Pradeep Neupane

Works (10)

Updated: February 12th, 2024 13:56

2024 article

Diagnostic challenge in veterinary pathology: Tri-cavitary effusion in a cat with systemic pyogranulomatous inflammation

Fingerhood, S., Neupane, P., Breitschwerdt, E. B., & Choi, E. A. (2024, January 21). VETERINARY PATHOLOGY, Vol. 1.

By: S. Fingerhood *, P. Neupane n, E. Breitschwerdt n  & E. Choi *

UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 29, 2024

2023 journal article

Feeding on a Bartonella henselae Infected Host Triggers Temporary Changes in the Ctenocephalides felis Microbiome

PATHOGENS, 12(3).

By: C. Moore  n, E. Lashnits n , P. Neupane n, B. Herrin*, M. Lappin *, M. Andre *, E. Breitschwerdt n 

author keywords: Bartonella henselae; Ctenocephalides felis; flea; microbiome; wolbachia; vector microbiome
TL;DR: Using Next Generation Sequencing (NGS) on the Illumina platform, an increase in microbial diversity in C. felis microbiome when fed on B. henselae-infected cats is documented, which may be related to the mammalian, flea, or endosymbiont response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 23, 2023

2022 journal article

Bartonella henselae Recombinant Pap31 for the Diagnosis of Canine and Human Bartonelloses

PATHOGENS, 11(2).

By: P. Neupane n, R. Maggi n , M. Basnet *, E. Lashnits* , G. Andrews* & E. Breitschwerdt n 

author keywords: antigen; Bartonella henselae; serology; diagnosis; ELISA; Western blot; heme binding proteins
TL;DR: It is indicated that recombinant Pap31 and the selected fragments may not be appropriate diagnostic targets in detecting anti-Bartonella antibodies in Bartonella-infected dogs and humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 2, 2022

2022 journal article

Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12.

By: M. Andre  n, P. Neupane n, M. Lappin *, B. Herrin*, V. Smith*, T. Williams n , L. Collins n , H. Bai n ...

Contributors: M. André  n, P. Neupane n, M. Lappin *, B. Herrin*, V. Smith*, T. Williams n , L. Collins n , H. Bai n ...

author keywords: bartonellosis; cat flea; cat scratch disease; flea-pathogen interface; proteome
MeSH headings : Animals; Bartonella henselae / genetics; Cat Diseases; Cats; Ctenocephalides; Felis; Proteomics; Siphonaptera
TL;DR: Flea-differentially abundant proteins (FDAP) are investigated in unfed fleas, fleas fed on uninfected cats, and flea fed on B. henselae-infected cats to help understand the complex interactions between cat fleas and B. Henselae over an infection time course, thus helping understand the dual effect of vaccine targeting both flea fitness and pathogen competence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 29, 2022

2021 article

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States

Lashnits, E., Thatcher, B., Carruth, A., Mestek, A., Buch, J., Beall, M., … Breitschwerdt, E. B. (2021, November 17). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 36.

By: E. Lashnits n , B. Thatcher*, A. Carruth*, A. Mestek*, J. Buch *, M. Beall *, P. Neupane n, R. Chandrashekar *, E. Breitschwerdt n 

author keywords: bartonellosis; canine; seroreactivity; vector-borne; zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dogs; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Demographic and geographic findings for Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 18, 2021

2021 journal article

Comparison of Serological and Molecular Assays for Bartonella Species in Dogs with Hemangiosarcoma

PATHOGENS, 10(7).

By: E. Lashnits n , P. Neupane n, J. Bradley n, T. Richardson n, R. Maggi n  & E. Breitschwerdt n 

author keywords: diagnostic testing; ddPCR; PCR; serology; sensitivity; specificity; tissue biopsy; latent class analysis
TL;DR: Data indicate that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 24, 2021

2020 journal article

Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs

JOURNAL OF CLINICAL MICROBIOLOGY, 58(4).

By: P. Neupane n, S. Sevala n, N. Balakrishnan*, H. Marr n, J. Wilson n, R. Maggi n , A. Birkenheuer n , M. Lappin *, B. Chomel *, E. Breitschwerdt n 

author keywords: serology; zoonosis; vector borne; Western blotting; antigen; Bartonella henselae
MeSH headings : Animals; Antibodies, Bacterial; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae; Blotting, Western; Dog Diseases / diagnosis; Dogs; Serologic Tests
TL;DR: This study characterized WB immunodominant proteins that could be used to confirm a serodiagnosis of canine bartonelloses using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell proteins, and found a strong but variable recognition of these proteins among 81% of group II dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020

2018 journal article

Bartonella henselae in a dog with ear tip vasculitis

Veterinary Dermatology, 29(6), 537–e180.

By: B. Southern n, P. Neupane n, M. Ericson *, J. Dencklau*, K. Linder n, J. Bradley n, G. McKeon n, C. Long*, E. Breitschwerdt n 

MeSH headings : Animals; Bartonella henselae / genetics; Cat-Scratch Disease / pathology; Cat-Scratch Disease / veterinary; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Ear, External / microbiology; Ear, External / pathology; Female; Polymerase Chain Reaction / veterinary; Vasculitis / diagnosis; Vasculitis / pathology; Vasculitis / veterinary
TL;DR: Bartonella henselae is an emerging zoonotic pathogen that has been associated with leucocytoclastic vasculitis in humans and may have had a contributing or causative role in the development of the cutaneous aural margin vasculopathy in this beagle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs

Journal of Veterinary Internal Medicine, 32(6), 1958–1964.

By: P. Neupane n, B. Hegarty n, H. Marr n, R. Maggi n , A. Birkenheuer n  & E. Breitschwerdt n 

author keywords: bacteria; BAPGM; serology; vector-borne; zoonosis
MeSH headings : Animals; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella quintana / immunology; Cells, Cultured; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique / methods; Fluorescent Antibody Technique / veterinary; Polymerase Chain Reaction / veterinary; Sensitivity and Specificity; Serologic Tests / methods; Serologic Tests / veterinary; Trench Fever / diagnosis; Trench Fever / veterinary
TL;DR: Despite IFA testing of dogs against 8 different Bartonella isolates, IFA sensitivity remained poor, and specificity was only 85%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: December 31, 2018

2018 journal article

Pasteurella canis infective endocarditis in a dog

Veterinary Microbiology, 229, 14–19.

By: Z. Kern n, O. Swartley n, P. Neupane n, N. Balakrishnan n & E. Breitschwerdt n 

author keywords: Pasteurella cards; Infective vegetative endocarditis; Sepsis; Vasculitis; 16S rDNA PCR; MAIDLTOF
MeSH headings : Animals; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Fatal Outcome; Male; Pasteurella / classification; Pasteurella Infections / microbiology; Pasteurella Infections / veterinary
TL;DR: The goal of this study is to detail the clinical presentation and microbiological findings associated with a novel causative agent of infective endocarditis in the dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 18, 2019

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