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Works (8)
Updated: October 16th, 2024 05:03
2024 journal article
Integrated Time Nanosecond Pulse Irreversible Electroporation (INSPIRE): Assessment of Dose, Temperature, and Voltage on Experimental and Clinical Treatment Outcomes
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 71(5), 1511–1520.
author keywords: Temperature measurement; Tumors; Electroporation; Electric fields; Delays; Temperature sensors; Three-dimensional displays; Electro-thermal therapy; non-thermal high frequency irreversible electroporation; pulsed field ablation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 17, 2024
2024 journal article
Investigation of integrated time nanosecond pulse irreversible electroporation against spontaneous equine melanoma
FRONTIERS IN VETERINARY SCIENCE, 11.
author keywords: focal ablation; pulsed field ablation; INSPIRE; skin cancer; clinical trial
TL;DR:
This novel therapeutic approach has the potential to expand the role of pulsed electric fields in veterinary patients, especially when general anesthesia is contraindicated, and warrants future studies to demonstrate the efficacy of INSPIRE as a solid tumor treatment.
(via Semantic Scholar)
open access via www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 19, 2024
2024 journal article
Treatment of Spontaneous Tumors With Algorithmically Controlled Electroporation
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 71(10), 2814–2822.
author keywords: Electrodes; Temperature sensors; Tumors; Needles; Melanoma; Electroporation; Finite element analysis; Pulsed field ablation; melanoma treatment; non-thermal irreversible electroporation; temperature feedback; cancer therapy
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 22, 2024
2022 journal article
Polymer Nanoparticles Enhance Irreversible Electroporation In Vitro
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 69(7), 2353–2362.
author keywords: Nanoparticles; Electric fields; Electroporation; Media; Polymers; Electrodes; Tumors; Irreversible electroporation; pulsed electric fields; tumor ablation; oncology; nanoparticle; nanobiotechnology; flash nanoprecipitation; polyelectrolyte
MeSH headings : Ablation Techniques; Electric Conductivity; Electroporation / methods; Nanoparticles; Polymers
TL;DR:
Results demonstrate the synergy of a combined cationic polymer nanoparticle and pulsed electric field treatment for the ablation of cancer cells, and set the foundation for polymer nanoparticles engineered specifically for irreversible electroporation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 11, 2022
2020 journal article
Algorithmically Controlled Electroporation: A Technique for Closed Loop Temperature Regulated Pulsed Electric Field Cancer Ablation
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 67(8), 2176–2186.
author keywords: Temperature control; Temperature measurement; Temperature sensors; Electric fields; Protocols; Temperature dependence; In vitro; Non-thermal high frequency irreversible electroporation; electro-thermal therapy; pulsed electric field; bioelectric; electroporation
MeSH headings : Electricity; Electroporation; Humans; Models, Theoretical; Neoplasms; Temperature
TL;DR:
The results of this study indicate ablative outcomes due to exposure to pulses on the order of one microsecond may be thermally mediated and dependent on local tissue temperatures.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 10, 2020
2020 journal article
Electro-Thermal Therapy Algorithms and Active Internal Electrode Cooling Reduce Thermal Injury in High Frequency Pulsed Electric Field Cancer Therapies
ANNALS OF BIOMEDICAL ENGINEERING, 49(1), 191–202.
author keywords: Electro-thermal therapy; Focal ablation; Non-thermal irreversible electroporation; H-FIRE; Liver cancer
MeSH headings : Ablation Techniques / adverse effects; Algorithms; Electrodes; Electroporation; Liver / surgery; Neoplasms / therapy; Temperature
TL;DR:
It was demonstrated that the addition of internal electrode cooling and active temperature control algorithms reduced ETT treatment times by 84% (from 343 to 54 s) vs. non-cooled temperature control strategies with equivalent thermal injury volumes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 15, 2020
2020 journal article
Electro-thermal therapy: Microsecond duration pulsed electric field tissue ablation with dynamic temperature control algorithms
COMPUTERS IN BIOLOGY AND MEDICINE, 121.
author keywords: Cancer therapy; Irreversible electroporation; Thermal ablation; H-FIRE; NK-IRE
MeSH headings : Algorithms; Electrodes; Electroporation; Liver / surgery; Temperature
TL;DR:
The results establish ETT as a viable method for hepatic tumor treatment with ablation profiles equivalent to other energy based techniques and the single applicator and multi-applicator approaches demonstrated may enable the treatment of complex tumor geometries.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 13, 2020
2020 journal article
Temperature Dependence of High Frequency Irreversible Electroporation Evaluated in a 3D Tumor Model
ANNALS OF BIOMEDICAL ENGINEERING, 48(8), 2233–2246.
author keywords: Nano-knife irreversible electroporation (NK-IRE); Electro thermal therapy; Tissue ablation; Cancer therapy; Integrated energized time (IET); Pulsed electric fields
MeSH headings : Cell Death; Cell Line, Tumor; Cell Survival; Electroporation; Glioblastoma / metabolism; Glioblastoma / pathology; Humans; Models, Biological; Temperature
TL;DR:
Results were found for pancreatic cancer cells which indicate that tissue temperature may be a significant factor affecting H-FIRE ablation size and treatment planning in vivo while lower temperatures may be useful in maintaining cell viability for transfection applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020
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