Paul Wagner

College of Agriculture and Life Sciences

Works (1)

Updated: June 17th, 2023 22:42

2022 journal article

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype

Journal of Biomedical Materials Research Part A, 110(6), 1224–1237.

By: D. Chester n, V. Lee n, P. Wagner n, M. Nordberg n, M. Fisher n & A. Brown n

author keywords: loss tangent; mechanotransduction; microgel; viscoelasticity
MeSH headings : Biocompatible Materials / chemistry; Hydrogels / chemistry; Hydrogels / pharmacology; Mechanotransduction, Cellular / physiology; Phenotype; Viscosity
TL;DR: A novel composite hydrogel system capable of decoupling and individually controlling both the bulk stiffness and surface viscoelasticity of the material by combining polyacrylamide gels with microgel thin films is characterized, allowing for a greater understanding of cellular mechanotransduction mechanisms than previously possible through current model material platforms. (via Semantic Scholar)
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Added: February 7, 2022

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