Rafael Guerrero

Jain, S., Bakolitsa, C., Brenner, S. E., Radivojac, P., Moult, J., Repo, S., … Zook, J. M. (2024). CAGI, the Critical Assessment of Genome Interpretation, establishes progress and prospects for computational genetic variant interpretation methods. GENOME BIOLOGY, 25(1). https://doi.org/10.1186/s13059-023-03113-6

Ogbunugafor, C. B., Guerrero, R. F., Miller-Dickson, M. D., Shakhnovich, E. I., & Shoulders, M. D. (2023). Epistasis and pleiotropy shape biophysical protein subspaces associated with drug resistance. PHYSICAL REVIEW E, 108(5). https://doi.org/10.1103/PhysRevE.108.054408

Ogbunugafor, C. B., Guerrero, R. F., Shakhnovich, E. I., & Shoulders, M. D. (2023, April 9). Epistasis meets pleiotropy in shaping biophysical protein subspaces associated with antimicrobial resistance. https://doi.org/10.1101/2023.04.09.535490

Guerrero, R. F., Dorji, T., Harris, R. M. M., Shoulders, M. D., & Ogbunugafor, C. B. (2023, April 8). Evolutionary druggability: leveraging low-dimensional fitness landscapes towards new metrics for antimicrobial applications. https://doi.org/10.1101/2023.04.08.536116

Guerrero, R. F., Dorji, T., Harris, R. M. M., Shoulders, M. D., & Ogbunugafor, C. B. (2023, August 14). Evolutionary druggability: leveraging low-dimensional fitness landscapes towards new metrics for antimicrobial applications. https://doi.org/10.7554/eLife.88480.1

Guerrero, R. F., Dorji, T., Harris, R. M. M., Shoulders, M. D., & Ogbunugafor, C. B. (2023, November 30). Evolutionary druggability: leveraging low-dimensional fitness landscapes towards new metrics for antimicrobial applications. https://doi.org/10.7554/eLife.88480.2

Yan, Q., Blue, N. R., Truong, B., Zhang, Y., Guerrero, R. F., Liu, N., … Haas, D. M. (2023, May 30). Genetic Associations with Dynamic Placental Proteins Identify Causal Biomarkers for Hypertension in Pregnancy. https://doi.org/10.1101/2023.05.25.23290460

Honigberg, M. C., Truong, B., Khan, R. R., Xiao, B., Bhatta, L., Vy, H. M. T., … Natarajan, P. (2023, May 29). Polygenic prediction of preeclampsia and gestational hypertension. NATURE MEDICINE, Vol. 5. https://doi.org/10.1038/s41591-023-02374-9

Yan, Q., Guerrero, R. F., Khan, R. R., Surujnarine, A. A., Wapner, R. J., Hahn, M. W., … Haas, D. M. (2023, June 5). Searching and visualizing genetic associations of pregnancy traits by using GnuMoM2b. https://doi.org/10.1101/2023.05.25.23290500

Yan, Q., Guerrero, R. F., Khan, R. R., Surujnarine, A. A., Wapner, R. J., Hahn, M. W., … Haas, D. M. (2023). Searching and visualizing genetic associations of pregnancy traits by using GnuMoM2b. GENETICS, 225(2). https://doi.org/10.1093/genetics/iyad151

Pagel, K. A., Chu, H., Ramola, R., Guerrero, R. F., Chung, J. H., Parry, S., … Radivojac, P. (2022). Association of Genetic Predisposition and Physical Activity With Risk of Gestational Diabetes in Nulliparous Women. JAMA NETWORK OPEN, 5(8). https://doi.org/10.1001/jamanetworkopen.2022.29158

Guerrero, R. F., Khan, R. R., Wapner, R. J., Hahn, M. W., Raja, A., Salleb-Aouissi, A., … Haas, D. M. (2022, March 1). Genetic Polymorphisms Associated with Adverse Pregnancy Outcomes in Nulliparas. https://doi.org/10.1101/2022.02.28.22271641

Honigberg, M. C., Truong, B., Khan, R. R., Xiao, B., Bhatta, L., Vy, T. H., … Natarajan, P. (2022, December 1). Genome-wide meta-analysis identifies novel maternal risk variants and enables polygenic prediction of preeclampsia and gestational hypertension. https://doi.org/10.1101/2022.11.30.22282929

Pagel, K. A., Chu, H., Ramola, R., Guerrero, R. F., Chung, J. H., Parry, S., … Radivojac, P. (2022, March 9). The influence of genetic predisposition and physical activity on risk of Gestational Diabetes Mellitus in the nuMoM2b cohort. https://doi.org/10.1101/2022.03.08.22271868

Wu, M., Haak, D. C., Anderson, G. J., Hahn, M. W., Moyle, L. C., & Guerrero, R. F. (2021). Inferring the Genetic Basis of Sex Determination from the Genome of a Dioecious Nightshade. MOLECULAR BIOLOGY AND EVOLUTION, 38(7), 2946–2957. https://doi.org/10.1093/molbev/msab089

Stamboulian, M., Guerrero, R. F., Hahn, M. W., & Radivojac, P. (2020, July). The ortholog conjecture revisited: the value of orthologs and paralogs in function prediction. BIOINFORMATICS, Vol. 36, pp. 219–226. https://doi.org/10.1093/bioinformatics/btaa468

Kasak, L., Hunter, J. M., Udani, R., Bakolitsa, C., Hu, Z., Adhikari, A. N., … Meyn, M. S. (2019). CAGI SickKids challenges: Assessment of phenotype and variant predictions derived from clinical and genomic data of children with undiagnosed diseases. Human Mutation, 40(9), 1373–1391. https://doi.org/10.1002/humu.23874

Guerrero, R. F., Scarpino, S. V., Rodrigues, J. V., Hartl, D. L., & Ogbunugafor, C. B. (2019). Proteostasis Environment Shapes Higher-Order Epistasis Operating on Antibiotic Resistance. Genetics, 212(2), 565–575. https://doi.org/10.1534/genetics.119.302138

Berrio, A., Guerrero, R. F., Aglyamova, G. V., Okhovat, M., Matz, M. V., & Phelps, S. M. (2018). Complex selection on a regulator of social cognition: Evidence of balancing selection, regulatory interactions and population differentiation in the prairie vole Avpr1a locus. Molecular Ecology. https://doi.org/10.1111/mec.14455

Guerrero, R. F., & Hahn, M. W. (2018). Quantifying the risk of hemiplasy in phylogenetic inference. Proceedings of the National Academy of Sciences, 115(50), 12787–12792. https://doi.org/10.1073/pnas.1811268115

Guerrero, R. F., Muir, C. D., Josway, S., & Moyle, L. C. (2017). Pervasive antagonistic interactions among hybrid incompatibility loci. PLOS Genetics, 13(6), e1006817. https://doi.org/10.1371/journal.pgen.1006817

Guerrero, R. F., & Hahn, M. W. (2017). Speciation as a Sieve for Ancestral Polymorphism. Molecular Ecology, 8. https://doi.org/10.1111/mec.14290

Marais, D. L. D., Guerrero, R. F., Lasky, J. R., & Scarpino, S. V. (2017). Topological features of a gene co-expression network predict patterns of natural diversity in environmental response. Proceedings of the Royal Society B: Biological Sciences, 284(1856), 20170914. https://doi.org/10.1098/rspb.2017.0914

Transcriptomic analysis links gene expression to unilateral pollen-pistil reproductive barriers. (2017). BMC Plant Biology, 4. https://doi.org/10.1186/s12870-017-1032-4

Guerrero, R. F., Posto, A. L., Moyle, L. C., & Hahn, M. W. (2016). Genome-wide patterns of regulatory divergence revealed by introgression lines. Evolution, 70(3), 696–706. https://doi.org/10.1111/evo.12875

Pease, J. B., Guerrero, R. F., Sherman, N. A., Hahn, M. W., & Moyle, L. C. (2016). Molecular mechanisms of postmating prezygotic reproductive isolation uncovered by transcriptome analysis. Molecular Ecology, 25(11), 2592–2608. https://doi.org/10.1111/mec.13679

Guerrero, R. F., & Kirkpatrick, M. (2014). LOCAL ADAPTATION AND THE EVOLUTION OF CHROMOSOME FUSIONS. Evolution, 68(10), 2747–2756. https://doi.org/10.1111/evo.12481

Matrix inversions for chromosomal inversions: A method to construct summary statistics in complex coalescent models. (2014). Theoretical Population Biology. https://doi.org/10.1016/j.tpb.2014.07.005

Signatures of sex-antagonistic selection on recombining sex chromosomes. (2014). Genetics, 6. https://doi.org/10.1534/genetics.113.156026

Strong reinforcing selection in a Texas wildflower. (2014). Current Biology : CB, 9. https://doi.org/10.1016/j.cub.2014.07.027

A sequential coalescent algorithm for chromosomal inversions. (2013). Heredity, 9. https://doi.org/10.1038/hdy.2013.38

Coalescent patterns for chromosomal inversions in divergent populations. (2012). Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 2. https://doi.org/10.1098/rstb.2011.0246

Cryptic recombination in the ever-young sex chromosomes of Hylid frogs. (2012). Journal of Evolutionary Biology, 10. https://doi.org/10.1111/j.1420-9101.2012.02591.x

Ayala, D., Guerrero, R. F., & Kirkpatrick, M. (2012). REPRODUCTIVE ISOLATION AND LOCAL ADAPTATION QUANTIFIED FOR A CHROMOSOME INVERSION IN A MALARIA MOSQUITO. Evolution, 67(4), 946–958. https://doi.org/10.1111/j.1558-5646.2012.01836.x

About PAR: the distinct evolutionary dynamics of the pseudoautosomal region. (2011). Trends in Genetics : TIG, 9. https://doi.org/10.1016/j.tig.2011.05.001

Patterns of neutral genetic variation on recombining sex chromosomes. (2010). Genetics, 4. https://doi.org/10.1534/genetics.109.113555