Paul Orndorff

Tan, G. Z., Orndorff, P. E., & Shirwaiker, R. A. (2019). The Ion Delivery Manner Influences the Antimicrobial Efficacy of Silver Oligodynamic Iontophoresis. JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING, 39(4), 622–631. https://doi.org/10.1007/s40846-018-0447-1

Kuenemann, M. A., Spears, P. A., Orndorff, P. E., & Fourches, D. (2018). In silico predicted glucose-1-phosphate Uridylyltransferase (GalU) inhibitors block a key pathway required for Listeria virulence. Molecular Informatics, 37(6-7).

Tan, Z., Havell, E. A., Orndorff, P. E., & Shirwaiker, R. A. (2017). Antibacterial efficacy and cytotoxicity of low intensity direct current activated silver-titanium implant system prototype. BIOMETALS, 30(1), 113–125. https://doi.org/10.1007/s10534-017-9993-1

Tan, Z., Xu, G., Orndorff, P. E., & Shirwaiker, R. A. (2016). Effects of Electrically Activated Silver-Titanium Implant System Design Parameters on Time-Kill Curves Against Staphylococcus aureus. JOURNAL OF MEDICAL AND BIOLOGICAL ENGINEERING, 36(3), 325–333. https://doi.org/10.1007/s40846-016-0136-x

Cavanaugh, D. L., Tan, Z., Norris, J. P., Hardee, A., Weinhold, P. S., Dahners, L. E., … Shirwaiker, R. A. (2016). Evaluation of silver-titanium implants activated by low intensity direct current for orthopedic infection control: An in vitro and in vivo study. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 104(5), 1023–1031. https://doi.org/10.1002/jbm.b.33451

Spears, P. A., Havell, E. A., Hamrick, T. S., Goforth, J. B., Levine, A. L., Abraham, S. T., … Orndorff, P. E. (2016). Listeria monocytogenes wall teichoic acid decoration in virulence and cell-to-cell spread. MOLECULAR MICROBIOLOGY, 101(5), 714–730. https://doi.org/10.1111/mmi.13353

Orndorff, P. E. (2016). [Review of Use of bacteriophage to target bacterial surface structures required for virulence: a systematic search for antibiotic alternatives]. CURRENT GENETICS, 62(4), 753–757. https://doi.org/10.1007/s00294-016-0603-5

Fusco, W. G., Choudhary, N. R., Routh, P. A., Ventevogel, M. S., Smith, V. A., Koch, G. G., … Leduc, I. (2014). The Haemophilus ducreyi trimeric autotransporter adhesin DsrA protects against an experimental infection in the swine model of chancroid. VACCINE, 32(30), 3752–3758. https://doi.org/10.1016/j.vaccine.2014.05.031

Samberg, M. E., Tan, Z., Monteiro-Riviere, N. A., Orndorff, P. E., & Shirwaiker, R. A. (2013). Biocompatibility analysis of an electrically-activated silver-based antibacterial surface system for medical device applications. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 24(3), 755–760. https://doi.org/10.1007/s10856-012-4838-5

Tan, Z., Shirwaiker, R., & Orndoff, P. E. (2013). Determining optimal current intensity and duration for electrically activated silver-based prophylactic hip implant prototype design. ASME 2013 Summer Bioengineering Conference, SBC 2013, 1 B. https://doi.org/10.1115/sbc2013-14141

Suyemoto, M. M., Hamrick, T. S., Spears, P. A., Horton, J. R., Washington, I. M., Havell, E. A., … Orndorff, P. E. (2013). Extrauterine Listeriosis in the gravid mouse influences embryonic growth and development. PLoS One, 8(8).

Samberg, M. E., Orndorff, P. E., & Monteiro-Riviere, N. A. (2011). Antibacterial efficacy of silver nanoparticles of different sizes, surface conditions and synthesis methods. NANOTOXICOLOGY, 5(2), 244–253. https://doi.org/10.3109/17435390.2010.525669

Spears, P. A., Suyemoto, M. M., Hamrick, T. S., Wolf, R. L., Havell, E. A., & Orndorff, P. E. (2011). In Vitro Properties of a Listeria monocytogenes Bacteriophage-Resistant Mutant Predict Its Efficacy as a Live Oral Vaccine Strain. INFECTION AND IMMUNITY, 79(12), 5001–5009. https://doi.org/10.1128/iai.05700-11

Lee, Y.-H., Su, K.-Y., Wyse, A., Barbas, A., Palestrandt, D., Shieh, K., … Parker, W. (2011). Incorporation of secretory immunoglobulin A into biofilms can decrease their resistance to ciprofloxacin. MICROBIOLOGY AND IMMUNOLOGY, 55(3), 174–183. https://doi.org/10.1111/j.1348-0421.2010.00297.x

Leduc, I., Fusco, W. G., Choudhary, N., Routh, P. A., Cholon, D. M., Hobbs, M. M., … Elkins, C. (2011). Passive Immunization with a Polyclonal Antiserum to the Hemoglobin Receptor of Haemophilus ducreyi Confers Protection against a Homologous Challenge in the Experimental Swine Model of Chancroid. INFECTION AND IMMUNITY, 79(8), 3168–3177. https://doi.org/10.1128/iai.00017-11

Lee, S. M., Wyse, A., Lesher, A., Everett, M. L., Lou, L., Holzknecht, Z. E., … Parker, W. (2010). Adaptation in a Mouse Colony Monoassociated with Escherichia coli K-12 for More than 1,000 Days. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(14), 4655–4663. https://doi.org/10.1128/aem.00358-10

Suyemoto, M. M., Spears, P. A., Hamrick, T. S., Barnes, J. A., Havell, E. A., & Orndorff, P. E. (2010). Factors Associated with the Acquisition and Severity of Gestational Listeriosis. PLOS ONE, 5(9). https://doi.org/10.1371/journal.pone.0013000

Temple, L. M., Miyamoto, D. M., Mehta, M., Capitini, C. M., Von Stetina, S., Barnes, H. J., … Orndorff, P. E. (2010). Identification and Characterization of Two Bordetella avium Gene Products Required for Hemagglutination. INFECTION AND IMMUNITY, 78(6), 2370–2376. https://doi.org/10.1128/iai.00140-10

Fusco, W. G., Afonina, G., Nepluev, I., Cholon, D. M., Choudhary, N., Routh, P. A., … Elkins, C. (2010). Immunization with the Haemophilus ducreyi Hemoglobin Receptor HgbA with Adjuvant Monophosphoryl Lipid A Protects Swine from a Homologous but Not a Heterologous Challenge. INFECTION AND IMMUNITY, 78(9), 3763–3772. https://doi.org/10.1128/iai.00217-10

Barbas, A. S., Lesher, A. P., Thomas, A. D., Wyse, A., Devalapalli, A. P., Lee, Y.-H., … Parker, W. (2009). Altering and Assessing Persistence of Genetically Modified E. coli MG1655 in the Large Bowel. EXPERIMENTAL BIOLOGY AND MEDICINE, 234(10), 1174–1185. https://doi.org/10.3181/0812-RM-358

Zhu, X.-Y., Holtz, B., Wang, Y., Wang, L.-X., Orndorff, P. E., & Guo, A. (2009). Quantitative Glycomics from Fluidic Glycan Microarrays. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(38), 13646–13650. https://doi.org/10.1021/ja902783n

Spears, P. A., Suyemoto, M. M., Palermo, A. M., Horton, J. R., Hamrick, T. S., Havell, E. A., & Orndorff, P. E. (2008). A Listeria monocytogenes mutant defective in bacteriophage attachment is attenuated in orally inoculated mice and impaired in enterocyte intracellular growth. INFECTION AND IMMUNITY, 76(9), 4046–4054. https://doi.org/10.1128/IAI.00283-08

Sebaihia, M., & Orndorff, P. E. (2006). Comparison of the genome sequence of the poultry pathogen Bordetella avium with those of B-bronchiseptica, B-pertussis, and B-parapertussis reveals extensive diversity in surface structures associated with host interaction. Journal of Bacteriology, 188(16), 6002–6015.

Fulcher, R. A., Cole, L. E., Janowicz, D. M., Toffer, K. L., Fortney, K. R., Katz, B. P., … Kawula, T. H. (2006). Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid. INFECTION AND IMMUNITY, 74(5), 2651–2658. https://doi.org/10.1128/IAI.74.5.2651-2658.2006

Orndorff, P. E., Hamrick, T. S., Smoak, I. W., & Havell, E. A. (2006). [Review of Host and bacterial factors in listeriosis pathogenesis]. VETERINARY MICROBIOLOGY, 114(1-2), 1–15. https://doi.org/10.1016/j.vetmic.2005.12.003

Afonina, G., Leduc, I., Nepluev, I., Jeter, C., Routh, P., Almond, G., … Elkins, C. (2006). Immunization with the Haemophilus ducreyi hemoglobin receptor HgbA protects against infection in the swine model of chancroid. INFECTION AND IMMUNITY, 74(4), 2224–2232. https://doi.org/10.1128/IAI.74.4.2224-2232.2006

Bollinger, R. R., Everett, M. L., Wahl, S. D., Lee, Y. H., Orndorff, P. E., & Parker, W. (2006). Secretory IgA and mucin-mediated biofilm formation by environmental strains of Escherichia coli: role of type 1 pili. MOLECULAR IMMUNOLOGY, 43(4), 378–387. https://doi.org/10.1016/j.molimm.2005.02.013

Orndorff, P. E., Devapali, A., Palestrant, S., Wyse, A., Everett, M. L., Bollinger, R. R., & Parker, W. (2004). Immunoglobulin-mediated agglutination of and biofilm formation by Escherichia coli K-12 require the type 1 pilus fiber. INFECTION AND IMMUNITY, 72(4), 1929–1938. https://doi.org/10.1128/IAI.72.4.1929-1938.2004

Cole, L. E., Toffer, K. L., Fulcher, R. A., San Mateo, L. R., Orndorff, P. E., & Kawula, T. H. (2003). A humoral immune response confers protection against Haemophilus ducreyi infection. INFECTION AND IMMUNITY, 71(12), 6971–6977. https://doi.org/10.1128/IAI.71.12.6971-6977.2003

Hamrick, T. S., Diaz, A. H., Havell, E. A., Horton, JR, & Orndorff, P. E. (2003). Influence of extracellular bactericidal agents on bacteria within macrophages. INFECTION AND IMMUNITY, 71(2), 1016–1019. https://doi.org/10.1128/IAI.71.2.1016-1019.2003

Hamrick, T. S., Horton, JR, Spears, P. A., Havell, E. A., Smoak, I. W., & Orndorff, P. E. (2003). Influence of pregnancy on the pathogenesis of listeriosis in mice inoculated intragastrically. INFECTION AND IMMUNITY, 71(9), 5202–5209. https://doi.org/10.1128/IAI.71.9.5202-5209.2003

Valenski, M. L., Harris, S. L., Spears, P. A., Horton, JR, & Orndorff, P. E. (2003). The product of the fimI gene is necessary for Escherichia coli type 1 pilus biosynthesis. JOURNAL OF BACTERIOLOGY, 185(16), 5007–5011. https://doi.org/10.1128/JB.185.16.5007-5011.2003

Spears, P. A., Temple, L. M., Miyamoto, D. M., Maskell, D. J., & Orndorff, P. E. (2003). Unexpected similarities between Bordetella avium and other pathogenic bordetellae. INFECTION AND IMMUNITY, 71(5), 2591–2597. https://doi.org/10.1128/IAI.71.5.2591-2597.2003

Murphy, E. R., Sacco, R. E., Dickenson, A., Metzger, D. J., Hu, Y., Orndorff, P. E., & Connell, T. D. (2002). BhuR, a virulence-associated outer membrane protein of Bordetella avium, is required for the acquisition of iron from heme and hemoproteins. INFECTION AND IMMUNITY, 70(10), 5390–5403. https://doi.org/10.1128/IAI.70.10.5390-5403.2002

Shelton, C. B., Temple, L. M., & Orndorff, P. E. (2002). Use of bacteriophage Ba1 to identify properties associated with Bordetella avium virulence. Infection and Immunity, 70(3), 1219–1224. https://doi.org/10.1128/IAI.70.3.121901224.2002

Harris, S. L., Spears, P. A., Havell, E. A., Hamrick, T. S., Horton, JR, & Orndorff, P. E. (2001). Characterization of Escherichia coli type 1 pilus mutants with altered binding specificities. JOURNAL OF BACTERIOLOGY, 183(13), 4099–4102. https://doi.org/10.1128/JB.183.13.4099-4102.2001

Lu, J., Hill, M. A., Hood, M., Greeson, D. F., Horton, J. R., Orndorff, P. E., … Tonelli, A. E. (2001). Formation of antibiotic, biodegradable polymers by processing with Irgasan DP300R (Triclosan) and its inclusion compound with beta-cyclodextrin. Journal of Applied Polymer Science, 82(2), 300–309. https://doi.org/10.1002/app.1852.abs

Spears, P. A., Temple, L. M., & Orndorff, P. E. (2000). A role for lipopolysaccharide in turkey tracheal colonization by Bordetella avium as demonstrated in vivo and in vitro. MOLECULAR MICROBIOLOGY, 36(6), 1425–1435. https://doi.org/10.1046/j.1365-2958.2000.01963.x

Ryan, JR, Apperson, C. S., Orndorff, P. E., & Levine, J. F. (2000). Characterization of Lyme disease spirochetes isolated from ticks and vertebrates in North Carolina. JOURNAL OF WILDLIFE DISEASES, 36(1), 48–55. https://doi.org/10.7589/0090-3558-36.1.48

Shelton, C. B., Crosslin, D. R., Casey, J. L., Ng, S., Temple, L. M., & Orndorff, P. E. (2000). Discovery, purification, and characterization of a temperate transducing bacteriophage for Bordetella avium. JOURNAL OF BACTERIOLOGY, 182(21), 6130–6136. https://doi.org/10.1128/JB.182.21.6130-6136.2000

Metcalf, E. S., Almond, G. W., Routh, P. A., Horton, JR, Dillman, R. C., & Orndorff, P. E. (2000). Experimental Salmonella typhi infection in the domestic pig, Sus scrofa domestica. MICROBIAL PATHOGENESIS, 29(2), 121–126. https://doi.org/10.1006/mpat.2000.0367

Hamrick, T. S., Harris, S. L., Spears, P. A., Havell, E. A., Horton, JR, Russell, P. W., & Orndorff, P. E. (2000). Genetic characterization of Escherichia coli type 1 pilus adhesin mutants and identification of a novel binding phenotype. JOURNAL OF BACTERIOLOGY, 182(14), 4012–4021. https://doi.org/10.1128/JB.182.14.4012-4021.2000

Hamrick, T. S., Havell, E. A., Horton, JR, & Orndorff, P. E. (2000). Host and bacterial factors involved in the innate ability of mouse macrophages to eliminate internalized unopsonized Escherichia coli. INFECTION AND IMMUNITY, 68(1), 125–132. https://doi.org/10.1128/IAI.68.1.125-132.2000

Huang, L., Taylor, H., Gerber, M., Orndorff, P. E., Horton, JR, & Tonelli, A. (1999). Formation of antibiotic, biodegradable/bioabsorbable polymers by processing with neomycin sulfate and its inclusion compound with beta-cyclodextrin. JOURNAL OF APPLIED POLYMER SCIENCE, 74(4), 937–947. https://doi.org/10.1002/(SICI)1097-4628(19991024)74:4<937::AID-APP20>3.0.CO;2-K

San Mateo, L. R., Toffer, K. L., Orndorff, P. E., & Kawula, T. H. (1999). Immune cells are required for cutaneous ulceration in a swine model of chancroid. Infection and Immunity, 67(9), 4963–4967.

San Mateo, L. R., Toffer, K. L., Orndorff, P. E., & Kawula, T. H. (1999). Neutropenia restores virulence to an attenuated Cu,Zn superoxide dismutase-deficient Haemophilus ducreyi strain in the swine model of chancroid. Infection and Immunity, 67(10), 5345–5351.

Ryan, JR, Levine, J. F., Apperson, C. S., Lubke, L., Wirtz, R. A., Spears, P. A., & Orndorff, P. E. (1998). An experimental chain of infection reveals that distinct Borrelia burgdorferi populations are selected in arthropod and mammalian hosts. MOLECULAR MICROBIOLOGY, 30(2), 365–379. https://doi.org/10.1046/j.1365-2958.1998.01071.x

Temple, L. M., Weiss, A. A., Walker, K. E., Barnes, H. J., Christensen, V. L., Miyamoto, D. M., … Orndorff, P. E. (1998). Bordetella avium virulence measured in vivo and in vitro. Infection and Immunity, 66(11), 5244–5251.

Maurelli, A. T., Routh, P. R., Dillman, R. C., Ficken, M. D., Weinstock, D. M., Almond, G. W., & Orndorff, P. E. (1998). Shigella infection as observed in the experimentally inoculated domestic pig, Sus scrofa domestica. MICROBIAL PATHOGENESIS, 25(4), 189–196. https://doi.org/10.1006/mpat.1998.0230