2009 journal article

Assessment of clotrimazole gels for in vitro stability and in vivo retention in the frontal sinus of dogs


By: K. Mathews n, K. Linder n, G. Davidson n, R. Goldman n & M. Papich n

MeSH headings : Animals; Antifungal Agents / chemistry; Antifungal Agents / metabolism; Antifungal Agents / pharmacokinetics; Clotrimazole / chemistry; Clotrimazole / metabolism; Clotrimazole / pharmacokinetics; Dogs / metabolism; Drug Stability; Frontal Sinus / diagnostic imaging; Frontal Sinus / metabolism; Gels / chemistry; Gels / metabolism; Male; Poloxamer / chemistry; Poloxamer / metabolism; Tomography, X-Ray Computed / veterinary
TL;DR: Poloxamer gels had the most promise for improving drug contact within the frontal sinus of dogs, while limiting the inflammatory response. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Vehicle effects on in vitro transdermal absorption of sevoflurane in the bullfrog, Rana catesbeiana


By: A. Ardente n, B. Barlow n, P. Burns*, R. Goldman n & R. Baynes n

author keywords: amphibian; dermal; sevofluame; in vitro; permeability
TL;DR: The flux-time profiles suggest that sevoflurane diffusion in bullfrog skin may be positively influenced by PLO, and future in vivo studies are required to assess sev ofLurane retention after removal of these formulations to more accurately control the plane of anesthesia in amphibians. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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