Nilesh Pandharinath Ingle

artificial intelligence, textiles, biomedical science

Works (33)

Updated: January 29th, 2026 14:20

2025 journal article

A review of the evolution and concepts of deep learning and AI in the textile industry

Textile Research Journal, 1.

By: N. Ingle n & W. Jasper n

author keywords: artificial intelligence; deep learning; machine learning; prediction modeling; textile automation
topics (OpenAlex): Industrial Vision Systems and Defect Detection; Textile materials and evaluations; Digital Transformation in Industry
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: January 16, 2025

2024 journal article

A review of deep learning and artificial intelligence in dyeing, printing and finishing

Textile Research Journal, 9.

By: N. Ingle n & W. Jasper n

author keywords: Automation; chemistry; dyeing; management of fabrication; printing; processing; production; systems; product and systems engineering
topics (OpenAlex): Dyeing and Modifying Textile Fibers; Textile materials and evaluations; Color Science and Applications
Sources: Crossref, NC State University Libraries, ORCID, Web Of Science
Added: September 22, 2024

2024 journal article

A review of deep learning within the framework of artificial intelligence for enhanced fiber and yarn quality

Textile Research Journal, 9.

By: N. Ingle n & W. Jasper n

author keywords: Automation; fabrication; fiber; yarn; fabric formation; processing; quality; spinning; systems; product and systems engineering
topics (OpenAlex): Textile materials and evaluations; Color Science and Applications; Industrial Vision Systems and Defect Detection
Sources: Crossref, NC State University Libraries, ORCID, Web Of Science
Added: September 22, 2024

2022 journal article

Artificial Intelligence in Agriculture: A perspective in 2022

International Journal of Extension Education, 18, 1–15.

By: N. Ingle

Source: NC State University Libraries
Added: February 4, 2025

2020 journal article

Polyplexes Are Endocytosed by and Trafficked within Filopodia

Biomacromolecules, 21(4), 1379–1392.

By: N. Ingle*, J. Hexum* & T. Reineke*

MeSH headings : Caveolae; Endocytosis; Genetic Therapy; HeLa Cells; Humans; Pseudopodia; Transfection
topics (OpenAlex): RNA Interference and Gene Delivery; Lipid Membrane Structure and Behavior; Force Microscopy Techniques and Applications
Sources: Crossref, NC State University Libraries
Added: January 25, 2025

2016 journal article

Fast, Efficient, and Gentle Transfection of Human Adherent Cells in Suspension

ACS Applied Materials & Interfaces, 8(14), 8870–8874.

MeSH headings : Cell Differentiation / genetics; Fibroblasts / cytology; Flow Cytometry; Gene Transfer Techniques; Genetic Therapy; Genetic Vectors; Humans; Induced Pluripotent Stem Cells / cytology; Transfection / methods
topics (OpenAlex): RNA Interference and Gene Delivery; CRISPR and Genetic Engineering; Microfluidic and Bio-sensing Technologies
Sources: Crossref, NC State University Libraries
Added: March 2, 2025

2015 journal article

Trehalose-Based Block Copolycations Promote Polyplex Stabilization for Lyophilization and in Vivo pDNA Delivery

ACS Biomaterials Science & Engineering, 2(1), 43–55.

By: Z. Tolstyka*, H. Phillips*, M. Cortez*, Y. Wu*, N. Ingle*, J. Bell*, P. Hackett*, T. Reineke*

topics (OpenAlex): RNA Interference and Gene Delivery; DNA and Nucleic Acid Chemistry; Neurogenetic and Muscular Disorders Research; Virus-based gene therapy research; Advanced biosensing and bioanalysis techniques
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2013 chapter book

Barbed suture technology

By: N. Ingle n, H. Cong n & M. King n

topics (OpenAlex): Surgical Sutures and Adhesives; Orthopedic Surgery and Rehabilitation; Facial Rejuvenation and Surgery Techniques
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2013 journal article

Highlighting the Role of Polymer Length, Carbohydrate Size, and Nucleic Acid Type in Potency of Glycopolycation Agents for pDNA and siRNA Delivery

Biomacromolecules, 14(11), 3903–3915.

By: L. Xue*, N. Ingle* & T. Reineke*

MeSH headings : Cell Line, Tumor; DNA / genetics; Gene Transfer Techniques; Humans; Molecular Conformation; Plasmids; Polyamines / chemical synthesis; Polyamines / chemistry; Polyelectrolytes; Polymerization; RNA, Small Interfering / genetics; Trehalose / chemistry; beta-Cyclodextrins / chemistry
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; Virus-based gene therapy research
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2013 journal article

Poly(trehalose): Sugar-Coated Nanocomplexes Promote Stabilization and Effective Polyplex-Mediated siRNA Delivery

Journal of the American Chemical Society, 135(41), 15417–15424.

By: A. Sizovs*, L. Xue*, Z. Tolstyka*, N. Ingle*, Y. Wu*, M. Cortez*, T. Reineke*

MeSH headings : Blood Proteins / chemistry; Carbohydrate Conformation; Cell Line, Tumor; Cell Survival; Glioblastoma / metabolism; Glioblastoma / pathology; Humans; Kinetics; Nanostructures / chemistry; Polymers / administration & dosage; Polymers / chemistry; Polymers / metabolism; RNA, Small Interfering / administration & dosage; RNA, Small Interfering / chemistry; RNA, Small Interfering / metabolism; Salts / chemistry; Trehalose / administration & dosage; Trehalose / analogs & derivatives; Trehalose / chemistry; Trehalose / metabolism
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced Polymer Synthesis and Characterization; Nanoparticle-Based Drug Delivery
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2013 journal article

Spatiotemporal Cellular Imaging of Polymer–pDNA Nanocomplexes Affords in Situ Morphology and Trafficking Trends

Molecular Pharmaceutics, 10(11), 4120–4135.

By: N. Ingle*, L. Xue* & T. Reineke*

MeSH headings : Colloids / chemistry; HeLa Cells; Humans; Nucleic Acids / chemistry; Plasmids / chemistry; Plasmids / metabolism; Polymers / chemistry
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; RNA Research and Splicing
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2012 conference paper

3D Imaging of intracellular nanoparticle polyplexes transporting nucleic acid in a cancer cell

IPrime Annual Meeting. Presented at the IPrime Annual Meeting, Minneapolis, MN.

By: N. Ingle, L. Xue & T. Reineke

Source: NC State University Libraries
Added: July 21, 2025

2012 journal article

MAG versus PEG: Incorporating a Poly(MAG) Layer to Promote Colloidal Stability of Nucleic Acid/“Click Cluster” Complexes

ACS Macro Letters, 1(5), 609–613.

By: D. Buckwalter*, A. Sizovs*, N. Ingle* & T. Reineke*

topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; DNA and Nucleic Acid Chemistry
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2012 journal article

Polymeric Nucleic Acid Vehicles Exploit Active Interorganelle Trafficking Mechanisms

ACS Nano, 7(1), 347–364.

By: K. Fichter*, N. Ingle*, P. McLendon* & T. Reineke*

MeSH headings : Animals; Cell Line; DNA / pharmacokinetics; Molecular Imaging / methods; Muscle Cells / cytology; Muscle Cells / metabolism; Nanocapsules / chemistry; Organelles / metabolism; Rats; Transfection / methods
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; RNA Research and Splicing
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2012 conference paper

Poster Presentation: Intracellular Trafficking Kinetics of Nucleic Acid Delivery Vehicles in Three Dimensions

American Society of Gene &Cell Therapy (ASGCT) 15th Annual Meeting. Presented at the American Society of Gene &Cell Therapy (ASGCT) 15th Annual Meeting, Philadelphia, PA.

By: N. Ingle, L. Xue & T. Reineke

Source: NC State University Libraries
Added: July 21, 2025

2012 conference paper

Spatio-temporal Analysis of Intracellular Trafficking of Polymeric Nucleic Acid Delivery Vehicles

American Chemical Society Spring Meeting. Presented at the American Chemical Society Spring Meeting, San Diego, CA.

By: N. Ingle, L. Xue & T. Reineke

Source: NC State University Libraries
Added: July 21, 2025

2011 conference paper

68. Methods To Observe Intracellular Trafficking of Non-Viral Delivery Vehicles in 3D

Molecular Therapy, 19, S27.

By: N. Ingle & T. Reineke

topics (OpenAlex): Recycling and Waste Management Techniques; Digital Economy and Work Transformation
Sources: Crossref, NC State University Libraries
Added: March 11, 2025

2011 journal article

Hybrid coaxial electrospun nanofibrous scaffolds with limited immunological response created for tissue engineering

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 99B(1), 180–190.

By: J. Gluck*, P. Rahgozar*, N. Ingle n, F. Rofail*, A. Petrosian*, M. Cline*, M. Jordan*, K. Roos* ...

Contributors: J. Gluck*, P. Rahgozar*, N. Ingle n, F. Rofail*, A. Petrosian*, M. Cline*, M. Jordan*, K. Roos* ...

author keywords: coaxial; electrospinning; polycaprolactone; polyurethane; gelatin; tissue engineering
MeSH headings : Animals; Biocompatible Materials / chemistry; Biocompatible Materials / metabolism; Electrochemical Techniques / methods; Foreign-Body Reaction / immunology; Gelatin / chemistry; Implants, Experimental; Materials Testing; Mice; NIH 3T3 Cells; Nanofibers / chemistry; Nanofibers / ultrastructure; Polyesters / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Polymers / metabolism; Polyurethanes / chemistry; Porosity; Stress, Mechanical; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds / chemistry
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Tissue Engineering and Regenerative Medicine; Bone Tissue Engineering Materials
TL;DR: The results show the advantages of combining both natural and synethic polymers to create a coaxial scaffold capable of withstanding dynamic culture conditions and encourage cellular migration to the interior of the scaffold for tissue-engineering applications. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: August 20, 2019

2011 journal article

Interaction of Poly(ethylenimine)–DNA Polyplexes with Mitochondria: Implications for a Mechanism of Cytotoxicity

Molecular Pharmaceutics, 8(5), 1709–1719.

By: G. Grandinetti*, N. Ingle* & T. Reineke*

MeSH headings : Apoptosis; Biological Transport / drug effects; Caspase 9 / metabolism; Cell Survival; Cell Tracking; DNA, Circular / chemistry; DNA, Circular / metabolism; Electron Transport Complex I / antagonists & inhibitors; Electron Transport Complex I / metabolism; Enzyme Activation; Enzyme Inhibitors / pharmacology; Fluorescent Dyes / chemistry; Gene Transfer Techniques / adverse effects; HeLa Cells; Humans; Kinetics; Materials Testing; Membrane Potential, Mitochondrial / drug effects; Mitochondria / chemistry; Mitochondria / metabolism; Mitochondria / ultrastructure; Mitochondrial Membrane Transport Proteins / antagonists & inhibitors; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Permeability Transition Pore; Mitochondrial Proton-Translocating ATPases / antagonists & inhibitors; Mitochondrial Proton-Translocating ATPases / metabolism; Permeability; Plasmids / chemistry; Plasmids / metabolism; Polyethyleneimine / adverse effects; Polyethyleneimine / chemistry; Polyethyleneimine / metabolism
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; DNA and Nucleic Acid Chemistry
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2011 conference paper

Knotless Barbed Sutures for Improved Tissue Fixation

Industrial Fabrics Association International (IFAI) Expo Asia Symposium. Presented at the Industrial Fabrics Association International (IFAI) Expo Asia Symposium, Singapore.

By: M. King & N. Ingle

Source: NC State University Libraries
Added: July 21, 2025

2011 journal article

Poly(glycoamidoamine)s: a broad class of carbohydrate-containing polycations for nucleic acid delivery

Trends in Biotechnology, 29(9), 443–453.

By: N. Ingle*, B. Malone* & T. Reineke*

MeSH headings : Animals; Carbohydrates / administration & dosage; Carbohydrates / chemistry; Cell Line; Humans; Nucleic Acids / administration & dosage; Nucleic Acids / chemistry; Pharmaceutical Vehicles / administration & dosage; Pharmaceutical Vehicles / chemistry; Polyamines / administration & dosage; Polyamines / chemistry; Polyelectrolytes; Transfection / methods
topics (OpenAlex): RNA Interference and Gene Delivery; Virus-based gene therapy research; Advanced biosensing and bioanalysis techniques
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2010 journal article

Finite element analysis of barbed sutures in skin and tendon tissues

Journal of Biomechanics, 43(5), 879–886.

By: N. Ingle n, M. King n & M. Zikry n

Contributors: N. Ingle n, M. King n & M. Zikry n

author keywords: Finite element analysis; Suture; Barbed; Tendon; Skin; Tissue
MeSH headings : Computer Simulation; Computer-Aided Design; Dermatologic Surgical Procedures; Equipment Design; Equipment Failure Analysis; Finite Element Analysis; Humans; Models, Biological; Skin Physiological Phenomena; Suture Techniques; Sutures; Tendons / physiology; Tendons / surgery
topics (OpenAlex): Surgical Sutures and Adhesives; Orthopedic Surgery and Rehabilitation; Botulinum Toxin and Related Neurological Disorders
TL;DR: This study is the first to establish a virtual prototyping and designing method for barbed sutures and provides the first report on how to develop a virtual bench top suture/tissue pullout testing environment. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Bioresorbable elastomeric vascular tissue engineering scaffolds via melt spinning and electrospinning

Acta Biomaterialia, 6(6), 1958–1967.

By: S. Chung n, N. Ingle n, G. Montero n, S. Kim* & M. King n

author keywords: Tissue engineering scaffolds; Elastomeric PLCL; Melt spinning; Electrospinning
MeSH headings : Absorbable Implants; Absorption; Animals; Biocompatible Materials / chemistry; Blood Vessels / cytology; Blood Vessels / growth & development; Cell Proliferation; Cell Survival / physiology; Elastomers / chemistry; Electrochemistry / methods; Hot Temperature; Materials Testing; Mice; NIH 3T3 Cells; Rotation; Tissue Engineering / instrumentation; Tissue Scaffolds
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Tissue Engineering and Regenerative Medicine; Bone Tissue Engineering Materials
TL;DR: The approach in this study has successfully demonstrated that these two techniques can be combined to produce double-layered tubular scaffolds containing both melt-spun macrofibers and electrospun submicron fibers. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2009 journal article

Optimizing the tissue anchoring performance of barbed sutures in skin and tendon tissues

Journal of Biomechanics, 43(2), 302–309.

By: N. Ingle n & M. King n

author keywords: Barbed suture; Polypropylene; Tendon; Skin; Suture/tissue pullout test
MeSH headings : Animals; Biomechanical Phenomena; Cattle; Dermatologic Surgical Procedures; In Vitro Techniques; Models, Animal; Polypropylenes; Sus scrofa; Suture Techniques; Sutures; Tendons / surgery; Tensile Strength
topics (OpenAlex): Surgical Sutures and Adhesives; Facial Rejuvenation and Surgery Techniques; Orthopedic Surgery and Rehabilitation
TL;DR: The experimental results revealed that since tendon tissue has a higher modulus than skin it needs a more rigid barb to penetrate and anchor the surrounding tissue, which will lead to the future development of a range of tissue-specific barbed sutures. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2009 journal article

The use of three-dimensional nanostructures to instruct cells to produce extracellular matrix for regenerative medicine strategies

Biomaterials, 30(27), 4665–4675.

By: K. Schenke-Layland*, F. Rofail*, S. Heydarkhan*, J. Gluck*, N. Ingle n, E. Angelis*, C. Choi*, W. MacLellan* ...

Contributors: K. Schenke-Layland*, F. Rofail*, S. Heydarkhan*, J. Gluck*, N. Ingle n, E. Angelis*, C. Choi*, W. MacLellan* ...

MeSH headings : Adipose Tissue / cytology; Biological Assay; Extracellular Matrix / drug effects; Extracellular Matrix / metabolism; Extracellular Matrix / ultrastructure; Extracellular Matrix Proteins / metabolism; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / metabolism; Fluorescence; Humans; Nanostructures / chemistry; Photons; Polyesters / pharmacology; Porosity / drug effects; Regenerative Medicine / methods; Stem Cells / cytology; Stem Cells / drug effects; Stem Cells / ultrastructure; Tissue Scaffolds
topics (OpenAlex): Electrospun Nanofibers in Biomedical Applications; Tissue Engineering and Regenerative Medicine; Graphene and Nanomaterials Applications
TL;DR: This study developed novel hybrid constructs composed of both strong biosynthetic materials and natural human ECM proteins that exhibited excellent biomechanical properties with fiber and pore sizes that allowed attachment and migration of adipose tissue-derived stem cells. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018

2008 conference paper

Construction of a manipulationaccessible virtual model of the human stomach

Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Annual Meeting. Presented at the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) Annual Meeting, Philadelphia, PA.

By: G. Kohn, N. Ingle, M. King & T. Farrell

Source: NC State University Libraries
Added: July 21, 2025

2007 journal article

Characterization of an Endovascular Prosthesis Using the 3Bs Rule (Biocompatibility, Biofunctionality and Biodurability): A Recommended Protocol to Investigate a Device Harvested at Necropsy

Journal of Long-Term Effects of Medical Implants, 17(3), 237–262.

By: Z. Xu*, Y. Fan*, R. Geelkerken*, X. Deng*, M. King n, A. Traore*, N. Ingle n, S. Turgeon* ...

MeSH headings : Aortic Aneurysm, Abdominal / pathology; Aortic Aneurysm, Abdominal / therapy; Blood Vessel Prosthesis Implantation; Equipment Design; Evaluation Studies as Topic; Fatal Outcome; Humans; Male; Materials Testing; Middle Aged; Stents
topics (OpenAlex): Cardiac Valve Diseases and Treatments; Aortic Disease and Treatment Approaches; Orthopaedic implants and arthroplasty
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 26, 2025

2007 conference paper

Effect of Sterilization on Dynamic Mechanical Properties of Electrospun Tissue Engineering Scaffold

Society for Biomaterials Conference. Presented at the Society for Biomaterials Conference, Chicago, IL.

By: J. Gluck, N. Ingle & M. King

Source: NC State University Libraries
Added: July 21, 2025

2007 journal article

Tissue holding performance of barbed surgical sutures

Journal of Donghua University, 24(2), 61–66.

By: N. Ingle & M. King

Source: NC State University Libraries
Added: July 21, 2025

2005 journal article

Analysis of Sunnhemp fibers processed using jute spinning system

Industrial Crops and Products, 23(3), 235–243.

By: N. Ingle* & S. Doke

author keywords: Sunnhemp; carding; drawing; distribution; fiber; entity; bast
topics (OpenAlex): Textile materials and evaluations; Natural Fiber Reinforced Composites
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2005 journal article

Optimisation of spinning parameters for processing of 100% sunnhemp fibers

Industrial Crops and Products, 23(3), 225–234.

By: N. Ingle* & S. Doke*

author keywords: sunnhemp; carding; drawing; count strength product (CSP); tensile; energy at break; twist
topics (OpenAlex): Textile materials and evaluations
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2005 conference paper

Testing the tissue holding capacity of barbed sutures

Fiber Society Conference. Presented at the Fiber Society Conference, New Jersey, NJ.

By: N. Ingle & M. King

Source: NC State University Libraries
Added: July 21, 2025

2004 conference paper

Barbed suture anchoring strength: Applicability to dissimilar polymeric materials

7th World Biomaterials Congress. Presented at the 7th World Biomaterials Congress, Sydney, Australia.

By: N. Ingle, M. King, J. Leung & S. Batchelor

Source: NC State University Libraries
Added: July 21, 2025

Employment

Updated: January 23rd, 2025 05:53

2024 - present

North Carolina State University Raleigh, US
Adjunct Assistant Professor Textile Engineering, Chemistry and Science

2012 - present

University of Minnesota Minneapolis, MN, US
Research Associate Chemistry

Education

Updated: March 31st, 2014 10:59

2003 - 2009

North Carolina State University, Raleigh and University of North Carolina, Chapel Hill Raleigh, NC, US
Ph.D. Dual Major: (1) Biomedical Engineering, (2) Fiber & Polymer Science

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