Cadmium disrupts signaling of the hypoxia-inducible (HIF) and transforming growth factor (TGF-beta) pathways in placental JEG-3 trophoblast cells via reactive oxygen species
TOXICOLOGY AND APPLIED PHARMACOLOGY, 342, 108–115.
United States of America 🇺🇸
author keywords: Reactive oxygen species; Hypoxia; Placentation; Growth factor; Gene expression; Cadmium
MeSH headings :
Cadmium / toxicity; Cell Line, Tumor; Dose-Response Relationship, Drug; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit / antagonists & inhibitors; Hypoxia-Inducible Factor 1, alpha Subunit / metabolism; Placenta / cytology; Placenta / drug effects; Placenta / metabolism; Pregnancy; Reactive Oxygen Species / metabolism; Signal Transduction / drug effects; Signal Transduction / physiology; Transforming Growth Factor beta / antagonists & inhibitors; Transforming Growth Factor beta / metabolism; Trophoblasts / drug effects; Trophoblasts / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018