Rodolphe Barrangou

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Foley, M. H., Walker, M. E., Stewart, A. K., O'Flaherty, S., Gentry, E. C., Patel, S., … Theriot, C. M. (2023, March 13). NATURE MICROBIOLOGY, Vol. 3.

Impact of Pomegranate on Probiotic Growth, Viability, Transcriptome and Metabolism

MICROORGANISMS, 11(2).

Next-Generation Gene Editing - Current Opinion in Biomedical Engineering Mining Microbial Organisms to Discover and Characterize Novel CRISPR-Cas Systems

Current Opinion in Biomedical Engineering.

Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing

Adler, B. A., Hessler, T., Cress, B. F., Lahiri, A., Mutalik, V. K., Barrangou, R., … Doudna, J. A. (2022, October 31). NATURE MICROBIOLOGY, Vol. 10.

CRISPR-based engineering of phages for in situ bacterial base editing

Proceedings of the National Academy of Sciences.

Clustered Regularly Interspaced Short Palindromic Repeats Genotyping of Multidrug-Resistant Salmonella Heidelberg Strains Isolated From the Poultry Production Chain Across Brazil

FRONTIERS IN MICROBIOLOGY, 13.

Functional characterization of diverse type I-F CRISPR-associated transposons

Roberts, A., Nethery, M. A., & Barrangou, R. (2022, November 17). NUCLEIC ACIDS RESEARCH, Vol. 11.

Genomic and epigenetic landscapes drive CRISPR-based genome editing in Bifidobacterium

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(30).

Metabolomic Analysis of Lactobacillus acidophilus, L. gasseri, L. crispatus, and Lacticaseibacillus rhamnosus Strains in the Presence of Pomegranate Extract

FRONTIERS IN MICROBIOLOGY, 13.

Next-Generation Foods and CRISPR Engineering

Barrangou, R. (2022, August 11).

RNA-targeting CRISPR-Cas13 Provides Broad-spectrum Phage Immunity

Adler, B. A., Hessler, T., Cress, B. F., Mutalik, V. K., Barrangou, R., Banfield, J., & Doudna, J. A. (2022, March 26). (Vol. 3). Vol. 3.

Turning CRISPR on with antibiotics

Barrangou, R., & Marraffini, L. A. (2022, January 12). CELL HOST & MICROBE, Vol. 30, pp. 12–14.

(Broken) Promises of Sustainable Food and Agriculture through New Biotechnologies: The CRISPR Case

CRISPR JOURNAL, 4(1), 25–31.

Building a Resilient, Sustainable, and Healthier Food Supply Through Innovation and Technology

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021, Vol. 12, pp. 1–28.

CRISPRclassify: Repeat-Based Classification of CRISPR Loci

CRISPR JOURNAL, 4(4), 558–574.

Comparative Genomic Analyses and CRISPR-Cas Characterization of Cutibacterium acnes Provide Insights Into Genetic Diversity and Typing Applications

FRONTIERS IN MICROBIOLOGY, 12.

In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression

MBIO, 12(1).

Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(6).

Portable CRISPR-Cas9(N) System for Flexible Genome Engineering in Lactobacillus acidophilus, Lactobacillus gasseri, and Lactobacillus paracasei

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 87(6).

Species- and site-specific genome editing in complex bacterial communities

Rubin, B. E., Diamond, S., Cress, B. F., Crits-Christoph, A., Lou, Y. C., Borges, A. L., … Doudna, J. A. (2021, December 6). NATURE MICROBIOLOGY, Vol. 12.

Todd R. Klaenhammer, an inspirational food microbiologist who leaves a lasting legacy

Barrangou, R., & Hill, C. (2021, June 1). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 118.

Toward inclusive global governance of human genome editing

Yu, H., Xue, L., Barrangou, R., Chen, S., & Huang, Y. (2021, November 23). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 118.

Whole-genome sequencing analysis and CRISPR genotyping of rare antibiotic-resistant Salmonella enterica serovars isolated from food and related sources

FOOD MICROBIOLOGY, 93.

Adaptive response to iterative passages of five Lactobacillus species in simulated vaginal fluid

BMC Microbiology, 20(1).

Applications of CRISPR-Cas systems in lactic acid bacteria

FEMS Microbiology Reviews, 44(5), 523–537.

CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures

Barrangou, R., & Sontheimer, E. J. (2020, March 5). MOLECULAR CELL, Vol. 77, pp. 934–936.

Characterization and applications of Type I CRISPR-Cas systems

Biochemical Society Transactions, 48(1), 15–23.

Combining omics technologies with CRISPR-based genome editing to study food microbes

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 61, 198–208.

Comparative Analysis of Lactobacillus gasseri and Lactobacillus crispatus Isolated From Human Urogenital and Gastrointestinal Tracts

FRONTIERS IN MICROBIOLOGY, 10.

Complete Genome Sequence of Lactobacillus johnsonii NCK2677, Isolated from Mice

Microbiology Resource Announcements, 9(43).

Comprehensive Mining and Characterization of CRISPR-Cas Systems in Bifidobacterium

Microorganisms, 8(5), 720.

Deletion of S-Layer Associated Ig-Like Domain Protein Disrupts the Lactobacillus acidophilus Cell Surface

FRONTIERS IN MICROBIOLOGY, 11.

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants

[Review of ]. NATURE REVIEWS MICROBIOLOGY, 18(2), 67–83.

Genomic characterization of Lactobacillus fermentum DSM 20052

BMC Genomics, 21(1).

Host and body site-specific adaptation of Lactobacillus crispatus genomes

NAR Genomics and Bioinformatics, 2(1).

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

MBio, 11(2).

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

CRISPR JOURNAL, 3(5), 332–349.

S-layer associated proteins contribute to the adhesive and immunomodulatory properties of Lactobacillus acidophilus NCFM

BMC Microbiology, 20(1).

Sharing the CRISPR Toolbox with an Expanding Community

CRISPR JOURNAL, 3(4), 248–252.

Shutting down RNA-targeting CRISPR

Barrangou, R., & Sontheimer, E. J. (2020, July 3). SCIENCE, Vol. 369, pp. 31–32.

Strain-Dependent Inhibition of Clostridioides difficile by Commensal Clostridia Carrying the Bile Acid-Inducible ( bai ) Operon

Journal of Bacteriology, 202(11).

Strain-dependent inhibition of Clostridioides difficile by commensal Clostridia encoding the bile acid inducible (bai) operon

Reed, A. D., Nethery, M. A., Stewart, A., Barrangou, R., & Theriot, C. M. (2020, January 23). (Vol. 1). Vol. 1.

Applications of CRISPR Technologies Across the Food Supply Chain

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10, Vol. 10, pp. 133–150.

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

PLOS PATHOGENS, 15(3).

Bringing CRISPR to the Cinema

The CRISPR Journal, 2(4), 187–187.

CRISPR Visualizer: rapid identification and visualization of CRISPR loci via an automated high-throughput processing pipeline

RNA BIOLOGY, 16(4), 577–584.

CRISPR on the Move in 2019

The CRISPR Journal, 2(1), 1–2.

CRISPR-Directed Microbiome Manipulation across the Food Supply Chain

[Review of ]. TRENDS IN MICROBIOLOGY, 27(6), 489–496.

Characterization and Repurposing of Type I and Type II CRISPR-Cas Systems in Bacteria

[Review of ]. JOURNAL OF MOLECULAR BIOLOGY, 431(1), 21–33.

Collaborative networks in gene editing

Huang, Y., Porter, A., Zhang, Y., & Barrangou, R. (2019, October). NATURE BIOTECHNOLOGY, Vol. 37, pp. 1107–1109.

Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems

RNA BIOLOGY, 16(4), 435–448.

Comparative genomics of eight Lactobacillus buchneri strains isolated from food spoilage

BMC GENOMICS, 20(1).

Foresight is 2020: Ten Bold Predictions for the New CRISPR Year

The CRISPR Journal, 2(6), 341–342.

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

Proceedings of the National Academy of Sciences.

Harnessing CRISPR-Cas systems for precision engineering of designer probiotic lactobacilli

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 56, 163–171.

Outcomes and characterization of chromosomal self-targeting by native CRISPR-Cas systems in Streptococcus thermophilus

FEMS MICROBIOLOGY LETTERS, 366(9).

Partnering with bioRxiv

The CRISPR Journal, 2(6), 342–342.

Predicting and visualizing features of CRISPR-Cas systems

CRISPR-CAS ENZYMES, Vol. 616, pp. 1–25.

Profile of Rodolphe Barrangou

Proceedings of the National Academy of Sciences, 116(32), 15754–15756.

Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci

NATURE MICROBIOLOGY, 4(6), 956–963.

Short communication: Transcriptional response to a large genomic island deletion in the dairy starter culture Streptococcus thermophilus

JOURNAL OF DAIRY SCIENCE, 102(9), 7800–7806.

Taking CRISPR to New Heights

The CRISPR Journal, 2(3), 133–133.

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells

NATURE BIOTECHNOLOGY, 37(12), 1493-+.

The repurposing of type I-E CRISPR-Cascade for gene activation in plants

Communications Biology.

Thinking About CRISPR: The Ethics of Human Genome Editing

The CRISPR Journal, 2(5), 247–248.

Time To Let CRISPR B.E.?

The CRISPR Journal, 2(2), 67–67.

Advances in Industrial Biotechnology Using CRISPR-Cas Systems

[Review of ]. TRENDS IN BIOTECHNOLOGY, 36(2), 134–146.

CRISPR Craziness: A Response to the EU Court Ruling

The CRISPR Journal, 1(4), 251–252.

CRISPR Crossroads for Genome Editing

The CRISPR Journal, 1(6), 349–350.

CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems

CRISPR JOURNAL, 1(2), 171–181.

Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli

Scientific Reports, 8(1).

Conserved Genome Organization and Core Transcriptome of the Lactobacillus acidophilus Complex

FRONTIERS IN MICROBIOLOGY, 9.

Cultivating CRISPR

The CRISPR Journal, 1(2), 99–100.

Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri

MICROBIOLOGY-SGM, 164(9), 1098–1111.

Enabling the Rise of a CRISPR World

The CRISPR Journal, 1(3), 205–208.

Engineering Components of the Lactobacillus S-Layer for Biotherapeutic Applications

[Review of ]. FRONTIERS IN MICROBIOLOGY, 9.

Expanding the CRISPR Landscape on a cas by cas Basis

The CRISPR Journal, 1(5), 303–303.

Immune loss as a driver of coexistence during host-phage coevolution

ISME JOURNAL, 12(2), 585–597.

Insights into the Human Virome Using CRISPR Spacers from Microbiomes

[Review of ]. VIRUSES-BASEL, 10(9).

Keep Calm and CRISPR On

Barrangou, R. (2018, February). CRISPR JOURNAL, Vol. 1, pp. 1–3.

Lactobacillus gasseri CRISPR-Cas9 characterization In Vitro reveals a flexible mode of protospacer-adjacent motif recognition

PLOS ONE, 13(2).

MasterChef at Work: An Interview with Rodolphe Barrangou

The CRISPR Journal, 1(3), 219–222.

Mining for novel bacterial defence systems

Barrangou, R., & Oost, J. (2018, May). NATURE MICROBIOLOGY, Vol. 3, pp. 535–536.

Phenotypic and genotypic diversity of Lactobacillus buchneri strains isolated from spoiled, fermented cucumber

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 280, 46–56.

Pomp and Circumstance: Making the Case for CRISPR

The CRISPR Journal, 1(4), 253–254.

Pulling the genome in opposite directions to dissect gene networks

Genome Biology, 19.

Pulling the genome in opposite directions to dissect gene networks

Genome Biology, 19(1).

The Democratization of CRISPR

The CRISPR Journal, 1(3), 203–204.

The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation

MSPHERE, 3(3).

Transcriptional and Functional Analysis of Bifidobacterium animalis subsp. lactis Exposure to Tetracycline

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 84(23).

Using glycolysis enzyme sequences to inform Lactobacillus phylogeny

Microbial Genomics, 4(6).

A decade of discovery: CRISPR functions and applications

NATURE MICROBIOLOGY, 2(7).

CRISPR-Cas Technologies and Applications in Food Bacteria

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 8, Vol. 8, pp. 413–437.

CRISPR-based engineering of next-generation lactic acid bacteria

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 79–87.

Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum

FRONTIERS IN MICROBIOLOGY, 8.

Deletion of Lipoteichoic Acid Synthase Impacts Expression of Genes Encoding Cell Surface Proteins in Lactobacillus acidophilus

Frontiers in Microbiology, 8.

Expanding the CRISPR Toolbox: Targeting RNA with Cas13b

Barrangou, R., & Gersbach, C. A. (2017, February 16). MOLECULAR CELL, Vol. 65, pp. 582–584.

Genome Editing of Food-Grade Lactobacilli To Develop Therapeutic Probiotics

Microbiology Spectrum, 5(5).

Guest editorial: CRISPRcas9: CRISPR-Cas systems: at the cutting edge of microbiology

Current Opinion in Microbiology, 37, vii-viii.

Immune Loss as a Driver of Coexistence During Host-Phage Coevolution

Weissman, J. L., Holmes, R., Barrangou, R., Moineau, S., Fagan, W. F., Levin, B., & Johnson, P. L. F. (2017, February 3). (Vol. 2). Vol. 2.

Investigating the Effect of Growth Phase on the Surface-Layer Associated Proteome of Lactobacillus acidophilus Using Quantitative Proteomics

FRONTIERS IN MICROBIOLOGY, 8.

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

MBIO, 8(6).

Les systèmes CRISPR-Cas comme arme contre les bactéries pathogènes

Biologie Aujourd'Hui, 211(4), 265–270.

On the global CRISPR array behavior in class I systems

BIOLOGY DIRECT, 12.

QnAs with Rodolphe Barrangou

Proceedings of the National Academy of Sciences, 114(28), 7183–7184.

Repurposing CRISPR-Cas systems as DNA-based smart antimicrobials

Cell and Gene Therapy Insights, 3(1), 63–72.

The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM

FRONTIERS IN MICROBIOLOGY, 8.

Using CRISPR-Cas systems as antimicrobials

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 155–160.

Applications of CRISPR technologies in research and beyond

[Review of ]. NATURE BIOTECHNOLOGY, 34(9), 933–941.

CRISPR Diversity and Microevolution in Clostridium difficile

GENOME BIOLOGY AND EVOLUTION, 8(9), 2841–2855.

CRISPR-Based Typing and Next-Generation Tracking Technologies

Annual Review of Food Science and Technology, 7(1), 395–411.

CRISPR-based typing and next-generation tracking technologies

[Review of ]. Annual review of food science and technology, vol 7, 7, 395–411.

Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(1), 134–145.

Deciphering and shaping bacterial diversity through CRISPR

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 31, 101–108.

Exploiting CRISPR-Cas immune systems for genome editing in bacteria

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 37, 61–68.

Functional Analysis of an S-Layer-Associated Fibronectin-Binding Protein in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(9), 2676–2685.

Genotyping by PCR and High-Throughput Sequencing of Commercial Probiotic Products Reveals Composition Biases

FRONTIERS IN MICROBIOLOGY, 7.

Guide RNAs: A Glimpse at the Sequences that Drive CRISPR–Cas Systems

Cold Spring Harbor Protocols, 2016(7), pdb.top090902.

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems

MOLECULAR CELL, 62(1), 137–147.

Metagenomic reconstructions of bacterial CRISPR loci constrain population histories

ISME JOURNAL, 10(4), 858–870.

Phylogenetic Analysis of the Bifidobacterium Genus Using Glycolysis Enzyme Sequences

FRONTIERS IN MICROBIOLOGY, 7.

Prediction and Validation of Native and Engineered Cas9 Guide Sequences

Cold Spring Harbor Protocols, 2016(7), pdb.prot086785.

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

NUCLEIC ACIDS RESEARCH, 43(7), 3407–3419.

An updated evolutionary classification of CRISPR-Cas systems

[Review of ]. Nature Reviews. Microbiology, 13(11), 722–736.

An updated evolutionary classification of CRISPR–Cas systems

Nature Reviews Microbiology, 13(11), 722–736.

Bacteriophage exclusion, a new defense system

Barrangou, R., & Oost, J. (2015, January 14). EMBO JOURNAL, Vol. 34, pp. 134–135.

CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

MBIO, 6(2).

CRISPR-Based Technologies and the Future of Food Science

Journal of Food Science, 80(11), R2367–R2372.

CRISPR-based screening of genomic island excision events in bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(26), 8076–8081.

Characterization and evolution of Salmonella CRISPR-Cas systems

MICROBIOLOGY-SGM, 161, 374–386.

Diversity of CRISPR-Cas immune systems and molecular machines

[Review of ]. Genome Biology, 16.

Diversity of CRISPR-Cas immune systems and molecular machines

Genome Biology, 16(1).

Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera

NATURE COMMUNICATIONS, 6.