Prema Arasu
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Works (11)
Updated: April 4th, 2024 00:35
2007 journal article
A novel gene from Brugia sp that encodes a cytotoxic fatty acid binding protein allergen recognized by canine monoclonal IgE and serum IgE from infected dogs
JOURNAL OF PARASITOLOGY, 93(6), 1378–1387.
MeSH headings : Allergens / chemistry; Allergens / genetics; Allergens / immunology; Amino Acid Sequence; Animals; Antibodies, Helminth / immunology; Antibodies, Monoclonal / immunology; Antigens, Helminth / chemistry; Antigens, Helminth / genetics; Antigens, Helminth / immunology; B-Lymphocytes / immunology; Base Sequence; Blotting, Western; Brugia / genetics; Brugia / immunology; Brugia pahangi / genetics; Brugia pahangi / immunology; Disease Models, Animal; Dogs; Epitopes / immunology; Fatty Acid-Binding Proteins / chemistry; Fatty Acid-Binding Proteins / genetics; Fatty Acid-Binding Proteins / immunology; Female; Filariasis / immunology; Filariasis / parasitology; Gerbillinae; Glutathione Transferase / genetics; Glutathione Transferase / immunology; Immunoglobulin E / blood; Immunoglobulin E / immunology; Male; Molecular Sequence Data; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology; Sequence Homology
TL;DR:
This 35-kDa protein seems to be highly conserved in different stages and species of filarids, and it represents a previously unknown allergen that is possibly involved in the pathogenesis of filarial disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Impact of population structure on genetic diversity of a potential vaccine target in the canine hookworm (Ancylostoma caninum)
JOURNAL OF PARASITOLOGY, 93(4), 796–805.
MeSH headings : Ancylostoma / genetics; Ancylostoma / growth & development; Ancylostoma / immunology; Ancylostomiasis / parasitology; Ancylostomiasis / veterinary; Animals; DNA, Helminth / chemistry; Dog Diseases / parasitology; Dogs; Electron Transport Complex IV / genetics; Electron Transport Complex IV / immunology; Female; Genetic Variation; Haplotypes; Helminth Proteins / genetics; Helminth Proteins / immunology; Male; Maryland; North Carolina; Population Dynamics; Queensland; Vaccines / genetics; Vaccines / immunology
TL;DR:
Test whether positive selection, population structure, or both affect genetic variation at the candidate vaccine target Ancylostoma secreted protein 1 (asp-1), using the statistical population analysis tools found in the SNAP Workbench.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2005 journal article
Cloning and characterisation of genes encoding two transforming growth factor-beta-like ligands from the hookworm, Ancylostoma caninum
INTERNATIONAL JOURNAL FOR PARASITOLOGY, 35(14), 1477–1487.
author keywords: Ancylostoma caninum; TGF-beta; dbl-1; daf-7; development
MeSH headings : Amino Acid Sequence; Ancylostoma / genetics; Animals; Base Sequence; Caenorhabditis elegans Proteins / genetics; Cloning, Molecular; Fluorescent Antibody Technique; Gene Expression Regulation, Developmental; Larva; Molecular Sequence Data; Receptors, Transforming Growth Factor beta / analysis; Receptors, Transforming Growth Factor beta / genetics; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology
TL;DR:
Immunofluorescent studies showed that Ac-daf-7 is expressed in the anterior region of the iL3 similar to Ce-dft-7, which is localised to the ASI chemosensory neurons, which may be unique to parasitic nematodes that have an obligate requirement to undergo developmental arrest.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Evaluation of endogenous reference genes for real-time PCR quantification of gene expression in Ancylostoma caninum
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 143(2), 241–244.
author keywords: Ancylostoma hookworms; real-time PCR; validation; reference gene
MeSH headings : Ancylostoma / genetics; Animals; Gene Expression; Gene Expression Profiling / methods; Genes, Helminth; Quality Control; Reference Standards; Reverse Transcriptase Polymerase Chain Reaction / standards
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2005 journal article
Gene expression profiles associated with the transition to parasitism in Ancylostoma caninum larvae
Molecular and Biochemical Parasitology, 143(1), 39–48.
Source: NC State University Libraries
Added: August 6, 2018
2005 journal article
Investigating hookworm genomes by comparative analysis of two Ancylostoma species
BMC Genomics, 6.
Source: NC State University Libraries
Added: August 6, 2018
2001 journal article
In vitro reactivation of Ancylostoma caninum tissue-arrested third-stage larvae by transforming growth factor-beta
JOURNAL OF PARASITOLOGY, 87(4), 733–738.
TL;DR:
The hypothesis that during pregnancy, host-derived TGF-β can signal a parasite-encoded receptor to trigger the reactivation of tissue-arrested larvae is supported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Antibody responses in pregnancy-induced transmammary transmission of Ancylostoma caninum hookworm larvae
VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 70(3-4), 289–298.
author keywords: Ancylostoma caninum; mouse; antibody; immunosuppression; transmammary transfer
MeSH headings : Ancylostoma; Ancylostomiasis / transmission; Animals; Antibodies, Helminth / biosynthesis; Dogs; Feces / parasitology; Female; Infectious Disease Transmission, Vertical; Lactation; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Pregnancy; Pregnancy Complications, Parasitic / immunology
TL;DR:
To determine if the suppression of parasite-specific antibody responses during pregnancy facilitates the reactivation and transmammary transfer of hookworm larvae, a murine model of A. caninum infection was used and it was confirmed that larval transfer to the mouse pups only occurred during the post-partum lactational period.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Control of gastrointestinal parasite larvae of ruminant using nitrogen fertilizer, limestone and sodium hypochlorite solutions
SMALL RUMINANT RESEARCH, 32(3), 197–204.
author keywords: gastrointestinal parasites; nitrogen fertilizers; bleach; limestone
TL;DR:
Gastrointestinal parasites are considered to be one of the most prominent health problems of small ruminants and additional concerns are associated with parasite resistance to traditional anthelmintics and drug withdrawal times.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
1999 journal article
Developmental arrest and pregnancy-induced transmammary transmission of Ancylostoma caninum larvae in the murine model
JOURNAL OF PARASITOLOGY, 85(5), 779–784.
TL;DR:
Significant numbers of larvae were not detected in mammary tissue during the periparturient or postpartum lactational periods although about 8% of a dam's reservoir of tissue larvae was transferred to her nursing pups, which suggests that larvae reaching the mammary glands are rapidly transmitted through the milk sinuses, as was documented by histopathological analyses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
1998 journal article
Anthelmintic efficacy against tissue-arrested larvae of Ancylostoma caninum in murine hosts
JOURNAL OF PARASITOLOGY, 84(6), 1263–1267.
TL;DR:
It is found that neither recommended nor elevated doses of commonly used anthelmintics were effective in eliminating latent infections with tissue-arrested hookworm larvae at the accepted standard of greater than 90% reduction in parasite burden.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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