Rory B Conolly
Works (2)
Updated: July 19th, 2023 21:17
2011 journal article
Mechanistic Computational Model of Steroidogenesis in H295R Cells: Role of Oxysterols and Cell Proliferation to Improve Predictability of Biochemical Response to Endocrine Active Chemical-Metyrapone
TOXICOLOGICAL SCIENCES, 123(1), 80–93.
co-author countries:
United States of America 🇺🇸
author keywords: endocrine disrupting chemicals; mechanistic computational model; in vitro toxicology; metyrapone; H295R cells; steroid biosynthesis
MeSH headings : Adrenocortical Carcinoma / drug therapy; Adrenocortical Carcinoma / metabolism; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Cholesterol / analogs & derivatives; Cholesterol / metabolism; Computational Biology / methods; Endocrine Disruptors / toxicity; Enzyme Inhibitors / toxicity; Humans; Metyrapone / toxicity; Models, Theoretical; Predictive Value of Tests; Steroids / metabolism
academic.oup.com (publisher PDF)
Source: Web Of Science
Added: August 6, 2018
2007 article
Mechanistic computational model of ovarian steroidogenesis to predict biochemical responses to endocrine active compounds
Breen, M. S., Villeneuve, D. L., Breen, M., Ankley, G. T., & Conolly, R. B. (2007, June). ANNALS OF BIOMEDICAL ENGINEERING, Vol. 35, pp. 970–981.
co-author countries:
United States of America 🇺🇸
author keywords: steroid biosynthesis; mathematical model; sensitivity analysis; endocrine disrupting chemicals; fadrozole; fish; cellular metabolism
MeSH headings : Animals; Computer Simulation; Endocrine Disruptors / administration & dosage; Estradiol / biosynthesis; Female; Fishes / physiology; Gonadal Steroid Hormones / biosynthesis; Models, Biological; Ovary / drug effects; Ovary / metabolism; Signal Transduction / drug effects; Signal Transduction / physiology; Testosterone / biosynthesis
Source: Web Of Science
Added: August 6, 2018
