Works (4)
Updated: July 5th, 2023 15:39
2021 journal article
Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone
JOURNAL OF BIOLOGICAL CHEMISTRY, 297(4).
MeSH headings : Acetylation; Animals; Caenorhabditis elegans / genetics; Caenorhabditis elegans / metabolism; Caenorhabditis elegans Proteins / genetics; Caenorhabditis elegans Proteins / metabolism; Histones / genetics; Histones / metabolism; Humans; Protein Binding; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
An essential function for the SWI/SNF bromodomain in vivo is demonstrated and potential redundancy in epigenetic readers in regulating chromatin remodeling is detected and have implications for the development of small-molecule BD inhibitors to treat cancers and other diseases.
(via Semantic Scholar)
open access via www.jbc.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 31, 2021
2021 journal article
Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase
BIOCHEMISTRY, 60(4), 324–345.
MeSH headings : Bacteria / enzymology; Bacterial Proteins / chemistry; Carbon-Nitrogen Ligases / chemistry; Crystallography, X-Ray; Enzyme Stability; Hot Temperature; Protein Domains; Structure-Activity Relationship
TL;DR:
Structural data reveal that the OGC BC dimer comprises a "wet" dimerization interface that is dominated by hydrophilic interactions and structural water molecules common to all BC domains and likely facilitates the conformational changes associated with the catalytic cycle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 20, 2021
2017 personal communication
GM-food regulations: engage the public
Enriquez, P. (2017, August 3).
MeSH headings : Food; Food, Genetically Modified; Humans; Plants, Genetically Modified; Public Opinion
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Gene-Specific Translation Regulation Mediated by the Hormone-Signaling Molecule EIN2
CELL, 163(3), 684–697.
Contributors: C. Merchante n, J. Brumos n, J. Yun n, Q. Hu n, K. Spencer n, n, B. Binder *, S. Heber n , A. Stepanova n , J. Alonso n
MeSH headings : 3' Untranslated Regions; Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; DNA-Binding Proteins; Ethylenes / metabolism; F-Box Proteins / genetics; Gene Expression Regulation, Plant; Nuclear Proteins / metabolism; Protein Biosynthesis; RNA, Messenger / metabolism; Receptors, Cell Surface / metabolism; Ribosomes / metabolism; Signal Transduction; Transcription Factors / metabolism
TL;DR:
Characterization of one of the targets of this translation regulatory machinery, the ethylene signaling component EBF2, indicates that the signaling molecule EIN2 and the nonsense-mediated decay proteins UPFs play a central role in this ethylene-induced translational response.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
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