Works (34)

Updated: July 5th, 2023 16:02

2021 journal article

Functional Diversification, Redundancy, and Epistasis among Paralogs of the Drosophila melanogaster Obp50a-d Gene Cluster

MOLECULAR BIOLOGY AND EVOLUTION, 38(5), 2030โ€“2044.

By: J. Johnstun n, V. Shankarโ€‰*, S. Mokashiโ€‰ n, L. Sunkaraโ€‰*, U. Ihearahu*, R. Lyman*, T. Mackay n, R. Anholt n

co-author countries: United Kingdom of Great Britain and Northern Ireland ๐Ÿ‡ฌ๐Ÿ‡ง United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: multigene families; functional diversification; transcriptional niche; RNAseq; odorant-binding proteins; evolutionary genetics
MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Epistasis, Genetic; Evolution, Molecular; Fat Body / metabolism; Female; Genitalia, Male / metabolism; Male; Multigene Family; Phenotype; Pupa / metabolism; Receptors, Odorant / genetics; Receptors, Odorant / metabolism
Source: Web Of Science
Added: June 10, 2021

2020 journal article

Gene expression networks in the Drosophila Genetic Reference Panel

GENOME RESEARCH, 30(3), 485โ€“496.

By: L. Everett n, W. Huang n, S. Zhou n, M. Carbone n, R. Lyman n, G. Arya n, M. Geisz n, J. Maโ€‰* ...

co-author countries: China ๐Ÿ‡จ๐Ÿ‡ณ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Drosophila melanogaster / microbiology; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Variation; High-Throughput Nucleotide Sequencing; Male; Microbiota / genetics; Quantitative Trait Loci; Sequence Analysis, RNA
Source: Web Of Science
Added: April 14, 2020

2020 journal article

Genotype by environment interaction for gene expression in Drosophila melanogaster

NATURE COMMUNICATIONS, 11(1).

By: W. Huang n, M. Carbone n, R. Lyman n, R. Anholt n & T. Mackay n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Drosophila melanogaster / genetics; Female; Gene Expression; Gene Expression Regulation; Gene Regulatory Networks; Gene-Environment Interaction; Genes, Insect; Genetic Variation; Genotype; Male; Quantitative Trait Loci; RNA-Seq; Temperature; Transcriptome
Source: Web Of Science
Added: November 30, 2020

2014 journal article

Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines

Genome Research, 24(7), 1193โ€“1208.

By: W. Huang, A. Massouras, Y. Inoue, J. Peiffer, M. Ramia, A. Tarone, L. Turlapati, T. Zichner ...

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Co-regulated transcriptional networks contribute to natural genetic variation in Drosophila sleep

NATURE GENETICS, 41(3), 371โ€“375.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Animals, Genetically Modified; Animals, Inbred Strains; Drosophila / genetics; Drosophila Proteins / genetics; Female; Gene Expression Regulation / physiology; Gene Regulatory Networks / physiology; Genes, Insect; Genetic Variation / physiology; Genome, Insect; Genome-Wide Association Study / veterinary; Male; Models, Biological; Molecular Sequence Data; Polymorphism, Genetic; Sleep / genetics
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Systems genetics of complex traits in Drosophila melanogaster

NATURE GENETICS, 41(3), 299โ€“307.

By: J. Ayroles n, M. Carbone n, E. Stoneโ€‰ n, K. Jordan n, R. Lyman n, M. Magwire n, S. Rollmann n, L. Duncan n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Animals; Animals, Inbred Strains; Base Sequence; Chromosome Mapping; Drosophila melanogaster / genetics; Female; Gene Regulatory Networks / physiology; Genetic Variation / physiology; Genetics, Population / methods; Male; Molecular Sequence Data; Phenotype; Quantitative Trait, Heritable; RNA, Messenger / analysis; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Homology, Amino Acid; Tissue Distribution
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila

GENETICS, 177(3), 1655โ€“1665.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Benzaldehydes; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Genes, Insect; Genetics, Population; Male; Models, Molecular; Molecular Sequence Data; Multigene Family; Nucleic Acid Conformation; Odorants; Phenotype; Polymorphism, Genetic; Polymorphism, Single Nucleotide; RNA Precursors / chemistry; RNA Precursors / genetics; Receptors, Odorant / genetics
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Candidate genes affecting Drosophila life span identified by integrating microarray gene expression analysis and QTL mapping

MECHANISMS OF AGEING AND DEVELOPMENT, 128(3), 237โ€“249.

By: C. Lai*, L. Parnellโ€‰*, R. Lyman n, J. Ordovasโ€‰* & T. Mackay n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: life span; microarray gene expression; QTL; Drosophila aging
MeSH headings : Aging / genetics; Aging / physiology; Animals; Biomarkers; Chromosome Mapping; Cytochrome P-450 Enzyme System / genetics; Drosophila / genetics; Drosophila / physiology; Energy Metabolism / genetics; Gene Expression Regulation / physiology; Intercellular Signaling Peptides and Proteins / genetics; Longevity / genetics; Oligonucleotide Array Sequence Analysis; Oxidoreductases / genetics; Quantitative Trait Loci / genetics; Signal Transduction / genetics; Signal Transduction / physiology; Transcription, Genetic; Ubiquitin / genetics
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Phenotypic variation and natural selection at Catsup, a pleiotropic quantitative trait gene in Drosphila

CURRENT BIOLOGY, 16(9), 912โ€“919.

By: M. Carbone n, K. Jordan n, R. Lyman n, S. Harbisonโ€‰ n, J. Leips*, T. Morgan n, M. DeLuca n, P. Awadalla n, T. Mackay n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Catecholamines / metabolism; Drosophila / anatomy & histology; Drosophila / genetics; Drosophila Proteins / chemistry; Drosophila Proteins / genetics; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Female; Genetic Variation; Genotype; Longevity / genetics; Male; Molecular Sequence Data; Motor Activity / genetics; Phenotype; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Relationships between the phagocytic ability of milk macrophages and polymorphonuclear cells and somatic cell counts in uninfected cows

Canadian Journal of Veterinary Research, 70(1), 68โ€“74.

By: A. Rivas, R. Tadevosyan, R. Gorewit, K. Anderson, R. Lyman & R. Gonzalez

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Drosophila bristles and the nature of quantitative genetic variation

Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, 360(1459), 1513โ€“1527.

By: T. Mackay & R. Lyman

Source: NC State University Libraries
Added: August 6, 2018

2005 article

Genetics and genomics of Drosophila mating behavior

Mackay, T. F. C., Heinsohn, S. L., Lyman, R. F., Moehring, A. J., Morgan, T. J., & Rollmann, S. M. (2005, May 3). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 102, pp. 6622โ€“6629.

By: T. Mackay n, S. Heinsohn n, R. Lyman n, A. Moehring n, T. Morgan n & S. Rollmann n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Chromosomes; Copulation / physiology; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Genes, Insect / genetics; Genomics; Male; Phenotype; Sexual Behavior, Animal / physiology; Transcription, Genetic / genetics
Source: Web Of Science
Added: August 6, 2018

2005 journal article

Polygenic mutation in Drosophila melanogaster: Mapping spontaneous mutations affecting sensory bristle number

GENETICS, 170(4), 1723โ€“1735.

By: T. Mackay n, R. Lyman n & F. Lawrence n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Chromosome Mapping; Drosophila melanogaster / genetics; Genes, Insect; Genetic Complementation Test; Genetic Variation; Genome, Insect; Mutation; Quantitative Trait Loci; Quantitative Trait, Heritable; Selection, Genetic; X Chromosome
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Dopa decarboxylase (Ddc) affects variation in Drosophila longevity

NATURE GENETICS, 34(4), 429โ€“433.

co-author countries: Italy ๐Ÿ‡ฎ๐Ÿ‡น Russian Federation ๐Ÿ‡ท๐Ÿ‡บ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Base Sequence; Chromosome Mapping; DNA / genetics; Dopa Decarboxylase / genetics; Drosophila melanogaster / enzymology; Drosophila melanogaster / genetics; Female; Genes, Insect; Genetic Complementation Test; Genetic Variation; Longevity / genetics; Male; Molecular Sequence Data; Mutation; Polymorphism, Genetic; Quantitative Trait Loci; Sequence Homology, Nucleic Acid; Species Specificity
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Quantitative analysis of bristle number in Drosophila mutants identifies genes involved in neural development

CURRENT BIOLOGY, 13(16), 1388โ€“1397.

By: K. Norga*, M. Gurganus n, C. Dilda n, A. Yamamoto n, R. Lyman n, P. Patel*, G. Rubinโ€‰*, R. Hoskins*, T. Mackay n, H. Bellenโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Drosophila / anatomy & histology; Drosophila / genetics; Drosophila / growth & development; Gene Expression Regulation, Developmental; Genes, Insect; Mutation; Peripheral Nerves / growth & development
Source: Web Of Science
Added: August 6, 2018

2003 journal article

Transcription profiling in Drosophila eyes that overexpress the human glaucoma-associated trabecular meshwork-inducible glucocorticoid response protein/myocilin (TIGR/MYOC)

Genetics, 163(2), 637โ€“645.

By: T. Borras, T. Morozova, S. Heinsohn, R. Lyman, T. Mackay & R. Anholt

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Impaired olfactory behavior in mice deficient in the a subunit of G(0)

BRAIN RESEARCH, 941(1-2), 62โ€“71.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: G protein; knock-out mouse; olfaction; chemoreception; behavioral genetics; olfactory bulb
MeSH headings : Analysis of Variance; Animals; Behavior, Animal; Female; GTP-Binding Protein alpha Subunits; Heterotrimeric GTP-Binding Proteins / deficiency; Heterotrimeric GTP-Binding Proteins / genetics; Immunohistochemistry; Male; Mice; Mice, Knockout; Odorants; Olfactory Bulb / cytology; Olfactory Receptor Neurons; Phenotype; Smell / genetics
Source: Web Of Science
Added: August 6, 2018

2002 journal article

The hairy: A quantitative trait locus for Drosophila sensory bristle number

Genetics, 162(1), 155โ€“164.

By: C. Robin, R. Lyman, A. Long, C. Langley & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Variation in Drosophila sensory bristle number at 'Evolution Canyon'

GENETICS RESEARCH, 80(3), 215โ€“223.

co-author countries: Israel ๐Ÿ‡ฎ๐Ÿ‡ฑ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Drosophila / anatomy & histology; Drosophila / genetics; Female; Genetic Variation; Male
Source: Web Of Science
Added: August 6, 2018

2000 journal article

Both naturally occurring insertions of transposable elements and intermediate frequency polymorphisms at the achaete-scute complex are associated with variation in bristle number in Drosophila melanogaster

Genetics, 154(3), 1255โ€“1269.

By: A. Long, R. Lyman, A. Morgan, C. Langley & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Genotype-environment interaction for quantitative trait loci affecting life span in Drosophila melanogaster

Genetics, 154(1), 213โ€“227.

By: C. Vieira, E. Pasyukova, Z. Zeng, J. Hackett, R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Linkage disequilibrium mapping of molecular polymorphisms at the scabrous locus associated with naturally occurring variation in bristle number in Drosophila melanogaster

GENETICS RESEARCH, 74(3), 303โ€“311.

By: R. Lyman n, C. Lai n & T. Mackay n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Chromosome Mapping; Drosophila Proteins; Drosophila melanogaster / anatomy & histology; Drosophila melanogaster / genetics; Female; Glycoproteins / genetics; Insect Proteins / genetics; Linkage Disequilibrium; Male; Phenotype; Polymorphism, Genetic; Quantitative Trait, Heritable
Source: Web Of Science
Added: August 6, 2018

1998 journal article

Candidate quantitative trait loci and naturally occurring phenotypic variation for bristle number in Drosophila melanogaster: The Delta-Hairless gene region

Genetics, 149(2), 983โ€“998.

By: R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Genotype-environment interaction at quantitative trait loci affecting sensory bristle number in Drosophila melanogaster

Genetics, 149(4), 1883โ€“1898.

By: M. Gurganus, J. Fry, S. Nuzhdin, E. Pasyukova, R. Lyman & T. MacKay

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Two sites in the Delta gene region contribute to naturally occurring variation in bristle number in Drosophila melanogaster

Genetics, 149(2), 999โ€“1017.

By: A. Long, R. Lyman, C. Langley & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

A transcriptional network associated with natural variation in Drosophila aggressive behavior

Edwards, A. C., Ayroles, J. F., Stone, E. A., Carbone, M. A., Lyman, R. F., & Mackay, T. F. C. Genome Biology, 10(7).

By: A. Edwards, J. Ayroles, E. Stone, M. Carbone, R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Genetic architecture of abdominal pigmentation in Drosophila melanogaster

Dembeck, L. M., Huang, W., Magwire, M. M., Lawrence, F., Lyman, R. F., & Mackay, T. F. C. PLoS Genetics, 11(5).

By: L. Dembeck, W. Huang, M. Magwire, F. Lawrence, R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Genetic basis of transcriptome diversity in Drosophila melanogaster

Huang, W., Carbone, M. A., Magwire, M. M., Peiffer, J. A., Lyman, R. F., Stone, E. A., โ€ฆ Mackay, T. F. C. Proceedings of the National Academy of Sciences of the United States of America, 112(44), E6010โ€“6019.

By: W. Huang, M. Carbone, M. Magwire, J. Peiffer, R. Lyman, E. Stone, R. Anholt, T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Genetic variation in senescence marker protein-30 is associated with natural variation in cold tolerance in Drosophila

Clowers, K. J., Lyman, R. F., Mackay, T. F. C., & Morgan, T. J. Genetical Research, 92(2), 103โ€“113.

By: K. Clowers, R. Lyman, T. Mackay & T. Morgan

Source: NC State University Libraries
Added: August 6, 2018

journal article

Genomic response to selection for postponed senescence in Drosophila

Wilson, R. H., Lai, C. Q., Lyman, R. F., & Mackay, T. F. C. Mechanisms of Ageing and Development, 134(3-4), 79โ€“88.

By: R. Wilson, C. Lai, R. Lyman & T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

Natural variation in odorant recognition among odorant-binding proteins in Drosophila melanogaster

Wang, P., Lyman, R. F., Mackay, T. F. C., & Anholt, R. R. H. Genetics, 184(3), 759โ€“767.

By: P. Wang, R. Lyman, T. Mackay & R. Anholt

Source: NC State University Libraries
Added: August 6, 2018

journal article

Polygenic mutation in Drosophila melanogaster: Genotype x environment interaction for spontaneous mutations affecting bristle number

Mackay, T. F. C., & Lyman, R. F. Genetica, 102-103(1-6), 199โ€“215.

By: T. Mackay & R. Lyman

Source: NC State University Libraries
Added: August 6, 2018

journal article

Spontaneous mutations and the origin and maintenance of quantitative genetic variation

Huang, W., Lyman, R. F., Lyman, R. A., Carbone, M. A., Harbison, S. T., Magwire, M. M., & Mackay, T. F. C. Elife, 5.

By: W. Huang, R. Lyman, R. Lyman, M. Carbone, S. Harbison, M. Magwire, T. Mackay

Source: NC State University Libraries
Added: August 6, 2018

journal article

The Drosophila melanogaster genetic reference panel

Mackay, T. F. C., Richards, S., Stone, E. A., Barbadilla, A., Ayroles, J. F., Zhu, D. H., โ€ฆ Carbone, M. A. Nature, 482(7384), 173โ€“178.

By: T. Mackay, S. Richards, E. Stone, A. Barbadilla, J. Ayroles, D. Zhu, S. Casillas, Y. Han ...

Source: NC State University Libraries
Added: August 6, 2018