@article{shymanska_pierce_2017, title={Stereoselective Synthesis of Quaternary Pyrrolidine-2,3-diones and beta-Amino Acids}, volume={19}, ISSN={["1523-7052"]}, url={https://doi.org/10.1021/acs.orglett.7b01185}, DOI={10.1021/acs.orglett.7b01185}, abstractNote={A facile, diastereoselective synthesis of highly substituted pyrrolidine-2,3-diones is reported, along with the one-step conversion of these heterocycles to novel β-amino acids and further functionalized derivatives. This method involves an unusually mild, one-pot, three-component cyclization/allylation followed by a Claisen rearrangement to provide unusual pyrrolidinone products that are densely functionalized and contain an all-carbon quaternary stereocenter. The reported reaction sequence is operationally simple, exquisitely diastereoselective, and provides gram-scale access to valuable heterocyclic scaffolds and β-amino acids not readily accessible via existing approaches.}, number={11}, journal={ORGANIC LETTERS}, publisher={American Chemical Society (ACS)}, author={Shymanska, Nataliia V. and Pierce, Joshua G.}, year={2017}, month={Jun}, pages={2961–2964} }
 @article{shymanska_an_guevara-zuluaga_pierce_2015, title={Rapid synthesis and antimicrobial activity of novel 4-oxazolidinone heterocycles}, volume={25}, ISSN={["1464-3405"]}, DOI={10.1016/j.bmcl.2015.06.003}, abstractNote={The synoxazolidinone family of marine natural products bear an unusual 4-oxazolidinone heterocyclic core and promising antimicrobial activity against several strains of pathogenic bacteria. As part of our research program directed at the synthesis and chemical biology of this family of natural products we have developed a one-step method for the generation of variously substituted 4-oxazolidinone scaffolds from readily available materials. These studies revealed the importance of an electron deficient aromatic ring for antimicrobial activity and serve as the basis for future SAR studies around the 4-oxazolidinone core.}, number={21}, journal={BIOORGANIC & MEDICINAL CHEMISTRY LETTERS}, author={Shymanska, Nataliia V. and An, Il Hwan and Guevara-Zuluaga, Sebastian and Pierce, Joshua G.}, year={2015}, month={Nov}, pages={4887–4889} }
 @article{shymanska_an_pierce_2014, title={A Rapid Synthesis of 4-Oxazolidinones: Total Synthesis of Synoxazolidinones A and B**}, volume={53}, ISSN={["1521-3773"]}, DOI={10.1002/anie.201402310}, abstractNote={AbstractA five‐step total synthesis of the marine natural product synoxazolidinone A was achieved through a diastereoselective imine acylation/cyclization cascade. Synoxazolidinone B and a series of analogues were also prepared to explore the potential of these 4‐oxazolidinone natural products as antimicrobial agents. These studies confirmed the importance of the chlorine substituent for antimicrobial activity and revealed simplified dichloro derivatives that are equally potent against several bacterial strains.}, number={21}, journal={ANGEWANDTE CHEMIE-INTERNATIONAL EDITION}, author={Shymanska, Nataliia V. and An, Il Hwan and Pierce, Joshua G.}, year={2014}, month={May}, pages={5401–5404} }