Parsa Zareiesfandabadi

Works (2)

Updated: June 17th, 2023 21:54

2021 article

Automated tracking of S. pombe spindle elongation dynamics

Uzsoy, A. S. M., Zareiesfandabadi, P., Jennings, J., Kemper, A. F., & Elting, M. W. (2021, July 8). JOURNAL OF MICROSCOPY, Vol. 6.

By: A. Uzsoy  n, P. Zareiesfandabadi n, J. Jennings n, A. Kemper  n & M. Elting n 

author keywords: automation; cell division; fission yeast; fluorescence imaging; image analysis; live-cell imaging; mitotic spindle
MeSH headings : Microscopy; Microtubules / chemistry; Mitosis; Schizosaccharomyces; Spindle Apparatus
TL;DR: An ImageJ plugin is developed that can automatically track S. pombe spindle length over time and replace manual or semi-automated tracking of spindle elongation dynamics, which will allow automatic analysis of large microscopy data sets and facilitate screening for effects of cell biological perturbations on mitotic progression. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 7, 2021

2021 journal article

p Force by minus-end motors Dhc1 and Klp2 collapses the S. pombe spindle after laser ablation

BIOPHYSICAL JOURNAL, 121(2), 263–276.

By: P. Zareiesfandabadi n & M. Elting n 

Contributors: M. Elting n 

MeSH headings : Dyneins / metabolism; Kinesins / genetics; Laser Therapy; Microtubule-Associated Proteins / metabolism; Microtubules / metabolism; Mitosis; Schizosaccharomyces / genetics; Schizosaccharomyces pombe Proteins / metabolism; Spindle Apparatus / metabolism
TL;DR: This work finds that previously hypothesized viscoelastic relaxation of the nucleus cannot explain spindle shortening in response to laser ablation and finds that spindle pole bodies collapse toward each other after ablation, but spindle geometry is often rescued, allowing spindles to resume elongation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 7, 2022

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