Works (6)

Updated: July 13th, 2023 21:14

2021 journal article

Monitoring of random microvessel network formation by in-line sensing of flow rates: A numerical and in vitro investigation


By: V. Pozdin*, P. Erb n, M. Downey n, K. Rivera n & M. Daniele n

author keywords: Microphysiological systems; Microfluidics; Equivalent circuit; Fluid mechanics; Vascular mechanics; Microvessels; Fluid networks
TL;DR: A strategy to monitor the dynamic formation of microscale fluid networks, which can be translated to the monitoring of microvasculature development in engineered tissue constructs and illustrates the potential to precisely and non-destructively monitor microvessel network development and volumetric changes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: October 18, 2021

2020 review

Editors' Choice-Critical Review-A Critical Review of Solid State Gas Sensors


By: G. Hunter*, S. Akbar*, S. Bhansali*, M. Daniele n, P. Erb n, K. Johnson*, C. Liu*, D. Miller* ...

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: June 22, 2020

2019 journal article

Integrated phosphorescence-based photonic biosensor (iPOB) for monitoring oxygen levels in 3D cell culture systems


By: K. Rivera n, V. Pozdin n, A. Young n, P. Erb n, N. Wisniewski*, S. Magness n, M. Daniele n

author keywords: Oxygen; Microdevice; Organs-on-chips; Oxygen biosensor; Biosensors; Hypoxia
MeSH headings : Biosensing Techniques; Cell Culture Techniques; Cell Hypoxia; Cell Line, Tumor; Humans; Luminescent Measurements / methods; Oxygen / chemistry; Oxygen / metabolism; Photons
TL;DR: The design and engineering of a system to remotely monitor and control oxygen concentration inside a device for 3D cell culture is reported, integrating a photonic oxygen biosensor into the 3D tissue scaffold and regulate oxygen concentration via the control of purging gas flow. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 3, 2018

2019 review

Measuring and regulating oxygen levels in microphysiological systems: design, material, and sensor considerations

[Review of ]. ANALYST, 144(10), 3190–3215.

By: K. Rivera n, M. Yokus n, P. Erb n, V. Pozdin n & M. Daniele n

MeSH headings : Animals; Cell Line; Humans; Lab-On-A-Chip Devices; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Models, Biological; Oxygen / analysis; Oxygen / metabolism
TL;DR: Comparisons of organ-specific MPS that do and do not consider oxygen microenvironments are offered and materials used in microphysiological models are analyzed in terms of their ability to control oxygen. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 22, 2019

2019 review

Monitoring of Microphysiological Systems: Integrating Sensors and Real-Time Data Analysis toward Autonomous Decision-Making

[Review of ]. ACS SENSORS, 4(6), 1454–1464.

By: A. Young n, K. Rivera n, P. Erb n & M. Daniele n

author keywords: microphysiological system (MPS); organ-on-chip; biosensor; real-time analysis; data; cyber-physical system
MeSH headings : Data Analysis; Humans; Lab-On-A-Chip Devices; Machine Learning; Microchip Analytical Procedures / methods; Monitoring, Physiologic / instrumentation; Monitoring, Physiologic / methods
TL;DR: In this Perspective, three stages of microphysiological system monitoring, including process, development, and function, are assessed and the unique features and remaining technical challenges for the required sensors are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: July 22, 2019

2018 journal article

Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction


By: T. Su n, K. Huang n, M. Daniele n, M. Hensley n, A. Young n, J. Tang n, T. Allen n, A. Vandergriff n ...

author keywords: microvessels; hydrodynamic focusing; cardiac stem cells; cardiomyocyte proliferation; angiogenesis; myocardial infarction
MeSH headings : Animals; Cells, Cultured; Female; Human Umbilical Vein Endothelial Cells; Humans; Microfluidic Analytical Techniques; Myocardial Infarction / therapy; Myocardium / cytology; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Neovascularization, Physiologic / physiology; Rats; Rats, Nude; Stem Cells / cytology; Stem Cells / physiology
TL;DR: It is shown that the endothelialized BMVs mimicked the natural architecture and function of capillaries and that the resultant vascularized cardiac patch (BMV-CSC patch) exhibited equivalent release of paracrine factors compared to those of coculture of genuine human CSCs and HUVECs after 7 days of in vitro culture. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 29, 2018

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