Preston Gourville
College of Sciences
Works (1)
Updated: July 5th, 2023 15:21
2019 journal article
Aza-Amino Acids Disrupt -Sheet Secondary Structures
MOLECULES, 24(10).
author keywords: peptidomimetics; azapeptides; aza-amino acids; -hairpin; -sheet
MeSH headings : Amino Acid Sequence; Amino Acids / chemistry; Aza Compounds / chemistry; Aza Compounds / pharmacology; Hydrogen Bonding; Molecular Structure; Peptides / chemical synthesis; Peptides / chemistry; Protein Folding; Protein Structure, Secondary / drug effects; Proteins / chemistry; Solid-Phase Synthesis Techniques
TL;DR:
The effect of a single aza-amino acid incorporation located in the upper β-strand at a hydrogen-bonded (HB) site of a β-hairpin model peptide (H-Arg-Tyr-Val-Glu- Val-d-Pro-Gly-Orn-Lys-Ile-Leu-Gln-NH2) is reported.
(via Semantic Scholar)
open access via www.mdpi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
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Added: July 1, 2019
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