Paul Swartz

Gering, H. E., Li, X., Tang, H., Swartz, P. D., Chang, W.-C., & Makris, T. M. (2023). A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 8. https://doi.org/10.1021/jacs.3c04542

Schroder, G. C., William B. O'Dell, Swartz, P. D., & Meilleur, F. (2021). Preliminary results of neutron and X-ray diffraction data collection on a lytic polysaccharide monooxygenase under reduced and acidic conditions. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 77(4), 128–133. https://doi.org/10.1107/S2053230X21002399

Yao, L., Swartz, P., Hamilton, P. T., & Clark, A. C. (2021). Remodeling hydrogen bond Interactions results in relaxed specificity of Caspase-3. BIOSCIENCE REPORTS, 41(1). https://doi.org/10.1042/BSR20203495

Shrestha, S., Tung, J., Grinshpon, R. D., Swartz, P., Hamilton, P. T., Dimos, B., … Clark, A. C. (2020). Caspases from scleractinian coral show unique regulatory features. JOURNAL OF BIOLOGICAL CHEMISTRY, 295(43), 14578–14591. https://doi.org/10.1074/jbc.RA120.014345

Kearney, B. M., Schwabe, M., Marcus, K. C., Roberts, D. M., Dechene, M., Swartz, P., & Mattos, C. (2020). DRoP: Automated detection of conserved solvent-binding sites on proteins. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 88(1), 152–165. https://doi.org/10.1002/prot.25781

Agarwal, S., Smith, M., De La Rosa, I., Verba, K. A., Swartz, P., Segura-Totten, M., & Mattos, C. (2020). Development of a structure-analysis pipeline using multiple-solvent crystal structures of barrier-to-autointegration factor. ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY, 76, 1001–1014. https://doi.org/10.1107/S2059798320011341

Thomas, M. E., III, Grinshpon, R., Swartz, P., & Clark, A. C. (2018). Modifications to a common phosphorylation network provide individualized control in caspases. JOURNAL OF BIOLOGICAL CHEMISTRY, 293(15), 5447–5461. https://doi.org/10.1074/jbc.ra117.000728

Carey, L. M., Kim, K. B., McCombs, N. L., Swartz, P., Kim, C., & Ghiladi, R. A. (2018). Selective tuning of activity in a multifunctional enzyme as revealed in the F21W mutant of dehaloperoxidase B from Amphitrite ornata. JBIC Journal of Biological Inorganic Chemistry, 23(2), 209–219. https://doi.org/10.1007/s00775-017-1520-x

William B. O'Dell, Swartz, P. D., Weiss, K. L., & Meilleur, F. (2017). Crystallization of a fungal lytic polysaccharide monooxygenase expressed from glycoengineered Pichia pastoris for X-ray and neutron diffraction. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 73(2), 70–78. https://doi.org/10.1107/s2053230x16020318

Tucker, M. B., MacKenzie, S. H., Maciag, J. J., Dirscherl Ackerman, H., Swartz, P., Yoder, J. A., … Clay Clark, A. (2016). Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish. Protein Science, 25(11), 2076–2088. https://doi.org/10.1002/PRO.3032

Maciag, J. J., Mackenzie, S. H., Tucker, M. B., Schipper, J. L., Swartz, P., & Clark, A. C. (2016). Tunable allosteric library of caspase-3 identifies coupling between conserved water molecules and conformational selection. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 113(41), E6080–E6088. https://doi.org/10.1073/pnas.1603549113

Bodenheimer, A. M., Cuneo, M. J., Swartz, P. D., He, J., O'Neill, H. M., Myles, D. A., … Section, F. (2014). Crystallization and preliminary X-ray diffraction analysis of Hypocrea jecorina Cel7A in two new crystal forms. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 70(Pt 6), 773–776. https://doi.org/10.1107/s2053230x14008851

Kearney, B. N., Johnson, C. W., Roberts, D. M., Swartz, P., & Mattos, C. (2014). DRoP: A Water Analysis Program Identifies Ras-GTP-Specific Pathway of Communication between Membrane-Interacting Regions and the Active Site. JOURNAL OF MOLECULAR BIOLOGY, 426(3), 611–629. https://doi.org/10.1016/j.jmb.2013.10.036

Cade, C., Swartz, P., MacKenzie, S. H., & Clark, A. C. (2014). Modifying Caspase-3 Activity by Altering Allosteric Networks. BIOCHEMISTRY, 53(48), 7582–7595. https://doi.org/10.1021/bi500874k

MacKenzie, S. H., Schipper, J. L., England, E. J., Thomas, M. E., III, Blackburn, K., Swartz, P., & Clark, A. C. (2013). Lengthening the Intersubunit Linker of Procaspase 3 Leads to Constitutive Activation. BIOCHEMISTRY, 52(36), 6219–6231. https://doi.org/10.1021/bi400793s

Jiang, S., Wright, I., Swartz, P., & Franzen, S. (2013). The role of T56 in controlling the flexibility of the distal histidine in dehaloperoxidase-hemoglobin from Amphitrite ornata. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS, 1834(10), 2020–2029. https://doi.org/10.1016/j.bbapap.2013.06.005

Walters, J., Schipper, J. L., Swartz, P., Mattos, C., & Clark, A. C. (2012). Allosteric modulation of caspase 3 through mutagenesis. BIOSCIENCE REPORTS, 32(4), 401–411. https://doi.org/10.1042/bsr20120037

Walters, J., Swartz, P., Mattos, C., & Clark, A. C. (2011). Thermodynamic, enzymatic and structural effects of removing a salt bridge at the base of loop 4 in (pro)caspase-3. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 508(1), 31–38. https://doi.org/10.1016/j.abb.2011.01.011

Martin, S. L., Guenther, R. H., Sit, T. L., Swartz, P. D., Meilleur, F., Lommel, S. A., … Section, F. (2010). Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus. ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66(Pt 11), 1458–1462. https://doi.org/10.1107/s1744309110032483

Walters, J., Pop, C., Scott, F. L., Drag, M., Swartz, P., Mattos, C., … Clark, A. C. (2009). A constitutively active and uninhibitable caspase-3 zymogen efficiently induces apoptosis. BIOCHEMICAL JOURNAL, 424, 335–345. https://doi.org/10.1042/bj20090825

Dechene, M., Wink, G., Smith, M., Swartz, P., & Mattos, C. (2009). Multiple solvent crystal structures of ribonuclease A: An assessment of the method. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 76(4), 861–881. https://doi.org/10.1002/prot.22393

Feeney, B., Pop, C., Swartz, P., Mattos, C., & Clark, A. C. (2006). Role of loop bundle hydrogen bonds in the maturation and activity of (pro) caspase-3. BIOCHEMISTRY, 45(44), 13249–13263. https://doi.org/10.1021/bi0611964

Kundu, B., Richardson, S. D., Granville, C. A., Shaughnessy, D. T., Hanley, N. M., Swartz, P. D., … DeMarini, D. M. (2004). Comparative mutagenicity of halomethanes and halonitromethanes in Salmonella TA100: structure–activity analysis and mutation spectra. Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 554(1-2), 335–350. https://doi.org/10.1016/j.mrfmmm.2004.05.015

Kundu, B., Richardson, S. D., Swartz, P. D., Matthews, P. P., Richard, A. M., & DeMarini, D. M. (2004). Mutagenicity in Salmonella of halonitromethanes: a recently recognized class of disinfection by-products in drinking water. Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 562(1-2), 39–65. https://doi.org/10.1016/j.mrgentox.2004.05.007