Works (91)

2021 journal article

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

NUCLEIC ACIDS RESEARCH, 12.

By: P. Kaur, R. Barnes, H. Pan, A. Detwiler, M. Liu, C. Mahn, J. Hall, Z. Messenger ...

Sources: Web Of Science, ORCID
Added: January 18, 2022

2020 journal article

Measurement of Novel, Drinking Water-Associated PFAS in Blood from Adults and Children in Wilmington, North Carolina

ENVIRONMENTAL HEALTH PERSPECTIVES, 128(7).

By: N. Kotlarz, J. McCord, D. Collier, C. Lea, M. Strynar, A. Lindstrom, A. Wilkie, J. Islam ...

Sources: Web Of Science, ORCID
Added: August 24, 2020

2019 journal article

C/EBP beta suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer

CARCINOGENESIS, 40(9), 1099–1109.

Sources: Web Of Science, ORCID
Added: November 18, 2019

2018 journal article

C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event

Cell Death & Disease, 9(11).

By: Z. Messenger, J. Hall, D. Jima, J. House, H. Tam, D. Tokarz, R. Smart

Sources: Crossref, ORCID
Added: February 21, 2020

2018 chapter

Carcinogenesis

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.

By: R. Smart & J. Hall

Ed(s): R. Smart & E. Hodgson

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2018 chapter

Molecular Techniques in the Study of Gene Function

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.

By: Y. Tsuji & R. Smart

Ed(s): R. Smart & E. Hodgson

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2018 book

Molecular and Biochemical Toxicology

(5th ed.). Hoboken, NJ: J. Wiley and Sons.

Ed(s): R. Smart & E. Hodgson

Source: NC State University Libraries
Added: May 8, 2022

2018 book

Molecular and Biochemical Toxicology

(5th ed.). J. Wiley and Sons.

By: R. Smart

Source: ORCID
Added: May 12, 2022

2018 chapter

Molecular and Biochemical Toxicology: Definition and Scope

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (5th ed.). Hoboken, NJ: J Wiley and Sons.

By: R. Smart & E. Hodgson

Ed(s): R. Smart & E. Hodgson

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2015 journal article

Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

Cell Death & Disease, 6.

By: J. Hall, Z. Messenger, H. Tam, S. Phillips, L. Recio & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

C/EBP alpha regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G(1)/S checkpoint

Cell Cycle, 13(22), 3602–3610.

By: J. Hall, M. Bereman, A. Nepomuceno, E. Thompson, D. Muddiman & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

C/EBP alpha expression Is downregulated in human nonmelanoma skin cancers and inactivation of C/EBP alpha confers susceptibility to UVB-induced skin squamous cell carcinomas

Journal of Investigative Dermatology, 131(6), 1339–1346.

By: E. Thompson, S. Zhu, J. Hall, J. House, R. Ranjan, J. Burr, Y. He, D. Owens, R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo

International Journal of Mass Spectrometry, 301(1-3), 12–21.

By: L. Deterding, J. Williams, M. Humble, R. Petrovich, S. Wei, C. Trempus, M. Gates, F. Zhu ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Control of skin cancer by the circadian rhythm

Proceedings of the National Academy of Sciences, 108(46), 18790–18795.

By: S. Gaddameedhi, C. Selby, W. Kaufmann, R. Smart & A. Sancar

Sources: Crossref, ORCID
Added: February 24, 2020

2011 journal article

PTEN positively regulates UVB-induced DNA damage repair

Cancer Research, 71(15), 5287–5295.

By: M. Ming, L. Feng, C. Shea, K. Soltani, B. Zhao, W. Han, R. Smart, C. Trempus, Y. He

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

Ablation of TAK1 Upregulates Reactive Oxygen Species and Selectively Kills Tumor Cells

Cancer Research, 70(21), 8417–8425.

By: E. Omori, K. Matsumoto, S. Zhu, R. Smart & J. Ninomiya-Tsuji

Sources: Crossref, ORCID
Added: April 9, 2022

2010 journal article

C/EBP alpha and C/EBP beta are required for sebocyte differentiation and stratified squamous differentiation in adult mouse skin

PLoS One, 5(3).

By: J. House, S. Zhu, R. Ranjan, K. Linder & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 chapter

Chemical Carcinogenesis and Mutagenesis

In E. Hodgson (Ed.), Modern Toxicology (4th ed.). New York: J. Wiley and Sons.

By: R. Smart

Ed(s): E. Hodgson

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2010 journal article

Overexpression of transcription factor Sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis

Cancer Research, 70(21), 8507–8516.

By: T. Kim, S. Chiera, K. Linder, C. Trempus, R. Smart & J. Horowitz

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2010 journal article

RSK-mediated phosphorylation in the C/EBP beta Leucine zipper regulates DNA binding, dimerization, and growth arrest activity

Molecular and Cellular Biology, 30(11), 2621–2635.

By: S. Lee, J. Shuman, T. Guszczynski, K. Sakchaisri, T. Sebastian, T. Copeland, M. Miller, M. Cohen ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2009 journal article

C/EBP alpha expression is partially regulated by C/EBP beta in response to DNA damage and C/EBP alpha-deficient fibroblasts display an impaired G(1) checkpoint

Oncogene, 28(36), 3235–3245.

By: R. Ranjan, E. Thompson, K. Yoon & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 journal article

C/EBP beta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf)

Cell Death and Differentiation, 15(11), 1734–1744.

By: S. Ewing, S. Zhu, F. Zhu, J. House & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2008 chapter

Carcinogenesis

In Molecular and Biochemical Toxicology (4th ed., pp. 537–586).

By: R. Smart, S. Ewing & K. Loomis

Sources: Crossref, ORCID
Added: April 9, 2022

2008 book

Molecular and Biochemical Toxicology

(R. C. Smart & E. Hodgson, Eds.).

By: N. Libraries

Ed(s): R. Smart & E. Hodgson

Sources: Crossref, ORCID
Added: April 10, 2022

2008 chapter

Molecular and Biochemical Toxicology: Definition and Scope

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 1–4).

By: E. Hodgson & R. Smart

Ed(s): R. Smart & E. Hodgson

Sources: Crossref, ORCID
Added: April 9, 2022

2008 chapter

Overview of Molecular Techniques in Toxicology: Genes and Transgenes

In R. C. Smart & E. Hodgson (Eds.), Molecular and Biochemical Toxicology (4th ed., pp. 5–24).

By: R. Smart

Ed(s): R. Smart & E. Hodgson

Sources: Crossref, ORCID
Added: April 9, 2022

2007 journal article

Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function

Oncogene, 26(3), 360–367.

By: K. Yoon, S. Zhu, S. Ewing & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2007 journal article

Genetic ablation of CCAAT/Enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis

Cancer Research, 67(14), 6768–6776.

By: K. Loomis, S. Zhu, K. Yoon, P. Johnson & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis

Oncogene, 25(8), 1272–1276.

By: E. Sterneck, S. Zhu, A. Ramirez, J. Jorcano & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

Journal of Biological Chemistry, 281(28), 19610–19617.

By: E. Omori, K. Matsumoto, H. Sanjo, S. Sato, S. Akira, R. Smart, J. Ninomiya-Tsuji

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2005 journal article

Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation

Cancer Research, 65(3), 861–867.

By: M. Shim, K. Powers, S. Ewing, S. Zhu & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

C/EBP alpha is a DNA damage-inducible p53-regulated mediator of the G(1) checkpoint in keratinocytes

Molecular and Cellular Biology, 24(24), 10650–10660.

By: K. Yoon & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Cell cycle-dependent phosphorylation of C/EBP beta mediates oncogenic cooperativity between C/EBP beta and H-Ras(V12)

Molecular and Cellular Biology, 24(17), 7380–7391.

By: J. Shuman, T. Sebastian, P. Kaldis, T. Copeland, S. Zhu, R. Smart, P. Johnson

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2004 chapter

Chemical Carcinogenesis

In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 225–250).

By: R. Smart

Ed(s): E. Hodgson

Sources: Crossref, ORCID
Added: April 9, 2022

2004 chapter

Introduction to Biochemical and Molecular Methods in Toxicology

In E. Hodgson (Ed.), A Textbook of Modern Toxicology (pp. 13–22).

By: E. Hodgson, G. Leblanc, S. Meyer & R. Smart

Ed(s): E. Hodgson

Sources: Crossref, ORCID
Added: April 10, 2022

2003 journal article

Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBP alpha) through a glycogen synthase kinase 3 (GSK3)- independent pathway involving direct inhibition of proteasomal activity

Journal of Biological Chemistry, 278(22), 19674–19681.

By: M. Shim & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2003 patent

Method of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

2003 article

Method of treating alopecia

(Vol. 6, 555, 532). Vol. 6, 555, 532. Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: ORCID
Added: May 12, 2022

2002 journal article

17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice

Toxicological Sciences, 69(1), 42–48.

By: K. Porter, S. Chanda, H. Wang, K. Gaido, R. Smart & C. Robinette

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

Proceedings of the National Academy of Sciences of the United States of America, 99(1), 207–212.

By: S. Zhu, K. Yoon, E. Sterneck, P. Johnson & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2002 journal article

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

Cancer Research, 62(12), 3395–3401.

By: H. Tiano, C. Loftin, J. Akunda, C. Lee, J. Spalding, A. Sessoms, D. Dunson, E. Rogan ...

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2001 chapter

Biochemical Toxicology: Definition and Scope

In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (pp. 1–10). New York: J. Wiley and Sons.

By: E. Hodgson & R. Smart

Ed(s): E. Hodgson & R. Smart

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2001 chapter

Carcinogenesis

In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (3rd ed., pp. 343–398). New York: J. Wiley and Sons.

By: R. Smart & J. Akunda

Ed(s): E. Hodgson & R. Smart

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2001 book

Introduction to Biochemical Toxicology

(3rd ed.). New York: J. Wiley and Sons.

Ed(s): E. Hodgson & R. Smart

Source: NC State University Libraries
Added: May 8, 2022

2001 book

Introduction to Biochemical Toxicology

(3rd ed.). J. Wiley and Sons.

By: R. Smart

Source: ORCID
Added: May 12, 2022

2001 patent

Method of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

2001 article

Method of treating alopecia

(Vol. 6, 204, 258). Vol. 6, 204, 258. Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: ORCID
Added: May 12, 2022

2001 chapter

Molecular Techniques in Toxicology

In E. Hodgson & R. C. Smart (Eds.), Introduction to Biochemical Toxicology (3rd ed., pp. 11–32). New York: J. Wiley and Sons.

By: R. Smart

Ed(s): E. Hodgson & R. Smart

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

2001 journal article

Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes

Molecular Pharmacology, 59(4), 860–866.

By: H. Wang, M. Kim, H. Tiano, R. Langenbach & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2000 journal article

17 beta-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway

American Journal of Physiology, 278(2), E202–210.

By: S. Chanda, C. Robinette, J. Couse & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

A multihit, multistage model of chemical carcinogenesis

Carcinogenesis, 20(9), 1837–1844.

By: D. Owens, S. Wei & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

C/EBP beta modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression

Molecular and Cellular Biology, 19(10), 7181–7190.

By: S. Zhu, H. Oh, M. Shim, E. Sterneck, P. Johnson & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Correlation between expression of peroxisome proliferator- activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells

Molecular and Cellular Endocrinology, 147(1-2), 85–92.

By: H. Matsuura, H. Adachi, R. Smart, X. Xu, J. Arata & A. Jetten

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice

Journal of Investigative Dermatology, 4(3), 285–289.

By: R. Smart, H. Oh, S. Chanda & C. Robinette

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1999 patent

Methods of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

1999 article

Methods of treating alopecia

(Vol. 5, 965, 551). Vol. 5, 965, 551. Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: ORCID
Added: May 12, 2022

1999 journal article

Overexpression of protein kinase C-[alpha] in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2, and TNF-[alpha] but not tumor promotion

Journal of Cell Science, 112(20), 3497–3506.

By: H. Wang & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1998 journal article

Expression of CCAAT/enhancer binding proteins (C/EBP) is associated with squamous differentiation in epidermis and isolated primary keratinocytes and is altered in neoplasms

Journal of Investigative Dermatology, 110(6), 939–945.

By: H. Oh & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1998 article

On the effect of estrogen receptor agonists and antagonists on the mouse hair follicle cycle

Journal of Investigative Dermatology, Vol. 111, p. 175.

By: R. Smart & H. Oh

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1997 journal article

Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha ras genotype

Molecular Carcinogenesis, 20(1), 115–124.

By: T. Kim, K. Porter, J. Foley, R. Maronpot & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1996 journal article

An estrogen receptor pathway regulates the telogen-anagen hair follicle transition and influences epidermal cell proliferation.

Proceedings of the National Academy of Sciences, 93(22), 12525–12530.

By: H. Oh & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1996 journal article

Epidermal Protein Kinase C-β2 Is Highly Sensitive to Downregulation and Is Exclusively Expressed in Langerhans Cells: Downregulation Is Associated with Attenuated Contact Hypersensitivity

Journal of Investigative Dermatology, 107(3), 354–359.

By: A. Goodell, H. Oh, S. Meyer & R. Smart

Sources: Crossref, ORCID
Added: April 9, 2022

1996 journal article

Localization and Expression of Cornifin-α/SPRR1 in Mouse Epidermis, Anagen Follicles, and Skin Neoplasms

Journal of Investigative Dermatology, 106(4), 647–654.

By: D. Owens, A. Jetten, R. Smart & T. Zainal

Sources: Crossref, ORCID
Added: April 10, 2022

1995 journal article

Genetic alterations cooperate with v-Ha-ras to accelerate multistage carcinogenesis in TG.AC transgenic mouse skin

Cancer Research, 55(14), 3171–3178.

By: D. Owens, J. Spalding, R. Tennant & R. Smart

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1995 journal article

Lack of effect of retinoic acid and fluocinolone acetonide on mirex tumor promotion indicates a novel mirex mechanism

Carcinogenesis, 16(9), 2199–2204.

By: T. Kim & R. Smart

Sources: Crossref, ORCID
Added: April 9, 2022

1994 journal article

Synergistic interaction between the non-phorbol ester type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion

Carcinogenesis, 15, 47–52.

By: S. Meyer, T. Kim, G. Moser, N. Monteiro-Riviere & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1993 chapter

Carcinogenesis

In E. Hodgson & P. E. Levi (Eds.), Biochemical Toxicology (2nd ed., pp. 381–414). Norwalk, CT: Appleton and Lange.

By: R. Smart

Ed(s): E. Hodgson & P. Levi

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1993 journal article

Characterization of benzo[a]pyrene-initiated mouse skin papillomas for Ha-ras mutations and protein kinase C levels

Carcinogenesis, 14(11), 2289–2295.

By: A. Colapietro, A. Goodell & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1993 journal article

Characterization of skin tumor promotion by mirex: structure-activity relationships, sexual dimorphism and presence of Ha-ras mutation

Carcinogenesis, 14(6), 1155–1160.

By: G. Moser, C. Robinette & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1993 journal article

Diacylglycerol is an effector of the clonal expansion of cells containing activated Ha-ras genes

Carcinogenesis, 14(12), 2645–2648.

By: K. Mills, S. Reynolds & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1993 journal article

Minimal role of enhanced cell proliferation in skin tumor promotion by mirex, a new nonphorbol ester-type promoter

Environmental Health Perspectives, 101(Suppl. 5), 265–270.

By: S. Meyer, G. Moser, N. Monteiro-Riviere & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1992 journal article

Alterations in protein kinase C isozymes α and β2 in activated Ha-ras containing papillomas in the absence of an increase in diacyiglycerol

Carcinogenesis, 13(7), 1113–1120.

By: K. Mills, S. Bocckino, D. Burns, C. Loomis & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1992 journal article

The chlorinated pesticide, mirex is a novel non-phorbol ester tumor promoter in mouse skin

Cancer Research, 52(3), 631–636.

By: G. Moser, S. Meyer & R. Smart

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1991 journal article

Effect of ascorbic acid and its synthetic lipophilic derivative ascorbyl palmitate on phorbol ester-induced skin-tumor promotion in mice

American Journal of Clinical Nutrition, 54, 1266.

By: R. Smart & C. Crawford

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1991 chapter

Pesticides, tumor promotion and risk assessment in Pesticides and the Future: Toxicological Studies of Risks and Benefits

In E. Hodgson, R. M. Roe, & N. Motoyama (Eds.), Reviews in Pesticides I (pp. 349–357).

By: R. Smart & G. Moser

Ed(s): E. Hodgson, R. Roe & N. Motoyama

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1990 journal article

Differential down-regulation of epidermal protein kinase C (PKC) by tetradecanoylphorbol-13-acetate and diacylglycerol: Association with epidermal hyperplasia and tumor promotion

Cancer Research, 50, 5740–5745.

By: L. Hansen, N. Monteiro-Riviere & R. Smart

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1989 journal article

Comparison of epidermal protein kinase C activity, ornithine decarboxylase induction and DNA synthesis stimulated by TPA or dioctanoylglycerol in mouse strains with differing susceptibility to TPA-induced tumor promotion

Carcinogenesis, 10(5), 833–838.

By: K. Mills & R. Smart

Sources: Crossref, ORCID
Added: April 9, 2022

1989 journal article

Hepatic tumor-promoting chlorinated hydrocarbons stimulate protein kinase C activity

Carcinogenesis, 10(5), 851–856.

By: G. Moser & R. Smart

Sources: Crossref, ORCID
Added: April 10, 2022

1989 journal article

Synthetic lipid second messenger, sn-1,2-didecanoylglycerol: A complete tumor promoter in mouse skin

Cancer Research, 49(16), 4455–4458.

By: R. Smart, K. Mills, L. Hansen & A. Conney

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1988 journal article

Comparison of the effect of sn-1,2-didecanoylglycerol and 12-o-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD 1 mice

Carcinogenesis, 9, 2221–2226.

By: R. Smart, M. Huang, N. Monteiro-Riviere, C. Wong, K. Mills & A. Conney

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1988 journal article

Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-o-tetradecanoylphorbol-13-acetate

Cancer Research, 48(21), 5941–5946.

By: M. Huang, R. Smart, C. Wong & A. Conney

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

1987 journal article

Ascorbic Acid, Alcohol, and Environmental Chemicals

Annals of the New York Academy of Sciences, 498(1 Third Confere), 364–388.

By: V. Zannoni, J. Brodfuehrer, R. Smart & R. Susick

Sources: Crossref, ORCID
Added: April 9, 2022

1987 journal article

Characterization of purified DT-diaphorase from liver cytosol of 3-methylcholanthrene-treated rats

Chemica Scripta, 27A:49-54.

By: M. Huang, R. Smart, P. Thomas, C. Pickett & Y. Lu

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1987 journal article

Inhibition of 12-O-Tetradecanoylphorbol-13-acetate Induction of Ornithine Decarboxylase Activity, DNA Synthesis, and Tumor Promotion in Mouse Skin by Ascorbic Acid and Ascorbyl Palmitate

Cancer Research, 47(24, Part 1), 6633–6638.

By: R. Smart, M. Huang, Z. Han, M. Kaplan, A. Focella & A. Conney

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1986 journal article

Disposition of the naturally occurring antimutagenic plant phenol, ellagic acid, and its synthetic derivatives, 3-O-decylellagic acid and 3, 3'-di-O-methylellagic acid in mice

Carcinogenesis, 7(10), 1663–1667.

By: R. Smart, M. Huang, R. Chang, J. Sayer, D. Jerina & A. Conney

Sources: Crossref, ORCID
Added: April 10, 2022

1986 journal article

Effect of dietary ascorbate on covalent binding of benzene to bone marrow and hepatic tissue in vivo

Biochemical Pharmacology, 35(18), 3180–3182.

By: R. Smart & V. Zannoni

Sources: Crossref, ORCID
Added: April 9, 2022

1986 journal article

Effect of ellagic acid and 3-O-decylellagic acid on the formation of benzo[a]pyrene-derived DNA adducts in vivo and on the tumorigenicity of 3-methylcholanthrene in mice

Carcinogenesis, 7(10), 1669–1675.

By: R. Smart, M. Huang, R. Chang, J. Sayer, D. Jerina, A. Wood, A. Conney

Sources: Crossref, ORCID
Added: April 10, 2022

1986 journal article

sn-l, 2-Diacylglycerols mimic the effects of 12-0-tetradecanoylphorbol-13-acetate in vivo by inducing biochemical changes associated with tumor promotion in mouse epidermis

Carcinogenesis, 7(11), 1865–1870.

By: R. Smart, M. Huang & A. Conney

Sources: Crossref, ORCID
Added: April 10, 2022

1985 journal article

Effect of ascorbate on covalent binding of benzene and phenol metabolites to isolated tissue preparations

Toxicology and Applied Pharmacology, 77(2), 334–343.

By: R. Smart & V. Zannoni

Sources: Crossref, ORCID
Added: April 9, 2022

1984 chapter

Ascorbic acid as it relates to the metabolism of drugs and environmental chemicals

In M. Wimick (Ed.), Nutrition in the 20th Century (pp. 21–36). New York: John Wiley and Sons.

By: V. Zannoni, R. Susick & R. Smart

Ed(s): M. Wimick

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

1984 journal article

DT-Diaphorase and peroxidase influence the covalent binding of the metabolites of phenol, the major metabolite of benzene

Molecular Pharmacology, 26(1), 105–111.

By: R. Smart & V. Zannoni

Sources: NC State University Libraries, ORCID
Added: May 5, 2022

Employment

1986 - present

North Carolina State University Raleigh, North Carolina, US
Professor; Goodnight Distinguished Chair in Molecular Toxicology Biological Sciences

Education

1980 - 1984

University of Michigan Ann Arbor, MI, US
PhD Toxicology

1974 - 1977

University of Massachusetts at Darmouth Darmouth, Massachusetts, US
BS Biology

Funding History

Funding history based on the linked ORCID record.

grant June 1, 2016 - May 31, 2022
Role of Long Intergenic Noncoding RNA in UVB-induced Apoptosis and Skin Cancer
National Institute of Environmental Health Sciences
grant April 20, 2015 - March 31, 2025
Center for Human Health and the Environment (CHHE)
National Institute of Environmental Health Sciences
grant January 3, 2005 - December 31, 2011
Regulation and Function of C/EBP in UVB Responses
National Institute of Environmental Health Sciences
grant August 1, 1996 - July 31, 2001
MECHANISM OF PESTICIDE MIREX INDUCED TUMOR PROMOTION
National Institute of Environmental Health Sciences
grant May 1, 1990 - May 31, 2015
Role of C/EBP in Cell Survival and Neoplasia
National Cancer Institute
grant May 1, 1990 - April 30, 1996
DIACYLGLYCEROLS AS TUMOR PROMOTERS
National Cancer Institute
grant November 23, 1988 - June 30, 2006
ENVIRONMENTAL HEALTH SCIENCES
National Institute of Environmental Health Sciences
grant April 1, 1979 - September 29, 1992
BIOMEDICAL RESEARCH SUPPORT
National Center for Advancing Translational Sciences
grant July 1, 1977 - June 30, 2026
Molecular Pathways to Pathogenesis in Toxicology
National Institute of Environmental Health Sciences
grant December 1, 1976 - February 28, 1997
MECHANISMS OF PESTICIDE TOXICOLOGY
National Institute of Environmental Health Sciences