Works (232)

Updated: February 15th, 2024 05:04

2023 journal article

Lactobacillus acidophilus Expressing Murine Rotavirus VP8 and Mucosal Adjuvants Induce Virus-Specific Immune Responses

VACCINES, 11(12).

By: D. Gilfillan*, A. Vilander*, M. Pan n, Y. Goh n, S. O'Flaherty n, N. Feng*, B. Fox*, C. Lang* ...

co-author countries: United States of America 🇺🇸
author keywords: rotavirus; Lactobacillus acidophilus; next-generation vaccine
Sources: ORCID, Web Of Science
Added: February 1, 2024

2023 article

Bile salt hydrolases shape the bile acid landscape and restrict Clostridioides difficile growth in the murine gut

Foley, M. H., Walker, M. E., Stewart, A. K., O'Flaherty, S., Gentry, E. C., Patel, S., … Theriot, C. M. (2023, March 13). NATURE MICROBIOLOGY, Vol. 3.

By: M. Foley n, M. Walker*, A. Stewart n, S. O'Flaherty n, E. Gentry*, S. Patel*, V. Beaty*, G. Allen n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Mice; Humans; Clostridioides difficile; Clostridioides; Bile Acids and Salts; Amidohydrolases; Clostridium Infections
Sources: Web Of Science, ORCID
Added: April 4, 2023

2023 article

CasPEDIA Database: a functional classification system for class 2 CRISPR-Cas enzymes

Adler, B. A., Trinidad, M. I., Bellieny-Rabelo, D., Zhang, E., Karp, H. M., Skopintsev, P., … Doudna, J. A. (2023, October 27). NUCLEIC ACIDS RESEARCH, Vol. 10.

co-author countries: Australia 🇦🇺 Lithuania 🇱🇹 Netherlands 🇳🇱 New Zealand 🇳🇿 United States of America 🇺🇸
Sources: ORCID, Web Of Science
Added: October 4, 2023

2023 journal article

Genome-Wide Comparative Analysis of Lactiplantibacillus pentosus Isolates Autochthonous to Cucumber Fermentation Reveals Subclades of Divergent Ancestry

FOODS, 12(13).

By: C. Page*, I. Perez-Diaz*, M. Pan n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactiplantibacillus pentosus; comparative genomics; Lactiplantibacillus plantarum; cucumber fermentation; starter culture
Sources: ORCID, Web Of Science
Added: June 23, 2023

2023 journal article

Impact of Pomegranate on Probiotic Growth, Viability, Transcriptome and Metabolism

MICROORGANISMS, 11(2).

By: S. O'Flaherty n, N. Cobian n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: probiotic; prebiotic; pomegranate; lactobacilli; transcriptomic
Sources: ORCID, Web Of Science
Added: February 7, 2023

2023 journal article

Mining microbial organisms to discover and characterize novel CRISPR-Cas systems

CURRENT OPINION IN BIOMEDICAL ENGINEERING, 27.

By: O. Raftopoulou n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Novel CRISPR-Cas; Discovery; Genome editing; Mining microbes; Mining metagenomes
Sources: ORCID, Web Of Science
Added: May 18, 2023

2023 journal article

Multiplex CRISPR editing of wood for sustainable fiber production

SCIENCE, 381(6654), 216-+.

By: D. Sulis n, X. Jiang n, C. Yang n, B. Marques n, M. Matthews n, Z. Miller n, K. Lan n, C. Cofre-Vega n ...

co-author countries: China 🇨🇳 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 9, 2023

2023 article

The Expanding Dissemination and Distribution Patterns of Diverse CRISPR Plasmids by Addgene

Pyhtila, B., Kasowitz, S., Leeson, R., & Barrangou, R. (2023, November 22). CRISPR JOURNAL, Vol. 11.

By: B. Pyhtila*, S. Kasowitz*, R. Leeson* & R. Barrangou n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: December 18, 2023

2022 article

Broad-spectrum CRISPR-Cas13a enables efficient phage genome editing

Adler, B. A., Hessler, T., Cress, B. F., Lahiri, A., Mutalik, V. K., Barrangou, R., … Doudna, J. A. (2022, October 31). NATURE MICROBIOLOGY, Vol. 10.

co-author countries: United States of America 🇺🇸
MeSH headings : Gene Editing; Bacteriophages / genetics; CRISPR-Cas Systems; Escherichia coli / genetics; Phylogeny; RNA / genetics; Antiviral Agents
Sources: ORCID, Web Of Science
Added: November 1, 2022

2022 journal article

CRISPR-based engineering of phages for in situ bacterial base editing

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(46).

By: M. Nethery n, C. Hidalgo-Cantabrana n, A. Roberts n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: phage engineering; CRISPR; base editing; soil microbiome
MeSH headings : Gene Editing; CRISPR-Cas Systems / genetics; Bacteriophages / genetics; Ecosystem; Soil
Sources: ORCID, Web Of Science
Added: November 8, 2022

2022 journal article

Clustered Regularly Interspaced Short Palindromic Repeats Genotyping of Multidrug-Resistant Salmonella Heidelberg Strains Isolated From the Poultry Production Chain Across Brazil

FRONTIERS IN MICROBIOLOGY, 13.

By: D. Monte*, M. Nethery n, H. Berman n, S. Keelara n, N. Lincopan*, P. Fedorka-Cray n, R. Barrangou n, M. Landgraf*

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: antibiotic resistance; CRISPR; phylogeny; Salmonella Heidelberg; foodborne disease; WGS
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 article

Functional characterization of diverse type I-F CRISPR-associated transposons

Roberts, A., Nethery, M. A., & Barrangou, R. (2022, November 17). NUCLEIC ACIDS RESEARCH, Vol. 11.

By: A. Roberts n, M. Nethery n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Plasmids; Endonucleases / metabolism; Escherichia coli / genetics; Escherichia coli / metabolism; DNA; RNA; CRISPR-Associated Proteins / genetics; CRISPR-Associated Proteins / metabolism
Sources: ORCID, Web Of Science
Added: October 19, 2022

2022 journal article

Genomic and epigenetic landscapes drive CRISPR-based genome editing in Bifidobacterium

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(30).

By: M. Pan n, W. Morovic*, C. Hidalgo-Cantabrana n, A. Roberts n, K. Walden*, Y. Goh n, R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas; bifidobacterium; genomics; epigenomics; probiotics
MeSH headings : Bifidobacterium / genetics; CRISPR-Cas Systems; Gene Editing / methods; Genome, Bacterial / genetics; Genomics; Humans; Probiotics
Sources: ORCID, Web Of Science
Added: July 21, 2022

2022 journal article

Metabolomic Analysis of Lactobacillus acidophilus, L. gasseri, L. crispatus, and Lacticaseibacillus rhamnosus Strains in the Presence of Pomegranate Extract

FRONTIERS IN MICROBIOLOGY, 13.

By: M. Chamberlain n, S. O'Flaherty n, N. Cobian n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: metabolomics; Lactobacillus; probiotic; pomegranate extract; prebiotic
Sources: Web Of Science, ORCID
Added: June 13, 2022

2022 article

Next-Generation Foods and CRISPR Engineering

Barrangou, R. (2022, August 11).

By: R. Barrangou n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: August 17, 2022

2022 article

RNA-targeting CRISPR-Cas13 Provides Broad-spectrum Phage Immunity

Adler, B. A., Hessler, T., Cress, B. F., Mutalik, V. K., Barrangou, R., Banfield, J., & Doudna, J. A. (2022, March 26). (Vol. 3). Vol. 3.

co-author countries: Australia 🇦🇺 United States of America 🇺🇸
Source: ORCID
Added: March 31, 2022

2022 article

Turning CRISPR on with antibiotics

Barrangou, R., & Marraffini, L. A. (2022, January 12). CELL HOST & MICROBE, Vol. 30, pp. 12–14.

By: R. Barrangou n & L. Marraffini*

co-author countries: United States of America 🇺🇸
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacteria / genetics; Base Sequence; CRISPR-Cas Systems; Viruses
Sources: Web Of Science, ORCID
Added: February 14, 2022

2021 journal article

(Broken) Promises of Sustainable Food and Agriculture through New Biotechnologies: The CRISPR Case

CRISPR JOURNAL, 4(1), 25–31.

By: T. Kuiken n, R. Barrangou n & K. Grieger n

co-author countries: United States of America 🇺🇸
MeSH headings : Agriculture; Animals; Biotechnology; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Crops, Agricultural / genetics; Food; Food Supply; Gene Editing; Livestock / genetics
Sources: Web Of Science, ORCID
Added: March 22, 2021

2021 article

Building a Resilient, Sustainable, and Healthier Food Supply Through Innovation and Technology

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 12, 2021, Vol. 12, pp. 1–28.

By: D. McClements*, R. Barrangou n, C. Hill*, J. Kokini*, M. Lila n, A. Meyer*, L. Yu*

co-author countries: Denmark 🇩🇰 Ireland 🇮🇪 United States of America 🇺🇸
author keywords: future foods; food production; food processing; environmental impacts; nanotechnology; gene editing; genetic engineering; artificial intelligence; robotics
MeSH headings : Agriculture; Artificial Intelligence; Biotechnology; COVID-19; Food Quality; Food Safety; Food Supply / standards; Humans; Nanotechnology; Pandemics; Robotics
Sources: Web Of Science, ORCID
Added: May 24, 2021

2021 journal article

CRISPRclassify: Repeat-Based Classification of CRISPR Loci

CRISPR JOURNAL, 4(4), 558–574.

By: M. Nethery n, M. Korvink*, K. Makarova*, Y. Wolf*, E. V. Koonin* & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Algorithms; Area Under Curve; Base Sequence; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Computational Biology / methods; Databases, Genetic; Gene Editing; Genetic Loci; Genome, Bacterial; Genomics / methods; Reproducibility of Results
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Comparative Genomic Analyses and CRISPR-Cas Characterization of Cutibacterium acnes Provide Insights Into Genetic Diversity and Typing Applications

FRONTIERS IN MICROBIOLOGY, 12.

By: N. Cobian n, A. Garlet*, C. Hidalgo-Cantabrana n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; genomics; Cas; genotyping; phylogeny
Sources: Web Of Science, ORCID
Added: November 29, 2021

2021 journal article

In Vivo Transcriptome of Lactobacillus acidophilus and Colonization Impact on Murine Host Intestinal Gene Expression

MBIO, 12(1).

By: Y. Goh n, R. Barrangou n & T. Klaenhammer n

co-author countries: United States of America 🇺🇸

Ed(s): G. Huffnagle

author keywords: Lactobacillus; acidophilus; gut adaptation; in vivo gene expression; mouse colonization; probiotic
MeSH headings : Animals; Bacterial Adhesion; Bacterial Proteins / genetics; Gene Expression Profiling; Host Microbial Interactions / genetics; Immunity; Intestines / microbiology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / physiology; Mice; Probiotics / administration & dosage; Sequence Analysis, RNA; Signal Transduction; Transcriptome
Sources: ORCID, Web Of Science
Added: January 26, 2021

2021 journal article

Lactobacillus bile salt hydrolase substrate specificity governs bacterial fitness and host colonization

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(6).

By: M. Foley n, S. O'Flaherty n, G. Allen n, A. Rivera n, A. Stewart n, R. Barrangou n, C. Theriot n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; Acidophilus; gasseri; bile salt hydrolase; bile acid
MeSH headings : Amidohydrolases / genetics; Amidohydrolases / metabolism; Ecosystem; Gastrointestinal Microbiome / genetics; Gastrointestinal Microbiome / physiology; Genetic Fitness / genetics; Host-Pathogen Interactions / genetics; Humans; Lactobacillus / enzymology; Lactobacillus / genetics; Probiotics / pharmacology; Substrate Specificity / genetics
Sources: ORCID, Web Of Science
Added: February 2, 2021

2021 journal article

Portable CRISPR-Cas9(N) System for Flexible Genome Engineering in Lactobacillus acidophilus, Lactobacillus gasseri, and Lactobacillus paracasei

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 87(6).

By: Y. Goh n & R. Barrangou n

co-author countries: United States of America 🇺🇸

Ed(s): E. Dudley

author keywords: Lactobacillus acidophilus; CRISPR; Cas9; nickase; genome editing; probiotic; lactic acid bacteria; Lactobacillus
MeSH headings : CRISPR-Associated Protein 9; CRISPR-Cas Systems; Deoxyribonuclease I; Gene Editing / methods; Genome, Bacterial; Lactobacillus acidophilus / genetics; Lactobacillus gasseri / genetics; Lacticaseibacillus paracasei / genetics
Sources: ORCID, Web Of Science
Added: February 26, 2021

2021 article

Species- and site-specific genome editing in complex bacterial communities

Rubin, B. E., Diamond, S., Cress, B. F., Crits-Christoph, A., Lou, Y. C., Borges, A. L., … Doudna, J. A. (2021, December 6). NATURE MICROBIOLOGY, Vol. 12.

By: B. Rubin*, S. Diamond*, B. Cress*, A. Crits-Christoph*, Y. Lou*, A. Borges*, H. Shivram*, C. He* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Archaea / genetics; Bacteria / classification; CRISPR-Cas Systems; Gastrointestinal Microbiome / genetics; Gene Editing / methods; Genome, Bacterial; Humans; Infant; Microbial Consortia / genetics; RNA, Guide, Kinetoplastida; Soil Microbiology
Sources: Web Of Science, ORCID
Added: December 13, 2021

2021 article

Todd R. Klaenhammer, an inspirational food microbiologist who leaves a lasting legacy

Barrangou, R., & Hill, C. (2021, June 1). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 118.

By: R. Barrangou n & C. Hill*

co-author countries: Ireland 🇮🇪 United States of America 🇺🇸
MeSH headings : Food Microbiology / history; History, 20th Century; History, 21st Century; Humans; Lactobacillales; National Academy of Sciences, U.S.; Probiotics / history; United States
Sources: ORCID, Web Of Science
Added: May 20, 2021

2021 article

Toward inclusive global governance of human genome editing

Yu, H., Xue, L., Barrangou, R., Chen, S., & Huang, Y. (2021, November 23). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 118.

By: H. Yu*, L. Xue*, R. Barrangou n, S. Chen* & Y. Huang*

co-author countries: Belgium 🇧🇪 China 🇨🇳 United States of America 🇺🇸
MeSH headings : Bioethics; Biomedical Research / ethics; CRISPR-Cas Systems; Clinical Governance / ethics; Clinical Governance / standards; Gene Editing / ethics; Genome, Human; Government; Humans; Publications
Sources: ORCID, Web Of Science
Added: November 18, 2021

2021 journal article

Whole-genome sequencing analysis and CRISPR genotyping of rare antibiotic-resistant Salmonella enterica serovars isolated from food and related sources

FOOD MICROBIOLOGY, 93.

By: D. Monte n, M. Nethery n, R. Barrangou n, M. Landgraf* & P. Fedorka-Cray n

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: Antibiotic resistance; CRISPR; Phylogeny; Salmonella serovars; Whole genome sequencing
MeSH headings : Anti-Bacterial Agents / pharmacology; Brazil; Clustered Regularly Interspaced Short Palindromic Repeats; Drug Resistance, Multiple, Bacterial / genetics; Food Microbiology; Genome, Bacterial; Genotype; Genotyping Techniques; Microbial Sensitivity Tests; Salmonella / classification; Salmonella / genetics; Salmonella / isolation & purification; Salmonella Food Poisoning; Salmonella enterica / classification; Salmonella enterica / drug effects; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Serogroup; Serotyping; Whole Genome Sequencing
Sources: Web Of Science, ORCID
Added: October 5, 2020

2020 journal article

Adaptive response to iterative passages of five Lactobacillus species in simulated vaginal fluid

BMC Microbiology, 20(1).

By: K. Brandt n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; Vaginal; Passages; Probiotics
MeSH headings : Adaptation, Physiological / genetics; Body Fluids / chemistry; Body Fluids / microbiology; Female; Genome, Bacterial; Genomic Instability; Humans; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / growth & development; Lactobacillus / physiology; Species Specificity; Transcriptome; Vagina / chemistry; Vagina / microbiology
Source: ORCID
Added: November 10, 2020

2020 journal article

Applications of CRISPR-Cas systems in lactic acid bacteria

FEMS Microbiology Reviews, 44(5), 523–537.

By: A. Roberts n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactic acid bacteria; CRISPR; Cas; genome editing; probiotics; genomics
MeSH headings : CRISPR-Cas Systems; Industrial Microbiology / trends; Lactobacillales / genetics; Microbiota / genetics
Source: ORCID
Added: May 21, 2020

2020 article

CRISPR Shields: Fending Off Diverse Cas Nucleases with Nucleus-like Structures

Barrangou, R., & Sontheimer, E. J. (2020, March 5). MOLECULAR CELL, Vol. 77, pp. 934–936.

By: R. Barrangou n & E. Sontheimer*

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteriophages / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; DNA; RNA
Sources: Web Of Science, ORCID
Added: April 6, 2020

2020 journal article

Characterization and applications of Type I CRISPR-Cas systems

Biochemical Society Transactions, 48(1), 15–23.

By: C. Hidalgo-Cantabrana n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptive Immunity; Animals; Bacteria / genetics; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Gene Editing / methods; Genome, Bacterial; Genome, Human; Humans; Plasmids / genetics
Source: ORCID
Added: January 11, 2020

2020 review

Combining omics technologies with CRISPR-based genome editing to study food microbes

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 61, 198–208.

By: M. Pan n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteria / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing; Probiotics
Sources: Web Of Science, ORCID
Added: May 8, 2020

2020 journal article

Comparative Analysis of Lactobacillus gasseri and Lactobacillus crispatus Isolated From Human Urogenital and Gastrointestinal Tracts

FRONTIERS IN MICROBIOLOGY, 10.

co-author countries: United States of America 🇺🇸
author keywords: probiotics; niche-specific adaptation; Lactobacillus; women's health; in vitro vaginal fluid model
Sources: Web Of Science, ORCID
Added: February 17, 2020

2020 journal article

Complete Genome Sequence of Lactobacillus johnsonii NCK2677, Isolated from Mice

Microbiology Resource Announcements, 9(43).

By: S. O'Flaherty n, M. Foley n, A. Rivera n, C. Theriot n & R. Barrangou n

co-author countries: United States of America 🇺🇸

Ed(s): D. Rasko

Source: ORCID
Added: October 22, 2020

2020 journal article

Comprehensive Mining and Characterization of CRISPR-Cas Systems in Bifidobacterium

Microorganisms, 8(5), 720.

By: M. Pan n, M. Nethery n, C. Hidalgo-Cantabrana n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Bifidobacterium; CRISPR-Cas; genomics
Source: ORCID
Added: May 29, 2020

2020 journal article

Deletion of S-Layer Associated Ig-Like Domain Protein Disrupts the Lactobacillus acidophilus Cell Surface

FRONTIERS IN MICROBIOLOGY, 11.

By: C. Klotz n, Y. Goh n, S. O'Flaherty n, B. Johnson n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; probiotic; S-layer; cell surface; S-layer associated protein; Ig-like domain
Sources: Web Of Science, ORCID
Added: April 27, 2020

2020 review

Evolutionary classification of CRISPR-Cas systems: a burst of class 2 and derived variants

[Review of ]. NATURE REVIEWS MICROBIOLOGY, 18(2), 67–83.

By: K. Makarova*, Y. Wolf*, J. Iranzo*, S. Shmakov*, O. Alkhnbashi*, S. Brouns*, E. Charpentier*, D. Cheng ...

co-author countries: Canada 🇨🇦 Germany 🇩🇪 Denmark 🇩🇰 Spain 🇪🇸 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Lithuania 🇱🇹 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Archaea / genetics; Bacteria / genetics; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / physiology; Evolution, Molecular; Gene Expression Regulation, Archaeal / physiology; Gene Expression Regulation, Bacterial / physiology
Sources: Web Of Science, ORCID
Added: February 27, 2020

2020 journal article

Genomic characterization of Lactobacillus fermentum DSM 20052

BMC Genomics, 21(1).

By: K. Brandt n, M. Nethery n, O. Sarah n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; Fermentum; Comparative genomics; CRISPR
MeSH headings : CRISPR-Cas Systems / genetics; Genetic Variation; Genome, Bacterial; Genomic Islands; Genomics; Interspersed Repetitive Sequences; Limosilactobacillus fermentum / classification; Limosilactobacillus fermentum / genetics; Phylogeny
Source: ORCID
Added: April 30, 2020

2020 journal article

Host and body site-specific adaptation of Lactobacillus crispatus genomes

NAR Genomics and Bioinformatics, 2(1).

By: M. Pan n, C. Hidalgo-Cantabrana n & R. Barrangou n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 24, 2020

2020 journal article

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

MBio, 11(2).

By: K. Selle, J. Fletcher n, H. Tuson, D. Schmitt, L. McMillan, G. Vridhambal, A. Rivera n, S. Montgomery* ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸

Ed(s): J. Ballard

MeSH headings : Animals; Bacteriophages / genetics; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems / genetics; Clostridioides difficile / genetics; Enterocolitis, Pseudomembranous / microbiology; Enterocolitis, Pseudomembranous / therapy; Female; Genetic Engineering; Male; Mice; Mice, Inbred C57BL
Source: ORCID
Added: March 10, 2020

2020 journal article

Reactions to the National Academies/Royal Society Report on Heritable Human Genome Editing

CRISPR JOURNAL, 3(5), 332–349.

By: M. Angrist, R. Barrangou*, F. Baylis, C. Brokowski, G. Burgio, A. Caplan, C. Chapman, G. Church ...

co-author countries: Switzerland 🇨🇭 United States of America 🇺🇸
MeSH headings : Academies and Institutes; Gene Editing / ethics; Genome, Human; Germ Cells; Human Experimentation / ethics; Humans; Research Report; Societies
Sources: Web Of Science, ORCID
Added: November 24, 2020

2020 journal article

S-layer associated proteins contribute to the adhesive and immunomodulatory properties of Lactobacillus acidophilus NCFM

BMC Microbiology, 20(1).

By: C. Klotz n, Y. Goh n, O. Sarah n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; S-layer; Probiotics; Cell surface
MeSH headings : Bacterial Adhesion; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Base Sequence; Caco-2 Cells; Catalytic Domain; Computer Simulation; Epithelial Cells / cytology; Epithelial Cells / immunology; Gene Deletion; Humans; Lactobacillus acidophilus / immunology; Lactobacillus acidophilus / physiology; Phenotype; Probiotics
Source: ORCID
Added: August 13, 2020

2020 journal article

Sharing the CRISPR Toolbox with an Expanding Community

CRISPR JOURNAL, 3(4), 248–252.

By: C. LaManna*, B. Pyhtila* & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing / statistics & numerical data; Gene Editing / trends
Sources: Web Of Science, ORCID
Added: September 14, 2020

2020 article

Shutting down RNA-targeting CRISPR

Barrangou, R., & Sontheimer, E. J. (2020, July 3). SCIENCE, Vol. 369, pp. 31–32.

By: R. Barrangou n & E. Sontheimer*

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteriophages; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; RNA
Sources: Web Of Science, ORCID
Added: August 3, 2020

2020 journal article

Strain-Dependent Inhibition of Clostridioides difficile by Commensal Clostridia Carrying the Bile Acid-Inducible ( bai ) Operon

Journal of Bacteriology, 202(11).

By: A. Reed n, M. Nethery n, A. Stewart n, R. Barrangou n & C. Theriot n

co-author countries: United States of America 🇺🇸

Ed(s): L. Comstock

author keywords: 7 alpha-dehydroxylation; Clostridia; Clostridioides difficile; bile acids; cholate; deoxycholate
MeSH headings : Antibiosis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bile Acids and Salts / metabolism; Clostridiales / genetics; Clostridiales / physiology; Clostridioides difficile / growth & development; Clostridioides difficile / physiology; Clostridium Infections / metabolism; Clostridium Infections / microbiology; Clostridium histolyticum / genetics; Clostridium histolyticum / physiology; Humans; Operon; Species Specificity; Symbiosis
Source: ORCID
Added: May 9, 2020

2020 article

Strain-dependent inhibition of Clostridioides difficile by commensal Clostridia encoding the bile acid inducible (bai) operon

Reed, A. D., Nethery, M. A., Stewart, A., Barrangou, R., & Theriot, C. M. (2020, January 23). (Vol. 1). Vol. 1.

By: A. Reed n, M. Nethery n, A. Stewart n, R. Barrangou n & C. Theriot n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 24, 2020

2019 article

Applications of CRISPR Technologies Across the Food Supply Chain

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 10, Vol. 10, pp. 133–150.

By: K. Brandt n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas; genome editing; crop development; food supply chain; livestock
MeSH headings : Animals; Clustered Regularly Interspaced Short Palindromic Repeats; Crops, Agricultural / genetics; Food Supply; Gene Editing; Livestock
Sources: Web Of Science, ORCID
Added: April 22, 2019

2019 journal article

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

PLOS PATHOGENS, 15(3).

By: M. Foley n, S. O'Flaherty n, R. Barrangou n & C. Theriot n

co-author countries: United States of America 🇺🇸

Ed(s): L. Knoll

MeSH headings : Amidohydrolases / metabolism; Amidohydrolases / physiology; Bile Acids and Salts / metabolism; Gastrointestinal Microbiome / physiology; Gastrointestinal Tract; Host Microbial Interactions / physiology; Humans
Sources: Web Of Science, ORCID
Added: April 15, 2019

2019 journal article

Bringing CRISPR to the Cinema

The CRISPR Journal, 2(4), 187–187.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
MeSH headings : CRISPR-Associated Proteins; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing; Motion Pictures
Source: ORCID
Added: January 3, 2020

2019 journal article

CRISPR Visualizer: rapid identification and visualization of CRISPR loci via an automated high-throughput processing pipeline

RNA BIOLOGY, 16(4), 577–584.

By: M. Nethery n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas; repeat detection; software; CRISPR spacer; crRNA
MeSH headings : Bacteria / genetics; Base Sequence; CRISPR-Cas Systems / genetics; Computational Biology; Genetic Loci; High-Throughput Nucleotide Sequencing / methods; Time Factors
Sources: Web Of Science, ORCID
Added: May 20, 2019

2019 journal article

CRISPR on the Move in 2019

The CRISPR Journal, 2(1), 1–2.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭 United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Humans; Research / trends
Source: ORCID
Added: January 3, 2020

2019 review

CRISPR-Directed Microbiome Manipulation across the Food Supply Chain

[Review of ]. TRENDS IN MICROBIOLOGY, 27(6), 489–496.

By: R. Barrangou n & R. Notebaart*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Fermentation; Food Chain; Food Microbiology; Food Supply; Gene Editing; Metabolic Engineering; Microbiota
Sources: Web Of Science, ORCID
Added: June 4, 2019

2019 review

Characterization and Repurposing of Type I and Type II CRISPR-Cas Systems in Bacteria

[Review of ]. JOURNAL OF MOLECULAR BIOLOGY, 431(1), 21–33.

By: C. Hidalgo-Cantabrana n, Y. Goh n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas systems; CRISPR characterization; endogenous systems; genome editing
Sources: Web Of Science, ORCID
Added: February 11, 2019

2019 article

Collaborative networks in gene editing

Huang, Y., Porter, A., Zhang, Y., & Barrangou, R. (2019, October). NATURE BIOTECHNOLOGY, Vol. 37, pp. 1107–1109.

By: Y. Huang*, A. Porter*, Y. Zhang* & R. Barrangou n

co-author countries: Australia 🇦🇺 Belgium 🇧🇪 China 🇨🇳 United States of America 🇺🇸
MeSH headings : Biomedical Research / trends; Gene Editing; Humans; International Cooperation; Leadership; Publishing / trends
Sources: Web Of Science, ORCID
Added: November 18, 2019

2019 journal article

Comparative genomics and evolution of trans-activating RNAs in Class 2 CRISPR-Cas systems

RNA BIOLOGY, 16(4), 435–448.

By: G. Faure*, S. Shmakov*, K. Makarova*, Y. Wolf*, A. Crawley n, R. Barrangou n, E. Koonin*

co-author countries: Russian Federation 🇷🇺 United States of America 🇺🇸
MeSH headings : Bacteroides / genetics; Base Sequence; CRISPR-Cas Systems / genetics; Conserved Sequence / genetics; Evolution, Molecular; Genomics; Nucleic Acid Conformation; RNA, Bacterial / genetics; RNA, Guide, Kinetoplastida / genetics; Repetitive Sequences, Nucleic Acid / genetics; Streptococcus / genetics; Thermodynamics; Trans-Activators / genetics
Sources: Web Of Science, ORCID
Added: May 20, 2019

2019 journal article

Comparative genomics of eight Lactobacillus buchneri strains isolated from food spoilage

BMC GENOMICS, 20(1).

By: M. Nethery n, E. Henriksen n, K. Daughtry n, S. Johanningsmeier n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus buchneri; Comparative genomics; Lactic acid bacteria; CRISPR-Cas systems; Fermentation; Spoilage; Food microbiology
MeSH headings : Computational Biology / methods; Evolution, Molecular; Fermentation; Food Microbiology; Genome, Bacterial; Genomics / methods; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Molecular Sequence Annotation; Phylogeny; Whole Genome Sequencing
Sources: Web Of Science, ORCID
Added: December 16, 2019

2019 journal article

Foresight is 2020: Ten Bold Predictions for the New CRISPR Year

The CRISPR Journal, 2(6), 341–342.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Gene Editing / ethics; Gene Editing / methods; Humans
Source: ORCID
Added: January 3, 2020

2019 journal article

Genome editing using the endogenous type I CRISPR-Cas system in Lactobacillus crispatus

Proceedings of the National Academy of Sciences.

By: C. Hidalgo-Cantabrana n, Y. Goh n, M. Pan n, R. Sanozky-Dawes n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; Cas3; type I-E; genome editing; probiotic
MeSH headings : Base Sequence; CRISPR-Cas Systems / genetics; Gene Editing; Genetic Loci; Genetic Variation; Lactobacillus crispatus / genetics; Lactobacillus crispatus / ultrastructure; Nucleotide Motifs / genetics; RNA, Guide, Kinetoplastida / genetics
Source: ORCID
Added: January 2, 2020

2019 review

Harnessing CRISPR-Cas systems for precision engineering of designer probiotic lactobacilli

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 56, 163–171.

By: Y. Goh n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems / genetics; Drug Delivery Systems; Gene Editing; Genetic Engineering / methods; Lactobacillus / genetics; Probiotics / metabolism
Sources: Web Of Science, ORCID
Added: June 17, 2019

2019 journal article

Outcomes and characterization of chromosomal self-targeting by native CRISPR-Cas systems in Streptococcus thermophilus

FEMS MICROBIOLOGY LETTERS, 366(9).

By: C. Canez n, K. Selle n, Y. Goh n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; lactic acid bacteria; Cas9; Streptococcus; genome editing
MeSH headings : Bacteriophages / genetics; CRISPR-Cas Systems; Chromosomes, Bacterial / genetics; Gene Editing; Genome, Bacterial; Homologous Recombination; Plasmids / genetics; Streptococcus thermophilus / genetics; Streptococcus thermophilus / virology
Sources: Web Of Science, ORCID
Added: September 3, 2019

2019 journal article

Partnering with bioRxiv

The CRISPR Journal, 2(6), 342–342.

By: R. Barrangou*

Source: ORCID
Added: January 3, 2020

2019 article

Predicting and visualizing features of CRISPR-Cas systems

CRISPR-CAS ENZYMES, Vol. 616, pp. 1–25.

By: M. Nethery n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bacteria / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Computer Simulation; Gene Editing / methods; Genomics / methods; Humans; RNA, Guide, Kinetoplastida / genetics; Software
Sources: Web Of Science, ORCID
Added: December 30, 2019

2019 journal article

Profile of Rodolphe Barrangou

Proceedings of the National Academy of Sciences, 116(32), 15754–15756.

By: T. Davis

MeSH headings : CRISPR-Cas Systems / genetics; Food Technology / history; History, 20th Century; History, 21st Century
Source: ORCID
Added: January 3, 2020

2019 journal article

Recombination between phages and CRISPR-cas loci facilitates horizontal gene transfer in staphylococci

NATURE MICROBIOLOGY, 4(6), 956–963.

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Bacteria / genetics; Bacteriophages / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / immunology; Endonucleases; Gene Transfer, Horizontal; Genome, Bacterial; Genome, Viral; Plasmids / genetics; Pseudomonas aeruginosa / genetics; Sequence Analysis, DNA; Staphylococcus / genetics; Staphylococcus aureus / genetics; Transduction, Genetic
Sources: Web Of Science, ORCID
Added: June 17, 2019

2019 journal article

Short communication: Transcriptional response to a large genomic island deletion in the dairy starter culture Streptococcus thermophilus

JOURNAL OF DAIRY SCIENCE, 102(9), 7800–7806.

By: K. Selle n, J. Andersen n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: fermentation; Streptococcus thermophilus; transcriptome; CRISPR
MeSH headings : Animals; Clustered Regularly Interspaced Short Palindromic Repeats; Fermentation; Gene Deletion; Gene Expression Regulation, Bacterial / physiology; Genomic Islands; Genomics; Lactic Acid / metabolism; Lactobacillus delbrueckii / metabolism; Milk / microbiology; Streptococcus thermophilus / genetics; Streptococcus thermophilus / metabolism; Transcriptome; Yogurt / microbiology
Sources: Web Of Science, ORCID
Added: August 26, 2019

2019 journal article

Taking CRISPR to New Heights

The CRISPR Journal, 2(3), 133–133.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
MeSH headings : CRISPR-Associated Proteins; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Editing
Source: ORCID
Added: January 3, 2020

2019 journal article

Targeted transcriptional modulation with type I CRISPR-Cas systems in human cells

NATURE BIOTECHNOLOGY, 37(12), 1493-+.

By: A. Pickar-Oliver*, J. Black*, M. Lewis*, K. Mutchnick*, T. Klann*, K. Gilcrest*, M. Sitton*, C. Nelson* ...

co-author countries: Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems / genetics; Escherichia coli / genetics; Genetic Engineering / methods; HEK293 Cells; Humans; Listeria monocytogenes / genetics; RNA, Guide, Kinetoplastida / genetics; Transcription, Genetic / genetics
Sources: Web Of Science, ORCID
Added: December 30, 2019

2019 journal article

The repurposing of type I-E CRISPR-Cascade for gene activation in plants

Communications Biology.

By: J. Young*, S. Gasior*, S. Jones*, L. Wang*, P. Navarro*, B. Vickroy*, R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Biolistics; CRISPR-Cas Systems; Chromosomes, Plant / genetics; DNA, Plant / genetics; Genes, Plant; Genetic Engineering / methods; Plasmids / genetics; Streptococcus thermophilus / genetics; Transcriptional Activation; Zea mays / embryology; Zea mays / genetics
Source: ORCID
Added: January 2, 2020

2019 journal article

Thinking About CRISPR: The Ethics of Human Genome Editing

The CRISPR Journal, 2(5), 247–248.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Gene Editing / ethics; Genome, Human / genetics; Humans
Source: ORCID
Added: January 3, 2020

2019 journal article

Time To Let CRISPR B.E.?

The CRISPR Journal, 2(2), 67–67.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
MeSH headings : Animals; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genetic Engineering / methods; Humans; Nucleotides / genetics; Research / trends
Source: ORCID
Added: January 3, 2020

2018 review

Advances in Industrial Biotechnology Using CRISPR-Cas Systems

[Review of ]. TRENDS IN BIOTECHNOLOGY, 36(2), 134–146.

By: P. Donohoue*, R. Barrangou n & A. May*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Biotechnology / methods; CRISPR-Associated Protein 9; CRISPR-Cas Systems; Endonucleases / genetics; Endonucleases / metabolism; Gene Editing / methods; Genetic Engineering / methods; Industrial Microbiology / methods; Metabolic Networks and Pathways / genetics; Plants / genetics; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

CRISPR Craziness: A Response to the EU Court Ruling

The CRISPR Journal, 1(4), 251–252.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Source: ORCID
Added: January 3, 2020

2018 journal article

CRISPR Crossroads for Genome Editing

The CRISPR Journal, 1(6), 349–350.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Source: ORCID
Added: January 3, 2020

2018 journal article

CRISPRdisco: An Automated Pipeline for the Discovery and Analysis of CRISPR-Cas Systems

CRISPR JOURNAL, 1(2), 171–181.

By: A. Crawley n, J. Henriksan & R. Barranaou

co-author countries: United States of America 🇺🇸
Sources: ORCID, Web Of Science
Added: February 25, 2019

2018 journal article

Characterizing the activity of abundant, diverse and active CRISPR-Cas systems in lactobacilli

Scientific Reports, 8(1).

By: A. Crawley n, E. Henriksen n, E. Stout n, K. Brandt n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteriophages / genetics; CRISPR-Cas Systems; Gene Expression Profiling; Genetic Variation; Genome, Bacterial; Lactobacillus / enzymology; Lactobacillus / genetics; Plasmids; RNA, Guide, Kinetoplastida / genetics; Recombination, Genetic
Sources: ORCID, Crossref
Added: January 2, 2020

2018 journal article

Conserved Genome Organization and Core Transcriptome of the Lactobacillus acidophilus Complex

FRONTIERS IN MICROBIOLOGY, 9.

By: A. Crawley n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; core genome; core transcriptome; microbial genetics; chromosome organization
Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 journal article

Cultivating CRISPR

The CRISPR Journal, 1(2), 99–100.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Source: ORCID
Added: January 3, 2020

2018 journal article

Deletion-based escape of CRISPR-Cas9 targeting in Lactobacillus gasseri

MICROBIOLOGY-SGM, 164(9), 1098–1111.

By: E. Stout n, R. Sanozky-Dawes n, Y. Goh n, A. Crawley n, T. Klaenhammer n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; CRISPR; Cas; Cas9; interference; spacer
MeSH headings : CRISPR-Associated Protein 9 / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats; Interspersed Repetitive Sequences; Lactobacillus gasseri / genetics; Mutation; Plasmids; Recombination, Genetic; Sequence Deletion; Transformation, Bacterial
Sources: Web Of Science, ORCID
Added: December 31, 2018

2018 journal article

Enabling the Rise of a CRISPR World

The CRISPR Journal, 1(3), 205–208.

By: C. LaManna n & R. Barrangou n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: February 18, 2019

2018 review

Engineering Components of the Lactobacillus S-Layer for Biotherapeutic Applications

[Review of ]. FRONTIERS IN MICROBIOLOGY, 9.

By: C. Klotz n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; probiotic; S-layer; biotherapeutic; mucosal vaccine; CRISPR
Sources: Web Of Science, ORCID
Added: October 16, 2018

2018 journal article

Expanding the CRISPR Landscape on a cas by cas Basis

The CRISPR Journal, 1(5), 303–303.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Source: ORCID
Added: January 3, 2020

2018 journal article

Immune loss as a driver of coexistence during host-phage coevolution

ISME JOURNAL, 12(2), 585–597.

By: J. Weissman*, R. Holmes*, R. Barrangou n, S. Moineau*, W. Fagan*, B. Levin*, P. Johnson*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Bacteria / genetics; Bacteria / immunology; Bacteriophages / physiology; Biological Evolution; CRISPR-Cas Systems; Models, Immunological
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 review

Insights into the Human Virome Using CRISPR Spacers from Microbiomes

[Review of ]. VIRUSES-BASEL, 10(9).

By: C. Hidalgo-Cantabrana n, R. Sanozky-Dawes n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR-Cas systems; CRISPR spacers; virome; phages; microbiome
MeSH headings : Biodiversity; Clustered Regularly Interspaced Short Palindromic Repeats; Humans; Metagenomics; Microbiota; Viruses / classification; Viruses / genetics; Viruses / isolation & purification
Sources: Web Of Science, ORCID
Added: November 26, 2018

2018 article

Keep Calm and CRISPR On

Barrangou, R. (2018, February). CRISPR JOURNAL, Vol. 1, pp. 1–3.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Sources: Web Of Science, ORCID
Added: February 25, 2019

2018 journal article

Lactobacillus gasseri CRISPR-Cas9 characterization In Vitro reveals a flexible mode of protospacer-adjacent motif recognition

PLOS ONE, 13(2).

By: E. Anderson*, S. McClelland*, E. Maksimova*, Z. Strezoska*, M. Basila*, A. Briner n, R. Barrangou n, A. Smith*

co-author countries: United States of America 🇺🇸

Ed(s): S. Xu

MeSH headings : CRISPR-Cas Systems; Lactobacillus gasseri / genetics; RNA Editing
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

MasterChef at Work: An Interview with Rodolphe Barrangou

The CRISPR Journal, 1(3), 219–222.

By: K. Davies* & R. Barrangou*

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 3, 2020

2018 article

Mining for novel bacterial defence systems

Barrangou, R., & Oost, J. (2018, May). NATURE MICROBIOLOGY, Vol. 3, pp. 535–536.

By: R. Barrangou n & J. Oost*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Bacteria; Genome, Bacterial
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Phenotypic and genotypic diversity of Lactobacillus buchneri strains isolated from spoiled, fermented cucumber

INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 280, 46–56.

By: K. Daughtry n, S. Johanningsmeier n, R. Sanozky-Dawes n, T. Klaenhammer n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactic acid bacteria; Pickled vegetables; Spoilage organisms; Lactobacillus buchneri; Strain diversity
MeSH headings : Acetic Acid / metabolism; Bioreactors; Cucumis sativus / microbiology; Fermentation; Genotype; Lactic Acid / metabolism; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Lactobacillus / metabolism; Propylene Glycol / metabolism; RNA, Ribosomal, 16S / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Pomp and Circumstance: Making the Case for CRISPR

The CRISPR Journal, 1(4), 253–254.

By: C. Curchoe* & R. Barrangou*

co-author countries: Switzerland 🇨🇭 United States of America 🇺🇸
Source: ORCID
Added: January 3, 2020

2018 journal article

Pulling the genome in opposite directions to dissect gene networks

Genome Biology, 19(1).

By: C. Gersbach* & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Associated Protein 9; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Regulatory Networks; Genome
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2018 journal article

Pulling the genome in opposite directions to dissect gene networks

Genome Biology, 19.

By: C. Gersbach & R. Barrangou

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

The Democratization of CRISPR

The CRISPR Journal, 1(3), 203–204.

By: R. Barrangou*

co-author countries: Switzerland 🇨🇭
Source: ORCID
Added: January 3, 2020

2018 journal article

The Lactobacillus Bile Salt Hydrolase Repertoire Reveals Niche-Specific Adaptation

MSPHERE, 3(3).

By: S. O'Flaherty n, A. Crawley n, C. Theriot n & R. Barrangou n

co-author countries: United States of America 🇺🇸

Ed(s): C. Ellermeier

author keywords: Lactobacillus; bile acid; bile salt hydrolase; gastrointestinal tract; niche; penicillin V acylase; probiotic; therapeutic
MeSH headings : Adaptation, Biological; Amidohydrolases / genetics; Genetic Variation; Genotype; Lactobacillus / classification; Lactobacillus / enzymology; Lactobacillus / genetics; Penicillin Amidase / genetics; Phylogeny; Sequence Homology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Transcriptional and Functional Analysis of Bifidobacterium animalis subsp. lactis Exposure to Tetracycline

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 84(23).

co-author countries: United States of America 🇺🇸

Ed(s): V. Müller

author keywords: Bifidobacterium animalis subsp. lactis; antibiotic resistance; tetracycline; RNA sequencing; genomics; droplet digital PCR; ATP luminescence
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Bifidobacterium animalis / drug effects; Bifidobacterium animalis / genetics; Bifidobacterium animalis / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats / drug effects; Gene Expression Regulation, Bacterial / drug effects; Genome, Bacterial / drug effects; Tetracycline / pharmacology; Tetracycline Resistance; Transcription, Genetic / drug effects
Sources: Web Of Science, ORCID
Added: December 3, 2018

2018 journal article

Using glycolysis enzyme sequences to inform Lactobacillus phylogeny

Microbial Genomics, 4(6).

By: K. Brandt n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; phylogeny; glycolysis; evolution
MeSH headings : Base Composition; Evolution, Molecular; Gene Expression Regulation, Bacterial; Genetic Drift; Genome Size; Genome, Bacterial; Glycolysis / genetics; Glycolysis / physiology; Lactobacillus / classification; Lactobacillus / enzymology; Lactobacillus / genetics; Lactobacillus / metabolism; Probiotics; RNA, Ribosomal, 16S / genetics; Sequence Alignment; Species Specificity
Source: ORCID
Added: January 3, 2020

2017 journal article

A decade of discovery: CRISPR functions and applications

NATURE MICROBIOLOGY, 2(7).

By: R. Barrangou n & P. Horvath*

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : Archaea / enzymology; Archaea / genetics; Bacteria / enzymology; Bacteria / genetics; CRISPR-Cas Systems; Gene Editing / history; Gene Editing / methods; History, 21st Century; Molecular Biology / history; Molecular Biology / methods
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 article

CRISPR-Cas Technologies and Applications in Food Bacteria

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 8, Vol. 8, pp. 413–437.

By: E. Stout n, T. Klaenhammer n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: probiotics; cultures; strain-typing; phage resistance; plasmid vaccination; antimicrobial; genome editing
MeSH headings : Bacteria / genetics; Bacteria / immunology; Bacterial Vaccines; Bacteriophages / genetics; CRISPR-Cas Systems; Food Industry; Food Microbiology; Gene Editing; Genes, Bacterial; Interspersed Repetitive Sequences; Probiotics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 review

CRISPR-based engineering of next-generation lactic acid bacteria

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 79–87.

By: C. Hidalgo-Cantabrana n, S. O'Flaherty n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Bifidobacterium / genetics; Bifidobacterium / physiology; CRISPR-Cas Systems; Food Microbiology / methods; Gene Editing; Humans; Lactobacillus / genetics; Lactobacillus / physiology; Metabolic Engineering; Probiotics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Characterization and Exploitation of CRISPR Loci in Bifidobacterium longum

FRONTIERS IN MICROBIOLOGY, 8.

By: C. Hidalgo-Cantabrana n, A. Crawley n, B. Sanchez* & R. Barrangou n

co-author countries: Spain 🇪🇸 United States of America 🇺🇸
author keywords: CRISPR-Cas systems; genotyping; probiotics; Bifidobacterium longum
Sources: ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

Deletion of Lipoteichoic Acid Synthase Impacts Expression of Genes Encoding Cell Surface Proteins in Lactobacillus acidophilus

Frontiers in Microbiology, 8.

By: K. Selle n, Y. Goh n, B. Johnson n, O. Sarah n, J. Andersen n, R. Barrangou n, T. Klaenhammer n

co-author countries: United States of America 🇺🇸
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 article

Expanding the CRISPR Toolbox: Targeting RNA with Cas13b

Barrangou, R., & Gersbach, C. A. (2017, February 16). MOLECULAR CELL, Vol. 65, pp. 582–584.

By: R. Barrangou n & C. Gersbach*

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Humans; RNA; RNA, Guide, Kinetoplastida / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Genome Editing of Food-Grade Lactobacilli To Develop Therapeutic Probiotics

Microbiology Spectrum, 5(5).

By: J. Pijkeren* & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Bacterial Infections / drug therapy; Gene Editing; Genome, Bacterial; Humans; Lactobacillus / genetics; Lactobacillus / physiology; Probiotics / chemistry; Probiotics / therapeutic use
Source: ORCID
Added: January 3, 2020

2017 journal article

Guest editorial: CRISPRcas9: CRISPR-Cas systems: at the cutting edge of microbiology

Current Opinion in Microbiology, 37, vii-viii.

By: R. Barrangou n & D. Bikard*

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : Bacteria / genetics; Bacteria / immunology; Biotechnology / trends; CRISPR-Associated Proteins / metabolism; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; Gene Editing; Microbiology / trends; Quorum Sensing
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2017 article

Immune Loss as a Driver of Coexistence During Host-Phage Coevolution

Weissman, J. L., Holmes, R., Barrangou, R., Moineau, S., Fagan, W. F., Levin, B., & Johnson, P. L. F. (2017, February 3). (Vol. 2). Vol. 2.

By: J. Weissman*, R. Holmes*, R. Barrangou n, S. Moineau*, W. Fagan*, B. Levin*, P. Johnson*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
Source: ORCID
Added: January 2, 2020

2017 journal article

Investigating the Effect of Growth Phase on the Surface-Layer Associated Proteome of Lactobacillus acidophilus Using Quantitative Proteomics

FRONTIERS IN MICROBIOLOGY, 8.

By: C. Klotz n, S. O'Flaherty n, Y. Goh n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Lactobacillus; probiotic; cell surface; S-layer; quantitative proteomics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Lactobacillus acidophilus Metabolizes Dietary Plant Glucosides and Externalizes Their Bioactive Phytochemicals

MBIO, 8(6).

By: M. Theilmann*, Y. Goh n, K. Nielsen*, T. Klaenhammer n, R. Barrangou n & M. Abou Hachem*

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸

Ed(s): E. Martens & M. McFall-Ngai

author keywords: Lactobacillus; beta-glucoside; bioavailability; gut microbiota; phytochemical; polydatin; polyphenols; resveratrol; xenobiotic metabolism
MeSH headings : Biological Availability; Dietary Carbohydrates / metabolism; Gastrointestinal Microbiome / physiology; Glucosides / metabolism; Glucosides / pharmacology; Humans; Hydrolysis; Lactobacillus acidophilus / drug effects; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Lactobacillus acidophilus / metabolism; Phytochemicals / metabolism; Polyphenols / metabolism; Resveratrol; Stilbenes / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Les systèmes CRISPR-Cas comme arme contre les bactéries pathogènes

Biologie Aujourd'Hui, 211(4), 265–270.

By: D. Bikard* & R. Barrangou n

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : Animals; Anti-Bacterial Agents / metabolism; Bacteria / immunology; Bacteria / pathogenicity; CRISPR-Cas Systems / physiology; Cell Death / genetics; Deoxyribonucleases / genetics; Deoxyribonucleases / metabolism; Disease Resistance / genetics; Humans; Immunity, Innate / genetics
Sources: ORCID, Crossref
Added: January 3, 2020

2017 journal article

On the global CRISPR array behavior in class I systems

BIOLOGY DIRECT, 12.

By: A. Toms n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems / physiology; Chromosomes, Bacterial / chemistry; Datasets as Topic; Genome, Bacterial; Models, Genetic; Poisson Distribution; Software
Sources: ORCID, Web Of Science
Added: August 6, 2018

2017 journal article

QnAs with Rodolphe Barrangou

Proceedings of the National Academy of Sciences, 114(28), 7183–7184.

By: P. Nair

MeSH headings : Animals; Bacteria / virology; Biotechnology / history; Biotechnology / methods; Biotechnology / trends; CRISPR-Cas Systems; Drug Resistance, Bacterial; Food Contamination; Food Microbiology; Food Technology; Genotype; History, 21st Century; Livestock; Meat; Molecular Biology
Source: ORCID
Added: January 2, 2020

2017 journal article

Repurposing CRISPR-Cas systems as DNA-based smart antimicrobials

Cell and Gene Therapy Insights, 3(1), 63–72.

By: R. Barrangou* & D. Ousterout

Source: ORCID
Added: January 2, 2020

2017 journal article

The S-layer Associated Serine Protease Homolog PrtX Impacts Cell Surface-Mediated Microbe-Host Interactions of Lactobacillus acidophilus NCFM

FRONTIERS IN MICROBIOLOGY, 8.

By: B. Johnson n, S. O'Flaherty n, Y. Goh n, I. Carroll*, R. Barrangou n & T. Klaenhammer n

co-author countries: United States of America 🇺🇸
author keywords: serine protease; S-layer; S-layer associated proteins; Lactobacillus; probiotic; intestinal barrier integrity; mucin; fibronectin
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 review

Using CRISPR-Cas systems as antimicrobials

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 37, 155–160.

By: D. Bikard* & R. Barrangou n

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : Anti-Infective Agents / pharmacology; Biological Products / pharmacology; CRISPR-Cas Systems; DNA Cleavage; DNA, Bacterial / metabolism; Genetic Engineering; Microbial Viability / drug effects; Plasmids; Transformation, Bacterial
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 review

Applications of CRISPR technologies in research and beyond

[Review of ]. NATURE BIOTECHNOLOGY, 34(9), 933–941.

By: R. Barrangou n & J. Doudna*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

CRISPR Diversity and Microevolution in Clostridium difficile

GENOME BIOLOGY AND EVOLUTION, 8(9), 2841–2855.

By: J. Andersen n, M. Shoup*, C. Robinson*, R. Bitton, K. Olsen* & R. Barrangou n

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
author keywords: CRISPR-Cas; CRISPR phylogeny; CRISPR typing; BI/NAP1/RT027/ST1Type-IB
MeSH headings : CRISPR-Cas Systems; Clostridioides difficile / classification; Clostridioides difficile / genetics; Clustered Regularly Interspaced Short Palindromic Repeats; Evolution, Molecular; Phylogeny; Polymorphism, Genetic
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

CRISPR-Based Typing and Next-Generation Tracking Technologies

Annual Review of Food Science and Technology, 7(1), 395–411.

By: R. Barrangou n & E. Dudley*

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; cas; typing; epidemiology
MeSH headings : Bacteria / classification; Bacteria / genetics; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / physiology; Genome, Bacterial / genetics; Genotyping Techniques / methods; Genotyping Techniques / trends; Lactobacillus / classification; Lactobacillus / genetics; Salmonella / classification; Salmonella / genetics; Streptococcus thermophilus / classification; Streptococcus thermophilus / genetics
Source: ORCID
Added: January 2, 2020

2016 review

CRISPR-based typing and next-generation tracking technologies

[Review of ]. Annual review of food science and technology, vol 7, 7, 395–411.

By: R. Barrangou & E. Dudley

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Conserved S-Layer-Associated Proteins Revealed by Exoproteomic Survey of S-Layer-Forming Lactobacilli

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(1), 134–145.

By: B. Johnson n, J. Hymes n, R. Sanozky-Dawes n, E. Henriksen n, R. Barrangou n & T. Klaenhammer n

co-author countries: United States of America 🇺🇸

Ed(s): H. Nojiri

MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Lactobacillus / chemistry; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / metabolism; Lactobacillus acidophilus / chemistry; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Membrane Glycoproteins / chemistry; Membrane Glycoproteins / genetics; Membrane Glycoproteins / metabolism; Molecular Sequence Data; Phylogeny; Proteomics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 review

Deciphering and shaping bacterial diversity through CRISPR

[Review of ]. CURRENT OPINION IN MICROBIOLOGY, 31, 101–108.

By: A. Briner n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteria / genetics; Bacteria / virology; Bacteriophages / genetics; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genome, Bacterial / genetics; Host-Pathogen Interactions / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 review

Exploiting CRISPR-Cas immune systems for genome editing in bacteria

[Review of ]. CURRENT OPINION IN BIOTECHNOLOGY, 37, 61–68.

By: R. Barrangou n & J. Pijkeren*

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; DNA Repair; DNA, Bacterial / genetics; Genome, Bacterial; Humans; Immune System; Protein Engineering
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Functional Analysis of an S-Layer-Associated Fibronectin-Binding Protein in Lactobacillus acidophilus NCFM

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(9), 2676–2685.

By: J. Hymes n, B. Johnson n, R. Barrangou n & T. Klaenhammer n

co-author countries: United States of America 🇺🇸

Ed(s): E. Dudley

MeSH headings : Bacterial Adhesion / physiology; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Fibronectins / metabolism; Intestines / microbiology; Lactobacillus acidophilus / chemistry; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Membrane Glycoproteins / metabolism; Mutation; Phylogeny; Protein Binding
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Genotyping by PCR and High-Throughput Sequencing of Commercial Probiotic Products Reveals Composition Biases

FRONTIERS IN MICROBIOLOGY, 7.

By: W. Morovic*, A. Hibberd*, B. Zabel*, R. Barrangou n & B. Stahl*

co-author countries: United States of America 🇺🇸
author keywords: probiotics; labeling; testing and assessment; Lactobacillus; Bifidobacterium; multiplex PCR; taxonomy; high-throughput nucleotide sequencing
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Guide RNAs: A Glimpse at the Sequences that Drive CRISPR–Cas Systems

Cold Spring Harbor Protocols, 2016(7), pdb.top090902.

By: A. Briner n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; Gene Editing / methods; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism; Streptococcus pyogenes / enzymology
Source: ORCID
Added: January 2, 2020

2016 journal article

Identifying and Visualizing Functional PAM Diversity across CRISPR-Cas Systems

MOLECULAR CELL, 62(1), 137–147.

By: R. Leenay n, K. Maksimchuk n, R. Slotkowski n, R. Agrawal n, A. Gomaa n, A. Briner n, R. Barrangou n, C. Beisel n

co-author countries: Egypt 🇪🇬 United States of America 🇺🇸
MeSH headings : Bacillus / chemistry; Bacillus / metabolism; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Cas Systems; Escherichia coli / chemistry; Escherichia coli / metabolism; Francisella / chemistry; Francisella / metabolism; High-Throughput Screening Assays / methods; Protein Structure, Tertiary; Streptococcus thermophilus / chemistry; Streptococcus thermophilus / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Metagenomic reconstructions of bacterial CRISPR loci constrain population histories

ISME JOURNAL, 10(4), 858–870.

By: C. Sun*, B. Thomas*, R. Barrangou n & J. Banfield*

co-author countries: United States of America 🇺🇸
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / virology; Bacteriophages / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Metagenomics; Plasmids
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Phylogenetic Analysis of the Bifidobacterium Genus Using Glycolysis Enzyme Sequences

FRONTIERS IN MICROBIOLOGY, 7.

By: K. Brandt n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: Bifidobacterium; glycolysis; phylogeny; probiotic; evolution
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Prediction and Validation of Native and Engineered Cas9 Guide Sequences

Cold Spring Harbor Protocols, 2016(7), pdb.prot086785.

By: A. Briner n, E. Henriksen n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Bacterial Proteins / metabolism; CRISPR-Associated Protein 9; Endonucleases / metabolism; Gene Editing / methods; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / metabolism; Streptococcus pyogenes / enzymology
Source: ORCID
Added: January 2, 2020

2015 journal article

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference

NUCLEIC ACIDS RESEARCH, 43(7), 3407–3419.

By: R. Barrangou n, A. Birmingham, S. Wiemann*, R. Beijersbergen*, V. Hornung* & A. Smith

co-author countries: Germany 🇩🇪 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Animals; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Genetic Engineering; Genome; RNA Interference
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 review

An updated evolutionary classification of CRISPR-Cas systems

[Review of ]. Nature Reviews. Microbiology, 13(11), 722–736.

By: K. Makarova, Y. Wolf, O. Alkhnbashi, F. Costa, S. Shah, S. Saunders, R. Barrangou, S. Brouns ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

An updated evolutionary classification of CRISPR–Cas systems

Nature Reviews Microbiology, 13(11), 722–736.

co-author countries: Canada 🇨🇦 Germany 🇩🇪 Denmark 🇩🇰 Spain 🇪🇸 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Archaea / genetics; Bacteria / genetics; CRISPR-Cas Systems / genetics; Evolution, Molecular; Genome, Archaeal; Genome, Bacterial; Phylogeny
Sources: ORCID, Crossref
Added: January 2, 2020

2015 article

Bacteriophage exclusion, a new defense system

Barrangou, R., & Oost, J. (2015, January 14). EMBO JOURNAL, Vol. 34, pp. 134–135.

By: R. Barrangou n & J. Oost*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Bacillus subtilis / virology; Bacteriophages / genetics; Bacteriophages / pathogenicity; DNA Methylation; DNA Modification Methylases / genetics; Genome, Microbial; Virulence / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

CRISPR Immunity Drives Rapid Phage Genome Evolution in Streptococcus thermophilus

MBIO, 6(2).

By: D. Paez-Espino*, I. Sharon*, W. Morovic*, B. Stahl*, B. Thomas*, R. Barrangou n, J. Banfield*

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptation, Biological; CRISPR-Cas Systems; Evolution, Molecular; Genome, Viral; Host-Parasite Interactions; Mutation Rate; Polymorphism, Single Nucleotide; Recombination, Genetic; Streptococcus thermophilus / genetics; Streptococcus thermophilus / virology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

CRISPR-Based Technologies and the Future of Food Science

Journal of Food Science, 80(11), R2367–R2372.

By: K. Selle n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; genome; microbiology
MeSH headings : Bacteria / genetics; Bacteria / virology; Bacteriophages; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Fermentation; Food Technology; Humans; Probiotics
Source: ORCID
Added: January 2, 2020

2015 journal article

CRISPR-based screening of genomic island excision events in bacteria

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(26), 8076–8081.

By: K. Selle n, T. Klaenhammer n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: CRISPR; lactic acid bacteria; transposons; IS-elements; Cas9
MeSH headings : Clustered Regularly Interspaced Short Palindromic Repeats; Gene Deletion; Genome, Bacterial; Homeostasis; Homologous Recombination; Streptococcus thermophilus / genetics; Streptococcus thermophilus / growth & development
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Characterization and evolution of Salmonella CRISPR-Cas systems

MICROBIOLOGY-SGM, 161, 374–386.

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Diversity of CRISPR-Cas immune systems and molecular machines

Genome Biology, 16(1).

By: R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptive Immunity / genetics; Animals; Bacteria / genetics; Bacteria / immunology; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; DNA / genetics; Genetic Engineering / methods; Genetic Variation / genetics; Genetic Variation / immunology; Humans; RNA Editing / genetics
Source: ORCID
Added: January 2, 2020

2015 review

Diversity of CRISPR-Cas immune systems and molecular machines

[Review of ]. Genome Biology, 16.

By: R. Barrangou

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Expanding the biotechnology potential of lactobacilli through comparative genomics of 213 strains and associated genera

NATURE COMMUNICATIONS, 6.

By: Z. Sun*, H. Harris*, A. McCann*, C. Guo*, S. Argimon*, W. Zhang*, X. Yang*, I. Jeffery* ...

co-author countries: China 🇨🇳 Finland 🇫🇮 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Ireland 🇮🇪 Italy 🇮🇹 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Biotechnology; Genome, Bacterial; Lactobacillus / enzymology; Lactobacillus / genetics; Leuconostoc / genetics; Pediococcus / genetics; Phylogeny; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 review

Harnessing CRISPR-Cas systems for bacterial genome editing

[Review of ]. TRENDS IN MICROBIOLOGY, 23(4), 225–232.

By: K. Selle n & R. Barrangou n

co-author countries: United States of America 🇺🇸
author keywords: genome editing; CRISPR-Cas; Cas9
MeSH headings : Bacteria / genetics; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats; DNA Repair; Genetic Engineering / methods; Genome, Bacterial; Homeostasis / genetics; Mutation; Phenotype
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

JFS Special Issue: 75 years of advancing food science, and preparing for the next 75 CRISPR-based technologies and the future of food science

Journal of Food Science, 80(11), R2367–2372.

By: K. Selle & R. Barrangou

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Microbial Ecology of Watery Kimchi

JOURNAL OF FOOD SCIENCE, 80(5), M1031–M1038.

By: K. Kyung*, E. Medina Pradas, S. Kim*, Y. Lee*, K. Kim*, J. Choi*, J. Cho*, C. Chung*, R. Barrangou n, F. Breidt n

co-author countries: Spain 🇪🇸 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: high-throughput sequencing; microbial ecology; watery kimchi
MeSH headings : DNA, Bacterial / chemistry; DNA, Bacterial / classification; DNA, Bacterial / isolation & purification; DNA, Ribosomal / chemistry; Enterobacteriaceae / classification; Enterobacteriaceae / genetics; Enterobacteriaceae / isolation & purification; Fermentation; Food Microbiology; Lactobacillus / classification; Proteobacteria / classification; Proteobacteria / genetics; Proteobacteria / isolation & purification; RNA, Ribosomal, 16S / genetics; Raphanus / microbiology; Sequence Analysis, DNA; Temperature; Vegetables / microbiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Occurrence and Diversity of CRISPR-Cas Systems in the Genus Bifidobacterium

PLOS ONE, 10(7).

co-author countries: Spain 🇪🇸 Ireland 🇮🇪 Italy 🇮🇹 United States of America 🇺🇸

Ed(s): C. Riedel

MeSH headings : Bifidobacterium / genetics; CRISPR-Cas Systems / genetics; Chromosomes, Bacterial / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; DNA / genetics; Evolution, Molecular; Genetic Variation / genetics; Genome, Bacterial / genetics; Prophages / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Occurrence and activity of a type II CRISPR-Cas system in Lactobacillus gasseri

MICROBIOLOGY-SGM, 161, 1752–1761.

By: R. Sanozky-Dawes n, K. Selle n, S. O'Flaherty n, T. Klaenhammer n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Base Sequence; CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats; Gene Order; Genome, Bacterial; Lactobacillus / genetics; Molecular Sequence Data; Plasmids / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 review

The Bacterial Origins of the CRISPR Genome-Editing Revolution

[Review of ]. HUMAN GENE THERAPY, 26(7), 413–424.

By: E. Sontheimer* & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Archaea / genetics; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; Genetic Engineering / economics; Genetic Engineering / trends; Genome, Bacterial; Humans
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 review

The roles of CRISPR-Cas systems in adaptive immunity and beyond

[Review of ]. CURRENT OPINION IN IMMUNOLOGY, 32, 36–41.

By: R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Archaea / immunology; Bacteria / immunology; Bacterial Physiological Phenomena; Biological Evolution; CRISPR-Cas Systems / physiology; Gene Expression Regulation, Bacterial; Genome, Bacterial; Transcription, Genetic
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 article

Unraveling the potential of CRISPR-Cas9 for gene therapy

Barrangou, R., & May, A. P. (2015, March). EXPERT OPINION ON BIOLOGICAL THERAPY, Vol. 15, pp. 311–314.

By: R. Barrangou n & A. May*

co-author countries: United States of America 🇺🇸
author keywords: Cas9; CRISPR; gene therapy; genome editing
MeSH headings : Animals; CRISPR-Cas Systems / genetics; DNA Repair / genetics; Genetic Therapy / methods; Genetic Therapy / trends; Genome; Humans
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 article

A CRISPR design for next-generation antimicrobials

GENOME BIOLOGY, Vol. 15.

By: C. Beisel n, A. Gomaa n & R. Barrangou n

co-author countries: Egypt 🇪🇬 United States of America 🇺🇸
MeSH headings : Animals; Anti-Infective Agents / administration & dosage; CRISPR-Cas Systems; Drug Resistance, Microbial / genetics; Enterohemorrhagic Escherichia coli / genetics; Gene Targeting; RNA, Guide, Kinetoplastida / genetics; Ribonucleases / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Association of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Elements with Specific Serotypes and Virulence Potential of Shiga Toxin-Producing Escherichia coli

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(4), 1411–1420.

By: M. Toro*, G. Cao*, W. Ju*, M. Allard*, R. Barrangou n, S. Zhao*, E. Brown*, J. Meng*

co-author countries: United States of America 🇺🇸
MeSH headings : Cluster Analysis; Clustered Regularly Interspaced Short Palindromic Repeats; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Genotype; Molecular Sequence Data; Sequence Analysis, DNA; Serotyping; Shiga-Toxigenic Escherichia coli / classification; Shiga-Toxigenic Escherichia coli / genetics; Shiga-Toxigenic Escherichia coli / pathogenicity; Virulence Factors / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 review

CRISPR-Cas Systems: Prokaryotes Upgrade to Adaptive Immunity

[Review of ]. MOLECULAR CELL, 54(2), 234–244.

By: R. Barrangou n & L. Marraffini*

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptive Immunity / genetics; Bacteriophages / immunology; CRISPR-Associated Proteins / immunology; Clustered Regularly Interspaced Short Palindromic Repeats / immunology; DNA, Bacterial / chemistry; Inverted Repeat Sequences; Prokaryotic Cells / immunology; Prokaryotic Cells / virology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 article

Cas9 Targeting and the CRISPR Revolution

Barrangou, R. (2014, May 16). SCIENCE, Vol. 344, pp. 707–708.

By: R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Clustered Regularly Interspaced Short Palindromic Repeats; DNA Cleavage; Gene Targeting / methods; Genetic Engineering / methods; RNA, Guide, Kinetoplastida / genetics; Streptococcus pyogenes / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 article

Functions and Applications of RNA-Guided CRISPR-Cas Immune Systems

Barrangou, R., & Horvath, P. (2014, October). Encyclopedia of Molecular Cell Biology and Molecular Medicine.

By: R. Barrangou n & P. Horvath*

co-author countries: France 🇫🇷 United States of America 🇺🇸
Source: ORCID
Added: January 2, 2020

2014 journal article

Genomic Encyclopedia of Type Strains of the Genus Bifidobacterium

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(20), 6290–6302.

By: C. Milani*, G. Lugli*, S. Duranti*, F. Turroni*, F. Bottacini*, M. Mangifesta*, B. Sanchez*, A. Viappiani* ...

co-author countries: Belgium 🇧🇪 Spain 🇪🇸 Ireland 🇮🇪 Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Animals; Bifidobacterium / genetics; Bifidobacterium / metabolism; Bifidobacterium / physiology; Biological Evolution; Clustered Regularly Interspaced Short Palindromic Repeats; Computer Simulation; Gastrointestinal Tract / microbiology; Genome, Bacterial; Molecular Sequence Data; Phylogeny; Sequence Analysis, DNA; Species Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Guide RNA Functional Modules Direct Cas9 Activity and Orthogonality

MOLECULAR CELL, 56(2), 333–339.

By: A. Briner n, P. Donohoue*, A. Gomaa n, K. Selle n, E. Slorach*, C. Nye*, R. Haurwitz*, C. Beisel n, A. May*, R. Barrangou n

co-author countries: Egypt 🇪🇬 United States of America 🇺🇸
MeSH headings : Bacterial Proteins / chemistry; CRISPR-Associated Protein 9; CRISPR-Associated Proteins / chemistry; CRISPR-Cas Systems; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / chemistry; DNA Cleavage; Endonucleases / chemistry; Genetic Engineering / methods; HEK293 Cells; Humans; Nucleic Acid Conformation; RNA, Guide, Kinetoplastida / chemistry; RNA, Guide, Kinetoplastida / genetics; RNA, Guide, Kinetoplastida / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Lactobacillus buchneri Genotyping on the Basis of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Locus Diversity

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 80(3), 994–1001.

By: A. Briner n & R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Clustered Regularly Interspaced Short Palindromic Repeats; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Food Microbiology; Genetic Variation; Genotype; Lactobacillus / classification; Lactobacillus / genetics; Lactobacillus / isolation & purification; Molecular Sequence Data; Molecular Typing / methods; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Microbiology: Bacteria get vaccinated

Nature, 513(7517), 175–176.

By: R. Barrangou n & T. Klaenhammer n

co-author countries: United States of America 🇺🇸
MeSH headings : Adaptive Immunity / immunology; Bacteriophages / immunology; CRISPR-Cas Systems / immunology; Streptococcus thermophilus / immunology
Sources: ORCID, NC State University Libraries
Added: August 6, 2018

2014 journal article

Programmable Removal of Bacterial Strains by Use of Genome-Targeting CRISPR-Cas Systems

MBIO, 5(1).

By: A. Gomaa n, H. Klumpe n, M. Luo n, K. Selle n, R. Barrangou n & C. Beisel n

co-author countries: United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems; DNA, Bacterial / genetics; DNA, Bacterial / metabolism; Escherichia coli / genetics; Genome, Bacterial; Hydrolysis; Microbial Viability
Sources: ORCID, Web Of Science
Added: August 6, 2018

2014 journal article

Short communication: Determination of Salmonella clustered regularly interspaced short palindromic repeats (CRISPR) diversity on dairy farms in Wisconsin and Minnesota

Journal of Dairy Science, 97(10), 6370–6377.

By: C. Wehnes*, T. Rehberger, R. Barrangou* & A. Smith

co-author countries: United States of America 🇺🇸
author keywords: salmonellosis; cow; clustered regularly interspaced short palindromic repeats (CRISPR)
MeSH headings : Animals; Base Sequence; Cattle; Cattle Diseases / epidemiology; Cattle Diseases / microbiology; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Dairying; Feces / microbiology; Female; Genetic Variation; Genotype; Humans; Minnesota / epidemiology; Molecular Sequence Data; Salmonella / genetics; Salmonella / isolation & purification; Salmonella Food Poisoning / epidemiology; Salmonella Food Poisoning / microbiology; Salmonella Infections, Animal / epidemiology; Salmonella Infections, Animal / microbiology; Sequence Analysis, DNA; Serogroup; Wisconsin / epidemiology
Source: ORCID
Added: January 2, 2020

2014 journal article

The evolutionary history and diagnostic utility of the CRISPR-Cas system within Salmonella enterica ssp enterica

PEERJ, 2.

By: J. Pettengill*, R. Timme*, R. Barrangou n, M. Toro*, M. Allard*, E. Strain*, S. Musser*, E. Brown*

co-author countries: United States of America 🇺🇸
author keywords: Salmonella; Horizontal gene transfer; Evolution; CRISPR; Outbreak; Phylogeny; Whole genome sequencing; Typing
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

The three major types of CRISPR-Cas systems function independently in CRISPR RNA biogenesis in Streptococcus thermophilus

MOLECULAR MICROBIOLOGY, 93(1), 98–112.

By: J. Carte*, R. Christopher*, J. Smith*, S. Olson*, R. Barrangou n, S. Moineau*, C. Glover*, B. Graveley*, R. Terns*, M. Terns*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Bacterial Proteins / metabolism; CRISPR-Cas Systems; Models, Genetic; RNA, Bacterial / metabolism; Sequence Analysis, RNA; Streptococcus thermophilus / genetics; Streptococcus thermophilus / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

A Snapshot into the Metabolism of Isomalto-oligosaccharides in Probiotic Bacteria

Journal of Applied Glycoscience, 60(2), 95–100.

By: M. Hachem*, M. Møller*, J. Andersen*, F. Fredslund*, A. Majumder*, H. Nakai*, L. Leggio*, Y. Goh n ...

co-author countries: Denmark 🇩🇰 United States of America 🇺🇸
Source: ORCID
Added: January 2, 2020

2013 journal article

Antibiotic Resistance in Salmonella enterica Serovar Typhimurium Associates with CRISPR Sequence Type

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 57(9), 4282–4289.

By: M. DiMarzio*, N. Shariat*, S. Kariyawasam*, R. Barrangou n & E. Dudley*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Bifidobacterium animalis subsp lactis ATCC 27673 Is a Genomically Unique Strain within Its Conserved Subspecies

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 79(22), 6903–6910.

By: J. Loquasto*, R. Barrangou n, E. Dudley*, B. Stahl*, C. Chen* & R. Roberts*

co-author countries: United States of America 🇺🇸
MeSH headings : Base Composition; Bifidobacterium / classification; Bifidobacterium / genetics; Bifidobacterium / isolation & purification; Clustered Regularly Interspaced Short Palindromic Repeats; Comparative Genomic Hybridization; DNA, Bacterial / genetics; Genome, Bacterial; Genomic Islands; Molecular Sequence Data; Open Reading Frames; Sequence Analysis, DNA
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 book

CRISPR-Cas Systems

Rodolphe Barrangou

Ed(s): R. Barrangou* & J. Oost*

Source: ORCID
Added: January 2, 2020

2013 book

CRISPR-Cas Systems

Rodolphe Barrangou

Ed(s): R. Barrangou & J. Oost

Source: ORCID
Added: January 2, 2020

2013 review

CRISPR-Cas systems and RNA-guided interference

[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-RNA, 4(3), 267–278.

By: R. Barrangou n

co-author countries: United States of America 🇺🇸
MeSH headings : Archaea / genetics; Archaea / virology; Bacteria / genetics; Bacteria / virology; Gene Transfer, Horizontal; Interspersed Repetitive Sequences; Plasmids; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; RNA, Untranslated / genetics; RNA, Untranslated / metabolism; Recombination, Genetic; Repetitive Sequences, Nucleic Acid; Viruses / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

CRISPR-MVLST subtyping of Salmonella enterica subsp. enterica serovars Typhimurium and Heidelberg and application in identifying outbreak isolates

BMC Microbiology, 13(1), 254.

By: N. Shariat*, C. Sandt*, M. DiMarzio*, R. Barrangou n & E. Dudley*

co-author countries: United States of America 🇺🇸
author keywords: CRISPR subtyping; CRISPR-MVLST; Molecular subtyping; Salmonella Heidelberg; Salmonella Typhimurium
MeSH headings : DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Disease Outbreaks; Electrophoresis, Gel, Pulsed-Field; Foodborne Diseases / epidemiology; Foodborne Diseases / microbiology; Humans; Molecular Sequence Data; Molecular Typing / methods; Salmonella Infections / epidemiology; Salmonella Infections / microbiology; Salmonella enterica / classification; Salmonella enterica / genetics; Salmonella enterica / isolation & purification; Sequence Analysis, DNA; United States
Source: ORCID
Added: January 2, 2020

2013 journal article

Complete Genome Sequence of Probiotic Strain Lactobacillus acidophilus La-14

Genome Announcements, 1(3), e00376–13-e00376–13.

By: B. Stahl* & R. Barrangou n

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 2, 2020

2013 journal article

Genomic impact of CRISPR immunization against bacteriophages

BIOCHEMICAL SOCIETY TRANSACTIONS, 41(6), 1383–1391.

By: R. Barrangou n, A. Coute-Monvoisin*, B. Stahl*, I. Chavichvily*, F. Damange*, D. Romero*, P. Boyaval*, C. Fremaux*, P. Horvath*

co-author countries: France 🇫🇷 United States of America 🇺🇸
author keywords: adaptation; bacteriophage; clustered regularly interspaced short palindromic repeats; (CRISPR)-CRISPR-associated (Cas) system; draft genome; evolution
MeSH headings : Bacteriophages / immunology; Base Sequence; CRISPR-Cas Systems / genetics; CRISPR-Cas Systems / immunology; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / immunology; Genome, Bacterial / genetics; Molecular Sequence Data; Mutation / genetics; Streptococcus thermophilus / genetics; Streptococcus thermophilus / immunology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus

The EMBO Journal, 32(3), 385–394.

By: T. Sinkunas*, G. Gasiunas*, S. Waghmare*, M. Dickman*, R. Barrangou*, P. Horvath*, V. Siksnys*

co-author countries: France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Lithuania 🇱🇹 United States of America 🇺🇸
author keywords: DNA interference; DNA-dependent ATPase; nuclease
MeSH headings : Adaptive Immunity / immunology; Adenosine Triphosphate / metabolism; Base Sequence; Chromatography, High Pressure Liquid; Cloning, Molecular; DNA Cleavage; DNA Helicases / metabolism; Denaturing Gradient Gel Electrophoresis; Electrophoretic Mobility Shift Assay; In Vitro Techniques; Mass Spectrometry; Molecular Sequence Data; Plasmids / metabolism; RNA, Bacterial / genetics; RNA, Bacterial / immunology; Repetitive Sequences, Nucleic Acid / genetics; Repetitive Sequences, Nucleic Acid / immunology; Ribonucleoproteins / immunology; Ribonucleoproteins / metabolism; Rosaniline Dyes; Sequence Analysis, DNA; Streptococcus thermophilus / enzymology; Streptococcus thermophilus / immunology; Streptococcus thermophilus / virology
Source: ORCID
Added: January 2, 2020

2013 journal article

Phylogenetic Diversity of the Enteric Pathogen Salmonella enterica subsp enterica Inferred from Genome-Wide Reference-Free SNP Characters

GENOME BIOLOGY AND EVOLUTION, 5(11), 2109–2123.

By: R. Timme*, J. Pettengill*, M. Allard*, E. Strain*, R. Barrangou n, C. Wehnes*, J. Van Kessel*, J. Karns*, S. Musser*, E. Brown*

co-author countries: United States of America 🇺🇸
author keywords: H antigens; serovar; O antigens; CRISPR; lineage-through-time plot; comparative method
MeSH headings : Base Sequence; Clustered Regularly Interspaced Short Palindromic Repeats; Evolution, Molecular; Gene Transfer, Horizontal; Genome, Bacterial; Molecular Sequence Data; O Antigens / genetics; Phylogeny; Polymorphism, Single Nucleotide; Salmonella enterica / classification; Salmonella enterica / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

RNA-guided genome editing à la carte

Cell Research, 23(6), 733–734.

By: P. Horvath* & R. Barrangou n

co-author countries: France 🇫🇷 United States of America 🇺🇸
MeSH headings : CRISPR-Cas Systems / genetics; Clustered Regularly Interspaced Short Palindromic Repeats / genetics; DNA Restriction Enzymes; Endonucleases; Genetic Engineering; Humans; Plasmids / genetics; RNA / genetics; RNA / metabolism; RNA Editing / genetics; RNA, Guide, Kinetoplastida / genetics; RNA, Small Interfering / genetics; Viruses / genetics
Source: ORCID
Added: January 2, 2020

2013 review

Recent insight into oligosaccharide uptake and metabolism in probiotic bacteria

[Review of ]. BIOCATALYSIS AND BIOTRANSFORMATION, 31(4), 226–235.

By: M. Abou Hachem*, J. Andersen*, R. Barrangou n, M. Moller*, F. Fredslund*, A. Majumder*, M. Ejby*, S. Lahtinen* ...

co-author countries: Denmark 🇩🇰 Finland 🇫🇮 United States of America 🇺🇸
author keywords: Prebiotic; oligosaccharide uptake; ATP-binding cassette transport system; phosphotransferase system; transcriptional analysis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Strong bias in the bacterial CRISPR elements that confer immunity to phage

Nature Communications, 4, 1430.

By: D. Paez-Espino*, W. Morovic*, C. Sun*, B. Thomas*, K. Ueda*, B. Stahl*, R. Barrangou*, J. Banfield*

co-author countries: United States of America 🇺🇸
MeSH headings : Autoimmunity / genetics; Bacteriophages / physiology; Biological Evolution; DNA, Intergenic / genetics; Genetic Loci / genetics; Genome, Viral / genetics; High-Throughput Nucleotide Sequencing; Host-Pathogen Interactions / genetics; Immunity / genetics; Inverted Repeat Sequences / genetics; Open Reading Frames / genetics; Polymorphism, Single Nucleotide / genetics; Streptococcus thermophilus / genetics; Streptococcus thermophilus / immunology; Streptococcus thermophilus / virology
Source: ORCID
Added: January 2, 2020

2013 journal article

Subtyping of Salmonella enterica Serovar Newport Outbreak Isolates by CRISPR-MVLST and Determination of the Relationship between CRISPR-MVLST and PFGE Results

JOURNAL OF CLINICAL MICROBIOLOGY, 51(7), 2328–2336.

By: N. Shariat*, M. Kirchner*, C. Sandt*, E. Trees*, R. Barrangou n & E. Dudley*

co-author countries: United States of America 🇺🇸
MeSH headings : Cluster Analysis; DNA Fingerprinting / methods; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Electrophoresis, Gel, Pulsed-Field / methods; Genotype; Humans; Molecular Epidemiology / methods; Molecular Sequence Data; Multilocus Sequence Typing / methods; Salmonella enterica / classification; Salmonella enterica / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

The Evolutionary Divergence of Shiga Toxin-Producing Escherichia coli Is Reflected in Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) Spacer Composition

Applied and Environmental Microbiology, 79(18), 5710–5720.

By: S. Yin*, M. Jensen*, J. Bai*, C. DebRoy*, R. Barrangou n & E. Dudley*

co-author countries: United States of America 🇺🇸
MeSH headings : Cluster Analysis; Clustered Regularly Interspaced Short Palindromic Repeats; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Evolution, Molecular; False Negative Reactions; False Positive Reactions; Genetic Variation; Molecular Sequence Data; Real-Time Polymerase Chain Reaction / methods; Sensitivity and Specificity; Sequence Analysis, DNA; Shiga-Toxigenic Escherichia coli / classification; Shiga-Toxigenic Escherichia coli / genetics; United States
Source: ORCID
Added: January 2, 2020

2013 journal article

The Population and Evolutionary Dynamics of Phage and Bacteria with CRISPR–Mediated Immunity

PLoS Genetics, 9(3), e1003312.

By: B. Levin*, S. Moineau*, M. Bushman* & R. Barrangou*

co-author countries: Canada 🇨🇦 United States of America 🇺🇸

Ed(s): D. Hughes

MeSH headings : Bacteriophages / genetics; Bacteriophages / immunology; Base Sequence; Biological Evolution; DNA, Intergenic / genetics; Genetics, Population; Immunity / genetics; Interspersed Repetitive Sequences / genetics; Models, Theoretical; Molecular Sequence Data; Mutation; Sequence Analysis, DNA; Streptococcus thermophilus / genetics; Streptococcus thermophilus / immunology; Streptococcus thermophilus / virology
Source: ORCID
Added: January 2, 2020

2013 journal article

The combination of CRISPR-MVLST and PFGE provides increased discriminatory power for differentiating human clinical isolates of Salmonella enterica subsp. enterica serovar Enteritidis

Food Microbiology, 34(1), 164–173.

By: N. Shariat*, M. DiMarzio*, S. Yin*, L. Dettinger*, C. Sandt*, J. Lute*, R. Barrangou*, E. Dudley*

co-author countries: United States of America 🇺🇸
author keywords: Salmonella Enteritidis; CRISPR-MVLST; Molecular subtyping
MeSH headings : Bacterial Typing Techniques / methods; Electrophoresis, Gel, Pulsed-Field / methods; Feces / microbiology; Humans; Inverted Repeat Sequences; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction / methods; Salmonella Infections / microbiology; Salmonella enteritidis / classification; Salmonella enteritidis / genetics; Salmonella enteritidis / isolation & purification; Urine / microbiology
Source: ORCID
Added: January 2, 2020

2013 journal article

Transcriptional analysis of oligosaccharide utilization by Bifidobacterium lactis Bl-04

BMC GENOMICS, 14(1).

By: J. Andersen n, R. Barrangou*, M. Abou Hachem*, S. Lahtinen*, Y. Goh n, B. Svensson*, T. Klaenhammer n

co-author countries: Denmark 🇩🇰 Finland 🇫🇮 United States of America 🇺🇸
author keywords: Bifidobacterium lactis; Transcriptomics; ABC transporter; GPH transporter; Prebiotics; Glycoside hydrolase
MeSH headings : Bifidobacterium / drug effects; Bifidobacterium / genetics; Cell Membrane / drug effects; Cell Membrane / metabolism; Data Mining; Gene Expression Profiling; Genetic Variation / genetics; Genomics; Multigene Family / genetics; Oligosaccharides / pharmacology; Prebiotics; Transcription, Genetic / drug effects; Up-Regulation / drug effects
Sources: ORCID, Web Of Science
Added: August 6, 2018

2013 journal article

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus

RNA BIOLOGY, 10(5), 841–851.

By: T. Karvelis*, G. Gasiunas*, A. Miksys*, R. Barrangou n, P. Horvath* & V. Siksnys*

co-author countries: Belgium 🇧🇪 Czechia 🇨🇿 Lithuania 🇱🇹 United States of America 🇺🇸
author keywords: CRISPR; DNA silencing; Type II CRISPR-Cas systems
MeSH headings : Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; CRISPR-Associated Proteins / chemistry; CRISPR-Associated Proteins / genetics; CRISPR-Associated Proteins / metabolism; Clustered Regularly Interspaced Short Palindromic Repeats; DNA / genetics; Escherichia coli / genetics; Escherichia coli / metabolism; Molecular Sequence Data; RNA, Bacterial / chemistry; RNA, Bacterial / genetics; RNA, Bacterial / metabolism; Ribonuclease III / chemistry; Ribonuclease III / genetics; Ribonuclease III / metabolism; Sequence Alignment; Streptococcus pyogenes / genetics; Streptococcus pyogenes / metabolism; Streptococcus thermophilus / genetics; Streptococcus thermophilus / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Analysis of the Lactobacillus casei supragenome and its influence in species evolution and lifestyle adaptation

BMC Genomics, 13(1), 533.

By: J. Broadbent*, E. Neeno-Eckwall, B. Stahl*, K. Tandee*, H. Cai*, W. Morovic*, P. Horvath*, J. Heidenreich* ...

co-author countries: France 🇫🇷 United States of America 🇺🇸
author keywords: Lactobacillus casei; Lactic acid bacteria; Comparative genomics; Pan-genome; Supragenome; Evolution; Adaptation
MeSH headings : Adaptation, Physiological / genetics; Biological Evolution; Cluster Analysis; Gene Transfer, Horizontal; Genome, Bacterial; Genomic Islands; Lacticaseibacillus casei / genetics; Phylogeny
Source: ORCID
Added: January 2, 2020

2012 article

Applications of the Versatile CRISPR-Cas Systems

CRISPR-Cas Systems, pp. 267–286.

By: P. Horvath, G. Gasiunas, V. Siksnys & R. Barrangou*

Source: ORCID
Added: January 2, 2020

2012 article

Applications of the Versatile CRISPR-Cas Systems

CRISPR-Cas Systems, pp. 267–286.

By: P. Horvath*, G. Gasiunas*, V. Siksnys* & R. Barrangou*

co-author countries: France 🇫🇷 Lithuania 🇱🇹 United States of America 🇺🇸
Source: ORCID
Added: January 2, 2020

2012 journal article

CRISPR: New Horizons in Phage Resistance and Strain Identification

Annual Review of Food Science and Technology, 3(1), 143–162.

By: R. Barrangou* & P. Horvath

author keywords: bacteriophage; cas gene; interference; typing; immunity; starter culture
MeSH headings : Bacteriophages / classification; Bacteriophages / genetics; Bacteriophages / physiology; Fermentation; Food Microbiology / trends; Genes, Viral; Gram-Positive Bacteria / classification; Gram-Positive Bacteria / genetics; Gram-Positive Bacteria / metabolism; Gram-Positive Bacteria / virology; Inverted Repeat Sequences; Lysogeny; RNA Interference; RNA, Small Interfering
Source: ORCID
Added: January 2, 2020

2012 journal article

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

Proceedings of the National Academy of Sciences, 109(39), E2579–E2586.

By: G. Gasiunas*, R. Barrangou*, P. Horvath* & V. Siksnys*

co-author countries: France 🇫🇷 Lithuania 🇱🇹 United States of America 🇺🇸
author keywords: nuclease; site-directed mutagenesis; RNA interference; DNA interference
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; DNA Breaks, Double-Stranded; DNA Breaks, Single-Stranded; Endonucleases / genetics; Endonucleases / metabolism; RNA, Bacterial / genetics; RNA, Bacterial / metabolism; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism; Streptococcus thermophilus / enzymology; Streptococcus thermophilus / genetics
Source: ORCID
Added: January 2, 2020

2012 journal article

Complete Genome Sequences of Probiotic Strains Bifidobacterium animalis subsp. lactis B420 and Bi-07

Journal of Bacteriology, 194(15), 4131–4132.

By: B. Stahl* & R. Barrangou*

co-author countries: United States of America 🇺🇸
MeSH headings : Bifidobacterium / genetics; Bifidobacterium / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Genome, Bacterial; INDEL Mutation; Molecular Sequence Data; Polymorphism, Single Nucleotide; Probiotics; Repetitive Sequences, Nucleic Acid; Sequence Analysis, DNA
Source: ORCID
Added: January 2, 2020

2012 journal article

Persisting Viral Sequences Shape Microbial CRISPR-based Immunity

PLoS Computational Biology, 8(4), e1002475.

By: A. Weinberger*, C. Sun*, M. Pluciński*, V. Denef*, B. Thomas*, P. Horvath*, R. Barrangou*, M. Gilmore*, W. Getz*, J. Banfield*

co-author countries: France 🇫🇷 United States of America 🇺🇸

Ed(s): C. Mering