Qingyang Liu

Works (2)

Updated: July 5th, 2023 15:43

2015 article

Conditional Control of Alternative Splicing through Light-Triggered Splice-Switching Oligonucleotides

Hemphill, J., Liu, Q., Uprety, R., Samanta, S., Tsang, M., Juliano, R. L., & Deiters, A. (2015, March 3). Journal of the American Chemical Society.

By: J. Hemphill n, Q. Liu n, R. Uprety n, S. Samanta *, M. Tsang *, R. Juliano*, A. Deiters n

MeSH headings : Alternative Splicing / radiation effects; Animals; HeLa Cells; Humans; Light; Oligonucleotides / chemistry; Oligonucleotides / genetics; Zebrafish
topics (OpenAlex): Photochromic and Fluorescence Chemistry; RNA Interference and Gene Delivery; DNA and Nucleic Acid Chemistry
TL;DR: This work addressed site-specific installation of light-removable nucleobase-caging groups as well as photocleavable backbone linkers into synthetic SSOs that enables optochemical OFF → ON and ON → OFF switching of their activity and thus precise control of alternative splicing. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2013 article

Optochemical Control of Deoxyoligonucleotide Function via a Nucleobase-Caging Approach

Liu, Q., & Deiters, A. (2013, August 28). Accounts of Chemical Research.

By: Q. Liu n & A. Deiters n

MeSH headings : Base Sequence; DNA, Catalytic / genetics; DNA, Catalytic / metabolism; Humans; Light; Oligonucleotides / chemistry; Oligonucleotides / metabolism; Photochemical Processes; Proteins / metabolism; RNA / chemistry; RNA / metabolism
topics (OpenAlex): Photochromic and Fluorescence Chemistry; Advanced biosensing and bioanalysis techniques; DNA and Nucleic Acid Chemistry
TL;DR: The application of caged nucleobases to the photoregulation of DNA function is focused on and light-activated DNA logic operations are developed, an advance that may lay the foundation for the optochemical control of complex DNA calculations. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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