@article{yao_swartz_hamilton_clark_2021, title={Remodeling hydrogen bond Interactions results in relaxed specificity of Caspase-3}, volume={41}, ISBN={1573-4935}, DOI={10.1042/BSR20203495}, journal={BIOSCIENCE REPORTS}, author={Yao, Liqi and Swartz, Paul and Hamilton, Paul T. and Clark, A. Clay}, year={2021}, month={Jan} } @article{shrestha_tung_grinshpon_swartz_hamilton_dimos_mydlarz_clark_2020, title={Caspases from scleractinian coral show unique regulatory features}, volume={295}, ISBN={1083-351X}, url={http://dx.doi.org/10.1074/jbc.ra120.014345}, DOI={10.1074/jbc.ra120.014345}, number={43}, journal={JOURNAL OF BIOLOGICAL CHEMISTRY}, publisher={Elsevier BV}, author={Shrestha, Suman and Tung, Jessica and Grinshpon, Robert D. and Swartz, Paul and Hamilton, Paul T. and Dimos, Bradford and Mydlarz, Laura and Clark, A. Clay}, year={2020}, pages={14578–14591} } @article{hamilton_2019, title={Resurrection of ancestral effector caspases identifies novel networks for evolution of substrate specificity.}, url={https://doi.org/10.1042/BCJ20190625}, DOI={10.1042/bcj20190625}, journal={The Biochemical journal}, author={Hamilton, Paul}, year={2019}, month={Nov} } @article{cramer_hamilton_2017, title={An Internship May Not Be Enough: Enhancing Bioscience Industry Job Readiness through Practicum Experiences.}, volume={18}, url={http://europepmc.org/abstract/med/28512519}, DOI={10.1128/jmbe.v18i1.1248}, number={1}, journal={Journal of microbiology & biology education}, author={Cramer, JM and Hamilton, PT}, year={2017}, month={Apr} } @article{tucker_mackenzie_maciag_dirscherl ackerman_swartz_yoder_hamilton_clay clark_2016, title={Phage display and structural studies reveal plasticity in substrate specificity of caspase-3a from zebrafish}, volume={25}, ISSN={0961-8368}, url={http://dx.doi.org/10.1002/pro.3032}, DOI={10.1002/pro.3032}, number={11}, journal={Protein Science}, publisher={Wiley}, author={Tucker, Matthew B. and MacKenzie, Sarah H. and Maciag, Joseph J. and Dirscherl Ackerman, Hayley and Swartz, Paul and Yoder, Jeffrey A. and Hamilton, Paul T. and Clay Clark, A.}, year={2016}, month={Sep}, pages={2076–2088} } @article{carlson_hyde-deruyscher_hamilton_2015, title={High-Throughput and High-Content Screening Using Peptides}, DOI={10.1201/b18196-11}, journal={Phage Display In Biotechnology and Drug Discovery, Second Edition}, publisher={Informa UK Limited}, author={Carlson, Robert and Hyde-DeRuyscher, Robin and Hamilton, Paul}, year={2015}, month={Feb}, pages={249–274} } @book{carlson_hyde-deruyscher_hamilton_2015, title={High-throughput and high-content screening using peptides}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85053971671&partnerID=MN8TOARS}, DOI={10.1201/b18196}, journal={Phage Display in Biotechnology and Drug Discovery, Second Edition}, author={Carlson, R.O. and Hyde-DeRuyscher, R. and Hamilton, P.T.}, year={2015}, pages={249–274} } @article{marks_hamilton_2014, title={Characterization of a thermophilic bacteriophage of Geobacillus kaustophilus}, volume={159}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84907692380&partnerID=MN8TOARS}, DOI={10.1007/s00705-014-2101-8}, number={10}, journal={Arch Virol}, publisher={Springer Science \mathplus Business Media}, author={Marks, Timothy J. and Hamilton, Paul T.}, year={2014}, month={May}, pages={2771–2775} } @article{luginbuhl_hamilton_2013, title={Cooperative Learning through Team-Based Projects in the Biotechnology Industry †}, volume={14}, DOI={10.1128/jmbe.v14i2.608}, number={2}, journal={Journal of Microbiology & Biology Education}, publisher={American Society for Microbiology}, author={Luginbuhl, Sarah C. and Hamilton, Paul T.}, year={2013}, pages={221–229} } @article{hamilton_jansen_ganesan_benson_hyde-deruyscher_beyer_gile_nair_hodges_grøn_et al._2013, title={Improved Bone Morphogenetic Protein-2 Retention in an Injectable Collagen Matrix Using Bifunctional Peptides}, volume={8}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84881342868&partnerID=MN8TOARS}, DOI={10.1371/journal.pone.0070715}, number={8}, journal={PLoS ONE}, publisher={Public Library of Science (PLoS)}, author={Hamilton, Paul T. and Jansen, Michelle S. and Ganesan, Sathya and Benson, R. Edward and Hyde-DeRuyscher, Robin and Beyer, Wayne F. and Gile, Joseph C. and Nair, Shrikumar A. and Hodges, Jonathan A. and Grøn, Hanne and et al.}, editor={Gelain, FabrizioEditor}, year={2013}, month={Aug}, pages={e70715} } @article{hamilton_luginbuhl_hyman_2012, title={Preparing Science-Trained Professionals for the Biotechnology Industry: A Ten-Year Perspective on a Professional Science Master’s Program}, volume={13}, ISSN={1935-7877}, url={https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577309/}, DOI={10.1128/jmbe.v13i1.375}, abstractNote={The biotechnology industry has a need for business-savvy scientists; however, this is not the way scientists are traditionally trained at universities and colleges. To address this need, universities have developed Professional Science Master’s (PSM) degree programs that offer advanced training in a technical field along with professional skills development through team-based projects and internships. Nearly ten years ago, the Department of Microbiology at NCSU started a PSM program in Microbial Biotechnology (MMB). This article provides an overview of the MMB program, and shares some of the lessons that we have learned.}, number={1}, journal={Journal of Microbiology & Biology Education : JMBE}, publisher={American Society for Microbiology}, author={Hamilton, Paul T. and Luginbuhl, Sarah C. and Hyman, Michael}, year={2012}, month={May}, pages={39–44} } @article{khoo_hamilton_o’toole_snyder_kenan_grinstaff_2009, title={Directed Assembly of PEGylated-Peptide Coatings for Infection-Resistant Titanium Metal}, volume={131}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-68249136655&partnerID=MN8TOARS}, DOI={10.1021/ja9020827}, number={31}, journal={J. Am. Chem. Soc.}, publisher={American Chemical Society (ACS)}, author={Khoo, Xiaojuan and Hamilton, Paul and O’Toole, George A. and Snyder, Brian D. and Kenan, Daniel J. and Grinstaff, Mark W.}, year={2009}, month={Aug}, pages={10992–10997} } @inproceedings{hamilton_solan_2008, title={A peptide coating for the endothelialization of intravascular devices}, volume={1}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84869012621&partnerID=MN8TOARS}, booktitle={8th World Biomaterials Congress 2008}, author={Hamilton, P.T. and Solan, A.}, year={2008}, pages={200} } @inproceedings{hamilton_buehrer_juzumiene_2008, title={Growth factor coated sutures for improved tendon repair}, volume={1}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84869010182&partnerID=MN8TOARS}, booktitle={8th World Biomaterials Congress 2008}, author={Hamilton, P.T. and Buehrer, B. and Juzumiene, D.}, year={2008}, pages={179} } @article{meyers_hamilton_walsh_kenan_grinstaff_2007, title={Endothelialization of Titanium Surfaces}, volume={19}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-34748856343&partnerID=MN8TOARS}, DOI={10.1002/adma.200700029}, number={18}, journal={Adv. Mater.}, publisher={Wiley-Blackwell}, author={Meyers, S. R. and Hamilton, P. T. and Walsh, E. B. and Kenan, D. J. and Grinstaff, M. W.}, year={2007}, month={Sep}, pages={2492–2498} } @article{hamilton_carlson_hyde-deruyscher_2005, title={High Throughput and High Content Screening Using Peptides}, DOI={10.1201/9780849359125.ch9}, journal={Phage Display In Biotechnology and Drug Discovery}, publisher={Informa UK Limited}, author={Hamilton, Paul and Carlson, Robert and Hyde-Deruyscher, Robin}, year={2005}, month={Jul}, pages={347–384} } @article{ashraf_anderson_duke_hamilton_fredericks_2003, title={Identification and characterization of peptide probes directed against PKCα conformations}, volume={61}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0038025879&partnerID=MN8TOARS}, DOI={10.1034/j.1399-3011.2003.00056.x}, number={5}, journal={The Journal of Peptide Research}, publisher={Wiley-Blackwell}, author={Ashraf, S. S. and Anderson, E. and Duke, K. and Hamilton, P.T. and Fredericks, Z.}, year={2003}, month={Mar}, pages={263–273} } @article{benson_gottlin_christensen_hamilton_2003, title={Intracellular Expression of Peptide Fusions for Demonstration of Protein Essentiality in Bacteria}, volume={47}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0041922662&partnerID=MN8TOARS}, DOI={10.1128/aac.47.9.2875-2881.2003}, number={9}, journal={Antimicrobial Agents and Chemotherapy}, publisher={American Society for Microbiology}, author={Benson, R. E. and Gottlin, E. B. and Christensen, D. J. and Hamilton, P. T.}, year={2003}, month={Aug}, pages={2875–2881} } @article{hamilton_christensen_2003, title={Surrogate Ligand-Based Assay Systems for Discovery of Antibacterial Agents for Genomic Targets}, DOI={10.1201/9780203911464.ch11}, journal={Microbial Genomics and Drug Discovery}, publisher={Informa UK Limited}, author={Hamilton, Paul and Christensen, Dale}, year={2003}, month={May}, pages={173–185} } @article{kay_hamilton_2001, title={Identification of Enzyme Inhibitors from Phage-Displayed Combinatorial Peptide Libraries}, volume={4}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0034786701&partnerID=MN8TOARS}, DOI={10.2174/1386207013330760}, number={7}, journal={CCHTS}, publisher={Bentham Science Publishers Ltd.}, author={Kay, Brian and Hamilton, Paul}, year={2001}, month={Nov}, pages={535–543} } @article{christensen_gottlin_benson_hamilton_2001, title={Phage display for target-based antibacterial drug discovery}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0035395224&partnerID=MN8TOARS}, DOI={10.1016/s1359-6446(01)01853-0}, number={14}, journal={Drug Discovery Today}, publisher={Elsevier BV}, author={Christensen, Dale J and Gottlin, Elizabeth B and Benson, R.Edward and Hamilton, Paul T}, year={2001}, month={Jul}, pages={721–727} } @article{hyde-deruyscher_paige_christensen_hyde-deruyscher_lim_fredericks_kranz_gallant_zhang_rocklage_et al._2000, title={Detection of small-molecule enzyme inhibitors with peptides isolated from phage-displayed combinatorial peptide libraries}, volume={7}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0034092470&partnerID=MN8TOARS}, DOI={10.1016/s1074-5521(00)00062-4}, number={1}, journal={Chemistry & Biology}, publisher={Elsevier BV}, author={Hyde-DeRuyscher, R and Paige, LA and Christensen, DJ and Hyde-DeRuyscher, N and Lim, A and Fredericks, ZL and Kranz, J and Gallant, P and Zhang, J and Rocklage, SM and et al.}, year={2000}, month={Jan}, pages={17–25} } @article{chang_norris_grøn_paige_hamilton_kenan_fowlkes_mcdonnell_1999, title={Dissection of the LXXLL Nuclear Receptor-Coactivator Interaction Motif Using Combinatorial Peptide Libraries: Discovery of Peptide Antagonists of Estrogen Receptors α and β}, volume={19}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0033513582&partnerID=MN8TOARS}, DOI={10.1128/mcb.19.12.8226}, number={12}, journal={Mol. Cell. Biol.}, publisher={American Society for Microbiology}, author={Chang, Ching-yi and Norris, John D. and Grøn, Hanne and Paige, Lisa A. and Hamilton, Paul T. and Kenan, Daniel J. and Fowlkes, Dana and McDonnell, Donald P.}, year={1999}, pages={8226–8239} } @article{paige_christensen_gron_norris_gottlin_padilla_chang_ballas_hamilton_mcdonnell_et al._1999, title={Estrogen receptor (ER) modulators each induce distinct conformational changes in ER   and ER  }, volume={96}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-2642544810&partnerID=MN8TOARS}, DOI={10.1073/pnas.96.7.3999}, number={7}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Paige, L. A. and Christensen, D. J. and Gron, H. and Norris, J. D. and Gottlin, E. B. and Padilla, K. M. and Chang, C.-y. and Ballas, L. M. and Hamilton, P. T. and McDonnell, D. P. and et al.}, year={1999}, month={Mar}, pages={3999–4004} } @article{norris_paige_christensen_chang_huacani_fan_hamilton_fowlkes_mcdonnell_1999, title={Peptide antagonists of the human estrogen receptor}, volume={285}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0033618510&partnerID=MN8TOARS}, DOI={10.1126/science.285.5428.744}, number={5428}, journal={Science}, author={Norris, J.D. and Paige, L.A. and Christensen, D.J. and Chang, C.-Y. and Huacani, M.R. and Fan, D. and Hamilton, P.T. and Fowlkes, D.M. and McDonnell, D.P.}, year={1999}, pages={744–746} } @article{hamilton_1995, title={Applying Genetic Engineering to the Structural Analysis of Proteins}, DOI={10.1007/978-1-4899-1079-0_9}, journal={Physical Methods to Characterize Pharmaceutical Proteins}, publisher={Springer Science \mathplus Business Media}, author={Hamilton, Paul T.}, year={1995}, pages={329–350} } @article{hamilton_1995, title={Applying genetic engineering to the structural analysis of proteins.}, volume={7}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0029449448&partnerID=MN8TOARS}, journal={Pharmaceutical biotechnology}, author={Hamilton, P.T.}, year={1995}, pages={329–350} } @article{hamilton_martinson_malinowski_pearson_1993, title={Expression of a single-chain antibody as a maltose binding protein fusion}, volume={6}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84962999165&partnerID=MN8TOARS}, DOI={10.1093/protein/6.Supplement.88-b}, journal={Protein Engineering, Design and Selection}, author={Hamilton, P. and Martinson, M. and Malinowski, D. and Pearson, R.}, year={1993}, pages={88} } @article{reeve_beckler_cram_hamilton_brown_krzycki_kolodziej_alex_orme-johnson_walsh_1989, title={A hydrogenase-linked gene in Methanobacterium thermoautotrophicum strain delta H encodes a polyferredoxin.}, volume={86}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0024670961&partnerID=MN8TOARS}, DOI={10.1073/pnas.86.9.3031}, number={9}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Reeve, J. N. and Beckler, G. S. and Cram, D. S. and Hamilton, P. T. and Brown, J. W. and Krzycki, J. A. and Kolodziej, A. F. and Alex, L. and Orme-Johnson, W. H. and Walsh, C. T.}, year={1989}, month={May}, pages={3031–3035} } @article{hamilton_malinowski_1989, title={Nucleotide sequence of the major outer membrane protein gene from Chlamydia trachomatis serovar H}, volume={17}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0024978653&partnerID=MN8TOARS}, DOI={10.1093/nar/17.20.8366}, number={20}, journal={Nucl Acids Res}, publisher={Oxford University Press (OUP)}, author={Hamilton, Paul T. and Malinowski, Douglas P.}, year={1989}, pages={8366–8366} } @article{reeve_beckler_cram_hamilton_brown_krzycki_kolodziej_alex_orme-johnson_walsh_1989, title={Polyferredoxin: A methanogen hydrogenase operon encodes a gene for a 12 × (4Fe4S) protein}, volume={36}, DOI={10.1016/0162-0134(89)84221-7}, number={3-4}, journal={Journal of Inorganic Biochemistry}, publisher={Elsevier BV}, author={Reeve, J. and Beckler, G. and Cram, D. and Hamilton, P. and Brown, J. and Krzycki, J. and Kolodziej, A. and Alex, L. and Orme-Johnson, W.H. and Walsh, C.T.}, year={1989}, month={Aug}, pages={221} } @article{reeve_beckler_brown_cram_haas_hamilton_morris_sherf_weil_1987, title={Divergence of Methanogens, Conservation of the His I Gene Sequence in all Three Biological Kingdoms and the Status of Methanobacterium Thermoautotrophicum}, DOI={10.1007/978-94-009-3539-6_31}, journal={Microbial Growth on C1 Compounds}, publisher={Springer Science \mathplus Business Media}, author={Reeve, John N. and Beckler, Gregory S. and Brown, James W. and Cram, David S. and Haas, Elizabeth S. and Hamilton, Paul T. and Morris, Christina J. and Sherf, Bruce A. and Weil, Clifford F.}, year={1987}, pages={255–260} } @article{reeve_hamilton_beckler_morris_clarke_1986, title={Structure of methanogen genes}, volume={7}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0022467785&partnerID=MN8TOARS}, DOI={10.1016/s0723-2020(86)80116-3}, number={1}, journal={Systematic and Applied Microbiology}, publisher={Elsevier BV}, author={Reeve, John N. and Hamilton, Paul T. and Beckler, Gregory S. and Morris, Christina J. and Clarke, Colin H.}, year={1986}, month={Mar}, pages={5–12} } @article{hamilton_reeve_1985, title={Sequence divergence of an archaebacterial gene cloned from a mesophilic and a thermophilic methanogen}, volume={22}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0022321706&partnerID=MN8TOARS}, DOI={10.1007/bf02115691}, number={4}, journal={J Mol Evol}, publisher={Springer Science \mathplus Business Media}, author={Hamilton, Paul T. and Reeve, John N.}, year={1985}, pages={351–360} } @article{hamilton_reeve_1985, title={Structure of genes and an insertion element in the methane producing archaebacterium Methanobrevibacter smithii}, volume={200}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0021871395&partnerID=MN8TOARS}, DOI={10.1007/bf00383311}, number={1}, journal={Molec. Gen. Genet.}, publisher={Springer Science \mathplus Business Media}, author={Hamilton, Paul T. and Reeve, John N.}, year={1985}, pages={47–59} } @article{reeve_trun_hamilton_1982, title={Beginning genetics with methanogens.}, volume={19}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-0020009847&partnerID=MN8TOARS}, journal={Basic life sciences}, author={Reeve, J.N. and Trun, N.J. and Hamilton, P.T.}, year={1982}, pages={233–244} }