Nina Alexandra Moiseiwitsch

Works (11)

Updated: October 29th, 2025 21:05

2025 journal article

Colloidal-Fibrillar Composite Gels Demonstrate Structural Reinforcement, Secondary Fibrillar Alignment, and Improved Vascular Healing Outcomes

Communications Engineering, 4, 67.

By: N. Moiseiwitsch n, S. Pandit n, N. Zwennes n, K. Nellenbach n, A. Sheridan n, J. LeGrand n, E. Chee n, S. Ozawa n  ...

topics (OpenAlex): Intracranial Aneurysms: Treatment and Complications; Connective tissue disorders research; Bone Tissue Engineering Materials
Sources: Web Of Science, NC State University Libraries, NC State University Libraries
Added: April 12, 2025

2025 article

Comparison of Intrarenal and Intravenous Injections of Sodium Pentobarbital for Euthanasia in New Zealand White Rabbits (Oryctolagus cuniculus)

LeGrand, J. L., Ozawa, S. M., Silverstein-Metzler, M. G., Estes, J. M., Moiseiwitsch, N. A., Stephens, J. Q., … Petritz, O. A. (2025, June 18). Journal of the American Association for Laboratory Animal Science, Vol. 64, pp. 770–777.

By: J. LeGrand n, S. Ozawa n , M. Silverstein-Metzler n, J. Estes n, N. Moiseiwitsch n, J. Stephens n, H. Atkins*, O. Petritz n 

topics (OpenAlex): Veterinary Pharmacology and Anesthesia; Anesthesia and Sedative Agents; Anesthesia and Pain Management
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Sources: Web Of Science, NC State University Libraries
Added: September 29, 2025

2024 article

Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications

Sheridan, A., Nellenbach, K., Pandit, S., Byrnes, E., Hardy, G., Lutz, H., … Brown, A. C. (2024, June 5). ACS Nano, Vol. 6.

By: A. Sheridan n, K. Nellenbach n, S. Pandit n, E. Byrnes n, G. Hardy n, H. Lutz  n, N. Moiseiwitsch n, G. Scull n ...

author keywords: nanogel; fibrin; thrombosis; hemorrhage; fibrinolytic; anticoagulant
MeSH headings : Animals; Humans; Male; Rats; Antithrombins / pharmacology; Antithrombins / chemistry; Antithrombins / administration & dosage; Blood Coagulation / drug effects; Disseminated Intravascular Coagulation / drug therapy; Drug Delivery Systems; Fibrin / metabolism; Fibrin / chemistry; Fibrinolytic Agents / pharmacology; Fibrinolytic Agents / chemistry; Fibrinolytic Agents / administration & dosage; Nanogels / chemistry; Thrombosis / drug therapy; Tissue Plasminogen Activator / pharmacology; Tissue Plasminogen Activator / administration & dosage; Tissue Plasminogen Activator / chemistry
topics (OpenAlex): Blood properties and coagulation; Blood Coagulation and Thrombosis Mechanisms; Trauma, Hemostasis, Coagulopathy, Resuscitation
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 article

Effect of In Vivo Administration of Fibrinogen Concentrate Versus Cryoprecipitate on Ex Vivo Clot Degradation in Neonates Undergoing Cardiac Surgery

Downey, L. A., Moiseiwitsch, N., Nellenbach, K., Xiang, Y., Brown, A. C., & Guzzetta, N. A. (2024, August 8). Anesthesia & Analgesia, Vol. 141, pp. 240–251.

By: L. Downey *, N. Moiseiwitsch n, K. Nellenbach n, Y. Xiang *, A. Brown n  & N. Guzzetta *

MeSH headings : Humans; Fibrinogen / administration & dosage; Fibrinogen / adverse effects; Infant, Newborn; Male; Female; Cardiac Surgical Procedures / adverse effects; Factor VIII / administration & dosage; Factor VIII / adverse effects; Blood Coagulation / drug effects; Treatment Outcome; Cardiopulmonary Bypass / adverse effects; Hemostatics / administration & dosage; Hemostatics / adverse effects; Blood Transfusion; Time Factors
topics (OpenAlex): Trauma, Hemostasis, Coagulopathy, Resuscitation; Blood transfusion and management; Cardiac and Coronary Surgery Techniques
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 28, 2025

2024 article

Point-of-Care Cardiac Troponin I Assay Evaluation in New Zealand White Rabbits (Oryctolagus cuniculus)

Ozawa, S. M., Pierce, K. V., Thomson, A., Moiseiwitsch, N. A., Stephens, J., LeGrand, J., … Mochizuki, H. (2024, September 5). Journal of the American Association for Laboratory Animal Science, Vol. 63, pp. 669–674.

By: S. Ozawa n , K. Pierce n , A. Thomson n, N. Moiseiwitsch n, J. Stephens n, J. LeGrand n, A. Brown n , H. Mochizuki n 

MeSH headings : Animals; Rabbits; Troponin I / blood; Troponin I / analysis; Reference Values; Point-of-Care Systems; Male; Muscle, Skeletal; Myocardium / metabolism; Female; Biomarkers / blood
topics (OpenAlex): Acute Myocardial Infarction Research; Cardiac Imaging and Diagnostics; Cardiac electrophysiology and arrhythmias
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 15, 2024

2024 journal article

Ultrasoft platelet-like particles stop bleeding in rodent and porcine models of trauma

Science Translational Medicine, 16(742).

By: K. Nellenbach n, E. Mihalko n, S. Nandi n, D. Koch n, J. Shetty *, L. Moretti *, J. Sollinger n, N. Moiseiwitsch n ...

MeSH headings : Animals; Mice; Swine; Rodentia / metabolism; Tissue Distribution; Blood Platelets / metabolism; Hemorrhage; Hemostatics; Fibrin / chemistry; Fibrin / metabolism
topics (OpenAlex): Trauma, Hemostasis, Coagulopathy, Resuscitation; Hemostasis and retained surgical items; Blood transfusion and management
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 22, 2024

2023 journal article

Influence of Fibrinogen Concentrate on Neonatal Clot Structure When Administered Ex Vivo After Cardiopulmonary Bypass

Anesthesia & Analgesia, 137(3), 682–690.

By: N. Moiseiwitsch n, K. Nellenbach n, L. Downey *, D. Boorman *, A. Brown n  & N. Guzzetta *

MeSH headings : Infant, Newborn; Humans; Fibrinogen / therapeutic use; Fibrinogen / metabolism; Cardiopulmonary Bypass / adverse effects; Hemostatics; Hemorrhage; Fibrin; Thrombosis
topics (OpenAlex): Cardiac and Coronary Surgery Techniques; Trauma, Hemostasis, Coagulopathy, Resuscitation; Hyperglycemia and glycemic control in critically ill and hospitalized patients
TL;DR: It is suggested that FC is effective in restoring structural fibrin clot properties after CPB, and further studies after the administration of FC in vivo are needed to validate this hypothesis. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 5, 2023

2022 journal article

COVID‐19 patient fibrinogen produces dense clots with altered polymerization kinetics, partially explained by increased sialic acid

Journal of Thrombosis and Haemostasis, 20(12), 2909–2920.

By: N. Moiseiwitsch n, N. Zwennes n, F. Szlam *, R. Sniecinski * & A. Brown n 

author keywords: coagulopathy; COVID-19; fibrinogen; sialic acid; thrombosis
MeSH headings : Humans; Fibrinogen / metabolism; Fibrin / chemistry; N-Acetylneuraminic Acid; COVID-19; Polymerization; Neuraminidase; SARS-CoV-2; Fibrinolysis; Thrombosis / metabolism; Hemostatics
topics (OpenAlex): Dermatological and COVID-19 studies; Blood properties and coagulation; COVID-19 Clinical Research Studies
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: October 17, 2022

2021 article

Ex Vivo and In Vivo Evaluation of Fibrinogen Concentrate to Mitigate Post-Surgical Bleeding in Neonates

Moiseiwitsch, N., Nellenbach, K. A., Guzzetta, N. A., Brown, A. C., & Downey, L. (2021, November 5). Blood, Vol. 138.

By: N. Moiseiwitsch n, K. Nellenbach n, N. Guzzetta *, A. Brown n  & L. Downey *

topics (OpenAlex): Trauma, Hemostasis, Coagulopathy, Resuscitation; Blood transfusion and management; Hyperglycemia and glycemic control in critically ill and hospitalized patients
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 6, 2022

2021 journal article

Fibrin‐specific poly(N‐isopropylacrylamide) nanogels for targeted delivery of tissue‐type plasminogen activator to treat thrombotic complications are well tolerated in vivo

Bioengineering & Translational Medicine, 7(2).

By: E. Mihalko n, K. Nellenbach n, M. Krishnakumar n, N. Moiseiwitsch n, J. Sollinger n, B. Cooley *, A. Brown n 

author keywords: disseminated intravascular coagulation; fibrin; nanogels; pNIPAM; targeted delivery; thrombosis; tissue plasminogen activator
topics (OpenAlex): Blood properties and coagulation; Blood Coagulation and Thrombosis Mechanisms; Protease and Inhibitor Mechanisms
TL;DR: The therapeutic efficacy of targeted fibrin‐specific nanogel (FSN) design for targeted delivery of tPA to treat thrombotic complications is demonstrated and key translational parameters for tPA‐FSN therapeutics are evaluated, including optimal tPA •FSN dosage in a DIC rodent model and safety of intravenous tPA•FSN therapies. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: December 20, 2021

2021 journal article

Neonatal coagulopathies: A review of established and emerging treatments

Experimental Biology and Medicine, 246(12), 1447–1457.

By: N. Moiseiwitsch n & A. Brown n 

author keywords: Neonatal; coagulopathy; developmental hemostasis; transfusion
MeSH headings : Animals; Blood Coagulation Disorders / etiology; Blood Coagulation Disorders / therapy; Hemorrhage / etiology; Hemorrhage / therapy; Hemostasis / physiology; Humans; Infant, Newborn; Infant, Newborn, Diseases / etiology; Infant, Newborn, Diseases / therapy
topics (OpenAlex): Blood Coagulation and Thrombosis Mechanisms; Trauma, Hemostasis, Coagulopathy, Resuscitation; Hemostasis and retained surgical items
TL;DR: This mini-review examines the current understanding of neonatal hemostatic balance and treatment of Neonatal coagulopathies, with particular emphasis on emerging treatment methods and areas in need of further investigative efforts. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: July 12, 2021

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