Works (13)

2022 journal article

A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures

TOXICS, 10(8).

By: L. Ford*, S. Jang, Z. Chen, Y. Zhou, P. Gallins, F. Wright, W. Chiu, I. Rusyn

author keywords: population-wide; inter-individual variability; toxicodynamics; chemical mixtures; defined mixtures; human health risk assessment; uncertainty factors; genome-wide association study
Sources: Web Of Science, ORCID
Added: August 2, 2022

2022 journal article

A resource for integrated genomic analysis of the human liver

SCIENTIFIC REPORTS, 12(1).

By: Y. Zhou, P. Gallins, A. Etheridge*, D. Jima, E. Scholl, F. Wright, F. Innocenti*

Sources: Web Of Science, ORCID
Added: September 8, 2022

2022 journal article

Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

AMERICAN JOURNAL OF HUMAN GENETICS, 109(9), 1638–1652.

By: C. Harlow, J. Gandawijaya, R. Bamford, E. Martin, A. Wood, P. Most, T. Tanaka, H. Leonard ...

Source: Web Of Science
Added: November 21, 2022

2022 journal article

Leveraging TOPMed imputation server and constructing a cohort-specific imputation reference panel to enhance genotype imputation among cystic fibrosis patients

HUMAN GENETICS AND GENOMICS ADVANCES, 3(2).

By: Q. Sun*, W. Liu*, J. Rosen*, L. Huang*, R. Pace*, H. Dang*, P. Gallins, E. Blue ...

Sources: Web Of Science, ORCID
Added: May 10, 2022

2020 journal article

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes

CLINICAL PHARMACOLOGY & THERAPEUTICS, 107(6), 1383–1393.

By: A. Etheridge*, P. Gallins, D. Jima, K. Broadaway*, M. Ratain*, E. Schuetz*, E. Schadt*, A. Schroder* ...

Sources: Web Of Science, ORCID
Added: February 10, 2020

2020 journal article

Exploring the Limits of Combined Image/'omics Analysis for Non-cancer Histological Phenotypes

FRONTIERS IN GENETICS, 11.

By: P. Gallins, E. Saghapour & Y. Zhou

author keywords: imaging; genomics; pathology; prediction; integration; histology; machine learning; embedding
Sources: Web Of Science, ORCID
Added: November 24, 2020

2019 review

A Review and Tutorial of Machine Learning Methods for Microbiome Host Trait Prediction

[Review of ]. FRONTIERS IN GENETICS, 10.

By: Y. Zhou & P. Gallins

author keywords: disease; phenotype; modeling; machine learning; prediction
Sources: Web Of Science, ORCID
Added: July 15, 2019

2018 journal article

A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Cell Reports, 23(2), 327–336.

By: T. Frayling, R. Beaumont, S. Jones, H. Yaghootkar, M. Tuke, K. Ruth, F. Casanova, B. West ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

A zero-inflated beta-binomial model for microbiome data analysis

STAT, 7(1).

By: T. Hu, P. Gallins & Y. Zhou

author keywords: count data; penalized generalized linear model; zero-inflated beta-binomial modelling
Sources: NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Airway mucosal host defense is key to genomic regulation of cystic fibrosis lung disease severity

American Journal of Respiratory and Critical Care Medicine, 197(1), 79–93.

By: D. Polineni, H. Dang, P. Gallins, L. Jones, R. Pace, J. Stonebraker, L. Commander, J. Krenicky ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Genomic Characterization of Metformin Hepatic Response

PLOS GENETICS, 12(11).

Source: Web Of Science
Added: August 6, 2018

2016 conference paper

Poster: risk-based attack surface approximation

Symposium and Bootcamp on the Science of Security, 121–123.

By: C. Theisen & L. Williams

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

ENVIRONMENTAL HEALTH PERSPECTIVES, 123(5), 458–466.

By: N. Abdo*, M. Xia*, C. Brown, O. Kosyk*, R. Huang*, S. Sakamuru*, Y. Zhou, J. Jack ...

Source: Web Of Science
Added: August 6, 2018