@article{zidan_medland_olby_2020, title={Long-term postoperative pain evaluation in dogs with thoracolumbar intervertebral disk herniation after hemilaminectomy}, volume={34}, ISSN={["1939-1676"]}, url={https://doi.org/10.1111/jvim.15800}, DOI={10.1111/jvim.15800}, abstractNote={Abstract}, number={4}, journal={JOURNAL OF VETERINARY INTERNAL MEDICINE}, author={Zidan, Natalia and Medland, Julia and Olby, Natasha}, year={2020}, month={Jul}, pages={1547–1555} } @article{guevar_zidan_durand_olby_2020, title={Minimally invasive spine surgery in dogs: Evaluation of the safety and feasibility of a thoracolumbar approach to the spinal cord}, volume={49}, ISSN={0161-3499 1532-950X}, url={http://dx.doi.org/10.1111/vsu.13385}, DOI={10.1111/vsu.13385}, abstractNote={Abstract}, journal={Veterinary Surgery}, publisher={Wiley}, author={Guevar, Julien and Zidan, Natalia and Durand, Alexane and Olby, Natasha J.}, year={2020}, month={Jan}, pages={O76–O85} } @article{zidan_sims_fenn_williams_griffith_early_mariani_munana_guevar_olby_et al._2018, title={A randomized, blinded, prospective clinical trial of postoperative rehabilitation in dogs after surgical decompression of acute thoracolumbar intervertebral disc herniation}, volume={32}, ISSN={0891-6640}, url={http://dx.doi.org/10.1111/jvim.15086}, DOI={10.1111/jvim.15086}, abstractNote={BackgroundExperimental evidence shows benefit of rehabilitation after spinal cord injury (SCI) but there are limited objective data on the effect of rehabilitation on recovery of dogs after surgery for acute thoracolumbar intervertebral disc herniations (TL‐IVDH).}, number={3}, journal={Journal of Veterinary Internal Medicine}, publisher={Wiley}, author={Zidan, Natalia and Sims, Cory and Fenn, Joe and Williams, Kim and Griffith, Emily and Early, Peter J. and Mariani, Chris L. and Munana, Karen and Guevar, Julien and Olby, Natasha J. and et al.}, year={2018}, month={Apr}, pages={1133–1144} } @article{moore_zidan_spitzbarth_nout-lomas_granger_da costa_levine_jeffery_stein_tipold_et al._2018, title={Development of an International Canine Spinal Cord Injury observational registry: a collaborative data-sharing network to optimize translational studies of SCI}, volume={56}, ISSN={1362-4393 1476-5624}, url={http://dx.doi.org/10.1038/s41393-018-0145-4}, DOI={10.1038/s41393-018-0145-4}, abstractNote={Prospective cross-sectional cohort study.The canine spontaneous model of spinal cord injury (SCI) is as an important pre-clinical platform as it recapitulates key facets of human injury in a naturally occurring context. The establishment of an observational canine SCI registry constitutes a key step in performing epidemiologic studies and assessing the impact of therapeutic strategies to enhance translational research. Further, accumulating information on dogs with SCI may contribute to current "big data" approaches to enhance understanding of the disease using heterogeneous multi-institutional, multi-species datasets from both pre-clinical and human studies.Multiple veterinary academic institutions across the United States and Europe.Common data elements recommended for experimental and human SCI studies were reviewed and adapted for use in a web-based registry, to which all dogs presenting to member veterinary tertiary care facilities were prospectively entered over ~1 year.Analysis of data accumulated during the first year of the registry suggests that 16% of dogs with SCI present with severe, sensorimotor-complete injury and that 15% of cases are seen by a tertiary care facility within 8 h of injury. Similar to the human SCI population, 34% were either overweight or obese.Severity of injury and timing of presentation suggests that neuroprotective studies using the canine clinical model could be conducted efficiently using a multi-institutional approach. Additionally, pet dogs with SCI experience similar comorbidities to people with SCI, in particular obesity, and could serve as an important model to evaluate the effects of this condition.}, number={7}, journal={Spinal Cord}, publisher={Springer Science and Business Media LLC}, author={Moore, Sarah A. and Zidan, Natalia and Spitzbarth, Ingo and Nout-Lomas, Yvette S. and Granger, Nicolas and da Costa, Ronaldo C. and Levine, Jonathan M. and Jeffery, Nick D. and Stein, Veronika M. and Tipold, Andrea and et al.}, year={2018}, month={May}, pages={656–665} } @article{zidan_fenn_griffith_early_mariani_muñana_guevar_olby_2018, title={The Effect of Electromagnetic Fields on Post-Operative Pain and Locomotor Recovery in Dogs with Acute, Severe Thoracolumbar Intervertebral Disc Extrusion: A Randomized Placebo-Controlled, Prospective Clinical Trial}, volume={35}, ISSN={0897-7151 1557-9042}, url={http://dx.doi.org/10.1089/neu.2017.5485}, DOI={10.1089/neu.2017.5485}, abstractNote={Spinal cord injury (SCI) attributed to acute intervertebral disc extrusions (IVDEs) is common in dogs and is treated by surgical decompression. Dogs with sensorimotor complete injuries have an incomplete recovery. Pulsed electromagnetic fields (PEMFs) reduce post-operative pain through anti-inflammatory effects and there is growing evidence for neuroprotective effects. This randomized, controlled clinical trial evaluated the effect of PEMF on post-operative pain and neurological recovery in dogs with surgically treated sensorimotor complete SCI attributed to acute IVDE. Sixteen dogs with surgically treated complete thoracolumbar SCI were randomized to receive PEMF (15 min every 2 h for 2 weeks then twice-daily for 4 weeks) or placebo starting immediately after diagnosis. The primary outcome was gait score at 2 weeks. Secondary measures of gait, pain perception, and proprioceptive function were evaluated at 2 and 6 weeks. Plasma glial fibrillary acidic protein (GFAP) concentration was measured as an SCI biomarker. Post-operative pain was quantified by measuring mechanical sensory thresholds (MSTs) at control and surgical sites. There was no significant difference in demographics or GFAP concentration between the two groups at trial entry. There was no difference in primary outcome or in secondary measures of gait, but proprioceptive placing was significantly better at 6 weeks and GFAP concentrations were significantly lower at 2 weeks in the PEMF group. MSTs were significantly higher in the PEMF-treated group. We conclude that PEMF reduced incision-associated pain in dogs post-surgery for IVDE and may reduce extent of SCI and enhance proprioceptive placing. Larger clinical trials are warranted.}, number={15}, journal={Journal of Neurotrauma}, publisher={Mary Ann Liebert Inc}, author={Zidan, Natalia and Fenn, Joe and Griffith, Emily and Early, Peter J. and Mariani, Chris L. and Muñana, Karen R. and Guevar, Julien and Olby, Natasha J.}, year={2018}, month={Aug}, pages={1726–1736} }