Works (8)

Updated: July 5th, 2023 21:21

2021 journal article

Integrative structural dynamics probing of the conformational heterogeneity in synaptosomal-associated protein 25

CELL REPORTS PHYSICAL SCIENCE, 2(11).

By: N. Saikia*, I. Yanez-Orozco*, R. Qiu n, P. Hao n, S. Milikisiyants n, E. Ou n, G. Hamilton*, K. Weninger n ...

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: March 14, 2022

2021 journal article

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

JOURNAL OF BIOLOGICAL CHEMISTRY, 297(3).

By: H. Pan n, P. Kaur n, R. Barnes*, A. Detwiler*, S. Sanford*, M. Liu n, P. Xu n, C. Mahn n ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Cell Adhesion Molecules / metabolism; Cell Adhesion Molecules / physiology; DNA / metabolism; DNA-Binding Proteins / metabolism; Humans; Microscopy, Atomic Force / methods; Models, Molecular; Multiprotein Complexes / metabolism; Protein Binding; Protein Isoforms / metabolism; Shelterin Complex / metabolism; Shelterin Complex / physiology; Telomere / metabolism; Telomere-Binding Proteins / metabolism; Telomere-Binding Proteins / physiology; Telomeric Repeat Binding Protein 1 / metabolism; Telomeric Repeat Binding Protein 1 / physiology; Telomeric Repeat Binding Protein 2 / metabolism; Telomeric Repeat Binding Protein 2 / physiology
Sources: Web Of Science, ORCID
Added: October 26, 2021

2020 journal article

Dynamic human MutS alpha-MutL alpha complexes compact mismatched DNA

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(28), 16302–16312.

By: K. Bradford*, H. Wilkins*, P. Hao n, Z. Li*, B. Wang*, D. Burke*, D. Wu*, A. Smith* ...

co-author countries: United States of America 🇺🇸
author keywords: DNA repair; AFM; MutS; MutL; DREEM
MeSH headings : Adenosine Triphosphate / metabolism; DNA / chemistry; DNA / genetics; DNA / metabolism; DNA Mismatch Repair; DNA-Binding Proteins / chemistry; DNA-Binding Proteins / metabolism; Humans; Multiprotein Complexes / metabolism; MutL Proteins / chemistry; MutL Proteins / metabolism; MutS Homolog 2 Protein / chemistry; MutS Homolog 2 Protein / metabolism; Nucleic Acid Conformation; Nucleosomes / metabolism; Protein Folding; Protein Multimerization
Sources: Web Of Science, ORCID
Added: August 17, 2020

2020 journal article

Recurrent mismatch binding by MutS mobile clamps on DNA localizes repair complexes nearby

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 117(30), 17775–17784.

By: P. Hao n, S. LeBlanc n, B. Case*, T. Elston*, M. Hingorani*, D. Erie*, K. Weninger n

co-author countries: United States of America 🇺🇸
author keywords: smFRET; MMR; mismatch repair; MutS
MeSH headings : Adenosine Triphosphatases / metabolism; Adenosine Triphosphate / metabolism; Base Pair Mismatch; DNA / chemistry; DNA / genetics; DNA / metabolism; DNA Mismatch Repair; Hydrolysis; Models, Molecular; Multiprotein Complexes / metabolism; MutL Proteins / chemistry; MutL Proteins / metabolism; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / metabolism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 17, 2020

2018 journal article

Coordinated protein and DNA conformational changes govern mismatch repair initiation by MutS

NUCLEIC ACIDS RESEARCH, 46(20), 10782–10795.

By: S. LeBlanc n, J. Gauer*, P. Hao n, B. Case*, M. Hingorani*, K. Weninger n, D. Erie*

co-author countries: United States of America 🇺🇸
MeSH headings : Base Pair Mismatch / genetics; Base Pairing / physiology; DNA / chemistry; DNA Mismatch Repair / genetics; Escherichia coli; Fluorescence Resonance Energy Transfer; Genomic Instability / genetics; Models, Molecular; MutS DNA Mismatch-Binding Protein / chemistry; MutS DNA Mismatch-Binding Protein / genetics; MutS DNA Mismatch-Binding Protein / metabolism; Mutant Proteins / chemistry; Mutant Proteins / metabolism; Nucleic Acid Conformation; Protein Binding / physiology; Protein Conformation; Protein Domains / genetics; Protein Isoforms / chemistry; Protein Isoforms / genetics; Protein Isoforms / metabolism
Sources: Web Of Science, ORCID
Added: February 11, 2019

2018 journal article

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

NATURE METHODS, 15(9), 669-+.

By: B. Hellenkamp*, S. Schmid*, O. Doroshenko*, O. Opanasyuk*, R. Kuehnemuth, S. Adariani*, B. Ambrose*, M. Aznauryan* ...

co-author countries: Belgium 🇧🇪 Switzerland 🇨🇭 Germany 🇩🇪 Denmark 🇩🇰 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Korea (Republic of) 🇰🇷 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Fluorescence Resonance Energy Transfer / methods; Laboratories / standards; Reproducibility of Results
Sources: Web Of Science, ORCID
Added: October 19, 2018

2017 journal article

Phosphorylation-induced conformational dynamics in an intrinsically disordered protein and potential role in phenotypic heterogeneity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 114(13), E2644–E2653.

By: P. Kulkarni*, M. Jolly*, D. Jia*, S. Mooney*, A. Bhargava, L. Kagohara*, Y. Chen*, P. Hao n ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: intrinsic disorder; androgen resistance; prostate cancer; PAGE-4; phenotypic heterogeneity
MeSH headings : Antigens, Neoplasm / chemistry; Antigens, Neoplasm / metabolism; Humans; Intrinsically Disordered Proteins / chemistry; Intrinsically Disordered Proteins / metabolism; Models, Molecular; Phenotype; Phosphorylation; Protein Conformation; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Protein Serine-Threonine Kinases / physiology; Protein-Tyrosine Kinases / genetics; Protein-Tyrosine Kinases / metabolism; Protein-Tyrosine Kinases / physiology; Proteome
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Single-molecule FRET to measure conformational dynamics of DNA mismatch repair proteins

Single-Molecule Enzymology: Fluorescence-Based and High-Throughput Methods, 581, 285–315.

By: J. Gauer, S. LeBlanc, P. Hao, R. Qiu, B. Case, M. Sakato, M. Hingorani, D. Erie, K. Weninger

Source: NC State University Libraries
Added: August 6, 2018