Works (40)

2015 journal article

Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

Cell Death & Disease, 6.

By: J. Hall, Z. Messenger, H. Tam, S. Phillips, L. Recio & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

C/EBP alpha regulates CRL4(Cdt2)-mediated degradation of p21 in response to UVB-induced DNA damage to control the G(1)/S checkpoint

Cell Cycle, 13(22), 3602–3610.

By: J. Hall, M. Bereman, A. Nepomuceno, E. Thompson, D. Muddiman & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

C/EBP alpha expression Is downregulated in human nonmelanoma skin cancers and inactivation of C/EBP alpha confers susceptibility to UVB-induced skin squamous cell carcinomas

Journal of Investigative Dermatology, 131(6), 1339–1346.

By: E. Thompson, S. Zhu, J. Hall, J. House, R. Ranjan, J. Burr, Y. He, D. Owens, R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

CD34 antigen: Determination of specific sites of phosphorylation in vitro and in vivo

International Journal of Mass Spectrometry, 301(1-3), 12–21.

By: L. Deterding, J. Williams, M. Humble, R. Petrovich, S. Wei, C. Trempus, M. Gates, F. Zhu ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

PTEN positively regulates UVB-induced DNA damage repair

Cancer Research, 71(15), 5287–5295.

By: M. Ming, L. Feng, C. Shea, K. Soltani, B. Zhao, W. Han, R. Smart, C. Trempus, Y. He

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

C/EBP alpha and C/EBP beta are required for sebocyte differentiation and stratified squamous differentiation in adult mouse skin

PLoS One, 5(3).

By: J. House, S. Zhu, R. Ranjan, K. Linder & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Overexpression of transcription factor Sp2 inhibits epidermal differentiation and increases susceptibility to wound- and carcinogen-induced tumorigenesis

Cancer Research, 70(21), 8507–8516.

By: T. Kim, S. Chiera, K. Linder, C. Trempus, R. Smart & J. Horowitz

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

RSK-mediated phosphorylation in the C/EBP beta Leucine zipper regulates DNA binding, dimerization, and growth arrest activity

Molecular and Cellular Biology, 30(11), 2621–2635.

By: S. Lee, J. Shuman, T. Guszczynski, K. Sakchaisri, T. Sebastian, T. Copeland, M. Miller, M. Cohen ...

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

C/EBP alpha expression is partially regulated by C/EBP beta in response to DNA damage and C/EBP alpha-deficient fibroblasts display an impaired G(1) checkpoint

Oncogene, 28(36), 3235–3245.

By: R. Ranjan, E. Thompson, K. Yoon & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2008 journal article

C/EBP beta represses p53 to promote cell survival downstream of DNA damage independent of oncogenic Ras and p19(Arf)

Cell Death and Differentiation, 15(11), 1734–1744.

By: S. Ewing, S. Zhu, F. Zhu, J. House & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Decreased survival of C/EBP beta-deficient keratinocytes is due to aberrant regulation of p53 levels and function

Oncogene, 26(3), 360–367.

By: K. Yoon, S. Zhu, S. Ewing & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Genetic ablation of CCAAT/Enhancer binding protein alpha in epidermis reveals its role in suppression of epithelial tumorigenesis

Cancer Research, 67(14), 6768–6776.

By: K. Loomis, S. Zhu, K. Yoon, P. Johnson & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Conditional ablation of C/EBP beta demonstrates its keratinocyte-specific requirement for cell survival and mouse skin tumorigenesis

Oncogene, 25(8), 1272–1276.

By: E. Sterneck, S. Zhu, A. Ramirez, J. Jorcano & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

TAK1 is a master regulator of epidermal homeostasis involving skin inflammation and apoptosis

Journal of Biological Chemistry, 281(28), 19610–19617.

By: E. Omori, K. Matsumoto, H. Sanjo, S. Sato, S. Akira, R. Smart, J. Ninomiya-Tsuji

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Diminished expression of C/EBP alpha in skin carcinomas is linked to oncogenic Ras and reexpression of C/EBP alpha in carcinoma cells inhibits proliferation

Cancer Research, 65(3), 861–867.

By: M. Shim, K. Powers, S. Ewing, S. Zhu & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

C/EBP alpha is a DNA damage-inducible p53-regulated mediator of the G(1) checkpoint in keratinocytes

Molecular and Cellular Biology, 24(24), 10650–10660.

By: K. Yoon & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Cell cycle-dependent phosphorylation of C/EBP beta mediates oncogenic cooperativity between C/EBP beta and H-Ras(V12)

Molecular and Cellular Biology, 24(17), 7380–7391.

By: J. Shuman, T. Sebastian, P. Kaldis, T. Copeland, S. Zhu, R. Smart, P. Johnson

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Lithium stabilizes the CCAAT/enhancer-binding protein alpha (C/EBP alpha) through a glycogen synthase kinase 3 (GSK3)- independent pathway involving direct inhibition of proteasomal activity

Journal of Biological Chemistry, 278(22), 19674–19681.

By: M. Shim & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2003 patent

Method of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

17 beta-estradiol is a hormonal regulator of mirex tumor promotion sensitivity in mice

Toxicological Sciences, 69(1), 42–48.

By: K. Porter, S. Chanda, H. Wang, K. Gaido, R. Smart & C. Robinette

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

CCAAT/enhancer binding protein-beta is a mediator of keratinocyte survival and skin tumorigenesis involving oncogenic Ras signaling

Proceedings of the National Academy of Sciences of the United States of America, 99(1), 207–212.

By: S. Zhu, K. Yoon, E. Sterneck, P. Johnson & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Deficiency of either cyclooxygenase (COX)-1 or COX-2 alters epidermal differentiation and reduces mouse skin tumorigenesis

Cancer Research, 62(12), 3395–3401.

By: H. Tiano, C. Loftin, J. Akunda, C. Lee, J. Spalding, A. Sessoms, D. Dunson, E. Rogan ...

Source: NC State University Libraries
Added: August 6, 2018

2001 patent

Method of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Protein kinase C-alpha coordinately regulates cytosolic phospholipase A(2) activity and the expression of cyclooxygenase-2 through different mechanisms in mouse keratinocytes

Molecular Pharmacology, 59(4), 860–866.

By: H. Wang, M. Kim, H. Tiano, R. Langenbach & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

17 beta-Estradiol and ICI-182780 regulate the hair follicle cycle in mice through an estrogen receptor-alpha pathway

American Journal of Physiology, 278(2), E202–210.

By: S. Chanda, C. Robinette, J. Couse & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

A multihit, multistage model of chemical carcinogenesis

Carcinogenesis, 20(9), 1837–1844.

By: D. Owens, S. Wei & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

C/EBP beta modulates the early events of keratinocyte differentiation involving growth arrest and keratin 1 and keratin 10 expression

Molecular and Cellular Biology, 19(10), 7181–7190.

By: S. Zhu, H. Oh, M. Shim, E. Sterneck, P. Johnson & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Correlation between expression of peroxisome proliferator- activated receptor beta and squamous differentiation in epidermal and tracheobronchial epithelial cells

Molecular and Cellular Endocrinology, 147(1-2), 85–92.

By: H. Matsuura, H. Adachi, R. Smart, X. Xu, J. Arata & A. Jetten

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Effects of 17-beta-estradiol and ICI 182 780 on hair growth in various strains of mice

Journal of Investigative Dermatology, 4(3), 285–289.

By: R. Smart, H. Oh, S. Chanda & C. Robinette

Source: NC State University Libraries
Added: August 6, 2018

1999 patent

Methods of treating alopecia

Washington, DC: U.S. Patent and Trademark Office.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Overexpression of protein kinase C-[alpha] in the epidermis of transgenic mice results in striking alterations in phorbol ester-induced inflammation and COX-2, MIP-2, and TNF-[alpha] but not tumor promotion

Journal of Cell Science, 112(20), 3497–3506.

By: H. Wang & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Expression of CCAAT/enhancer binding proteins (C/EBP) is associated with squamous differentiation in epidermis and isolated primary keratinocytes and is altered in neoplasms

Journal of Investigative Dermatology, 110(6), 939–945.

By: H. Oh & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1998 personal communication

On the effect of estrogen receptor agonists and antagonists on the mouse hair follicle cycle

Journal of Investigative Dermatology.

By: R. Smart & H. Oh

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Evidence that mirex promotes a unique population of epidermal cells that cannot be distinguished by their mutant Ha ras genotype

Molecular Carcinogenesis, 20(1), 115–124.

By: T. Kim, K. Porter, J. Foley, R. Maronpot & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

Synergistic interaction between the non-phorbol ester type promoter mirex and 12-O-tetradecanoylphorbol-13-acetate in mouse skin tumor promotion

Carcinogenesis, 15, 47–52.

By: S. Meyer, T. Kim, G. Moser, N. Monteiro-Riviere & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Minimal role of enhanced cell proliferation in skin tumor promotion by mirex, a new nonphorbol ester-type promoter

Environmental Health Perspectives, 101(Suppl. 5), 265–270.

By: S. Meyer, G. Moser, N. Monteiro-Riviere & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1991 journal article

Effect of ascorbic acid and its synthetic lipophilic derivative ascorbyl palmitate on phorbol ester-induced skin-tumor promotion in mice

American Journal of Clinical Nutrition, 54, 1266.

By: R. Smart & C. Crawford

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Differential down-regulation of epidermal protein kinase C (PKC) by tetradecanoylphorbol-13-acetate and diacylglycerol: Association with epidermal hyperplasia and tumor promotion

Cancer Research, 50, 5740–5745.

By: L. Hansen, N. Monteiro-Riviere & R. Smart

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Comparison of the effect of sn-1,2-didecanoylglycerol and 12-o-tetradecanoylphorbol-13-acetate on cutaneous morphology, inflammation and tumor promotion in CD 1 mice

Carcinogenesis, 9, 2221–2226.

By: R. Smart, M. Huang, N. Monteiro-Riviere, C. Wong, K. Mills & A. Conney

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Inhibitory effect of curcumin, chlorogenic acid, caffeic acid, and ferulic acid on tumor promotion in mouse skin by 12-o-tetradecanoylphorbol-13-acetate

Cancer Research, 48(21), 5941–5946.

By: M. Huang, R. Smart, C. Wong & A. Conney

Source: NC State University Libraries
Added: August 6, 2018