Paul R Hess

855 Interim results from a comparative oncology safety study evaluating intravesical chitosan/interleukin-12 immunotherapy in client-owned dogs with invasive urothelial carcinoma

Helein, G. T., Nguyen, T. T., Intile, J. L., Mastromauro, M. L., Vaden, S. A., Hess, P. R., & Zaharoff, D. A. (2025, November 1). Regular and Young Investigator Award Abstracts, Vol. 11.

Assessing mutation-origin neopeptide prediction tools in canine cancer using the model MHC class Ia allomorphs, DLA-88*508:01 and *034:01 9302

Hess, P. R., Lee, C.-Y., Holmes, J., & Zaharoff, D. (2025, November 1). The Journal of Immunology.

Immunological responses and clinical outcomes in dogs with osteosarcoma receiving standard therapy and a Listeria vaccine expressing HER2

Mason, N. J., Selmic, L., Ruple, A., London, C. A., Barber, L., Weishaar, K., … LeBlanc, A. K. (2025, February 15). Molecular Therapy, Vol. 33, pp. 1674–1686.

Optimizing canine T cell activation, expansion, and transduction

Davis, T. W., Holmes, J. C., He, A., Hess, P. R., Mariani, C. L., & Brudno, Y. (2025, April 30).

Optimizing canine T cell activation, expansion, and transduction

Davis, T. W., Holmes, J. C., He, A., Hess, P. R., Mariani, C. L., & Brudno, Y. (2025, September 11). (X. Tan, Ed.). PLoS ONE, Vol. 9.

Myeloid cell MHC I expression drives CD8+ T cell activation in nonalcoholic steatohepatitis

Adams, V. R., Collins, L. B., Williams, T. I., Holmes, J., Hess, P., Atkins, H. M., … Kennedy, A. (2024, January 11). (T. I. Williams, L. B. Collins, & A. Kennedy, Eds.). Frontiers in Immunology, Vol. 14.

A Kmer-based paired-end read de novo assembler and genotyper for canine MHC class I genotyping

Feng, Y., Hess, P. R., Tompkins, S. M., Hildebrand, W. H., & Zhao, S. (2023, January 17). IScience, Vol. 26.

Doxorubicin for treatment of histiocytic sarcoma in dogs: 31 cases (2003–2017)

Journal of the American Veterinary Medical Association, 260(14), 1827–1833.

Dog leukocyte antigen‐88*034:01 presents nonamer peptides from canine distemper virus hemagglutinin, large polymerase, and matrix proteins

Nemec, P. S., Holmes, J. C., & Hess, P. R. (2021, February 3). HLA, Vol. 2.

High-resolution characterization of the structural features and genetic variation of six feline leukocyte antigen class I loci via single molecule, real-time (SMRT) sequencing

Holmes, J. C., Scholl, E. H., Dickey, A. N., & Hess, P. R. (2021, June 26). Immunogenetics, Vol. 6.

Cancer‐testis antigens in canine histiocytic sarcoma and other malignancies

Veterinary and Comparative Oncology, 17(3), 317–328.

Incidence and risk factors associated with development of clinical cardiotoxicity in dogs receiving doxorubicin

Journal of Veterinary Internal Medicine, 33(2), 783–791.

The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif

Veterinary Immunology and Immunopathology, 197, 76–86.

The prevalent Boxer MHC class Ia allotype dog leukocyte antigen (DLA)-88*034:01 preferentially binds nonamer peptides with a defined motif

HLA, 92(6), 403–407.

Canine scent detection of canine cancer: A feasibility study

Veterinary Medicine-Research and Reports, 8, 1–7.

Canine scent detection of canine cancer: a feasibility study

Veterinary Medicine: Research and Reports, Volume 8, 69–76.

Oral melphalan for the treatment of relapsed canine lymphoma

Veterinary and Comparative Oncology, 16(1), E123–E129.

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+ T-cell specificities

Leitman, E. M., Palmer, C. D., Buus, S., Chen, F., Riddell, L., Sims, S., … Goulder, P. J. R. (2017, October 11). PLoS ONE.

Saporin-conjugated tetramers identify efficacious anti-HIV CD8+T-cell specificities

PLoS One, 12(10).

Canine acute leukaemia: 50 cases (1989-2014)

Veterinary and Comparative Oncology, 15(3), 1101–1114.

Characterization and allelic variation of the transporters associated with antigen processing (TAP) genes in the domestic dog (Canis lupus familiaris)

Developmental & Comparative Immunology, 41(4), 578–586.

Comparison of automated versus manual neutrophil counts for the detection of cellular abnormalities in dogs receiving chemotherapy: 50 cases (May to June 2008)

Cora, M. C., Neel, J. A., Grindem, C. B., Kissling, G. E., & Hess, P. R. (2013, May 17). Journal of the American Veterinary Medical Association, Vol. 242, pp. 1539–1543.

Deletion of naïve T cells recognizing the minor histocompatibility antigen HY with toxin-coupled peptide-MHC class I tetramers inhibits cognate CTL responses and alters immunodominance

Transplant Immunology, 29(1-4), 138–145.

Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

Nature, 502(7469), 105–109.

Polymorphisms and tissue expression of the feline leukocyte antigen class I loci FLAI-E, FLAI-H, and FLAI-K

Immunogenetics, 65(9), 675–689.

A cell-based MHC stabilization assay for the detection of peptide binding to the canine classical class I molecule, DLA-88

Ross, P., Holmes, J. C., Gojanovich, G. S., & Hess, P. R. (2012, September 21). Veterinary Immunology and Immunopathology, Vol. 150, pp. 206–212.

Allelic diversity at the DLA‐88 locus in Golden Retriever and Boxer breeds is limited

Ross, P., Buntzman, A. S., Vincent, B. G., Grover, E. N., Gojanovich, G. S., Collins, E. J., … Hess, P. R. (2012, May 10). Tissue Antigens, Vol. 80, pp. 175–183.

Chronic lymphocytic leukaemia in the cat: 18 cases (2000-2010)

Veterinary and Comparative Oncology, 11(4), 256–264.

Development of an ELISA to detect circulating anti-asparaginase antibodies in dogs with lymphoid neoplasia treated with Escherichia colil-asparaginase

Veterinary and Comparative Oncology, 13(2), 77–88.

Making the Most of Major Histocompatibility Complex Molecule Multimers: Applications in Type 1 Diabetes

Clinical and Developmental Immunology, 2012, 1–9.

Making the most of major histocompatibility complex molecule multimers: Applications in type 1 diabetes

[Review of ]. Clinical & Developmental Immunology.

TAK1 (MAP3K7) Signaling Regulates Hematopoietic Stem Cells through TNF-Dependent and -Independent Mechanisms

PLoS ONE, 7(11), e51073.

The Use of Peptide-Major-Histocompatibility-Complex Multimers in Type 1 Diabetes Mellitus

Gojanovich, G. S., Murray, S. L., Buntzman, A. S., Young, E. F., Vincent, B. G., & Hess, P. R. (2012, May 1). Journal of Diabetes Science and Technology.

Safety and efficacy of a xenogeneic DNA vaccine encoding for human tyrosinase as adjunctive treatment for oral malignant melanoma in dogs following surgical excision of the primary tumor

American Journal of Veterinary Research, 72(12), 1631–1638.

Evaluation of an in vitro telomeric repeat amplification protocol assay to detect telomerase activity in canine urine

American Journal of Veterinary Research, 71(12), 1468–1474.

Pathology in Practice

Palgrave, C. J., Hunter, S. A., Clarke, D. M., & Hess, P. R. (2010, October 15). Journal of the American Veterinary Medical Association, Vol. 237, pp. 911–913.

Toxin-Coupled MHC Class I Tetramers Can Specifically Ablate Autoreactive CD8+ T Cells and Delay Diabetes in Nonobese Diabetic Mice

The Journal of Immunology, 184(8), 4196–4204.

Islet lymphocyte subsets in male and female NOD mice are qualitatively similar but quantitatively distinct

Young, E. F., Hess, P. R., Arnold, L. W., Tisch, R., & Frelinger, J. A. (2009, November 1). Autoimmunity, Vol. 42, pp. 678–691.

Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein saporin

Hess, P. R., Barnes, C., Woolard, M. D., Johnson, M. D. L., Cullen, J. M., Collins, E. J., & Frelinger, J. A. (2006, December 19). Blood, Vol. 109, pp. 3300–3307.

Experimental Ehrlichia canis infection in the dog does not cause immunosuppression

Hess, P. R., English, R. V., Hegarty, B. C., Brown, G. D., & Breitschwerdt, E. B. (2005, September 17). Veterinary Immunology and Immunopathology, Vol. 109, pp. 117–125.

Thermal dose is related to duration of local control in canine sarcomas treated with thermoradiotherapy

Clinical Cancer Research, 11(14), 5206–5214.

Vaccination with mRNAs encoding tumor-associated antigens and granulocyte-macrophage colony-stimulating factor efficiently primes CTL responses, but is insufficient to overcome tolerance to a model tumor/self antigen

Hess, P. R., Boczkowski, D., Nair, S. K., Snyder, D., & Gilboa, E. (2005, August 19). Cancer Immunology Immunotherapy, Vol. 55, pp. 672–683.

Diagnostic approach to hepatobiliary disease

In Kirk's current meterinary therapy XIII, small animal practice (Vol. 13, pp. 659–664). Philadelphia: WB Saunders Co.

What is your diagnosis? Nodular lung disease

Journal of the American Veterinary Medical Association, 214(2), 193–194.

Steroid-responsive, cervical, pyogranulomatous pachymeningitis in a dog

Hess, & Sellon, R. K. (1997, September 1). Journal of the American Animal Hospital Association, Vol. 33, pp. 461–468.

Management of Portal Hypertension and Its Consequences

Hess, P. R., & Bunch, S. E. (1995, March 1). Veterinary Clinics of North America Small Animal Practice, Vol. 25, pp. 461–483.

Effect of neonatal infraorbital nerve transection on substance P- and leucine enkephalin-like immunoreactivities in trigeminal subnucleus caudalis of the rat

Rhoades, R. W., Chiaia, N. L., Hess, & Miller, M. W. (1988, July 1). Journal of Neuroscience, Vol. 8, pp. 2234–2247.

The projection from the superficial to the deep layers of the superior colliculus: an intracellular horseradish peroxidase injection study in the hamster

Mooney, R. D., Nikoletseas, M. M., Hess, Allen, Z., Lewin, A. C., & Rhoades, R. W. (1988, April 1). Journal of Neuroscience, Vol. 8, pp. 1384–1399.

Development and lesion induced reorganization of the peripheral projections of the trigeminal ganglion in rat

In L. M. Pubols & B. J. Sessle (Eds.), Effects of injury on trigeminal and spinal somatosensory systems (pp. 49–60). New York: Alan R. Liss, Inc.

Morphological characteristics of low‐threshold primary afferents in the trigeminal subnuclei interpolaris and caudalis (the medullary dorsal horn) of the golden hamster

Chiaia, N. L., Hess, P. R., Hosoi, M., & Rhoades, R. W. (1987, October 22). The Journal of Comparative Neurology, Vol. 264, pp. 527–546.

Preventing regeneration of infraorbital axons does not alter the ganglionic or transganglionic consequences of neonatal transection of this trigeminal branch

Chiaia, N. L., Hess, P. R., & Rhoades, R. W. (1987, November 1). Developmental Brain Research, Vol. 36, pp. 75–88.