2023 article

Linear and nonlinear rheology of liberase-treated breast cancer tumors

Corder, R. D., Vachieri, R. B., Martin, M. E., Taylor, D. K., Fleming, J. M., & Khan, S. A. (2023, January 31). BIOMATERIALS SCIENCE, Vol. 1.

By: R. Corder n, R. Vachieri*, M. Martin*, D. Taylor*, J. Fleming* & S. Khan n

MeSH headings : Mice; Animals; Thermolysin / metabolism; Mechanotransduction, Cellular; Collagenases / metabolism; Rheology; Neoplasms
TL;DR: Examination of the Lissajous-Bowditch curves, Chebyshev coefficient ratios, elastic moduli, and dynamic viscosities demonstrate that the onset and type of nonlinear behavior is independent of treatment type and elastic modulus, suggesting that multiple liberase injections do not affect the nonlinear viscoelasticity of 4T1 tumors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: February 7, 2023

2021 journal article

Guar Gel Binders for Silicon Nanoparticle Anodes: Relating Binder Rheology to Electrode Performance


By: M. Dufficy n, R. Corder n, K. Dennis n, P. Fedkiw n & S. Khan n

author keywords: polymer binder; guar gel; carbon black; cross-linking; silicon anode; lithium-ion battery
TL;DR: The composite hydrogel with integrated conductive additives gives promise to a new type of binder for next-generation lithium-ion batteries that demonstrates the potential for self-healing, as evidenced by an increased elastic modulus after the gel was mechanically fragmented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: October 21, 2021

2021 journal article

Using rheology to quantify the effects of localized collagenase treatments on uterine fibroid digestion


By: R. Corder n, S. Gadi n, R. Vachieri*, F. Jayes*, J. Cullen n, S. Khan n, D. Taylor*

author keywords: Uterine fibroids; Collagenase; Drug delivery; Rheology; Histology
MeSH headings : Animals; Collagenases; Digestion; Female; Humans; Leiomyoma / drug therapy; Mice; Rheology; Treatment Outcome; Uterine Neoplasms
TL;DR: Rheological results from an in vivo digestion study in mice show a significant reduction in tissue modulus and increase in tissue viscoelasticity 7 days after a single injection of LQG+CCH, and show promise for development of injectable and localized enzymatic therapies for uterine fibroids and other dense tumors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: November 8, 2021

journal article

Core-Shell Microneedle Gel for Self-Regulated Insulin Delivery

Wang, J. Q., Ye, Y. Q., Yu, J. C., Kahkoska, A. R., Zhang, X. D., Wang, C., … Gu, Z. ACS Nano, 12(3), 2466–2473.

By: J. Wang, Y. Ye, J. Yu, A. Kahkoska, X. Zhang, C. Wang, W. Sun, R. Corder ...

Source: NC State University Libraries
Added: August 6, 2018

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