutants / chemistry; Environmental Pollutants / metabolism; Environmental Pollutants / toxicity; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / metabolism; Enzyme Inhibitors / toxicity; Fungicides, Industrial / chemistry; Fungicides, Industrial / metabolism; Fungicides, Industrial / toxicity; Hemoglobins / antagonists & inhibitors; Hemoglobins / chemistry; Hemoglobins / metabolism; Hydrogen Bonding; Hydrophobic and Hydrophilic Interactions; Imidazoles / chemistry; Imidazoles / metabolism; Imidazoles / toxicity; Indazoles / chemistry; Indazoles / metabolism; Indazoles / toxicity; Isoenzymes / antagonists & inhibitors; Isoenzymes / chemistry; Isoenzymes / metabolism; Kinetics; Ligands; Models, Molecular; Peroxidases / antagonists & inhibitors; Peroxidases / chemistry; Peroxidases / metabolism; Pesticides / chemistry; Pesticides / metabolism; Pesticides / toxicity; Polychaeta / enzymology; Recombinant Fusion Proteins / chemistry; Recombinant Fusion Proteins / metabolism; Recombinant Proteins / chemistry; Recombinant Proteins / metabolism; Triazoles / chemistry; Triazoles / metabolism; Triazoles / toxicity
TL;DR: The results demonstrate a new mechanism by which azole pollutants can potentially disrupt hemoglobin function, thereby improving the understanding of their impact on infaunal organisms in marine and aquatic environments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2017 journal article

Oxidation of pyrrole by dehaloperoxidase-hemoglobin: chemoenzymatic synthesis of pyrrolin-2-ones


By: N. McCombs n, T. Smirnova n & R. Ghiladi n

TL;DR: The results demonstrate the breadth of chemical reactivity afforded by dehaloperoxidase, and provide further evidence for establishing DHP as a multifunctional globin with practical applications as a biocatalyst. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.