Works (34)

2019 journal article

Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity.

The Biochemical Journal.

Source: ORCID
Added: November 6, 2019

2017 journal article

An Internship May Not Be Enough: Enhancing Bioscience Industry Job Readiness through Practicum Experiences.

Journal of Microbiology & Biology Education, 18(1).

By: J. Cramer & P. Hamilton

Source: ORCID
Added: January 31, 2019

2016 journal article

Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish

Protein Science, 8(11), 2076–2088.

By: M. Tucker, S. MacKenzie, J. Maciag, H. Ackerman, P. Swartz, J. Yoder, P. Hamilton, A. Clark

Source: ORCID
Added: January 31, 2019

2015 article

High-Throughput and High-Content Screening Using Peptides

Carlson, R., Hyde-DeRuyscher, R., & Hamilton, P. (2015, February). Phage Display In Biotechnology and Drug Discovery, Second Edition, pp. 249–274.

By: R. Carlson, R. Hyde-DeRuyscher & P. Hamilton

Source: ORCID
Added: January 31, 2019

2015 book

High-throughput and high-content screening using peptides

In Phage Display in Biotechnology and Drug Discovery, Second Edition (pp. 249–274).

By: R. Carlson, R. Hyde-DeRuyscher & P. Hamilton

Source: ORCID
Added: February 1, 2019

2014 journal article

Characterization of a thermophilic bacteriophage of Geobacillus kaustophilus

Arch Virol, 159(10), 2771–2775.

By: T. Marks & P. Hamilton

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

Cooperative Learning through Team-Based Projects in the Biotechnology Industry †

Journal of Microbiology & Biology Education, 14(2), 221–229.

By: S. Luginbuhl & P. Hamilton

Source: ORCID
Added: January 31, 2019

2013 journal article

Improved Bone Morphogenetic Protein-2 Retention in an Injectable Collagen Matrix Using Bifunctional Peptides

PLoS ONE, 8(8), e70715.

By: P. Hamilton, M. Jansen, S. Ganesan, R. Benson, R. Hyde-DeRuyscher, W. Beyer, J. Gile, S. Nair ...

Ed(s): F. Gelain

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2012 journal article

Preparing Science-Trained Professionals for the Biotechnology Industry: A Ten-Year Perspective on a Professional Science Master’s Program

Journal of Microbiology & Biology Education, 13(1), 39–44.

By: P. Hamilton, S. Luginbuhl & M. Hyman

Source: ORCID
Added: January 31, 2019

2009 journal article

Directed Assembly of PEGylated-Peptide Coatings for Infection-Resistant Titanium Metal

J. Am. Chem. Soc., 131(31), 10992–10997.

By: X. Khoo, P. Hamilton, G. O’Toole, B. Snyder, D. Kenan & M. Grinstaff

Source: ORCID
Added: January 31, 2019

2008 conference paper

A peptide coating for the endothelialization of intravascular devices

8th World Biomaterials Congress 2008, 1, 200.

By: P. Hamilton & A. Solan

Source: ORCID
Added: February 1, 2019

2008 conference paper

Growth factor coated sutures for improved tendon repair

8th World Biomaterials Congress 2008, 1, 179.

By: P. Hamilton, B. Buehrer & D. Juzumiene

Source: ORCID
Added: February 1, 2019

2007 journal article

Endothelialization of Titanium Surfaces

Adv. Mater., 19(18), 2492–2498.

By: S. Meyers, P. Hamilton, E. Walsh, D. Kenan & M. Grinstaff

Source: ORCID
Added: January 31, 2019

2005 article

High Throughput and High Content Screening Using Peptides

Hamilton, P., Carlson, R., & Hyde-Deruyscher, R. (2005, July). Phage Display In Biotechnology and Drug Discovery, pp. 347–384.

By: P. Hamilton, R. Carlson & R. Hyde-Deruyscher

Source: ORCID
Added: January 31, 2019

2003 journal article

Identification and characterization of peptide probes directed against PKCα conformations

The Journal of Peptide Research, 61(5), 263–273.

By: S. Ashraf, E. Anderson, K. Duke, P. Hamilton & Z. Fredericks

Source: ORCID
Added: January 31, 2019

2003 journal article

Intracellular Expression of Peptide Fusions for Demonstration of Protein Essentiality in Bacteria

Antimicrobial Agents and Chemotherapy, 47(9), 2875–2881.

By: R. Benson, E. Gottlin, D. Christensen & P. Hamilton

Source: ORCID
Added: January 31, 2019

2003 article

Surrogate Ligand-Based Assay Systems for Discovery of Antibacterial Agents for Genomic Targets

Hamilton, P., & Christensen, D. (2003, May). Microbial Genomics and Drug Discovery, pp. 173–185.

By: P. Hamilton & D. Christensen

Source: ORCID
Added: January 31, 2019

2001 journal article

Identification of Enzyme Inhibitors from Phage-Displayed Combinatorial Peptide Libraries

CCHTS, 4(7), 535–543.

By: B. Kay & P. Hamilton

Source: ORCID
Added: January 31, 2019

2001 journal article

Phage display for target-based antibacterial drug discovery

Drug Discovery Today, 6(14), 721–727.

By: D. Christensen, E. Gottlin, R. Benson & P. Hamilton

Source: ORCID
Added: January 31, 2019

2000 journal article

Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries

Chemistry & Biology, 7(1), 17–25.

By: R. Hyde-DeRuyscher, L. Paige, D. Christensen, N. Hyde-DeRuyscher, A. Lim, Z. Fredericks, J. Kranz, P. Gallant ...

Source: ORCID
Added: January 31, 2019

1999 journal article

Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β

Mol. Cell. Biol., 19(12), 8226–8239.

By: C. Chang, J. Norris, H. Grøn, L. Paige, P. Hamilton, D. Kenan, D. Fowlkes, D. McDonnell

Source: ORCID
Added: January 31, 2019

1999 journal article

Estrogen receptor (ER) modulators each induce distinct conformational changes in ER   and ER  

Proceedings of the National Academy of Sciences, 96(7), 3999–4004.

By: L. Paige, D. Christensen, H. Gron, J. Norris, E. Gottlin, K. Padilla, C. Chang, L. Ballas ...

Source: ORCID
Added: January 31, 2019

1999 journal article

Peptide antagonists of the human estrogen receptor

Science, 285(5428), 744–746.

By: J. Norris, L. Paige, D. Christensen, C. Chang, M. Huacani, D. Fan, P. Hamilton, D. Fowlkes, D. McDonnell

Source: ORCID
Added: February 1, 2019

1995 article

Applying Genetic Engineering to the Structural Analysis of Proteins

Physical Methods to Characterize Pharmaceutical Proteins, pp. 329–350.

By: P. Hamilton

Source: ORCID
Added: January 31, 2019

1995 journal article

Applying genetic engineering to the structural analysis of proteins.

Pharmaceutical Biotechnology, 7, 329–350.

By: P. Hamilton

Source: ORCID
Added: February 1, 2019

1993 journal article

Expression of a single-chain antibody as a maltose binding protein fusion

Protein Engineering, Design and Selection, 6, 88.

By: P. Hamilton, M. Martinson, D. Malinowski & R. Pearson

Source: ORCID
Added: February 1, 2019

1989 journal article

A hydrogenase-linked gene in Methanobacterium thermoautotrophicum strain delta H encodes a polyferredoxin.

Proceedings of the National Academy of Sciences, 86(9), 3031–3035.

By: J. Reeve, G. Beckler, D. Cram, P. Hamilton, J. Brown, J. Krzycki, A. Kolodziej, L. Alex, W. Orme-Johnson, C. Walsh

Source: ORCID
Added: January 31, 2019

1989 journal article

Nucleotide sequence of the major outer membrane protein gene from Chlamydia trachomatis serovar H

Nucl Acids Res, 17(20), 8366–8366.

By: P. Hamilton & D. Malinowski

Source: ORCID
Added: January 31, 2019

1989 journal article

Polyferredoxin: A methanogen hydrogenase operon encodes a gene for a 12 × (4Fe4S) protein

Journal of Inorganic Biochemistry, 36(3-4), 221.

By: J. Reeve, G. Beckler, D. Cram, P. Hamilton, J. Brown, J. Krzycki, A. Kolodziej, L. Alex, W. Orme-Johnson, C. Walsh

Source: ORCID
Added: January 31, 2019

1987 article

Divergence of Methanogens, Conservation of the His I Gene Sequence in all Three Biological Kingdoms and the Status of Methanobacterium Thermoautotrophicum

Microbial Growth on C1 Compounds, pp. 255–260.

By: J. Reeve, G. Beckler, J. Brown, D. Cram, E. Haas, P. Hamilton, C. Morris, B. Sherf, C. Weil

Source: ORCID
Added: January 31, 2019

1986 journal article

Structure of methanogen genes

Systematic and Applied Microbiology, 7(1), 5–12.

By: J. Reeve, P. Hamilton, G. Beckler, C. Morris & C. Clarke

Source: ORCID
Added: January 31, 2019

1985 journal article

Sequence divergence of an archaebacterial gene cloned from a mesophilic and a thermophilic methanogen

J Mol Evol, 22(4), 351–360.

By: P. Hamilton & J. Reeve

Source: ORCID
Added: January 31, 2019

1985 journal article

Structure of genes and an insertion element in the methane producing archaebacterium Methanobrevibacter smithii

Molec. Gen. Genet., 200(1), 47–59.

By: P. Hamilton & J. Reeve

Source: ORCID
Added: January 31, 2019

1982 journal article

Beginning genetics with methanogens.

Basic Life Sciences, 19, 233–244.

By: J. Reeve, N. Trun & P. Hamilton

Source: ORCID
Added: February 1, 2019

Employment

2009 - present

North Carolina State University Raleigh, NC, US
Associate Professor Plant and Microbial Biology

Education

1980 - 1984

Ohio State University Columbus, OH, US
Ph.D in Microbiology Microbiology

1976 - 1980

University of Michigan Ann Arbor, MI, US
Bachelor of Science in Microbiology

Funding History

Funding history based on the linked ORCID record.

grant September 1, 2019 - August 1, 2022
NSF IGE: Accelerate to Industry (A2i)
National Science Foundation
grant September 15, 2015 - May 31, 2016
I-Corps: Industrial Enzymes from the Microbiomes of Household Insects
National Science Foundation - Directorate for Engineering
grant May 15, 2008 - April 30, 2009
Antibiotic-binding Peptides for Biofilm Prevention on Ventriculoperitoneal Shunts
National Institute of Neurological Disorders and Stroke
grant May 15, 2008 - April 30, 2009
Antibiotic-binding Peptides for Biofilm Prevention on Ventriculoperitoneal Shunts
National Institute of Neurological Disorders and Stroke
grant April 14, 2008 - August 1, 2009
Localized Growth Factor Therapy for Surgical Hernia Repair
National Institute of General Medical Sciences
grant April 14, 2008 - August 1, 2009
Localized Growth Factor Therapy for Surgical Hernia Repair
National Institute of General Medical Sciences
grant September 20, 2007 - August 31, 2010
Interfacial Adapters for Improved Cell Delivery to Tissues
National Heart Lung and Blood Institute
grant July 2, 2007 - June 30, 2008
Point of Care Attachment of Multiple Antibiotics onto Metal Implants
National Institute of Dental and Craniofacial Research
grant July 2, 2007 - July 31, 2011
Point of Care Attachment of Antibiotics onto Metal Implants
National Institute of Allergy and Infectious Diseases
grant July 2, 2007 - June 30, 2008
Point of Care Attachment of Multiple Antibiotics onto Metal Implants
National Institute of Dental and Craniofacial Research
grant September 30, 2006 - September 29, 2008
Discovery of a Platelet Derived Growth Factor Peptide-based Mimetic
National Institute of Diabetes and Digestive and Kidney Diseases
grant September 30, 2006 - September 29, 2008
Discovery of a Platelet Derived Growth Factor Peptide-based Mimetic
National Institute of Diabetes and Digestive and Kidney Diseases
grant September 1, 2006 - August 31, 2007
Injectable BMP-2 Formulation for Fracture Healing
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant September 1, 2006 - August 31, 2007
Injectable BMP-2 Formulation for Fracture Healing
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant June 28, 2006 - March 31, 2008
Growth Factor Coated Sutures for Improved Tendons Repair
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant June 28, 2006 - March 31, 2008
Growth Factor Coated Sutures for Improved Tendons Repair
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant July 1, 2005 - June 30, 2007
Discovery of Peptide-based Bone Morphogenic Protein Mimetics
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant July 1, 2005 - June 30, 2007
Discovery of Peptide-based Bone Morphogenic Protein Mimetics
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant April 1, 2005 - March 31, 2006
Improved Orthopedic Implant Surface Coatings
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant April 1, 2005 - March 31, 2006
Improved Orthopedic Implant Surface Coatings
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant April 1, 2004 - August 31, 2009
Improved Orthopedic Implant Surface Coatings
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant April 1, 2004 - August 31, 2009
Improved Orthopedic Implant Surface Coatings
National Institute of Arthritis and Musculoskeletal and Skin Diseases
grant September 1, 1999 - February 28, 2001
A NOVEL APPROACH TO THE DISCOVERY OF ANTIBACTERIAL DRUGS
National Institute of Allergy and Infectious Diseases
grant September 1, 1999 - February 28, 2001
A NOVEL APPROACH TO THE DISCOVERY OF ANTIBACTERIAL DRUGS
National Institute of Allergy and Infectious Diseases