Works (21)

Updated: April 11th, 2023 10:13

2021 journal article

Binding specificity and function of the SWI/SNF subunit SMARCA4 bromodomain interaction with acetylated histone

JOURNAL OF BIOLOGICAL CHEMISTRY, 297(4).

By: P. Enriquez, K. Krajewski*, B. Strahl*, S. Rothbart*, R. Dowen* & R. Rose

Sources: ORCID, Web Of Science
Added: August 31, 2021

2021 journal article

Structure, Function, and Thermal Adaptation of the Biotin Carboxylase Domain Dimer from Hydrogenobacter thermophilus 2-Oxoglutarate Carboxylase

BIOCHEMISTRY, 60(4), 324–345.

By: G. Buhrman, P. Enriquez, L. Dillard n, H. Baer, V. Truong n, A. Grunden, R. Rose

Sources: ORCID, Web Of Science
Added: January 20, 2021

2016 journal article

5-Hydroxymethylcytosine in E-box motifs ACAT|GTG and ACAC|GTG increases DNA-binding of the B-HLH transcription factor TCF4

INTEGRATIVE BIOLOGY, 8(9), 936–945.

By: S. Khund-Sayeed*, X. He*, T. Holzberg*, J. Wang*, D. Rajagopal*, S. Upadhyay*, S. Durell*, S. Mukherjee* ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

A High-Resolution Crystal Structure of a Psychrohalophilic alpha-Carbonic Anhydrase from Photobacterium profundum Reveals a Unique Dimer Interface

PLOS ONE, 11(12).

By: V. Somalinga, G. Buhrman n, A. Arun n, R. Rose & A. Grunden

Ed(s): A. Hofmann

Sources: ORCID, Web Of Science
Added: August 6, 2018

2016 journal article

Modeling the Growth of Archaeon Halobacterium halobium Affected by Temperature and Light

Applied Biochemistry and Biotechnology, 181(3), 1080–1095.

By: H. Lu, W. Yuan, J. Cheng, R. Rose, J. Classen & O. Simmons n

author keywords: Halobacterium holobium; Sigmoidal model; Temperature effect; Light intensity effect; Bacteriorhodopsin
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Evaluation of a DLA-79 allele associated with multiple immune-mediated diseases in dogs

Immunogenetics, 68(3), 205–217.

By: S. Friedenberg, G. Buhrman, L. Chdid, N. Olby, T. Olivry, J. Guillaumin*, T. O’Toole*, R. Goggs* ...

author keywords: Canine; Immune-mediated disease; Dog leukocyte antigen; Major histocompatibility complex class Ib
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2015 journal article

Interactions with the Bifunctional Interface of the Transcriptional Coactivator DCoH1 Are Kinetically Regulated

JOURNAL OF BIOLOGICAL CHEMISTRY, 290(7), 4319–4329.

By: D. Wang n, M. Coco & R. Rose

Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Carboxylation of cytosine (5caC) in the CG dinucleotide in the E-box motif (CGCAG vertical bar GTG) increases binding of the Tcf3 vertical bar Ascl1 helix-loop-helix heterodimer 10-fold

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 449(2), 248–255.

By: J. Golla, J. Zhao, I. Mann, S. Sayeed, A. Mandal, R. Rose, C. Vinson

author keywords: Carboxylation; E-Box motif; CG dinucleotide; Basic-helix-loop-helix; DNA binding; Tcf3 vertical bar Ascl1 heterodimer
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Binding Polymorphism in the DNA Bound State of the Pdx1 Homeodomain

PLOS COMPUTATIONAL BIOLOGY, 9(8).

By: V. Babin, D. Wang n, R. Rose & C. Sagui

Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

A Novel DNA Binding Mechanism for maf Basic Region-Leucine Zipper Factors Inferred from a MafA-DNA Complex Structure and Binding Specificities

BIOCHEMISTRY, 51(48), 9706–9717.

By: X. Lu, G. Guanga*, C. Wan* & R. Rose

Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Crystallization and preliminary X-ray diffraction analysis of red clover necrotic mosaic virus

ACTA CRYSTALLOGRAPHICA SECTION F-STRUCTURAL BIOLOGY COMMUNICATIONS, 66(Pt 11), 1458–1462.

By: S. Martin, R. Guenther n, T. Sit, P. Swartz, F. Meilleur, S. Lommel, R. Rose, F. Section

author keywords: red clover necrotic mosaic virus; dianthoviruses; viruses
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Kinetic Stability May Determine the Interaction Dynamics of the Bifunctional Protein DCoH1, the Dimerization Cofactor of the Transcription Factor HNF-1 alpha

BIOCHEMISTRY, 49(47), 10187–10197.

By: H. Rho, C. Jones & R. Rose

Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

X-ray structure of the metcyano form of dehaloperoxidase from Amphitrite ornata: Evidence for photoreductive dissociation of the iron-cyanide bond

Acta Crystallographica. Section D, Biological Crystallography, 66, 770–782.

By: V. Serrano, M. Davis, J. Gaff, Q. Zhang, Z. Chen, E. D'Antonio, E. Bowden, R. Rose, S. Franzen

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

Crystal structure of E47 neuroD1/Beta2 bHLH domain DNA complex: Heterodimer selectivity and DNA recognition

BIOCHEMISTRY, 47(1), 218–229.

By: A. Longo n, G. Guanga & R. Rose

Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

Structural Basis for Induced Fit Mechanisms in DNA Recognition by the Pdx1 Homeodomain†,‡

Biochemistry, 46(11), 2948–2957.

By: A. Longo n, G. Guanga n & R. Rose

Sources: Crossref, ORCID
Added: February 10, 2020

2007 journal article

Structural basis for induced fit mechanisms in DNA recognition by the Pdx1 homeodomain

Biochemistry, 46(11), 2948–2957.

By: A. Longo, G. Guanga & R. Rose

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Structure of the conserved transcriptional repressor enhancer of rudimentary homolog

BIOCHEMISTRY, 44(13), 5017–5023.

By: C. Wan, W. Tempel n, Z. Liu n, B. Wang n & R. Rose

Sources: Web Of Science, ORCID
Added: August 6, 2018

2004 journal article

Biochemical and structural basis for partially redundant enzymatic and ranscriptional functions of DCoH and DCoH2

BIOCHEMISTRY, 43(23), 7345–7355.

By: R. Rose, K. Pullen*, J. Bayle*, G. Crabtree* & T. Alber*

Sources: Web Of Science, ORCID
Added: August 6, 2018

1998 journal article

Domain flexibility in retroviral proteases: structural implications for drug resistant mutations.

Biochemistry.

By: R. Rose, C. Craik* & R. Stroud*

Source: ORCID
Added: February 10, 2023

1996 journal article

Three-dimensional structures of HIV-1 and SIV protease product complexes.

Biochemistry.

By: R. Rose, C. Craik*, N. Douglas* & R. Stroud*

Source: ORCID
Added: February 10, 2023

1993 journal article

Structure of the protease from simian immunodeficiency virus: complex with an irreversible nonpeptide inhibitor.

Biochemistry.

By: R. Rose, R. Salto, C. Craik & R. Stroud

Source: ORCID
Added: February 10, 2023

Employment

Updated: December 13th, 2018 21:45

2002 - present

North Carolina State University Raleigh, NC, US
Associate Professor Biochemistry

Education

Updated: January 7th, 2019 11:14

1989 - 1996

UCSF Medical Center San Francisco, CA, US
PhD Biophysics

1977 - 1982

Yale University New Haven, CT, US
BA physics