Works (3)
Updated: July 5th, 2023 15:38
2017 journal article
Engineering 3D-Bioplotted scaffolds to induce aligned extracellular matrix deposition for musculoskeletal soft tissue replacement
CONNECTIVE TISSUE RESEARCH, 58(3-4), 342–354.
Contributors: P. Warren n, P. Huebner n, J. Spang*, R. Shirwaiker n & M. Fisher n
author keywords: Biofabrication; meniscus; tissue engineering; scaffold; 3D printing
MeSH headings : Animals; Cell Count; Cell Shape; Collagen / metabolism; Extracellular Matrix / metabolism; Imaging, Three-Dimensional; Male; Musculoskeletal Physiological Phenomena; Rats, Sprague-Dawley; Regeneration / physiology; Sus scrofa; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR:
The ability to use interstrand spacing as a means of controlling the formation of aligned collagen in vivo was demonstrated, which helps establish a design space for scaffold-based meniscus tissue engineering.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2017 journal article
Fabrication and Evaluation of Electrospun, 3D-Bioplotted, and Combination of Electrospun/3D-Bioplotted Scaffolds for Tissue Engineering Applications
BIOMED RESEARCH INTERNATIONAL, 2017.
Contributors: L. Mellor n, P. Huebner n, S. Cai n, M. Mohiti-Asli n, M. Taylor n, J. Spang*, R. Shirwaiker n , E. Loboa*
MeSH headings : Animals; Cells, Cultured; Extracellular Matrix / chemistry; Humans; Nanofibers / chemistry; Nanofibers / therapeutic use; Polyesters / chemistry; Polyesters / therapeutic use; Porosity; Printing, Three-Dimensional; Swine; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR:
The approach combining these two commonly used scaffold fabrication technologies allows for the creation of a scaffold with more close resemblance to heterogeneous tissue architecture, holding great potential for tissue engineering and regenerative medicine applications of osteochondral tissue and other heterogeneous tissues.
(via Semantic Scholar)
downloads.hindawi.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2016 journal article
3D-Bioprinting of Polylactic Acid (PLA) Nanofiber–Alginate Hydrogel Bioink Containing Human Adipose-Derived Stem Cells
ACS Biomaterials Science & Engineering, 2(10), 1732–1742.
Contributors: L. Narayanan n, P. Huebner n, M. Fisher n, J. Spang*, B. Starly n & R. Shirwaiker n
author keywords: bioprinting; knee meniscus; alginate; nanofibers; adipose-derived stem cells; musculoskeletal soft tissue
TL;DR:
This study focuses on the development and proof-of-concept assessment of a fibrous bioink composed of alginate hydrogel, polylactic acid nanofibers, and human adipose-derived stem cells for bioprinting such tissue constructs and shows that the nanofiber-reinforced bioink allowed higher levels of cell proliferation within biopprinted strands.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
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