Orlando Arguello-Miranda

Also known as: Alejandrolvido (GitHub)


Cell Biology; Machine Learning; Spectral microscopy

Orlando Argüello-Miranda grew up in Costa Rica. After receiving a B.Sc. from the National University, he moved to Germany to pursue a PhD in cell biology at the Max Planck Institute for Cell Biology and Genetics in Dresden. He completed his doctoral dissertation working at the Max Planck Institute for Biochemistry in Munich. His thesis described the regulatory protein network that controls major transitions during specialized forms of cell division, such as meiosis. Heavily trained as a biochemist, Orlando is now focused on using spectral imaging and machine learning to obtain mechanistic molecular insight from fluorescently labelled cellular quiescence processes. He is supported by a K99 Pathway to Independence Award (NIGMS) from the National Institutes of Health. When not in the lab, Orlando likes to spend time traveling around with his wife and daughter and writing science fiction.

Works (11)

Updated: April 18th, 2023 09:04

2022 article

Cdc14 plans autophagy for meiotic cell divisions

Feng, W., Arguello-Miranda, O., Qian, S., & Wang, F. (2022, May 28). AUTOPHAGY, Vol. 18.

By: W. Feng*, O. Arguello-Miranda, S. Qian* & F. Wang*

author keywords: Atg1; Atg13; autophagy; Cdc14; meiosis; phosphatase; sporulation
Sources: Web Of Science, ORCID
Added: June 6, 2022

2022 journal article

Cdc14 spatiotemporally dephosphorylates Atg13 to activate autophagy during meiotic divisions


By: W. Feng*, O. Arguello-Miranda, S. Qian* & F. Wang*

Sources: ORCID, Web Of Science
Added: July 11, 2022

2022 journal article

Cell cycle-independent integration of stress signals by Xbp1 promotes Non-G1/G0 quiescence entry


By: O. Arguello-Miranda, A. Marchand*, T. Kennedy*, M. Russo* & J. Noh*

Sources: ORCID, Web Of Science
Added: November 8, 2021

2022 journal article

Live-cell fluorescence spectral imaging as a data science challenge

Biophysical Reviews.

By: J. Acuña-Rodriguez*, J. Mena-Vega* & O. Argüello-Miranda

Source: ORCID
Added: July 11, 2022

2020 journal article

Functional interrelationships between carbohydrate and lipid storage, and mitochondrial activity during sporulation in Saccharomyces cerevisiae


author keywords: cyclin 3; glycogen; lipid droplet; meiosis; trehalose; yeast
Source: ORCID
Added: July 11, 2022

2019 journal article

Meiosis research in orphan and non-orphan tropical crops

Frontiers in Plant Science, 10, 1–7.

By: P. Bolaños-Villegas* & O. Argüello-Miranda

author keywords: meiosis; plant breeding; genetic diversity; tropical agriculture; food security; climate change
Source: ORCID
Added: July 11, 2022

2018 journal article

Integration of Multiple Metabolic Signals Determines Cell Fate Prior to Commitment

Molecular Cell, 71(5), 733–744.e11.

By: O. Argüello-Miranda, Y. Liu*, N. Wood*, P. Kositangool* & A. Doncic*

Source: ORCID
Added: July 11, 2022

2017 journal article

Casein Kinase 1 Coordinates Cohesin Cleavage, Gametogenesis, and Exit from M Phase in Meiosis II

Developmental Cell, 40(1), 37–52.

By: O. Argüello-Miranda, I. Zagoriy*, V. Mengoli*, J. Rojas*, K. Jonak*, T. Oz*, P. Graf*, W. Zachariae*

Source: ORCID
Added: July 11, 2022

2017 journal article

Towards a Unified Understanding of Lithium Action in Basic Biology and its Significance for Applied Biology

Journal of Membrane Biology, 250(6), 587–604.

By: E. Jakobsson*, O. Argüello-Miranda, S. Chiu*, Z. Fazal*, J. Kruczek*, S. Nunez-Corrales*, S. Pandit*, L. Pritchet*

author keywords: Ion channels and transporters; Magnesium-dependent enzymes; Physical properties of biological membranes
Source: ORCID
Added: July 11, 2022

2012 journal article

Meiotic prophase requires proteolysis of m phase regulators mediated by the meiosis-specific APC/CAma1

Cell, 151(3), 603–618.

By: E. Okaz*, O. Argüello-Miranda, A. Bogdanova*, P. Vinod*, J. Lipp*, Z. Markova*, I. Zagoriy*, B. Novak*, W. Zachariae*

Source: ORCID
Added: July 11, 2022

2008 journal article

Interchromatidal central ridge and transversal symmetry in early metaphasic human chromosome one

Journal of Molecular Recognition, 21(3), 184–189.

By: O. Argüello-Miranda & G. Sáenz-Arce*

Source: ORCID
Added: July 11, 2022


Updated: March 15th, 2023 14:48

2022 - present

North Carolina State University Raleigh, North Carolina, US
Assistant Professor Plant and Microbial Biology

2016 - 2021

University of Texas Southwestern Medical Center TX, TX, US
Postdoctoral Researcher Cell Biology/Bioinformatics


Updated: February 26th, 2020 10:58

2012 - 2015

Max-Planck-Institut für Biochemie Martinsried, Bayern, DE
PHD Chromosome Biology

Funding History

Funding history based on the linked ORCID record. Updated: January 1st, 2021 22:55

grant March 1, 2020 - February 28, 2022
Systems biology of quiescence entry
National Institute of General Medical Sciences