When History and Heterogeneity Matter: A Tutorial on the Impact of Markov Model Specifications in the Context of Colorectal Cancer Screening
Townsley, R. M., Koutouan, P. R., Mayorga, M. E., Mills, S. D., Davis, M. M., & Hasmiller Lich, K. (2022, May 11). MEDICAL DECISION MAKING, Vol. 5.
author keywords: colorectal cancer screening; markov models; microsimulation
MeSH headings : Colonoscopy; Colorectal Neoplasms / diagnosis; Colorectal Neoplasms / epidemiology; Early Detection of Cancer / methods; Humans; Mass Screening / methods; Occult Blood
topics (OpenAlex): Colorectal Cancer Screening and Detection; Health Systems, Economic Evaluations, Quality of Life; Global Cancer Incidence and Screening
TL;DR:
Colorectal cancer screening trajectories and projected health outcomes were sensitive to the use of alternate Markov model specifications, demonstrating the importance of examining the memoryless assumption of the first-order Markovmodel when simulating health care utilization over time.
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