@article{nordberg_huebner_schuchard_mellor_shirwaiker_loboa_spang_2021, title={The evaluation of a multiphasic 3D-bioplotted scaffold seeded with adipose derived stem cells to repair osteochondral defects in a porcine model}, volume={6}, ISSN={["1552-4981"]}, DOI={10.1002/jbm.b.34886}, abstractNote={Abstract}, journal={JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS}, author={Nordberg, Rachel C. and Huebner, Pedro and Schuchard, Karl G. and Mellor, Liliana F. and Shirwaiker, Rohan A. and Loboa, Elizabeth G. and Spang, Jeffery T.}, year={2021}, month={Jun} }
 @article{mellor_nordberg_huebner_mohiti-asli_taylor_efird_oxford_spang_shirwaiker_loboa_2020, title={Investigation of multiphasic 3D-bioplotted scaffolds for site-specific chondrogenic and osteogenic differentiation of human adipose-derived stem cells for osteochondral tissue engineering applications}, volume={108}, ISSN={["1552-4981"]}, DOI={10.1002/jbm.b.34542}, abstractNote={Abstract}, number={5}, journal={JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS}, author={Mellor, Liliana F. and Nordberg, Rachel C. and Huebner, Pedro and Mohiti-Asli, Mahsa and Taylor, Michael A. and Efird, William and Oxford, Julia T. and Spang, Jeffrey T. and Shirwaiker, Rohan A. and Loboa, Elizabeth G.}, year={2020}, month={Jul}, pages={2017–2030} }
 @article{watson_nordberg_loboa_kullman_2019, title={Evidence for Aryl hydrocarbon Receptor-Mediated Inhibition of Osteoblast Differentiation in Human Mesenchymal Stem Cells}, volume={167}, ISSN={["1096-0929"]}, DOI={10.1093/toxsci/kfy225}, abstractNote={Multipotent mesenchymal stem cells (MSCs) maintain the ability to differentiate into adipogenic, chondrogenic, or osteogenic cell lineages. There is increasing concern that exposure to environmental agents such as aryl hydrocarbon receptor (AhR) ligands, may perturb the osteogenic pathways responsible for normal bone formation. The objective of the current study was to evaluate the potential of the prototypic AhR ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) to disrupt osteogenic differentiation of human bone-derived MSCs (hBMSCs) in vitro. Primary hBMSCs from three donors were exposed to 10 nM TCDD and differentiation was interrogated using select histological, biochemical, and transcriptional markers of osteogenesis. Exposure to 10 nM TCDD resulted in an overall consistent attenuation of alkaline phosphatase (ALP) activity and matrix mineralization at terminal stages of differentiation in primary hBMSCs. At the transcriptional level, the transcriptional regulator DLX5 and additional osteogenic markers (ALP, OPN, and IBSP) displayed attenuated expression; conversely, FGF9 and FGF18 were consistently upregulated in each donor. Expression of stem cell potency markers SOX2, NANOG, and SALL4 decreased in the osteogenic controls, whereas expression in TCDD-treated cells resembled that of undifferentiated cells. Coexposure with the AhR antagonist GNF351 blocked TCDD-mediated attenuation of matrix mineralization, and either fully or partially rescued expression of genes associated with osteogenic regulation, extracellular matrix, and/or maintenance of multipotency. Thus, experimental evidence from this study suggests that AhR transactivation likely attenuates osteoblast differentiation in multipotent hBMSCs. This study also underscores the use of primary human MSCs to evaluate osteoinductive or osteotoxic potential of chemical and pharmacologic agents in vitro.}, number={1}, journal={TOXICOLOGICAL SCIENCES}, author={Watson, AtLee T. D. and Nordberg, Rachel C. and Loboa, Elizabeth G. and Kullman, Seth W.}, year={2019}, month={Jan}, pages={145–156} }
 @article{mellor_steward_nordberg_taylor_loboa_2017, title={Comparison of simulated microgravity and hydrostatic pressure for chondrogenesis of hASC}, volume={88}, number={4}, journal={Aerospace Medicine and Human Performance}, author={Mellor, L. F. and Steward, A. J. and Nordberg, R. C. and Taylor, M. A. and Loboa, E. G.}, year={2017}, pages={377–384} }
 @article{nordberg_zhang_griffith_frank_starly_loboa_2017, title={Electrical Cell-Substrate Impedance Spectroscopy Can Monitor Age-Grouped Human Adipose Stem Cell Variability During Osteogenic Differentiation}, volume={6}, ISSN={["2157-6580"]}, DOI={10.5966/sctm.2015-0404}, abstractNote={Abstract}, number={2}, journal={STEM CELLS TRANSLATIONAL MEDICINE}, author={Nordberg, Rachel C. and Zhang, Jianlei and Griffith, Emily H. and Frank, Matthew W. and Starly, Binil and Loboa, Elizabeth G.}, year={2017}, month={Feb}, pages={502–511} }
 @article{nordberg_charoenpanich_vaughn_griffith_fisher_cole_spang_loboa_2016, title={Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method}, volume={11}, journal={Journal of Orthopaedic Surgery and Research}, author={Nordberg, R. C. and Charoenpanich, A. and Vaughn, C. E. and Griffith, E. H. and Fisher, M. B. and Cole, J. H. and Spang, J. T. and Loboa, E. G.}, year={2016} }
 @article{nordberg_loboa_2015, title={Our Fat Future: Translating Adipose Stem Cell Therapy}, volume={4}, ISSN={["2157-6580"]}, DOI={10.5966/sctm.2015-0071}, abstractNote={Abstract}, number={9}, journal={STEM CELLS TRANSLATIONAL MEDICINE}, author={Nordberg, Rachel C. and Loboa, Elizabeth G.}, year={2015}, month={Sep}, pages={974–979} }