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Works (7)
Updated: June 29th, 2024 05:02
2024 article
Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications
Sheridan, A., Nellenbach, K., Pandit, S., Byrnes, E., Hardy, G., Lutz, H., … Brown, A. C. (2024, June 5). ACS NANO, Vol. 6.
author keywords: nanogel; fibrin; thrombosis; hemorrhage; fibrinolytic; anticoagulant
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024
2024 journal article
Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma
SCIENCE TRANSLATIONAL MEDICINE, 16(742).
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 22, 2024
2023 journal article
Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass
Anesthesia & Analgesia, 137(3), 682–690.
TL;DR:
It is suggested that FC is effective in restoring structural fibrin clot properties after CPB, and further studies after the administration of FC in vivo are needed to validate this hypothesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 5, 2023
2022 journal article
COVID‐19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid
Journal of Thrombosis and Haemostasis, 20(12), 2909–2920.
author keywords: coagulopathy; COVID-19; fibrinogen; sialic acid; thrombosis
MeSH headings : Humans; Fibrinogen / metabolism; Fibrin / chemistry; N-Acetylneuraminic Acid; COVID-19; Polymerization; Neuraminidase; SARS-CoV-2; Fibrinolysis; Thrombosis / metabolism; Hemostatics
open access via www.ncbi.nlm.nih.gov (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: October 17, 2022
2021 article
Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates
Moiseiwitsch, N., Nellenbach, K. A., Guzzetta, N. A., Brown, A. C., & Downey, L. (2021, November 23). BLOOD, Vol. 138.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 6, 2022
2021 journal article
Fibrin‐specific <scp>poly(N‐isopropylacrylamide)</scp> nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo
Bioengineering & Translational Medicine, 7(2).
author keywords: disseminated intravascular coagulation; fibrin; nanogels; pNIPAM; targeted delivery; thrombosis; tissue plasminogen activator
TL;DR:
The therapeutic efficacy of targeted fibrin‐specific nanogel (FSN) design for targeted delivery of tPA to treat thrombotic complications is demonstrated and key translational parameters for tPA‐FSN therapeutics are evaluated, including optimal tPA •FSN dosage in a DIC rodent model and safety of intravenous tPA•FSN therapies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: December 20, 2021
2021 journal article
Neonatal coagulopathies: A review of established and emerging treatments
Experimental Biology and Medicine, 246(12), 1447–1457.
author keywords: Neonatal; coagulopathy; developmental hemostasis; transfusion
MeSH headings : Animals; Blood Coagulation Disorders / etiology; Blood Coagulation Disorders / therapy; Hemorrhage / etiology; Hemorrhage / therapy; Hemostasis / physiology; Humans; Infant, Newborn; Infant, Newborn, Diseases / etiology; Infant, Newborn, Diseases / therapy
TL;DR:
This mini-review examines the current understanding of neonatal hemostatic balance and treatment of Neonatal coagulopathies, with particular emphasis on emerging treatment methods and areas in need of further investigative efforts.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: July 12, 2021
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